Conserved Protein Domain Family
PRK09427

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PRK09427: PRK09427 
bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF
Links
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Statistics
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PSSM-Id: 236509
Aligned: 187 rows
Threshold Bit Score: 533.239
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
300859503   5 VPMPTVLEEIVNTRRSHIQEISARISHIN-PLRLPRSTKSLFQALGGSinggaasrrqaysNA----StraphFIMECKS 79 
145297022   4 NNLPTVLESIVEGRRGHLEEIRARIAHVDv-DALPKSTRSLFDSLNQGrg---------------gaR-----FIMECKS 62 
162449371   2 AEQGNVLARIVERKRADVAERERRTPLASlRASAPPTSRSLRRALSAP-------------GA----R-----FVLECKK 59 
38234889    8 RPMPTVLESIVSGRRSHLPEIQARISHVD-PARLLRSTRSLFQSLGGR-------------SDggpaLrgsarFIMECKS 73 
25029427   19 ANMPTVLESIVEGRRGHLEEIRARIAHVDvE-ALPASTRSLYDSLNQGrg---------------gaR-----FIMECKS 77 
23309008    4 NNLPTVLESIVEGRRGHLEEIRARIAHVDv-DALPKSTRSLFDSLNQG-------------RG----Ga---rFIMECKS 62 
227834332   1 MALPTVLEGIVAKRRTHLPAIRERLAHVDlA-ALPRSKRSFYDALNGT-------------NR----------FIMECKS 56 
256822861   1 --MLNVLETILEHKRSVIGNTADYH-------DLEPSQRSFYDALSKP-------------HY----G-----FIMECKK 49 
62391881    4 NNLPTVLESIVEGRRGHLEEIRARIAHVDv-DALPKSTRSLFDSLNQGrg---------------gaR-----FIMECKS 62 
56460855    6 RLEKNVLKTIVERKVEQNKTQAELMPLSEiKSQLRPSDRSLYEALSGE-------------QA----G-----FILECKK 63 
300859503  80 ASPSLGTIRTDYSPGDIARIYSRYASAISVLCEPDKFNGDYDHLATVAASTHLPVLCKDFIVDPVQVQAARYFGADAVLL 159
145297022  63 ASPSLGMIREHYQPGEIARVYSRYASGISVLCEPDRFGGDYDHLATVAATSHLPVLCKDFIIDPVQVHAARYFGADAILL 142
162449371  60 ASPSEGLIRPDFDPHAVAAAYYGVADAVSVLTDEPFFQGSFEILQAVRAVVDVPILCKDFVVTPYQVIEARANGADAILL 139
38234889   74 SSPSLGMIREDYRPGDIARVYSRYAAGISVLCEPDRFGGDYNHLATVAATTHLPVLCKDFIIHPAQVHAARYFGADAILL 153
25029427   78 ASPSLGMIREHYQPGDIARIYSRFASGISVLCEPDRFGGDYDHLATVSASTHLPVLCKDFVIDKVQVHAARYYGADAILL 157
23309008   63 ASPSLGMIREHYQPGEIARVYSRYASGISVLCEPDRFGGDYDHLATVAATSHLPVLCKDFIIDPVQVHAARYFGADAILL 142
227834332  57 ASPSLGLIREHYEPGAIARIYSRYASAISVLCEPDRFGGDYDHMQTVALSTHLPVLCKDFIIDPIQVYAARYFGADAILL 136
256822861  50 ASPSKGLIRAKFDLDQIVPVYDQYADAISVLTEERFFRGSFSNLQKVRKLTDKPLLCKDFILSPKQIRQARYFGADAVLL 129
62391881   63 ASPSLGMIREHYQPGEIARVYSRYASGISVLCEPDRFGGDYDHLATVAATSHLPVLCKDFIIDPVQVHAARYFGADAILL 142
56460855   64 ASPSKGLIRADFDAPQLAKSYQPYAAAISVLTEPEFFQGRLDYLTAVRRQVTQPVLCKDFFIDEEQVYRARYFGADAILL 143
