Conserved Protein Domain Family
type_I_sec_HlyB

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TIGR01846: type_I_sec_HlyB 
type I secretion system ABC transporter, HlyB family
Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Statistics
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PSSM-Id: 273831
Aligned: 5 rows
Threshold Bit Score: 1103.65
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P10089        10 GLYALEILAQYHNVSVNPEEIKHRFDTDG-TGLGLTsWLLAAKSLELKVKQVKKTIDRLNFISLPALVWR--EDGcHFIL 86  Escherichia coli
AAC44070      30 GLVALSLLLGVHNIAVTPEQLRHMLGHAEgASVDDL-ILLAKRQQGVRAKAVDVPRGGLARQPLPAIADG--PEG-WFVI 105 Sphingomonas sp...
WP_011713619  20 GLLCVMLLARFHQIPSSRDGLRHEHGQPG-ESFGHLeVLKALKALGLKAKAVKSAKKRLNKLPLPAIIPSakEGG-FQIL 97  Magnetococcus m...
WP_002210593  18 PLEALACAATCFDLTIEASQLAHQLGLAP-DEIDSIaLCRCAAWIGLRARKVNQSFERVGKLVLPVLFSD--GAQ-WYVL 93  Yersinia pestis
WP_001069565  27 GIEAVVYAGQQFHKKSTSSQLKHALGVSY-ANLTDMeMREAADYLGLKSQITKLSIQAFNTLPLPALIEY--QGG-WKVM 102 Vibrio cholerae
P10089        87 TKVSkeANRYLIFDlEQRNPRVLEQSEFEALYQGHIILIASRsSVTG-KLAKFDFTWFIPAIIKYRKIFIETLVVSVFLQ 165 Escherichia coli
AAC44070     106 GGLT--EHGVIIQR-PGHAPEQVDREGLDALWSGTLVLLTTR-AVAG-QALRFGFSWFAAQFQRYRRLFLEVLGITLALN 180 Sphingomonas sp...
WP_011713619  98 AKAE--GGKVLLHDpTEAKPEVMDTEVFLEQWDGSVILAATR-GKDP-TGGKFDITWFIPAVIRYRKLFSEVLYASFFLQ 173 Magnetococcus m...
WP_002210593  94 LSLT--AQEATVYFaGSDQTRKISPEVLAKLWRNEVILLAKA-EPITaKKQFFGFSWFIPVVMKSRHQLRNIILISLLLQ 170 Yersinia pestis
WP_001069565 103 IQTD--DNGWTAYDpATDSLHTLSFTSAESTAHYKVMLIADE-SLSV-KEVKFGLSWFAPSILRQKSQLRDVFLYAIALQ 178 Vibrio cholerae
P10089       166 LFALITPLFFQVVMDKVLVHRGFSTLNVITVALSVVVVFEIILSGLRTYIFAHSTSRIDVELGAKLFRHLLALPISYFES 245 Escherichia coli
AAC44070     181 LLGLAAPLLFQSVIDKVLVHNSMSTLSVLAFAFLAVSVWEVALGWIRTRLFTETTQKIDVELGARLFHHLLALPLGYFEK 260 Sphingomonas sp...
WP_011713619 174 VFALISPLFFQVIIDKVLVHRGLTTLDVLALGMLVVALFEMFLGGLRTYLLSHTTNRIDVELGAKLYRHLMNLPMSFFGS 253 Magnetococcus m...
WP_002210593 171 AILLVTPMLFETVIDKVLVSRGVDSLVVLGGAMVALAITEPGYTLLRSWLFAHLSSRVGAELNTQLYRHLLGLPLGYFTG 250 Yersinia pestis
WP_001069565 179 IFALVSPMLFENVIDKVLVGRSLSSLHVLALAMLALAIAEPAYSYLRNTVFGHLASQVNAELSGRLYRHLVGLPLTYFKQ 258 Vibrio cholerae
P10089       246 RRVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILFSLPCYAAWSVFISPILRRRLDDKFSR 325 Escherichia coli
AAC44070     261 RRVGDTVTRVRQLETIREFLTNASLTVMVDPLFTVVFLGAMLFYSPMLFGVVIVSLVAYAMVSFGVAGPLRTRVEDKFEK 340 Sphingomonas sp...
WP_011713619 254 RRVGDSVARVRELENIRNFITGSAMTVAIDIPFTFVFVAVMFWYSPTLTYVVVGAIPFYILLSVFVSPILRKRVEEKFAR 333 Magnetococcus m...
WP_002210593 251 QQTGQTIAKMREMEQIRSFLTGSALTMVLDLFFVVTFIAVMFRYSGQLTGIVLISLLCYLLFWSAVGGRLRKRVAQQYET 330 Yersinia pestis
WP_001069565 259 RQTGQIIARVREMAQIRQFLTGSTLMLLLDLIFVTVFLAVMFHYASTLTWLVIGSLVIYFVLWLIAGPLIRKKVESEYES 338 Vibrio cholerae
P10089       326 NADNQSFLVESVTAINTIKAMAVSPQMTNIWDKQLAGYVAAGFKVTVLATIGQQGIQLIQKTVMIINLWLGAHLVISGDL 405 Escherichia coli
AAC44070     341 SSASNALLVESVSGIHTIKATAVEPHWQNRWERQLAAYTASSQRLINVANTGSQAIELISKLSFAAILFFGAKAVIGGAM 420 Sphingomonas sp...
