2IAY


Conserved Protein Domain Family
DUF1831

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pfam08866: DUF1831 
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Putative amino acid metabolism
Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.
Statistics
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PSSM-Id: 430273
Aligned: 27 rows
Threshold Bit Score: 143.886
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2IAY_A         3 AYTTTVKLDGDTKTYTLSPTVKKYTLXDLGFVKGRSGAFSFERSLDPTSPYQAAFKLKXTVNADLTGFKXTTVTGNGVQR 82  Lactiplantibaci...
WP_011953428   2 EFTKTVQISGDKDKYTISPEIKKYALLDLGFEQTNRGNFEYLGSLDTDNPFKPVARLRILINSDLDGFKMETLSGNGLRK 81  Limosilactobaci...
Q74JX0         1 -mANTVIINGDNRKFTINPEIKRYALIDAGFTKTKRGNFMYKHPLYNESPYNATCQLKLTINEDLDHLTMVVTDTNGLQK 79  Lactobacillus j...
Q5FKU1         1 -mANTVVINGDKRKFTLNAELKLYALIDAGFVKTAKGNFNYEHPLYNDSPYNAPTKLKITINKALDHWTMVVTDRSGLQK 79  Lactobacillus a...
Q1GAS2         1 -mANTVMINGDKRKFMLNTDVKLYALIDAGFQKTPRGNFVYEHPLYNESPYNATTKLKMTIKSDLTSLTMVVTDPSGLKK 79  Lactobacillus d...
WP_013989783   2 AFTKEVTILGDDITYEINPTLKKYALTDVGFVKSNAGTYVMQRALQPDKGLENSVKLKVAINGSVDGFKMKVVNASGNTN 81  Weissella koree...
CCO10826       2 AFETTASLVGSTEKYRLTPNVKKFTLRDNGFEETSSGNYQFIRPLDGSPENKQGIKLKIIVNKDLKTFKMSTTTSNGLRA 81 
WP_014125500   2 AFQEVTTILGAQTSYKLAPTAKKYTLRDNGFSETSSGNFQLIRPLEATPQSKEGLKLKITVDKDIQKMKMSVTTANGLKA 81  Tetragenococcus...
BAK21328       2 TFAKTATIEGGTTTYTLHPQIKRYTLKDNGFVETPSRNFQFIRSLEATPQNRDGFKLKIVISKDLKTLKMSVTTANGLKA 81 
Q832Z7         2 AFTTTAAVEGSTVFYKVHPSAKRYTLKDNGFTETKSGNFQLIRSLDPTPQRNEGFKLKITITADLKELKMSITTANGLKP 81  Enterococcus fa...
2IAY_A        83 ANIFKNDAHPEAVEQLRYILANFIERDILT 112 Lactiplantibacillus plantarum
WP_011953428  82 INIFNHQRAAEFIQQYHYILDEMVARQIFT 111 Limosilactobacillus reuteri
Q74JX0        80 VNIFKNKQLAPMVELLNFILKDLEDRQIIA 109 Lactobacillus johnsonii
Q5FKU1        80 VNIFKNKQLAPTVELLDYILKDLEERKIIA 109 Lactobacillus acidophilus
Q1GAS2        80 VNIFKNKQLAPTVELLDYILKDLEERKILS 109 Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002
WP_013989783  82 INIFKSNNQSDLVELLRYYLDELVSREIIK 111 Weissella koreensis
CCO10826      82 VNIYTNENFKMSVDKFKFIMDGFIERGVME 111
WP_014125500  82 VNIFKMKN-ELLQEKFYFLMDGFIDRGLFE 110 Tetragenococcus halophilus
BAK21328      82 VNIFKNDQHKASQEKLNFLIETLMNNHILV 111
Q832Z7        82 MNIFKNEQHEMSKEKYFFLMDGLISRGVLE 111 Enterococcus faecalis
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