300859503 160 MLSVLDDATYLSLSSEAERLGLDVLTEVINEEEVKRGIRLGAKIFGVNHRNLHDLSIDLSRSSQLEPLIPENAVLVSESG 239
145297022 143 MLSVLDDEEYAALAAEAARFDLDILTEVIDEEEVARAIKLGAKIFGVNHRNLHDLSIDLDRSRRLSKLIPADAVLVSESG 222
162449371 140 MLSVLDDATALLCLGAAEALGMDCLVEVHDEAELERALALPAPVIGINNRDLKTLKVDLAVSERLAPRVPRDRIVIAESG 219
38234889  154 MLSVLDDATYTELSQEAARLGLDVLTEVIDEVEVERAIRLGATIFGINHRNLHDLSIDLNRSARLAQLIPDSAVIVSESG 233
25029427  158 MLSVLDDAAYTELATEAERFGLDVLTEVIDEEEVERAIKLGAKIFGVNHRNLHDLSIDLDRSGRLAKLIPADAVLISESG 237
23309008  143 MLSVLDDEEYAALAAEAARFDLDILTEVIDEEEVARAIKLGAKIFGVNHRNLHDLSIDLDRSRRLSKLIPADAVLVSESG 222
227834332 137 MMSIVDDETYAELKQLADSLGLDVLTEAITEEEVARATAFGIDAIGINNRNLHDLSIDLTRSERLSHHVPSGKVIVSESG 216
256822861 130 MLSVLNDKDYTICQEQAESLNMDVLTEVHTEAELERAIKLGAKIIGINNRNLKDLSTSFEHTQALAKKIPADRLVVTESG 209
62391881  143 MLSVLDDEEYAALAAEAARFDLDILTEVIDEEEVARAIKLGAKIFGVNHRNLHDLSIDLDRSRRLSKLIPADAVLVSESG 222
56460855  144 MLSVLDDAQYIALRDIAESLAMDVLTEVANEEEMKRAAKLDANIIGINHRDLTDLSIEPNRSAQLAPLAPQNALLIAESG 223
300859503 240 IKTNETVRQLAGHSDAFLVGSQLTSHSNIDSASRSLVYGTNKVCGLTTASAAQNARAVGATHGGLIFEDSSPRNVSRETA 319
145297022 223 VRDTETVRQLGGHSNAFLVGSQLTSQENVDLAARELVYGPNKVCGLTSPSAAQTARAAGAVYGGLIFEEASPRNVSRETS 302
162449371 220 VESRAHVERLAPSVDGFLVGTSLMRSPDIADAARALVTGRVKICGLTRPGDAREAERLGARFGGLVFAETSPRRVTREQA 299
38234889  234 IRNNETVRQLSGHSSAFLVGSQLTSQPDVDRAARELVYGLNKVCGLQSPSEAQAARASGAIYGGLIFVESSPRNVSRETS 313
25029427  238 VRDNETVRQLGGHSHGFLVGSQLTGQPDVELAARELVYGTNKVCGLTSPTAAQTARAAGATHGGLIFEEASPRNVSRETS 317
23309008  223 VRDTETVRQLGGHSNAFLVGSQLTSQENVDLAARELVYGPNKVCGLTSPSAAQTARAAGAVYGGLIFEEASPRNVSRETL 302
227834332 217 IRDNQTVRHLGSHANAFLVGSQLTGTPDIDRAARELVYGHNKVCGLTTWSAAQAARAAGAIYGGLIFEEASPRNVSRETA 296
256822861 210 INTHQDVLDLSQFSDACLVGSSLMKEDDLELAARQLVYGDIKVCGVTQQSDADLLQELPASCVGVIFVPNSKRCVD---S 286
62391881  223 VRDTETVRQLGGHSNAFLVGSQLTSQENVDLAARELVYGPNKVCGLTSPSAAQTARAAGAVYGGLIFEEASPRNVSRETL 302
56460855  224 FAEHADIRRVAPFVNGFLIGSALSAQPDVDLACRKLLYGQNKVCGLTRAEDAINARSQGAVFGGLIFVERSPRCVTLKQA 303
300859503 320 EKIIAAEPnLNYVAVSRRDHgWEEIL----LPEITSLQIHApyqgsiAGERALIDNARRELqkagREDVSIWRAVSMT-- 393
145297022 303 QKIIAAEPnLRYVAVSRRTS----GYkdllVDGIFAVQIHAplqgsvEAEKALIAAVREEV----GPQVQVWRAISMSs- 373
162449371 300 EIVVATAAgLPFVGVFLNQS-VDFVAdtarAIGLRAVQLHG------DEDAAFIEALRRAL----PEGCEVWKAVPMAps 368
38234889  314 KKIMAAEPdLTYVAVSRRTTgWTEIIg----gNIAVAQIHSpyqgsiAAEKELINHVRGEV----GDKVKIWRAVSMTh- 384
