Conserved Protein Domain Family
ZirU_fam
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NF040485: ZirU_fam 
ZirU family protein
ZirU, as found in Salmonella, shares with ZirS the property of requiring ZirT for its type Vb-like secretion. This HMM describes a broader family of ZirU homologs. The N-terminal half of this HMM shows detectable homology (although scoring below the cutoffs set for the model) to ZirT (zinc regulated transporter), but no similarity to ZirS (zinc regulated secreted protein)
Links
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Statistics
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PSSM-Id: 468510
Aligned: 23 rows
Threshold Bit Score: 157.209
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_046082322  30 VLTSATTAPSVGYRPVA----VAGEEGLEVKGKLYIGQTLRID-KLFYTDKDGDgidn--ttgKGESvldkSEIKWFliN 102 Escherichia fer...
WP_000273696  29 DMASSATPASVGHRPVA----TTNAKKIEVSGELTTGSTLQIA-DVFIRDEDGDpls---ldkMNNA----DDIKWYlvD 96  Salmonella
WP_079793657  29 DMASSATPASVGHRPVA----TKEAKKVEVSGELTTGSALQIN-NVFIVDDDKDvls---ldkMNNA----DDIKWYlvD 96  Salmonella bongori
WP_166713654  11 SATSEPTLASVGYRPVQt---NEEGKKLTVKGNLTTGAQLEIT-NIAYTDSDGDqlsldkmvqSEEG------IKWYlvD 80  Hafnia paralvei
WP_109913074  43 SITSPATTAVIGHAPELka-gTITATDKNNDGVLGENDELKAS-GFDFSDKDKD---------TLVS----IVYEWH--- 104 Providencia
WP_154623874  43 SVTSPATKSVIGHAPVLktdgQIKANDKNGDNVLGENDTLEAS-GFAFDDADGDk--------VTIS------YEWL--A 105 Providencia
WP_104451266  84 NAPGVSGGGTTPPGSIIdpvaTPIVDVTDIKGVLQVGQTLTG--EYSFNANGGN---------TTDA----STMQWN--N 146 Pseudomonas lau...
WP_156639422 437 VGNELRLDATKMTSADLakdnRFEVTVNVVDGRGRNAQQHFII-DVIDIDPDGD---------GLSN------------- 493 Lysobacter gilvus
WP_097364335 550 DNQGNQSNSETLRVVVQppqvTAQGTFVISGDGARANGSDKIGvDFIIKDSNGN---------PLAN----REVVFH--T 614 Edwardsiella tarda
WP_084167192 666 SVNGIPIVNLSSSVVLVadnsSAILSLTVMTDGVFANGVATNAvQASVNDRQGN---------PVQA----HRVAFT--- 729 Budvicia aquatica

WP_046082322 103 KnVNNpdlsgTPSHSGTQFEIPKNASQSVIWITYKVAASAGHPYQAFSthkikltsKIKGLEGGTDGIITNRAsnv---s 179 Escherichia fer...
WP_000273696  97 NeAADps--gTPAATGTAFTIPADAGGKKIKIVYRIKTATGTPDSAFLpatvlltsASSGVSGDSAADGTISNklr--sv 172 Salmonella
WP_079793657  97 N-DAEvp-sgTPAATGTSFIIPADAGGKKIKLVYRIKTATGTPDSAFLpetvlltsTTSGVSGDLAADGIIANklr--sv 172 Salmonella bongori
WP_166713654  81 NnDSAts--gDPAGVGKTFEIPADAAGKKVKVIYRIQTDTGVPSNAFLptavlltkASSGVDGEGSADGSITNklklvni 158 Hafnia paralvei
WP_109913074 105 D-GKNv----IAGQTSDMLKLTSALLGKNITVKAVAKTDPAKTEPSESva----vaAATFIDIGGKTIAGGTN------- 168 Providencia
WP_154623874 106 D-GTT-----IPSETSDKLILTNKLLGKTITVKAIAHTDPNATDPAESkp----vgAKTYLDIKGTKLPDGSG------- 168 Providencia
WP_104451266 147 G-GQT--------DTDATYQLNASDVGRVLEFEVTAVNGAAVVGNTDR--------LDTANAPGVSGGGTTPP------- 202 Pseudomonas lau...
WP_156639422 494 ----------EQEQTHGTDPNKPDTDGDGLDDKTEVDNGTNPLDPNDP-------------------------------- 531 Lysobacter gilvus
WP_097364335 615 N-N---------GAQPGTITVTTDDNG--IAHFDVTNTSAGTTHVSAT------------------FDDQTQG------- 657 Edwardsiella tarda
WP_084167192 730 ----------ANNGAIMVASALTDVNGVALVTLTNTHSGITTVTADIN-----------------GYSQRVDT------- 775 Budvicia aquatica

