Conserved Protein Domain Family
HEPN_Apea

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pfam18739: HEPN_Apea 
Apea-like HEPN
Apea-like HEPN nuclease. In epsilonproteobacteria embedded in R-M operons.
Statistics
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PSSM-Id: 436704
Aligned: 121 rows
Threshold Bit Score: 33.1755
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_069957778       16 DMPENERLRIHRALSWYGR---AER-S------------EDD-KDAa----------ILFFWIA-FNSAygfeqdfggks 67  Magnetovib...
adrc:B739_0960    146 RYLAKFF-TQKVGLDWWKQ---AVP-Dkviekt-klrqdNETv--------------FSKIVETdMTLIdfndlgei--- 202
WP_045458391      130 KLLTKFS-VTKLGSKWIDE---NIP-Eeikssv-kkkekEMF-SNEadylyqtdfkdLTTFLSGkIKTPdikelheninn 202 Sporocytop...
WP_044055461      133 RKFITFFMIAKVGKDWVSDnlpSQV-KsalkktkprkysSEL-QKLd----------FKDLGFIlFDTYqladntslynk 200 Alteromona...
WP_036188487      129 KLYSKFA-LIKLGPQWV-D---SIP-DnvavsgnkngvnGSN-PLY-----------DMDFITI-NDLLfkehplkeitp 189 Marinobact...
ACS93557          124 KLITKFM-LTNVGLGWIKE---TVP-Edlkk-----sarAEN-VDL-----------NTNYLYE-TDFIqlsnflfdeyr 180
WP_068997914      135 KLITKFM-LTTVGLGWTKE---TVP-Eelkr-----ssrTEN-IDT-----------NINYLYE-TDFIqlsnflfdeyr 191 Terasakiis...
MPITM:COCOR_04665 130 QLIANFM-LITLGREWAKE---TSP-N------------DFE-ETLrkskr--kdqgHLNILHS-VDFIdlgdflftpys 188
WP_076342949      131 RQLIANFMLVTVGREWAIE---TLPkAved-------avRNSkQKD-----------YLNVLYT-VDFIhlgeflftays 188 Paludispha...
WP_092476139      129 RKIIYIFMIRNSGSKWVER---NIP-RdvkesikktqekNNI-HNM-----------LEDCLYC-ADFIqlgyfffekyp 191 Desulfalla...
WP_069957778       68 ge----kavfneffekiigYDR-Sd------IIYNAIwdkfsdsIRMLmrNKYi-------FQpfwh---fhnGIVGfen 126 Magnetovib...
adrc:B739_0960    203 ------------iykhklgFNKpEn------LTDKI--------LSINseEELqklkqdldGNynrffkqhfkDFNF--- 253
WP_045458391      203 --------------------askiedldlnhLKSFI--------PTNNwnKYF--------SKvvk-----ieWKDF--- 238 Sporocytop...
WP_044055461      201 --------iksykssdeilLSD---------LKNFI--------PRSNwdHFF--------SEqve-----ieGPTL--- 239 Alteromona...
WP_036188487      190 ----------dilkklktgdiSpEe------IEPYI--------PTSNwvRHF--------SDlvd-----ceSNYL--- 229 Marinobact...
ACS93557          181 --------tldisglvkkiSEVnAetvsikeISEFI--------PKSNweRYF--------QSyvd-----ceASYL--- 228
WP_068997914      192 --------tldiaalikkiSEIeTdsvrvdeIHDFI--------PRSNweRYF--------RSnvd-----ceGSYL--- 239 Terasakiis...
MPITM:COCOR_04665 189 --------krtiqdlyiniDKAkEpsd-lanLKEFI--------PQSNwkRYF--------SAlvd-----ceDSYL--- 235
WP_076342949      189 kkt--pqdmyaklkdvkseDDAkA-------LQEFI--------PESNwkRYF--------GEfvt-----ceDGYL--- 235 Paludispha...
WP_092476139      192 inrdwrslimelkkakqldNDSiDk------MIEKYV-------STSNweRYF--------AGei-------qVDEL--- 240 Desulfalla...
WP_069957778      127 weerfqkdiaranqylvsKNAKkilsllfDRLYVLRNQLVHGGATWnssvnRQQINDGHK 186 Magnetovibrio blakemorei
adrc:B739_0960    254 ------------------EKKW-------KQLFQLRNKVAHNNLFT-----KSDLDLASE 283
WP_045458391      239 ------------------ETKW-------LNLYKLRCKVAHNNFIN-----KNDYNEIVQ 268 Sporocytophaga myxococcoides
WP_044055461      240 ------------------KSKW-------ERLYELRNSVAHTSYLS-----SDKYEEIRD 269 Alteromonas australica
WP_036188487      230 ------------------ETRW-------KKLYELRNKIAHNKQFT-----KPDLEDVKK 259 Marinobacterium sp. AK27
ACS93557          229 ------------------KSRW-------GKLYKLRCKIAHNNTFT-----KPDHEQTTK 258
WP_068997914      240 ------------------KVRW-------EKLYKLRCKIAHNNTFT-----KPDYEQTEK 269 Terasakiispira papahanaumokuak...
MPITM:COCOR_04665 236 ------------------DSRW-------KELYEIRCKVAHNASIS-----RSDHSRAAH 265
WP_076342949      236 ------------------KARW-------ERLYDLRCKVAHNALMT-----RSDLGDIEK 265 Paludisphaera borealis
WP_092476139      241 ------------------LDKW-------QILYEFRNKVAHNKKIQ-----KKDFTDAIK 270 Desulfallas arcticus
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