WP_011713619 334 GAENQSFLVESVTGVQTVKASALEPQMGRRWDEQLAAYVHTSFRVTNLGNWASQIAGLINKITTLLILWFGAHLVIDGSL 413 Magnetococcus m...
WP_002210593 331 SAQATSFLTEAVSGGETIKTSATESQFNRRWRQVLARYVRASFGSSQAGNLAGQGISLINKITSAILLWFGVTLVLAGKL 410 Yersinia pestis
WP_001069565 339 DANATTFLTEAVTGIETIKTTATEHRFLEQWQRILSQQLNRSFDAQKSGLIAGQAIALVQKLTAALLLWWGVSAVLKGEI 418 Vibrio cholerae
P10089       406 SIGQLIAFNMLAGQIVAPVIRLAQIWQDFQQVGISVTRLGDVLNSPTESYH--GKLALPEINGDITFRNIRFRYKPDSPV 483 Escherichia coli
AAC44070     421 SVGALVAFNMFAQRVSGPVIRMAQLWQDFQQVRIAIERLGDVLNHPVEPRPa-SAATLPVLRGAIRFENVTFRYAEDQPP 499 Sphingomonas sp...
WP_011713619 414 TVGQLVAINMLSGRVSGPILRLVQLWQDYQQAGVSIRRLGDILNTPSEATSdpSRAALPNLKGRVTLERINFRYDPESPE 493 Magnetococcus m...
WP_002210593 411 SPGELVAFNMFAGYVTQPILRLAQAWQDFQHTQIALERIGTILDSPTEPGSa-GLVANCKRAGSLSFKQVRFRYRPDTAE 489 Yersinia pestis
WP_001069565 419 TPGQLVAFNMLAGHVTQPVLRLAQIWQDFQHTLIALRRVGDILDEPRENSKq-GLASVPELDGGIEFSNIRFRYHQDAPE 497 Vibrio cholerae
P10089       484 ILDNINLSIKQGEVIGIVGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIIDNI 563 Escherichia coli
AAC44070     500 VLSDITLDIPAGTSLGIVGSSGSGKSTLAKLLQRLNTPDLGRVLVDEVDVAQLDPAWLRRQIGVVLQENLLFSRSIRENI 579 Sphingomonas sp...
WP_011713619 494 VIRELSLDIRPGEVIGIVGPSGSGKSTVTKLVQRLYTPERGRVLVDGVDLGQVDPAWLRRQVGVVLQENFLFKRSVRENI 573 Magnetococcus m...
WP_002210593 490 VLQNLNLEIAGGEFIGITGPSGCGKSTLTKLMQRLYTPQHGQILVDGQDLAITDPTTLRRQMSVVLQESVLFSGSIRDNI 569 Yersinia pestis
WP_001069565 498 VLANLSLKIKPGQFIGVTGPSGSGKSTLTRLLQRLYVPQHGQVLVDGMDLAIADPVSLRRNMSVVLQESILFSGSVADNI 577 Vibrio cholerae
P10089       564 SLANPGMSVEKVIYAAKLAGAHDFISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHV 643 Escherichia coli
AAC44070     580 ALSNPAMPFEHVVAAATLAGAHDFILRQPRGYDTEIVERGVNLSGGQRQRLAIARALVGNPRILVFDEATSALDAESEEL 659 Sphingomonas sp...
WP_011713619 574 AIGDPGIPMERVIAAAKLAGAEEFISELKQGYETELDEHGGNLSGGQRQRIAIARALVSDPRILIFDEATSALDYESEKI 653 Magnetococcus m...
WP_002210593 570 CQCRPNADEAHVIHIARLAGAHDFIIALPQGYQTQVGEKGGLLSGGQCQRIALARALMADPKILILDEATSALDYESEAA 649 Yersinia pestis
WP_001069565 578 RLCKPQASDEEIRHAAQLAGALAFIEGLPHGFNQPVGEKGAALSGGQRQRIALARALLVNPRILLLDEATSALDYNSEAS 657 Vibrio cholerae
P10089       644 IMRNMHKICKGRTVIIIAHRLSTVKNADRIIVMEKGKIVEQGKHKELLSEpeSLYSYLYQLQSD 707 Escherichia coli
AAC44070     660 IQNNLRAISAGRTLVIIAHRLSAVRACDRIITLEQGRIVESGRHDELLRLg-GRYADLHRRQSG 722 Sphingomonas sp. S88
WP_011713619 654 IQENMRSICQGRTVIIIAHRLSAVRGCNRIMVMDKGVIMEEGGYAELLQKk-GWFARMHYHQSG 716 Magnetococcus marinus
WP_002210593 650 IMRQLPEITRNRTVICIAHRLNTLRQCHRILLLKDGQIAEQGSHEVLVASg-GNYARLWQQQTE 712 Yersinia pestis
WP_001069565 658 IMSNMDEICRGRTVISIAHRLNTIRHADNIFVLDKGQVAESGTHEELLAQq-GLYAKLWTQQVG 720 Vibrio cholerae
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