7Y4N,1SEM,1WA7,8F2P,7UY3,2V1Q,2RQW,4J9H,1ZUU,1NG2,2VKN,2LQN,1VA7,1NG2


Conserved Protein Domain Family
SH3_1

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pfam00018: SH3_1 
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SH3 domain
SH3 (Src homology 3) domains are often indicative of a protein involved in signal transduction related to cytoskeletal organisation. First described in the Src cytoplasmic tyrosine kinase. The structure is a partly opened beta barrel.
Statistics
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PSSM-Id: 394975
Aligned: 55 rows
Threshold Bit Score: 37.183
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7Y4N_A    7 QALYDFVPQE-SGELDFRRGDVITVTDRSDE-NWWNGEIG---NRKGIFPA 52   fruit fly
P02549  983 MALYDFQARS-PREVTMKKGDVLTLLSSINK-DWWKVEAAd---HQGIVPA 1028 human
P13395  976 VALYDYTEKS-PREVSMKKGDVLTLLNSNNK-DWWKVEVN---DRQGFVPA 1021 fruit fly
P27637  265 YALYAFNGHD-SSHCQLGQDEPCILLNDQDA-YWWLVKRIt-dGKIGFAPA 312  Saccharomyces cerevisiae S288C
2V1Q_B    6 IVQYDFMAES-QDELTIKSGDKVYILDDKKSkDWWMCQLVd-sGKSGLVPA 54   brewer's yeast
2RQW_A    6 IVLYDFKAEK-ADELTTYVGENLFICAHHNC-EWFIAKPIgrlGGPGLVPV 54   brewer's yeast
P40996  129 IVQFDFAAER-PDELEAKAGEAIIIIARSNH-EWLVAKPIgrlGGPGLIPL 177  Schizosaccharomyces pombe 972h-
P00522  193 VALYDFQAGG-ENQLSLKKGEQVRILSYNKSgEWCEAHSDs-gN-VGWVPS 240  fruit fly
4J9H_A    9 VALYDFVASG-DNTLSITKGEKLRVLGYNHNgEWCEAQTKn---gQGWVPS 55   human
1VA7_C    7 EAAYDFPGSGsSSELPLKKGDIVFISRDEPS-GWSLAKLLd-gSKEGWVPT 55   brewer's yeast
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