Conserved Protein Domain Family
SphA

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COG4313: SphA 
Sphingosine uptake channel SphA-related outer membrane channel [Cell wall/membrane/envelope biogenesis]
Statistics
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PSSM-Id: 443454
Aligned: 131 rows
Threshold Bit Score: 118.496
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_109037413   1 MDRHskqfgfnvaapFRAA--TLAM-ALa-AATS-AQAADNGLQRYSPGVGGSDMSSPVVPGWY-GQVALVSYHASKLKg 74 
WP_011686765   1 MQPArrtk----phlLWSL--AAIY-PLi-AGHP-AQAQNRGV--YPLGMSAINSGVTPEPGLT-YSNQLLFYVRDQAKd 68 
WP_012023232   1 MKAiikq-----rqnLKSI--FLLF-FFf-VCFL-GNAQLKGG--HILGAMGLQSGTQTPANTLsVYVPGYLYDASSLRd 68 
WP_012839079   1 MNHKi---------------aSAAL-ALl--GTL-AATAVQAEGHYVPGVEGMQGPSVPPPGMY-YLGYIVNYNINDFRa 60 
WP_013258473   1 MINai---------kKMAL--GVAA-AAl--VLA-ASGAAMAFGHYTPGALGLGAATLPPPGFH-YTIYNIFYNADTMId 64 
WP_013721222   1 MKTTsi-------------aaAAAA-AAl--ALL-AATGAHADGHYVPGVEGIQAASVPPPGMY-YLGYLVNYNIDDFRa 62 
WP_083829479  26 MTCshvq----tafgRRQAlaPLVV-TLl-LTAPtALAVT---GHYVPGVEGVKGASVPPAGTY-YRGYAVHYDIEQLNd 95 
WP_014956256   1 MTKNwt--------------vSLTItGMl-LLML-TCAMPAWAGHYTPGTEGAMGASVPPPGFH-YKQYNIYVDSDTLKd 63 
WP_060688242   1 MKQEndkt---mrtfTIII--GLII-ALv-SVSK-AQGLET--GHYGYAINGMRSAHAPAPGFS-LTNISHIYNASQVRm 69 
WP_119334170   1 MRKAsk--------------lAFAV-SCmtMAMS-GIAHAG--GHYVPGVEGIQAASVPPPGKY-YLGYLVNYNIDKIDg 61 
WP_109037413  75 -nDGEAAraalptnaavtyQADIHADARAALTRLTYISTERIWGGNLGFTVMIPLVQRKADLSVsnfnfptgtpgpirag 153
WP_011686765  69 -dNGGTL------------PITGSNTVVMDMNTLTWVSTKRILGARYSASATLPFAKNDLTSDIe--------------- 120
WP_012023232  69 -aNGDKS------------IANPDITMFLTGAGANYVSDFKILGANYGATILVAFASNTIQGNT---------------- 119
WP_012839079  61 pgSSDNL------------PGHNRGTVTALANRFVWITNYKLLGADYGMEAIVPVMRTSLTVNA---------------- 112
WP_013258473  65 -dNGNES------------NVGLDLNVFASAHQFTYMTDYKFLGAEFGFDMIVPLVSTNIEIRA---------------- 115
WP_013721222  63 pgSSTNL------------PGHNSGTVTALANRFVWITGHKLLGADYGVEAIVPLVRTSLTINA---------------- 114
WP_083829479  96 -dNGQAL------------PDSNTGSVTALANRVIHITDKQFLNADYGFETIIPVQRTSLDFER---------------- 146
WP_014956256  64 -dDGDDI------------NIGFDLNVFAQAHRLIYITKHKFLGADYGMSTIVPIVGTDFNLNV---------------- 114
WP_060688242  70 -eNGEv------------hEMGKSVMAFANITLLTYVHDKPVLGGKYFAAAGVPIANLALNPSNf--------------- 121
WP_119334170  62 -aPGQ-----------------NDGTVTALANRFVWITNQKFLGADYGLEAIVPLQSTSFTFNG---------------- 107
WP_109037413 154 tieqvartAnAQDSKSTGIGDIELSPV-IHWEiGDHQSASFAPTIVVPTGDYDATRRANAGYgNFFTFRPSFQYAFI--- 229
WP_011686765 121 ----------GPISGGSGFADSYYLPLiLGWS-TERAGVRAMYGFLAPTGRFAPGADSNVGS-GYWTHTLSSGQTFYl-- 186
WP_012023232 120 ----------IDSKNSLAFTDMYVQPLqLGWH-NKRADFVFSYQMYLPTGRFTAGASDNAGL-GMFINEFSAGTTLFf-- 185
