Conserved Protein Domain Family
PLN02321

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PLN02321: PLN02321 
2-isopropylmalate synthase
Statistics
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PSSM-Id: 215182
Aligned: 21 rows
Threshold Bit Score: 1012.58
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
219115673   4 ILTASIVVTVWLASSPktisaftpINLRNGALKASKVRSSQSPTIRRNGLAAM----PEDANNELDTHIVLKQRQPRPAY 79 
145341061   1 ---------------MrgrtttttTTTTGLAGRRGKTARTARTARGAARGTNEwtrkVVVRAGSSGEGADGVARAPRPAY 65 
168017325   5 VVRKSQVSSSGLSSTFvvpfsggrNGVRSTK--------------------------TREVAPGAFIQCQGAQHKKRPQY 58 
168045468   1 ---------------------------------------------------MK----AGEVARGALIQCNGSALRKRPQY 25 
223993279   1 -MRIYAASLALALSYAcstsaftpSKHPSVTRSTHRPAAAVIAIASRSPTTTS----LSSSISEDPAIQELYRRRPRPEY 75 
242084512   5 LLSSP-------AKPFcsttkttpAPKATRFPSPRFLSSAHVLSAARRLRAVS----ARASQQQPPPPRGQ--QQRRPEY 71 
255084291   5 CAASAVVSRVAAPRPAkalkaagaAPVRSATHRARRVGG------------------RGVIRATGAPKDEDVVRAPRPEY 66 
302822527   1 ------------------------MDHRVIAPAPGSPAFQCKLRKSPSPSPAP----WKCRVLAASSSERQFFQRKRPIY 52 
302828332   1 -------------------------------MSAALGSTGPRVAPARAAPLCR----RALLLPAGRTRVVVRAEARRPDY 45 
302796547   1 ------------------------MDHRVIAPAPGSPAFQCKLRKSPSPSPAP----WKCRVLASSSSERQFLQRKRPIY 52 
219115673  80 IPGKIDDPDYVRIFDTTLRDGEQSPGATLTSAEKLEIAQMLAKLGVDVIEAGFPIASPDDFNAVKQIADIVGNDVFEDG- 158
145341061  66 VPGVISDPKYVRVFDTTLRDGEQSPGATLTSKEKLDIATSLARLGVDIIEAGFPIASPDDLEAVRGIAKKVGNEVYEDG- 144
168017325  59 IPNRIDDPSYVRIFDTTLRDGEQSPGATMTSKEKLDIARQLARLGVDIIEAGFPIASPDDLEAVRLIAKEVGNNVDDDG- 137
168045468  26 VPNRIDDPAYVRIFDTTLRDGEQSPGATMTSKEKLDIARQLARLGVDIIEAGFPIASPDDLEAVRLIAKEVGNQVDEDG- 104
223993279  76 IPGKISDPDYVRIFDTTLRDGEQSPGATLTSSEKLEIARNLAKLGVDIIEAGFPIASPDDFNGVKQIADVVGNEVFEDG- 154
242084512  72 VPNRIDDPNYVRIFDTTLRDGEQSPGATMTSAQKLVVARQLARLGVDIIEAGFPASSPDDLDAVRSIAIEVGNPAPAGDd 151
255084291  67 IPNKIDDLNYVRVFDTTLRDGEQSPGATLTSKEKLDIARNLAKLGVDIIEAGFPIASPDDLEAVRNIAKNVGNEVYPDG- 145
302822527  53 VPSRIDDPSYVRIFDTTLRDGEQSPGATLTSKEKLDIARQLAKLGVDIIEAGFPIASPDDLLAVKGIALDVGNRVDDDG- 131
302828332  46 IPNRIDDPNYVRIFDTTLRDGEQSPGATLTSKEKLDIARGLARLGVDIIEAGFPVASPDDFEAVRTIAMEVGNDVQPDG- 124
