4IF2,4H9U,3PNZ


Conserved Protein Domain Family
Php

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COG1735: Php 
Predicted metal-dependent hydrolase, phosphotriesterase family [General function prediction only]
Statistics
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PSSM-Id: 441341
Aligned: 120 rows
Threshold Bit Score: 236.222
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4IF2_A         1 MPELNTARGPIDTADLGVTLMHEHVFIMTTEIAQNYpeaWGDEDKRVAGAIARLGELKARGVDTIVDLTVIG-LGRYIPR 79 
WP_011652630   1 MKHLRTTLGPKSKSELGMILPHEHVFVDLRTPDQPGy-aEAEIEDVVRLMAPEIERIKKLGVTALVECSTGG-VGRRADI 78 
WP_012084873  11 ARHLHTTLGPLGAGDVGLVLPHEHLLVDFRPADSPGf-aQADPAEFASVVEPLLAGAAAAGVTALVECTPPG-LGRRVDL 88 
WP_015754427   3 LGQLITVTGEIHPEDMGVSLIHEHVLVDWIGADSTGy-hRWDREAVVARALPYLEELRQYGVRTFLDCTPAY-LGRDPWI 80 
WP_013285143   1 MGYVQTVLGPVPPESLGRVLSHEHLGALVPGPWLSG----GAGDDRADLAAGAVSGLPELGFGTVVDLSPYEvVGHDVTL 76 
WP_041454470   1 MPVLHTTLGALSAPPEGIILPHEHIFVDLRPLDAPNh-gQAKTEDVVALMAPELKRARAAGIAALVECTPEG-VGRHVEH 78 
WP_014434702   2 TQQLWTTQGPLRKEELGLILPHEHIFVDLGPIEAESy-rRARAEEVIAVMVPHLQAARAAGVTALVECTPVG-VGRRVDI 79 
WP_020446750   1 MPELHTTLGALDREAIDLILPHEHVFTDLGPMEERAh-eTADLEEVVEVVGPEIERAKEAGVTGIVEPTPRG-VGRRVDA 78 
WP_008525945  14 VSHLITTQGTFERDEIDLLLAHEHVFVDLGPMADENw-kDAQAEAVIDRIGPEIERAIDAGIDALVECTPEG-VGRRVDI 91 
WP_055047178   1 MKLLHTTLGPKRADELGMILPHEHVFVDLRTPDQPGy-aQADPAEVVRVMAPEIEAIKARGITALVECSTGG-VGLRVDI 78 
4IF2_A        80 IARVAAATELNIVVATGLY---TYNDVPFYFHylgpgaqLDGPEIMTDMFVRDIEHGIADTGIKAGIL-XCATDep---g 152
WP_011652630  79 DLAVSLATDFPIVVPTGNY---REPWIPEWIG-------HASEKELEAWMLRELTEQIDETGFQAGWI-KLSAGdd---g 144
WP_012084873  89 VLDVSRRTGVPVVVATGVY---REPWVPDWVY-------GASDDELEAWMHRELTEGVDGSGVLAGFI-KISAAed---g 154
WP_015754427  81 LRALSEQTGIQILTNTGYYgarDNLHVPESAR-------EATPREIAAVWIEEFREGIDGSGIRPGFI-KISVAnr--dt 150
WP_013285143  77 LREVALRTGLHVVAGSAIY---LEPYSPGWAL-------SASVDEMRERFVADATIGVGDTGIKVGIFgEQATGln---e 143
WP_041454470  79 VLAVSQAGNFPILVPTGIY---REPWVPAWAH-------HADEGILQSWMMGDLEVGVGNTGVRAAFI-KLSMGdd---g 144
WP_014434702  80 VKAVADAAAFPVVVATGVY---REPWVPEWVH-------AASEEELAAWMVRELCEGVEETGVRAAWI-KLSAGde---g 145
WP_020446750  79 VEAVSEATDFPIAVATGIY---QEPRIPEWAR-------EAGEDELTEWMIEELTEGVEEAETQAAFI-KVSTDdddpea 147
WP_008525945  92 DLAVSEATDFPIVVPTGIY---QEPNIPQWAR-------DMSVEDLTDWMLAELTEGIDDTGVRAAWI-KVSTDdddpeg 160
WP_055047178  79 DLAVSRATGFPIVVPTGNY---REPWIPNWVR-------DATEAELEVRMYRDLSEGVGDTGVKAAWI-KVSAGdd---g 144
4IF2_A       153 LTPGVERVLRAVAQAHKRTGAPISTHTHAGlRRGLDQQRIFAEEGVDLSRVVIGHCGDSTDVGYLEELIAAGSYLGMDRF 232
WP_011652630 145 MTALETKILRAAARAAVQTDAVIGSHTIRG-RVVMDQLDVIEAEGYRADRFISIHTQEEQDFALNVAVADRGAWIEYDHV 223
