Conserved Protein Domain Family
Cse1_I-E

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cd09729: Cse1_I-E 
CRISPR/Cas system-associated protein Cse1
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family
Statistics
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PSSM-Id: 187860
Aligned: 55 rows
Threshold Bit Score: 259.593
Created: 23-Nov-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q1GAI7         4 YNLITEPWIKVLdgktnsEHMVSIKELLq----nASDYRQLAGeMHAQDLAVLRLLEAILTTVytrVDQNDeeyewvtld 79  Lactobacillus d...
Q12YB1         3 FNLIHEKWIWVQrqd-gtRSMIAPWQITde--igSNPIISLDEpRPDFNGSMIQFLIGLVQTT---MSPKSd-------- 68  Methanococcoide...
Q2FNL5         2 IHLLHDAWIPVVrkn-gdSGLIAPHQITsd--ydTNPVIELNAsRPDFNGALIQFLIGLIQTV---CPPESd-------- 67  Methanospirillu...
Q314I1         4 LNILSDQWLPVIlad-gkRIRIAPWELTa-----DPRPVALDIpRPDFGGAMLEFLVGCMQTM---CPPQSr-------- 66  Desulfovibrio d...
Q054L1         1 MNLIKDVWIPVQrfs-ekLEEISPFEITsriendSDPVMSLSApRPDFNGALLQFLVGLLQAV---FSPENe-------- 68  Leptospira borg...
YP_001234934   2 FNLLTNPWLPIVrqd-gtKSVIAPRDITed--isSNPVIAVNWpRADFRLATMELLVGLIATA---CPPADe-------- 67  Acidiphilium cr...
Q2RY16         3 FNLLLERWLPVRrvs-gkRDWVAPHQLTeg--faEDPIVGLDFpRADFNAAVLEFLIGVVYVA---LPCQKa-------- 68  Rhodospirillum ...
Q0BSC4        23 LNLIDDQWIPVLcad-gsRRVIAPWQMA------EPDVVQPDWpRPDLNIACLELLIGLVFLA---DPPVDg-------- 84  Granulibacter b...
Q74DD1         1 MNLLTEAWIPVRplpagaACKLTLRQLLc-----EDGRWELCLpRDDMELAALQLLICMTQVF---FPPQSt-------- 64  Geobacter sulfu...
ZP_01313573    1 MNLLSDAWIPVRlqgkasAQKLTVRQLLc-----GDEHWELCLpRDDMELAALQLLICLTQAL---ATPDNa-------- 64  Desulfuromonas ...
Q1GAI7        80 eqmhvqsyddeiegstllqvltKTWNALYkegSFSEAVFDYLDKNKGLFDFFGd--rPFYQVTAEqydsfvPDNKKIAKg 157 Lactobacillus d...
Q12YB1        69 ----------------------GKWRKRFispPTPEELLETFEKVAHVFDLDGdd-eRFMQDHEHi----eGAKNRVDA- 120 Methanococcoide...
Q2FNL5        68 ----------------------KEWTDRLdnvIPSDVLKGHFKQIQDAFSLDGkg-pRFMQDISIg----dEKKNSVDG- 119 Methanospirillu...
Q314I1        67 ----------------------KDWRSWRktpPQPQTLRTAMEPFIPHFHLLGer-pLFMQDLTLkq--eeENVMGVAA- 120 Desulfovibrio d...
Q054L1        69 ----------------------TEWEDLFvnpPSPEVLKEAMEKVKSAFELFGdg-pRFMQDTNLne---eDTVFDISA- 121 Leptospira borg...
YP_001234934  68 ----------------------DDWLDAWeapHSPEKLDGAFAPLAHAFSFDGpg-pRFMQDLADl----dADEEPVEN- 119 Acidiphilium cr...
Q2RY16        69 ----------------------ADWVKGSltpPAPATLQAALSPLAFAFDFDGdgprAYQDTSDLa----aADCRPITG- 121 Rhodospirillum ...
Q0BSC4        85 ----------------------EDWEARRd--PDPQRLQEKLAPYAPAFNLVGdg-pRFLQDLEPf----tGKASSVDM- 134 Granulibacter b...