302796547  53 VPSRIDDPSYVRIFDTTLRDGEQSPGATLTSKEKLDIARQLAKLGVDIIEAGFPIASPDDLLAVKGIALDVGNRVDDDG- 131
219115673 159 ------YVPVICGLSRANQKDIQTAWDAVKGAKLPRVHTFIATSQIHMETKLNKTPDQVVEIAVEAVKFAKSLGCNDIEF 232
145341061 145 ------YVPVICGLSRANKKDIDAAWEGVRHALRPRIHTFIATSPIHMESKLRKTPDEVVAIAVEAVKYARSLGCDDVEF 218
168017325 138 ------YVPVICGLSRCNKKDIDAAWEAVKYAVRPRIHTFIATSEIHMVHKLKKSPEEVVQIARDMVAYARSLGCEDIEF 211
168045468 105 ------YVPVICGLSRCNKKDIDAAWEAVKYAVRPRIHTFIATSEIHMVHKLKKTPDQVVQIARDMVAYARSLGCEDIEF 178
223993279 155 ------YVPVIAGLSRANEKDIARAWDAVKGAMRPRIHTFIATSEIHMKSKLNKTPDEVVEIAVNAVTFAKGLGCDDIEF 228
242084512 152 ggadatHVPVICGLSRCNRKDIDAAWEAVRHARRPRIHTFIATSDIHMQHKLRKTPEQVAAIARDMVAYARSLGCTDVEF 231
255084291 146 ------YVPVICGLSRANKKDIDAAWEGVRHAKRPRIHTFIATSKIHMESKLRKTPDEVVQIAVDGVTYARSLGCEDVEF 219
302822527 132 ------YVPVICGLSRCNKADIAAAWEAVSHALRPRIHTFIATSEIHMKHKLRKSPDEVVQIATDMVGYAKSLGCQDIEF 205
302828332 125 ------YVPVICGLSRTKFADLERAWDAVRHAKRPRVHTFIATSDIHMKYKLRMTPDEVVENAVAAVRHLRSLGCNDIEF 198
302796547 132 ------YVPVICGLSRCNKADIAAAWEAVSHALRPRIHTFIATSEIHMKHKLRKSPDEVVQIATDMVGYAKSLGCQDIEF 205
219115673 233 SPEDAGRSDPVFLYRILSEVIVAGATTLNIPDTTGWNMPWEFGDLIKQLRENVKGAENVVFSTHCQNDLGLATANSLSGA 312
145341061 219 SPEDAGRSDPEFLYRILSAVVEAGATTLNIPDTVGICLPDEFGQLIAGIKANVKGIEGAVISTHCQNDLGLSTANSLAGV 298
168017325 212 SPEDAGRSDPEFLYRILEEVIKAGATTLNIPDTVGYTLPSEFGGLIAKLKANTPGADKVIFSTHCQNDLGLATANTLAGA 291
168045468 179 SPEDAGRSDPEFLYRILAEVIKAGATTLNIPDTVGYTLPSEFGSLIGKLKANTPGAEKVIFSTHCQNDLGLATANTLAGA 258
223993279 229 SPEDAGRSDPEFLYRILGRVIEAGATTLNIPDTTGWNMPWEFGELIKKLRENVPGAENVVFSTHCQNDLGLATANSLSGA 308
242084512 232 SPEDAGRSNREFLYHILGEVIKAGATTLNIPDTVGYNLPYEFGKLIADIKANTPGIENAIISTHCQNDLGLATANTLAGA 311
255084291 220 SPEDAGRSDPEFLYRILAAVVEAGATTLNIPDTVGICLPEEFGALIAGIKANVPG--QYIISTHCQNDLGLSTANSLAGV 297
302822527 206 SPEDAGRSDPEFLYRILAEVIKAGATTLNIPDTVGYTLPSEFGRLIAMIKENTPGSQSVVISTHCQNDLGLATANTLAGA 285
302828332 199 SPEDAGRSDPQFLYRILGEVIKAGATTLNIPDTTGWNLPHEFGGLIAAIRKNTPGAENVIISTHCQNDLGLSTANSLAGA 278
302796547 206 SPEDAGRSDPEFLYRILAEVIKAGATTLNIPDTVGYTLPSEFGRLIAMIKENTPGSQNVVISTHCQNDLGLATANTLAGA 285
219115673 313 LNGARQLECTINGIGERAGNASLEEIVMSLALKGATKFSGgpgtgkLFTAVNPVYITPTSKMVSEYTGMACQPHKAIVGA 392
