Conserved Protein Domain Family
DNA_bind_WhiA
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TIGR00647: DNA_bind_WhiA 
DNA-binding protein WhiA
This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division]
Links
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Statistics
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PSSM-Id: 273194
Aligned: 11 rows
Threshold Bit Score: 332.032
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_003546596   5 ASEVKKELTSLEV-HPEHAKAELAAFLRMNGVLNLHDHQFSLDITTENPAIARRIFKLIKVAYGIEPLLIVSRKMKLKKN 83  Lactobacillus a...
A0RKU0         5 ASETKKELTNLEM-KECCEKAELSALLRMNGSLSFSNRRLSIDIQTENAAIARRIYTLLKKGYDVTVELLVRKKMRLKKN 83  Bacillus thurin...
WP_000006551   4 ASEMKNELTRIDV-DEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKN 82  Gram-positive b...
WP_011066859   4 ASEIKKELTAIEt-EECCQLAELAALVRMNGAISISRQGYSLDVQTENAAIARRIYTLIKDNYSIAVELLVRKKMKLKKN 82  Oceanobacillus ...
WP_003457993   4 SAKVKGEICRYIDiSKEEALAQISAIMKVCGTLAFSGRQISFKMTTENPASARLMFTILKDYFDIHAKLMVKKSNSLKKN 83  Clostridium per...
WP_000011310   4 TVAVKEEILG----QHHLSWHELSAIIKMSGSIGLSTSGLTLSVVTENAKLARHLYESFLHLYEIKSEIRHHQRSNLRKN 79  Streptococcus p...
WP_003862248   4 TSDIKQELAQVHVaKNSVRAAEVSAILRFAGEMQAVGGKLVIEANLDSMQVGMRLQEFIQGLYNSRVDVHTVNPTVSRKT 83  Corynebacterium...
WP_014877572   2 TAEVKDELSRLVVnSVSARRAEVASLLRFAGGLHIVAGRVVVEAEVDLGIIARRLRKDIYDLYGYNAVVHVLSASGIRKN 81  Mycobacterium s...
WP_030185801   4 TAAVKSEISQLPVtRTCCRKAEVSAVLRFAGGLHLVSGRIVIEAELDTGNAARRLKRDILEIFGHSSELIVMAPGGLRRG 83  Streptomyces vi...
WP_010874598   4 SVQIKHELATNPLiKTE--WSSFLAGYFQNGLKLLATGQWSFKTSTAT----------LKALFSNALQF----SFQIHET 67  Mycoplasma pneu...
WP_010869332   4 STQIKAELVQNKLiDKH--WNVFLAGFFQNNLKLLYNRNWSFKVQSEA----------LKEQFVQNLKF----DFKTKAS 67  Mycoplasma geni...

WP_003546596  84 NQYLVRLNQQ--VQEILENLQIWDTEKGLVT---RIPKRIMSSREG-AMSYLRGAFLAGGSVNNP-ETSRYHLEIYSTYE 156 Lactobacillus a...
A0RKU0        84 NVYIVRLVEK--SREILADLHIVRDDFSFIR---NISQELIEKKCC-KRSYLRGAFLAGGSVNNP-ETSSYHLEIFSLYK 156 Bacillus thurin...
WP_000006551  83 NIYICRTKMK--AKEILDELGILKDGI-FTH---EIDHSMIQDDEM-RRSYLRGAFLAGGSVNNP-ETSSYHLEIFSQNE 154 Gram-positive b...
WP_011066859  83 NVYIVRLKEE--VQLLLEELDLIINQYTIVR---TISNKYLEKDCC-KKSYLRGAFLAGGSMNNP-ETSSYHLEIFNYYE 155 Oceanobacillus ...
WP_003457993  84 NIYMVVVTEEmgVKKLLEITGILREIDGIMSldyHIDENLVDTEEK-KKAYIRGAFIGGGSISNP-EKT-YHLEFVTHSQ 160 Clostridium per...
WP_000011310  80 RVYTVFTDEK--VQDLLSDLHLADSFFGLET---GIDEAILSDEEA-GRAYLCGAFLANGSIRDP-ESGKYQLEISSVYL 152 Streptococcus p...
WP_003862248  84 PRYLVRIIDN--ADEIARRTGLVTRSGHVVK---GLAPSVVSGTISdAEAAWRGAFLANGSLSDP-GRSS-SLEVLCPGQ 156 Corynebacterium...
WP_014877572  82 TRYVVRVAND--GEALARQTGLLDMRGRPVR---GLPAQVVGGSVGdAEAAWRGAFLAHGSLTEP-GRSS-ALEVSCPGP 154 Mycobacterium s...
WP_030185801  84 SRFVVRVVAG--GDQLARQTGLVDGRGRPIR---GLPPQVVSGATCdAEAAWRGAFLAHGSLTEP-GRSS-SLEVTCPGP 156 Streptomyces vi...
WP_010874598  68 STHCEFSFRA--SQTEVDQL---------------LAFDATQSDLPlQKAYVIGAFLSGGSVSDLlHSSNFHLQISTNNE 130 Mycoplasma pneu...
WP_010869332  68 KKYFLFEFNA--DINVINTL---------------LKLDVTTSELVvKQVYLIAAFLSGGSVSDLiNSNNFHLQISSNNE 130 Mycoplasma geni...