Q74DD1        65 ----------------------AALKQRIvapLSLDEFESGCAPYREWFRLDHpd-fPFMQVRNVs----aKDPTPMDK- 116 Geobacter sulfu...
ZP_01313573   65 ----------------------TTLKQRIktpLTGELLDSAGKFFNDWFQLDHpt-sPFMQVRNVk----aKEPTPMDK- 116 Desulfuromonas ...
Q1GAI7       158 sGTVDLMQINRLIsqsgnsvaiFSPKSAnrknkLTLDELVRWVITYQNFtgVTDKTKVKakkkmsnSRGWLYTLnpv--- 234 Lactobacillus d...
Q12YB1       121 -LLMEMPGVQTLKhna----dhFQKRDTvt--qMCLPCCVTALFNLQLNa-PAGGQGHRts---lrGGGPLTTLv----- 184 Methanococcoide...
Q2FNL5       120 -LLIEMPGENTVKknt----dfFVKRDTvk--qMCPSCAAMALFTLQVNg-PGGGAGHKtg---lrGGGPLTSVi----- 183 Methanospirillu...
Q314I1       121 -LLIDSPGENAIKndt----dfFVKRGRie--tLCPACAAMALYTMQAFa-PSGGAGYRts---lrGGGPLSTLv----- 184 Desulfovibrio d...
Q054L1       122 -LFIESPGENTIKlkk----dfFIKRNSis--qICEKCAGIGLFSFQTNs-PSGGQGHLts---irGGGPLTTFvtskl- 189 Leptospira borg...
YP_001234934 120 -LLIEVAGNSGPLv--------HPGRTKr----MGRPAAAISLYTLQSWs-PSGGRGNRtg---lrGGGPMVTMvap--- 179 Acidiphilium cr...
Q2RY16       122 -LFIDFPGENTLKnna----dlFIKRRDas--aLCLPYAAAATITLQTYa-PSGGAGHRts---irGGGPLTTLvaprrr 190 Rhodospirillum ...
Q0BSC4       135 -LFIDSAAVETARkna----dvMVHRSRyd--rLDFPIAAMALYTFQSYa-PAGGAGNFts---mrGGGPMVTLvd---- 199 Granulibacter b...
Q74DD1       117 -LLAGLTGATNSC---------FVNEPGlg-acLCGGCAAIALFNQSSNa-PSFGGGFKgs---lrGGAPVTTLv----- 176 Geobacter sulfu...
ZP_01313573  117 -LLAGVTGATNSC---------FVNPSGlg-esLCAGCTAIALFNQAMNv-PGFGGGFKag---lrGGAPVTTLv----- 176 Desulfuromonas ...
Q1GAI7       235 ---yaqGKNLFETLMLNLLLfnpnk----------paytqQRPVWEEDl--gEYVKRRlsqv----kpdNFAETYTVWSR 295 Lactobacillus d...
Q12YB1       185 -----lGSNLWQTIWLNVISdenfkglg----dvdnceisDIYPWMGPt---RTSEKKnamtt--pmdvNPKQMYWGMPR 250 Methanococcoide...
Q2FNL5       184 -----lGETLWETVWLNIIPsikffgdai---akqkksmdMIFPWFGKi---RLSDKKektg---vidvNPLQMFWGMGR 249 Methanospirillu...
Q314I1       185 -----lGETLWETVWNNVLVaestdwri----pdghdplgRILPWTVPt---RDSKKKgtail--patgHNLLHFWAMPR 250 Desulfovibrio d...
Q054L1       190 --knpkKNSLWSKLWLNVLPksyfqvng-----qkkipfqSVFPWTNP----KIEDLQskgktttpqdlHPLSVYWSYPR 258 Leptospira borg...
YP_001234934 180 ----grHRSLWHHIWANVPLgrkpe----------pvdfpRIFPWLSPti-tSVNDEVvtpd----dvaHPLQVWWGMPR 240 Acidiphilium cr...
Q2RY16       191 lagggeVATLWDRIWANVPDqkwdgsdpiagdpadhanwpLVFPWLAA----AITSSHgqiva--padaTKRQSFFGCPR 264 Rhodospirillum ...
Q0BSC4       200 -----pERMLWDLVWVNVSCghs--------------akmETLPWMRPtrvsHTGQQTlppd----gelFGAEAFFGMPR 256 Granulibacter b...