145341061 299 ANGARQVECTINGIGERAGNASLEEVAMSIFMRGQSRLAG------AYTGINPVYIYPTSQMVKNYSGMAIQPHKAIVGA 372
168017325 292 HAGARQVEVTINGIGERAGNASLEEVVMALRCRGQERLGG------LYTGLNTKHIAVASRMVADYTGMVVQPHKAIVGA 365
168045468 259 HAGARQVEVTINGIGERAGNASLEEVVMALRCRGQEQLGG------LFTGLNTKHIAVASRMVADYTGMVVQPHKAIVGA 332
223993279 309 LNGARQLECTINGIGERAGNASLEEVVMSLALKGDEQFKGgpgtgkLYTAINPVYITPTSKMVSEYTGMKCQPHKAIVGA 388
242084512 312 RAGARQLEVTINGIGERAGNASLEEVVMAIKCRRE-LLNG------LYTGIDSRHITLTSKMVQEHSGLIVQPHKAIVGA 384
255084291 298 ANGARQVECTINGIGERAGNASLEEVAMSIWMRGQEKIFG------ARTGINPVYIYPCSKMVREYSGMAVQPHKAIVGA 371
302822527 286 YAGARQLEVTINGIGERAGNASLEEVVMAIRCRGDEQLNG------LHTGIKPKHIAVTSRMVSDYTGMTVQPHKAIVGA 359
302828332 279 MAGARQIECTINGIGERAGNASLEEVVMAISLRGKDQMNG------LYTGIRPVHIYPMSKMVSDYSGMIVQPHKAIVGA 352
302796547 286 YAGARQLEVTINGIGERAGNASLEEVVMAIRCRGDEQLNG------LHTGIKPKHIAVTSRMVSDYTGMTVQPHKAIVGA 359
219115673 393 NAFQHESGIHQDGMIKNKSTYEIMTPESIGLMRGEsQsgAGIVLGKHSGRNAVGTRLRELGYDLDTEKLNAVFVRFKQVA 472
145341061 373 NAFAHESGIHQDGMLKNKLTYEIIAPEQIGYFRGEnD--VGVVMGKHSGRHALSSKLKQLGVPMEGDALDEVFNRFKLVA 450
168017325 366 NAFAHESGIHQDGMLKHKGTYEILSPDDIGLVRAD-A--SGIVLGKLSGRHALKQRLNQLGYEVDGQELDDVFKRFKAVA 442
168045468 333 NAFAHESGIHQDGMLKHKGTYEILAPEDIGLVRAD-A--SGIVLGKLSGRHALKQRLNQLGYEIDGQDLDDVFKRFKAVA 409
223993279 389 NAFQHESGIHQDGMIKDKSTYEIMTPESIGLMRGEsQsgAGIVLGKHSGRNAVGTRLREMGYDLDMDKLNAVFARFKEVA 468
242084512 385 NAFAHESGIHQDGMLKNKGTYEIISPDDIGLTRAN-E--FGIVLGKLSGRHAVRSKLVELGYEIGDKEFEDFFKRYKEVA 461
255084291 372 NAFAHESGIHQDGMLKNKLTYEIIAPETIGYFRGEgD--VGVVMGKHSGRHALKSKLKQLGFPLEGDELNEMFDRFKLVA 449
302822527 360 NAFAHESGIHQDGMLKFKGTYEIMCPEDIGLVRAD-E--AGIVLGKHSGRHALKTRLSQLGYELESKQLDDVFKRFKAVA 436
302828332 353 NAFAHESGIHQDGMLKNRETYEIMTPESIGLPRQEqD--RGIVLGKHSGRNALSSRLRSLGYELSTSELDDVFKRFKALA 430
302796547 360 NAFAHESGIHQDGMLKFKGTYEIMCPEDIGLVRAD-E--AGIVLGKHSGRHALKTRLSQLGYELESKKLDDVFKRFKAVA 436
219115673 473 ERKKgGLEDEDLEALVSDQAGL---SNLLWEVTGLQVATGLSGIPTATVKMLGPDGLERYVACTGTGPVDAVYKAIDQIM 549
145341061 451 ETKLgGVNDDELLAIVRDGESV---QDPAWSLETVQVVCGTTGLPTATVKMLAKDGTVHISAVVGTGPVDAAFKAIDALV 527
168017325 443 EKKK-NVSNEDLETLLFDEVFQ---PETLWSLGLIQVVCGNAGISTATVKLEGPDGAQHIGMSVGTGPVDAAYKAVDTIV 518