WP_012084873 155 IRPVEERVVRAAARAAARTGALVGSHTTNG-DVVLGQIDLAVAEGLAPDRFLSIHTQTITDPALRQAIVDRGAWIEFDDV 233
WP_015754427 151 LSALHEKIVRAAAYTHLETGMAIVSHTGGD-GPAMAQIGILREMGVSPEAFTWTHAQNG-TPEGYQEAARAGAWISLDHL 228
WP_013285143 144 ITPHEEKCLRAAARAHVATGLAVNTHTTHG-TMALEQVEILREEKADLSRVVIGHLDINPDPDYLRAVLATGVNIAFDTL 222
WP_041454470 145 ITPVERKILRAAARAGAKTGAAIGSHTIRG-RVVLEQIDELEACGFDPHRFISIHAQAEPDFALNLEVAHRGAWIEYDGI 223
WP_014434702 146 ITPVEAKILRAAARAGQVTGALIGSHTIRG-RVVREQLDIIEEAGYRPQRFLWIHTQAEPDFDLHLEMARRGCWLEYDAI 224
WP_020446750 148 LSDDEETILRAAARAGAETGAAIGSHTLYA-DMVETQLDVIEDAGYTADRFVWIHAQAEDDLDRHVEIAERGAWIEYDWI 226
WP_008525945 161 LSPDEEKILRAAARAGAETGAVIGSHTLHG-DVVDQQLDIIKAEGYDPSRFIWIHAQAEADRDSHERAAERGAFVEYDWI 239
WP_055047178 145 ITPLEAKILRAAARAAQRTGAVIGSHTIRG-RVVMDQLDIIEAEGYRADRFISIHTQEEHDFGLNIAVAQRGAWIEYDHV 223
4IF2_A       233 GVD----------------------VISPF----------QDRVNIVARMCERGHADKMVLSHDACcyfdalpEELVPVA 280
WP_011652630 224 GR-------------------------AGD----------NEVAELVIKALEAGCGDRLLLSHDRG-------WFDPAQP 261
WP_012084873 234 GQG-------------------------DD----------TRTLELVLGSLEAGQAGQVLLSHDAG-------WFDPALP 271
WP_015754427 229 NAG-----------------------TKGRqanpgnpgnlDWYVQTLSELKRRGLLDHVLLSHDAG-------WYDVGEP 278
WP_013285143 223 GKQfwdfvlaplpadppegefakraYHRPD----------RARLGMLAGLVRDGYADRILLSMDLTg------AEAYLNP 286
WP_041454470 224 GWS-------------------------ED----------EAYIRRILDMLEAGFEGQILLSMDRG-------WYDCAQP 261
WP_014434702 225 GSD-----------------------RFSD----------EWFIERIHRLLDAGFGEQLLLSHDRG-------WYDPSKP 264
WP_020446750 227 GGD-----------------------DQPD----------AAYVERIERLLAADLGDQLLLSQDRG-------WYDPSEP 266
WP_008525945 240 GGD-----------------------DQDD----------QTYIDLVAHMTERGYTDRVLLSQDRG-------YYDPSEP 279
WP_055047178 224 GR-------------------------APD----------AAVSELILRALDADLGSQLLLSHDRG-------WYDPAIP 261
4IF2_A       281 --MP--NWHYLHIHNDVIPALKQHGVTDEQLHTMLVDNPRRIFE 320
WP_011652630 262 --MGgiPKPYTHLSTVLLPELKRRGIDDGTLMRLTHDNPFEAFA 303
WP_012084873 272 --GGgtPRPFTDLTGSFLPALRAAGVDADVVDDLCVRNPFRAFA 313
WP_015754427 279 --NGggYRGYTDLFTHLIPRLQENGFTRGEIDQLLKDNPRRAYA 320
WP_013285143 287 gtHG--RLGYSYLGREIVPGLARLGVPPEAIDQMLTANPARLLT 328
WP_041454470 262 --GGgtPHPFTYLVEVFLPKLRAAGVDEATLRRLTVENPFRAFA 303
WP_014434702 265 --NGgaQLPYTYLSEVFLPKLRASGVDEATVRQLTEQNPWRAFA 306
WP_020446750 267 --RGgeVKPYTYLTDEFLPALREAGIDEATIRQLTEDNPFDAFA 308
WP_008525945 280 --DGgdIDPYTYIVESFLPKLRASSVDDAAIETIVHENPFDAYS 321
WP_055047178 262 --GGgtPTPYTHLSDVMLPLLQAKGVDADTIRLLTVTNPFAAFA 303
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