Q74DD1       177 -----qGEHLRQTVWLNVLSeerltqii----pwhhatrsQQPTWVAPi---KAGETIpsq------aiGVLRGLFWQPG 238 Geobacter sulfu...
ZP_01313573  177 -----qGEHLRQTIWLNVLTeenidhll----pwhqktkkQKPTWIDPikpeTFAAQSi----------GFLRGLFWQPA 237 Desulfuromonas ...
Q1GAI7       296 LLHIew--------------------qdGTPTIFSAGLptfdsanaydiEPMSTWRmnk--kdeNYYPATRQlssiGIAM 353 Lactobacillus d...
Q12YB1       251 RIRLdlddliegacdv-cgcesdklvsnYVTKNYGYNYdgg------wcHVLSPHNen----knGLLPRHPQp---GGIT 316 Methanococcoide...
Q2FNL5       250 RILLdfedkpvgacdv-cglassatvltYHTKPHGVDYdet-----wdnHTLTPYYld----keVYRPIHLQp---GGIT 316 Methanospirillu...
Q314I1       251 RFRLhpenlsdpaacdicgtpsttvirqIGAKNYGNNYega------wqHPLTPYReqg--kgkLALSVKGAs---ECTA 319 Desulfovibrio d...
Q054L1       259 RILLrkdvengicdv--cnrsssvlvrsYHTKTYGLSYseg-----gwiHPLSPYYks----keSWFPYHPQp---GGIL 324 Leptospira borg...
YP_001234934 241 RIRLsfvqlpspapcdltgaldssvvtgWRQRPHGPKYvgw-----garHPLTPTYqnk--ageEILSVHPNp---GGVG 310 Acidiphilium cr...
Q2RY16       265 RLRLvfqqaspdhpcvlggpagaimavgFRTQNYGANYeg-------wtHPLSPYRddk---kaGRLPIHPHg---GAAT 331 Rhodospirillum ...
Q0BSC4       257 RLRLthneg---------------avtgVIQKPGGTDYal-------wkHPLSPYYrkk--sgeEWLPKHPRa---GHFG 309 Granulibacter b...
Q74DD1       239 HLELmppqgeqacic--cgfvekqvyagFNKAKFNYTIdgl------wpHPHGPRIssvkkgerEEKFVSFTt---AAPA 307 Geobacter sulfu...
ZP_01313573  238 HIELcqaeqggscsc--cgqhhvevyrgFNKAKFSYRIegl------wpHPHGARIvalkkgekEEKFVSFTt---TAPS 306 Desulfuromonas ...
Q1GAI7       354 WRNFGQYV------DIEGHtesrePLTVAWLnylktkn---eflnqqmINLHTSGIISnGGATSlmpaaefdDNLRIEAD 424 Lactobacillus d...
Q12YB1       317 YRHWLGLVq----hDPDKGly--sSLAFERFvqkqkdlsdlgdvfkntPQLWAFGYDF-DNMKVrc-----wYESTMPLF 384 Methanococcoide...
Q2FNL5       317 YRNFMGLIi----pDSSRNik--vSRTVTNFqnniirl---krksfkkVRLWSFGYDM-DNAKArc-----wYESRMPIY 381 Methanospirillu...
Q314I1       320 YHQWLGLLyg--plGSKNKtl-vaAQCIRQFrell---------pasaVRVRAFGYDM-DNMKArq-----wCEGEMPLY 381 Desulfovibrio d...
Q054L1       325 YHYWQTIAlg---kEQEDQa----ALVIRRFlnrki--------pgeqTSILTFGYDM-DNMKArc-----wYESEIPFF 383 Leptospira borg...
YP_001234934 311 YRNWIGLVlr--spDGLRRp----APIVSTWrndryrg----teeakgARLIAGGYDT-DNMKArg-----fMETEVPLV 374 Acidiphilium cr...
Q2RY16       332 YGDWLAIWg----yDGTPAv---gVEIWDRRrallg-------atlagDAIEAFGFDM-DNAKArq-----wLDIRLPWV 391 Rhodospirillum ...