WP_003546596 157 DHNEDLAKLMNeYFYLNAKMTKRRRGYIVYLKEAEKIGDFLHIVGALNAMLNFEDLRIMRDMRNSVNRLVNCDTANMKKT 236 Lactobacillus a...
A0RKU0       157 EHNDAICELMN-GFDLNSKTLERRKGYITYLKEAEKITEFLNIIGAHNALLRFEDIRIVRDMRNSVNRLVNCETANLNKT 235 Bacillus thurin...
WP_000006551 155 SHAEGLTKLMN-SYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKT 233 Gram-positive b...
WP_011066859 156 EHAESLQKLLN-SYGLHARLLARKNGFIVYMKEAEKITEFLSIIGAHKALFKFEDVRIVRDMRNSVNRLVNCETANLNKT 234 Oceanobacillus ...
WP_003457993 161 EYAEDLGKLIN-TFGLKAKVIQRKNSYIVYIKEGEQIVDLLNIIGAHTALLELENIRIMKEMRNNVNRLVNCETANLSKT 239 Clostridium per...
WP_000011310 153 DHAQGIASLLQ-QFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLNRANNAETANIART 231 Streptococcus p...
WP_003862248 157 ESALALVGCAR-RIGIAAKTKDSRGFDRVNVRDAEAIGALLTRMGAQKTRMLWEEKRIKRESRTPANRLANFDDANLRRS 235 Corynebacterium...
WP_014877572 155 EAALALVGAAR-RLGVSAKAREVRGSDRVVVRDGEAIGALLTRMGAQDTRLTWEERRMRREVRATANRLANFDDANLRRS 233 Mycobacterium s...
WP_030185801 157 EAALALVGAAR-RLSIPAKAREVRGVDRVVVRDGDAIGALLTRLGAHDSVLAWEERRLRREVRATANRLANFDDANLRRS 235 Streptomyces vi...
WP_010874598 131 LQIKQLMKLFH-PF----KQTTKRHQLLVYVKSYQAICDFFKLVEAFDGYLAFEENQLQKNFALEQVRKSNLEIANLMRT 205 Mycoplasma pneu...
WP_010869332 131 FQIQQLLKLFS-FF----KKTVKQNQLVVYLKSYEKICNFLKLIQAFDGYLAFENKQLEKSFTLNQLRKSNLEVANLMKT 205 Mycoplasma geni...

WP_003546596 237 ASASAKQVE-DIQLIQKEKGLDDLSEKLQILANFRLAHPELTLKEVADQIPDG---PISKSGVNHRFKKLHEIAE 307 Lactobacillus acidop...
A0RKU0       236 IGAALRQIE-NIRYIDETVGLDILPDKLREIAQLRRDYQDVTLKELGEMVSGG---KISKSGINHRLRKIDDIAE 306 Bacillus thuringiens...
WP_000006551 234 VSAAMKQVE-SIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTG---PISKSGVNHRLRKLNDLAD 304 Gram-positive bacteria
WP_011066859 235 IGAAFRQIE-NIKLIERTVGLDQLPDKLQEIAKLRIQYEDVSLKELGELVTSG---AISKSGVNHRLKKIDEFAE 305 Oceanobacillus iheye...
WP_003457993 240 VNAAVRQVE-SIKLIEREIGLARLPKNLREVAELRLTYPEESLKELGEMLEP----PVGKSGVNHRLRKIEKIAE 309 Clostridium perfringens
WP_000011310 232 VSASMKTIN-NISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQLADSLST----PLTKSGVNHRLRKINKIAD 301 Streptococcus pneumo...
WP_003862248 236 ARAAVAAAA-RVERAMKILG-DDVPEHLAEAGQLRVQHRQASLEELGRLADP----QMTKDAVAGRIRRLLTMAD 304 Corynebacterium glut...
WP_014877572 234 ARAAVAAAA-RVERALEILG-DSVPDHLAAAGKLRVEHRQASLEELGRLADP----PMTKDAVAGRIRRLLSMAD 302 Mycobacterium smegmatis
WP_030185801 236 ARAAVAAGA-RVQRALEILA-DDVPEHLAAAGRLRMEHKQASLEELGALADP----PLTKDAVAGRIRRLLAMAD 304 Streptomyces violace...
WP_010874598 206 LKTSTSTAE-QLKILINSADFKKQSLNFQRFCLVKLDHPDWSLEQIAQFFERKykvQITRSGIQHLNAKLKKLNQ 279 Mycoplasma pneumoniae
WP_010869332 206 IRSNNQTNQlQLKSFIKSSSFAKRPLNFQRYCLIKSDHPDWSLEQIANFFFTKyniKISRSGIQHFSVNLKKLCQ 280 Mycoplasma genitalium
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