Conserved Protein Domain Family
endonuc_SmrA
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NF033154: endonuc_SmrA 
DNA endonuclease SmrA
YdaL is a small endonuclease with homology to the C-terminal domain found in the endonuclease MutS2, but not found in the related mismatch repair protein MutS. The biological role of this endonuclease is not yet known. As one of two Small MutS2-Related proteins in E. coli, This protein was designated SmrA by Gui, et al. (PMID:21276852). The term SMR is much better known for describing a large family of Small Multidrug Resistance (SMR) efflux transporters, but in that context is used with three capital letters.
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Statistics
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PSSM-Id: 467968
Aligned: 106 rows
Threshold Bit Score: 235.446
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_007230049   4 DEESLFLDEMT-DVAPLKRERrvr-vtPKQNDR--DTSLEQRREAAVldkTRDGNILTEDGlaVTPLDPWYVLEFKRPGI 79  Candidatus Seon...
WP_004959443   4 EEKGFFEQAMA-DVTPLSGRQqtl-ylKADHRE----DQRARRAAQA---LQQENPLSSDL--LEIIPCDVPLEYRGEGI 72  Serratia odorifera
WP_015673499   4 EDKGFFEQAMA-DVIPLSGRQqt---lYLQPQS--QVDKRARRDALA---QSEENPLSSDF--LTIIPGDEPLEYKREGI 72  Serratia sp. FGI94
WP_013575560   5 DD--LFSQEMA-GVQPLASDK------RVVYLKnsVAGHKVSADPES---EMRENPLTTGF--LNIQPCDDPLEYKHDGV 70  Rahnella
WP_016913852   6 RDELDFRSLVG-EVTPLAKRNrad-tgPRRQTP--SEAQLARRESAAq-rFDERNFLSDDF--VDLLPPFDPIEFRREGT 78  Halomonas
WP_010628578   7 EDQD-FRALVG-DVKPLRRSAnra-dpGQRRSRp-SEAQLARRESAQae-lGENNFLSDDF--VELVPPFDPLAFRRDGI 79  Halomonas sp. KM-1
WP_016854934   5 HDDADFQALMG-DVKPLSRGQgrahtgQTRRMP--TEAQLAKRESAAg-dAAGRDILSDDF--VDLVPPFDPLDFRRDGI 78  Halomonas smyrn...
WP_013332365   7 DEMD-FRALVG-EVRPLRGGTgradpgRPRRNP--SDAQLARRESAVa-eSGSSLGLSDDF--VDLVPPFDPLEFRRDGI 79  Halomonas elongata
WP_019017703   6 EQNLDFGSLMGnDVKPLSKGRdkaditATPRSP--SEAQLARRASAEe-eTSSSNFLSDEF--VDLLPEHDPIEFRRNGI 80  Halomonas lutea
WP_019950250   6 CDEQLFYREMA-DVVPLEKGRnra-dtESPQRPp-SEAQLARRASAQd-gEGESNFLSDEF--VELLPPHDPVEFRRDGI 79  Kushneria aurantia

WP_007230049  80 QNGVFRKLKQGRYEAEARLDLHRMTVAIARKELYEFIQETYGLGIRSVMVIHGKGESKAEreRSSILKGCTDHWLRELEI 159 Candidatus Seon...
WP_004959443  73 QQGVLEKLRHGRYAPQASLNLLKRPVESCRQELFRFIVLAQQENLRSLLVVHGRGREDES--HANIVRSYLAKWLAQLEP 150 Serratia odorifera
WP_015673499  73 QQGVLDKLRSGRYAPQASLHLLRRPVEACRQELYRFIMLAEKQNLRSLLIVHGRGRDDES--HANIVRSYVAKWLAQLEQ 150 Serratia sp. FGI94
WP_013575560  71 QQGVLDKLRQGKYPLEASLNLLRKPVEQCRQELFAFFCQAQAENLRTLLIIHGRGREDES--HANIVRSYIAKWLQQLDD 148 Rahnella
WP_016913852  79 QQGVVDKLKHGGYSVQAQLHLLRRPLAECRRMLFPFIQEAYAHDLRSVLIVHGRGRELDS--PANVLRSYIAKWLTQFDE 156 Halomonas
WP_010628578  80 QQGVVDRLRHGGYAAQSRLHLLRRPLAECRRMLPPFIREAYAHDLRSLLIVHGRGQEIDS--PANVLRSYLAKWLVQFDE 157 Halomonas sp. KM-1
WP_016854934  79 QRGVAERLRQGGYPMQASLHLLRRPVEEARQALPAFLREAVEHDLRSVMIVHGRGREIDS--PANVLRSYLAKWLPAFDE 156 Halomonas smyrn...
WP_013332365  80 QRGVVERLRHGGYPAQASLHLLRRPLEECRRALPDFLREAREHDLRSVLIVHGRGREIDS--PSNVLRSYLAKWLAAVDE 157 Halomonas elongata
WP_019017703  81 QTGVLDRLRQGGYPPEARLHLLKQPVRTCRSELFSFIQDAIAHDLRSLLVVHGRGKAVDS--HANVVRSYVAKWLMQFEE 158 Halomonas lutea
WP_019950250  80 QTGVIDRLRDGGYRVDSQLNLLKRPVAECRRELFRFIREAREHDLRCVMLIHGRGKSDDS--HANVVRSYVMRWLSQFDE 157 Kushneria aurantia

WP_007230049 160 VQAFHSAQPRHGGTGAVYVLLRKSEDKKRENREKFMKG 197 Candidatus Seongchinamella marina
WP_004959443 151 VQAFCRALPRDGGDGACYVTLRKSAQAKADNFERHAKR 188 Serratia odorifera
WP_015673499 151 VQAFCRALPRDGGEGACYVTLRKSAAAKADNFERHAKR 188 Serratia sp. FGI94
WP_013575560 149 VQAFCVAVQKDGGAGACYVALKKTAQAKQENWERHAKR 186 Rahnella
WP_016913852 157 VQAYVSAQPSEGGLGATWVMLRKSDRAKAHNRERQQKR 194 Halomonas
WP_010628578 158 VQAFASAQQADGGLGATWVMLRKSERARADNRERQQKR 195 Halomonas sp. KM-1
WP_016854934 157 VQAFASASQADGGLGTTWVMLRKSERARAANRERQQKR 194 Halomonas smyrnensis
WP_013332365 158 VQAFVSAGQGDGGIGATWVMLRKSERTRAANRERQQKR 195 Halomonas elongata
WP_019017703 159 VQAYASAQPAHGGIGATYVMLRKSERARARNREVQQKR 196 Halomonas lutea
WP_019950250 158 VQAFASAQPRHGGIGATYVMLRKSDRARQRNRELHQRR 195 Kushneria aurantia
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