Q0BSC4       310 YRNWLGVVv----kEKGSDl----SELALCLredr----------iggGSILVAGWSM-DNMKPrd----fiLSRQRRLS 366 Granulibacter b...
Q74DD1       308 WTHLSRFVvqrqttNSKEEgq-epAAVVRQAqgl-----------lnkLRLAVGGYRN-NQASI--------LERRHELI 366 Geobacter sulfu...
ZP_01313573  307 WTQLGSFVfardvvDAKTPgq-qpAAVIKQAqelg----------lrrLALTVGGYRN-NQASI--------LERRHELL 366 Desulfuromonas ...
Q1GAI7       425 VLfdetedrknaWPQRIEEMVDLNQEVGRKYYGFLMEVGRirfgpqgaADFAGRNSq--------------tFYDNLNEP 490 Lactobacillus d...
Q12YB1       385 NVadel---rqsYEQIVSRLVKTAEIIAYNTRSCVKKALFg------dNTPRGDLSfid-----------srFWHDTESE 444 Methanococcoide...
Q2FNL5       382 LLddek--krelFENIVSNLIFTAEYVLQSLAGSIKDAISg-------HGNKGKEPvdl----------rsrFWNETEEL 442 Methanospirillu...
Q314I1       382 ALdpae---taiLQNEIELWLDAADKTRSNLIKALKQALFad----ggRNAKADQTllan--------astaFWSRTESA 446 Desulfovibrio d...
Q054L1       384 NIpsdk---iekFEEQVSQILNASTEVKKNLRQAVRNAWLdk-----kNDSKGDLTfld-----------vsFLKDTENS 444 Leptospira borg...
YP_001234934 375 LAsske--vqerLDALATSLVRASERASYQLRKAVQQALYhp-----gAKVKATAHgial--------lgdrVWLETESA 439 Acidiphilium cr...
Q2RY16       392 GVyged---aatLRTAIAQMIGATQKASQRLRLAIRLALWgqra-tdpKTGKPGFRlpdelpadaatidvtpIWQETEGP 467 Rhodospirillum ...
Q0BSC4       367 AIpa-------eAEYRIVDLIQAADAVAVALRNALTPVLAg-------GEAREAERe--------------eFFRQTETK 418 Granulibacter b...
Q74DD1       367 FLndg----wsgHTEVVHALVGQAVGYRDALNKALFVFSTg------fKEIKGAGVkvhel-------akeqFYRRSEDT 429 Geobacter sulfu...
ZP_01313573  367 SLgqg----wnkHPKTVQEIVDKALGYRDALNKALLTFFKgm----nnKEIKGAGVavhea-------gkeqFYRRSEGI 431 Desulfuromonas ...
Q1GAI7       491 FENWLANLsggdd----------rdkqQELWKKQLRQIALRTLD 524 Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842
Q12YB1       445 FYNILNQLtdvvnde------amvlelKMKWHKELSRISEKLFD 482 Methanococcoides burtonii DSM 6242
Q2FNL5       443 FYATLDRLffslgnv------eqidqiKREWYRMLVGHSVLLFD 480 Methanospirillum hungatei JF-1
Q314I1       447 FYSLAARFvesvqqqddaqqialakmlRNEWANRILAATDAIFS 490 Desulfovibrio desulfuricans subsp. desulfuricans st...
Q054L1       445 FYDLIRNVqenlisd-----vadfaalKETWLKLLNESACKLFD 483 Leptospira borgpetersenii serovar Hardjo-bovis L550
YP_001234934 440 FFSALDRAmsldd----------tapeRVAWQVRLRGLALRIFD 473 Acidiphilium cryptum JF-5
Q2RY16       468 FRRHVQDLiakpd---------ghlavRKLWLKTLRGQTLRQFD 502 Rhodospirillum rubrum ATCC 11170
Q0BSC4       419 FLTHVQAIerg-------------edpAEAWLADLRRQALGQFD 449 Granulibacter bethesdensis CGDNIH1
Q74DD1       430 VLDTLARIdfeq-----------aalaLLAMGDGLHGIVVGLFN 462 Geobacter sulfurreducens
ZP_01313573  432 ILDALASVdfen-----------pketLLTLGEVLHRLDRELFE 464 Desulfuromonas acetoxidans DSM 684
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