WP_012839079 113 --------A-GISDSRSGVGDVYLGPLvLGWH-GPQWDAVAGAGIWLDSASS--RDPASPGK-GYKSTMLTGGLTYYf-- 177
WP_013258473 116 --------A-GVDDSQFGIGDLYFEPFvLAWR-KPQWDVAFALGFYAPTA--DSGGSASPGL-GYWSFMETLGATYYf-- 180
WP_013721222 115 --------A-GISDSRSGVGDIYLGPLvLGWH-GPQWDAVAAAGMWFDTAST--SHPASAGK-GFKSTMLTGGLTYYf-- 179
WP_083829479 147 --------L-GVNSTETEIGDVFIGPVvLGWH-GQQWDAVFASGVWFDTGS--TAEPASAGK-GYKSVMTTLGGTYHm-- 211
WP_014956256 115 --------P-GVHDSEVGLGDIFIEPLiLAWH-TDRWDAVLGLGVNLPTGEYDWTEPASAGQ-GYTSGMMTLGATYYi-- 181
WP_060688242 122 ----------SLNEQQVGIGDMIVFPAaLSWT-FDRMALTARIGFFAPTGRYKAGASNNLGK-GYFSHFYTLGGTFYfgk 189
WP_119334170 108 --------I-GYSGSSRGLGDVFLGPVvLGWH-GSNWDSVFALGLWFDNGDFSATNPSSVGK-GYKSTMWTLGGTVYp-- 174
WP_109037413 230 GDG--WDLAARTVLSFNTRNKDNGYFSGHMFNLDWQAMAFV----------SDDVRVGVQGYFVRQLTGDTQKldGfsva 297
WP_011686765 187 AREkrLVFSAFEMYEFHTTQEGTGIHPGQTFDLDYSLMGVLhr------taGLALQVGVTGYGARQTTAKVGP--Eit-- 256
WP_012023232 186 NDKktFHFSALASYEINSKKKDTDIKTGDILSVEGGLGKTFymlnaektapKSILNAGLIYYFQYKVSNDKIP--Agn-- 261
WP_012839079 178 DAAktISASGLMRFERNGKNDM-GFRNGNQVTLEWGLGKHF-----------GAVQAGLVGYSQWQISDDKGP--G---- 239
WP_013258473 181 DQArtWSVSLLTRWLQNTESRDSDVTQGANVVAEYGAGKTIsl------srDLLFQFGVSGYTNLQLTDNSGT--T---- 248
WP_013721222 180 DGAktLSGSALMRYEFNGRNSA-GVRPGDQLTLEWGLGKSF-----------GAVSAGLVGYSQWQTTNDDGA--G---- 241
WP_083829479 212 DAAktWSFSALSRYEINFDDDN-GVDRGDSFLVEWGLGKRL----------SNGLELGLVGYDGWQLDENTGG--Dla-- 276
WP_014956256 182 DQAksWAVSALSRTLVYGEQDDTDITPGWEFIVDWGISKQFpi------seGLLIRPALVGYTYWQMDEDSGT--G---- 249
WP_060688242 190 DNR--FHFTGMNTYQLSSRQAGTGITAGNTNTFEWGLGVTF----------EKRFNVGLVGFHQYQTTPQKGG--P---- 251
WP_119334170 175 DSAktWSISALARYEQNGKQDQTGITPGDGLSIEWGIGKQI----------GGGKQLGLVGYYQKQTTKDSGP--G---- 238
WP_109037413 298 rqtalggykPLVDGNKASVNAAGPAIAWI-RNGGEFMLEGKLLQEFNARNRT----EGQSLWVTLSKPL 361
WP_011686765 257 ---------aeMSAQRYAVNAFGFAVNAA-FPKRRASVGFRFFKEFANRSTF----QGYSAQISAAIHL 311
WP_012023232 262 ---------fvLEPDKDQIGGLGAEVNYL-HIGCMTSAGLRWVSEFGAENRF----QGSTFFLTLAHVF 316
WP_012839079 240 -----------ATSQHSSRHALGAELVYP-VPGAGMFLKGAVYKEVSATAGTgalpKGSLVRFTVVKAF 296
WP_013258473 249 -----------NDDVRARSNAVGPEIHFTlLKPLVLQAYLRYLFEYGTEATS----EGQTLCLTLIGSF 302
WP_013721222 242 -----------ASTNKAARHAVGAELVYP-VPGAGVFLKGAVYKEFSATAGTgpqpKGSLVRFTLVKAF 298
WP_083829479 277 ---------pgQDQVKVEKHALGLEVGYF-WPSLGFGLNGAYLNEYQADNST----EGDLYRLTLTKIF 331
WP_014956256 250 -----------SSDEKGTNYAIGAEVNLFwLPPHLFQINLRVLQDFGTENEA----ETTKVVFSVVKSF 303
WP_060688242 252 ---------EVLRKMFHQQHGIGWGMSYA-TTe-kFSFAIRSYWEMMAANRP----QGNAFRLIVNYNF 305
WP_119334170 239 -----------ALPVKPSKSAIGVQFDYP-LMEHGVILKFAGYHEVSSNSDA----KGNLFRVTLIKVF 291
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