25029427  318 AKIIAAEPgLRYVAVSRRTSgYGELIq----dGIAAVQIHAplqdsvDAELALVDAVRAEV----GPEVEVWRAVSMTs- 388
23309008  303 QKIIAAEPnLRYVAVSRRTSgYKDLL----VDGIFAVQIHAplqdsvEAEKALIAAVREEV----GPQVQVWRAISMSs- 373
227834332 297 LDIIAHEPdLNYVAVSRRTTgWEDLA----IDGISALQIHApyqgstEAELELIESVRAAV-----GERQVWRAIDMTa- 366
256822861 287 NIITSS---KPLIGVFQDQS-IDEVVsaaqQYRLQAVQLHG------DESLDFAQAIKQQV-----TDIKVSKVFHVGp- 350
62391881  303 QKIIAAEPnLRYVAVSRRTS----GYkdllVDGIFAVQIHAplqdsvEAEKALIAAVREEV----GPQVQVWRAISMSs- 373
56460855  304 KQITTEANgLEYVGVFADQP-LESLIdtakYVGLSAIQLHG------HEDIDYVVQLRQQLrqagLEAVKIWKALAIEsp 376
300859503 394 -----------------LPegaaTATa--lTDDVDMLLLD----A----GIGGTGTSFNWEKITpdiaP--------KAI 438
145297022 374 ----------------pLGaevaAAV----EGDVDKLILD----A----HEGGSGEVFDWATVPaavkA--------KSL 417
162449371 369 geaagaagaagagddgaGAe---------vERSADRLVFDtrtaE----ARGGTGRTFAWSAID----Ghpa---raRSL 428
38234889  385 ----------------aDGslvaEAL----APEVDRLILD----T----GNGGTGTTFDWARIPeavkG--------KTL 428
25029427  389 ----------------eLGpeiaVAL----TDKVNRLVLD----A----HQGGSGESFDWSTIP----Pev----rsSAL 432
23309008  374 ----------------pLGaevaAAV----EGDVDKLILD----A----HEGGSGEVFDWATVPaavkA--------KSL 417
227834332 367 ----------------pHGpalaSAL----ADAVDLLILD----S----ATGGTGTSFDWTSVP----Dev----kaKSL 410
256822861 351 ----------------eISseifEKElktlLDTYDEVLLDtevtNstqnQRGGTGVSFDWSLLR----NlnpqlfsqKLR 410
62391881  374 ----------------pLGaevaAAV----EGDVDKLILD----A----HEGGSGEVFDWATVPaavkA--------KSL 417
56460855  377 ---------------aqLP-----------DLAVDAFVLD----N----RGGGSGKAFNWELLE----Plste-erqRCL 417
300859503 439 LAGGLNLDNLPEALKAGCAGLDLNSGFEYPStagswsGMKDSGLLRQAFSKIRNF 493
145297022 418 LAGGISPDNAAQALAVGCAGLDINSGVEYPAgagtwaGAKDAGALLKIFATISTF 472
162449371 429 LAGGLNPDNIAAARRVGTWGLDVASGVERAP------GEKCADLLVRLFDSARGP 477
38234889  429 LAGGIGPDNVTEALAVGCAGPDLNSGLEYPVeagkwaAHKDATAIHSTFTQIRGF 483
25029427  433 LAGGISPGNAADALSVGCGGLDINSGVEYPAgagewaGAKDAGAILKIFSTIRTF 487
23309008  418 LAGGISPDNAAQALAVGCAGLDINSGVEYPAgagtwaGAKDAGALLKIFATISTF 472
227834332 411 LAGGLKPENLTEALRVGTAGLDINSGVEVNV-------RKDSALIAQAFHIIRHF 458
256822861 411 IAGGVNAENIQNLKQLGVINVDLSSSVESSP------GVKGKDLLAYFFRAARPQ 459
62391881  418 LAGGISPDNAAQALAVGCAGLDINSGVEYPAgagtwaGAKDAGALLKIFATISTF 472
56460855  418 LAGGIGPESISSAIELGFAGVDINSQAEWKP------GIKNSQKVAQTFTKIRHY 466
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