168045468 410 EKKK-NVSDDDLEILLSDEVFQ---PETLWSVGLIQVVCGTSGLSTATVKLVGPDGVEHIGMSVGTGPVDAAYKAVDTIV 485
223993279 469 EKKKgGLDDDDLESLVMDQSQS---TNELWKVTGLQTTTGISGIPTSTVKMMGPDGVERFVSATGTGPVDAVYKAIDQIM 545
242084512 462 EKKK-RVTDEDLEALLSDEIFQ---PKLIWSLADVQATCGTLSLSTATVKLIGPDGEERIACSVGTGPVDAAYKAVDQII 537
255084291 450 EQKTgGVGDDEIIALVTSGAGQgddTAVTWKLDEVQVVCGTMGLPTATVKMTGPDAVTRINSAVGTGPVDAAYKAIDGLC 529
302822527 437 DKKK-SLSDVDLEALLSDEVFQ---PEVVWALLDLQVVCGTLGLSTATVKLSGPDNIQRVGTSIGTGPVDAAYKAVDSIV 512
302828332 431 DKKK-GITDEDILALMSDELHQ---PKVIWELLDLQVVCGTMGMPTATVQMQGPDGIARIGVGVGTGPVDAAYKAIDSLV 506
302796547 437 DKKK-SLSDVDLEALLSDEVFQ---PEVVWALLDLQVVCGTLGLSTATVKLSGPDNIQRVGTSIGTGPVDAAYKAVDSIV 512
219115673 550 GVSVRLEAYQLNSVTEGIEAMATTRVVIAPLEggpndSISI----HSQTGVSRNRKFSGSGSDTDIITSSARAYVSALNK 625
145341061 528 GLDVVLTEYRVTAVTKGINSLAETTITVKPREgaeqkLGADvfktNLQTGETAVRSFTATGADTDIVVSSARAYVIALNR 607
168017325 519 KAPVTLLEYSLNSVTEGIDALAHTRVQIRALD-----SLTVt---HAQTDSQVPRTYSGTGASEDVVVSSCRAYISALNK 590
168045468 486 KAPVTLLEYSMHAVTEGIDAIAHTRVQIRALD-----PLTVt---NPQTGSQVPRSYSGTGAAEDVVVSSVRAYISALNK 557
223993279 546 GVSVELESYSMNSVNEGIEALASTRVVIVPNAngpndSVVM----DAQTSQLRERKFSGSGSDTDIITSSARAYVSALNK 621
242084512 538 QIPTVLREYSMTSVTEGIDAIATTRVVVTGDV-----SINAk---HALTGRSFNRSFSGSGASMDIVVSSVRAYLSALNK 609
255084291 530 RVKVDLVEYTVNAVVEGIESLAQTRVSIRAKSdqtmpGAMMk--aNVQTGNVEARTFMATGADSDIVVSSARAYVAALNR 607
302822527 513 QIPVTLLEYSMNAVTEGIDAIANTRVVIRAEN-----STPVt---HAQSTEPVQRSFSGSGASEDVTVSSVRAYVSALNK 584
302828332 507 RVEAELVDYSVSSVTQGIEALAHTRVMIRPAG-----KMSDqgysEHAALGTVQRQFSGSGANEDIVVASARAYISALNK 581
302796547 513 QIPVTLLEYSMNAVTEGIDAIANTRVVIRAEN-----STPVt---HAQSTEPVQRSFSGSGASEDVTVSSVRAYVSALNK 584
219115673 626 LLKWNARSREQAREEKTNGSGVG 648
145341061 608 MTEYVTKAYVVEAVASR------ 624
168017325 591 MLTFRAAKKQPIVGLRSEEQTAG 613
168045468 558 MLTFRVAKHHAKGANRSEVHAAG 580
223993279 622 LLTWQMRRVANGASDANDSGIGD 644
242084512 610 ICSFAGAVKASSEVPEIASVPST 632
255084291 608 MISFMRSNAETVAAEAVIDIVAE 630
302822527 585 VIGFSKAVPSSESSVSATQATTV 607
302828332 582 MIGWMSVAQKVAPRTRSSSLAAG 604
302796547 585 VIGFSKAVPSSESSVSATQATTV 607
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