1JN1,3F0D


Conserved Protein Domain Family
IspF

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COG0245: IspF 
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Lipid transport and metabolism]
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Statistics
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Structure
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COG0245 is a member of the superfamily cl46543.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1JN1_A         2 IRIGHGFDVHAFG----------------------------------EDRPLIIGGVEVP-YHTGFIAHSDGDVALHALT 46 
WP_003514705   1 MKVGIGQDSHRFDfd-------------------------------nKDKKLVLGGVVLE-GYPPLKGNSDADVILHSLT 48 
WP_012543892 208 rLEGIGWDFHRFS----------------------------------ENAPLILGGVRIEdADVGLESWTDGDVIIHAVA 253
WP_012634794  13 MKVGIGQDSHRFDfq-------------------------------nNSKKFILGGVIFD-DVTPLDGNSDADVVLHALT 60 
WP_012993563  17 FITGLGQDHHRFItkepgqtgfdnrgetkmgacldarfrvktadggaNKYGLRLAGVDID-CDCLIEANSDGDVVIHALI 95 
WP_013043387   3 VKTGLGLDSHRFVeg-------------------------------eTDKAFVLGGLVFE-DAPALAGNSDADVILHALA 50 
WP_015359940   2 FKVAIGQDSHRFDfd-------------------------------nHDKKLVLGGVFFD-G-PPLKGNSDADVVLHALT 48 
WP_045472093   3 VKMGLGQDSHRFDfe-------------------------------nNHKPLILGGVLFE-GEPPLQGNSDADVVLHALC 50 
WP_053819797   3 IKTGLGQDSHQFEk--------------------------------kSGKDLVLAGIKFD-YPFGLKGNSDADVIFHSIT 49 
WP_062155409   1 MKTGLGQDSHRFVla-------------------------------dEQKTLLLGGVVFP-DELGLAGNSDADVVLHAIT 48 
1JN1_A        47 DAILGAAALGDIGKLFPDTDMQYKNADSRGLLREAFRQVQE--KGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDLQCD 124
WP_003514705  49 NAISGVTCVNILGKISDELCLEKGITDSKVYLKEALKYLN----GQKIIHVSISIECLTPKITPHIPAIRSSLAKLLDIP 124
WP_012543892 254 DALLSTLGQGDLGTLYPNS-QLWKGGSSTDILADVMERMRK--KHVLLEKATVLLLADKPMLKHWIDPITRNLSSLLNAP 330
WP_012634794  61 NAISGVTCVNILGKVSDEMCLERGITDSSEYLREALKYLV----DVKVVHVSISIECSYPKISPKIAEMRKSISELLGIP 136
WP_012993563  96 NAISGLGCPPFLGKPADALC-RAGIKDSRVYLAESLRILQEihPRLTVVHASFSIEALKPKLWLHIPAMRSSLAKLLNLP 174
WP_013043387  51 DAISGVTGRTVIGKVADEMC-QRGITDSKEYLNVALEDLG----DWQISHVSIVLECQRPKIDPKVPALRESIAALLGIA 125
WP_015359940  49 NAISGITGVNILGETADRLCLEQGITDSSVYVREALKYLN----G-EICHVSFSVECLKPKISPKIPDMKKSIARLLNID 123
WP_045472093  51 NAISGITGVNILGAISDDLCLRQGITDSRVYVQTALHHLQ----AWRICHVSCSIEGKRPKITPKIPAMKHSLAQLLGLA 126
WP_053819797  50 NSISSITGKNILGDVADQLv-KTGIKESAKYLQIALDDLG----DWKINHIAVALECAKPKIANHVEAMKESIANTCQIN 124
WP_062155409  49 NGISGITGVNILGKISDDLCLQQGITDSRVYLQEALKYLH----GWQICHISISIECRTPKITPRIPEMKQQIAALLQIT 124
1JN1_A       125 IEQVNVKATTTEKLGFTGRQ-EGIACEAVALLI--R 157
WP_003514705 125 ENSIGITATTGEGLTQFGQG-QGIQVFSCITVE--- 156
WP_012543892 331 ---VYLSVTRSEG--IIGKDlNGMISLSFVNCVevK 361
WP_012634794 137 ENCVGITATTGEGLTAFGQG-KGVQAFCIVTAI--- 168
WP_012993563 175 ITSIGITATTGEGLSGMGRG-EGIGVTCLLTAQ--E 207
WP_013043387 126 FEDVCITATTGEKLNDVGRG-LGIHATVIVTVC--G 158
WP_015359940 124 EKNIGITATTGEGLTDFGKG-LGIQCFCILTAL--V 156
WP_045472093 127 VQDIGITATSGEGLTAFGRG-EGIQVFCMVTAI--N 159
WP_053819797 125 RSDVGITATSGEGLTSFGRG-EGIQAITIITVS--K 157
WP_062155409 125 TTDVGITATTGEGLTDFGRG-LGIQVFCIVTAI--Q 157
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