WP_046082322 180 iIINNPGDKNPSNELNGTDSIN-SPIVGATLSTKCSFKDDekstasNCDSEgYSFQWfSANELNG--IYTKI--DNASNS 254 Escherichia fer...
WP_000273696 173 tINVVNESGKPTDELNGTNDAN-TPVVGGTLEAVLECAATaa---aECEVSnYNFTW-QMADAGTpdKFTDLnnTNAEKH 247 Salmonella
WP_079793657 173 tINVVNESGKPTDKLNGTNDAN-TPVVGGTLEAVLECATTaa---aECEVSnYNFTW-QMADAGTptAFTDLnnTNAEKH 247 Salmonella bongori
WP_166713654 159 eVKYPSGVSGPTNELNGNDIQG-TPIVGSTLVATLTCADDaa---dVCDVKnYNFKW-QMAENKSs-eYIDItpTGDIAH 232 Hafnia paralvei
WP_109913074 169 -IPTVNGNIVKSVTISGLTGAGsRPLVGDSLKANVTCHGT-------CDNN-LTYKW-QIQDSVNssKYTDI--SGATTA 236 Providencia
WP_154623874 169 -ITTVNGSVVKAVTISGLT--SgKPEVGKKLTADVTCHGT-------CDSSkLTYQW-QIENAAGsgLYSNI--PSATTK 235 Providencia
WP_104451266 203 -GSVIDPDGPDTVVVTGADVNG-NPIVGTPLTAQVYCMST-------CAPV-LNYQW-QIETVPGsaVYTSI---GANSD 268 Pseudomonas lau...
WP_156639422 532 --GTGNAPTGVNVHFNGNPLTG-SPMVGSVLDAAVTCAGDg-----QCPTT-LTYQW-QIESAIGsgTYIDI--VGATAQ 599 Lysobacter gilvus
WP_097364335 658 -IDITFANAVNSVIVTGLV--NgYPLVGTPLHAEVTCATG------ECPAS-LTYQW-QIEDAINsgNYVDI--PAATAV 724 Edwardsiella tarda
WP_084167192 776 -SFIVEPPVSVLVYRNGVALTD-NPVVDETLVAVPMCSTA------LCNATaINVQW-EMESFAGsgVFIAI--SGATSE 844 Budvicia aquatica

WP_046082322 255 TYTIPSDQQNLYFKVELT 272 Escherichia fergusonii
WP_000273696 248 KYIIKGTEQNKLFRVHVT 265 Salmonella
WP_079793657 248 KYIIKGTEQNKLFRVHVT 265 Salmonella bongori
WP_166713654 233 QYQIQGTQQNKLFRVLVT 250 Hafnia paralvei
WP_109913074 237 TYTVKGTEQKRKIQVIVS 254 Providencia
WP_154623874 236 EYTVKGTDQKRKIQVIVS 253 Providencia
WP_104451266 269 SYTPTKDDQKRKIRVEVS 286 Pseudomonas laurylsulfatiphila
WP_156639422 600 TYTVTAGDQKRRIRVQVA 617 Lysobacter gilvus
WP_097364335 725 DYIPVGTDQKRRIQVVIG 742 Edwardsiella tarda
WP_084167192 845 TLTVTKNLQKRAIRVVSY 862 Budvicia aquatica
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