Conserved Protein Domain Family
HU-HIG

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pfam18291: HU-HIG 
HU domain fused to wHTH, Ig, or Glycine-rich motif
Rapidly-diverging family of HU domains predominantly observed in the bacteroidetes lineage with a predicted role in recognition and possible interception of the DNA of parasitic elements, a counter-conflict strategy preventing incorporation of these elements into the host genome.
Statistics
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PSSM-Id: 436389
Aligned: 34 rows
Threshold Bit Score: 126.541
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013547567   1 MSAYYDLYETPS-PD--GKEd--KKSLHARICPKRTYTRKEFVEHVAMFQHLPKNMIGAALDACIDDLCDLLADGNIVEL 75  Bacteroides hel...
WP_005855526   1 MALKFKLVMRKN-LG--EDHesiPEKVYAQMVYGDLVTFDEFAEEVADSSGVGSASVKAVLDRMNVVLVRHLQHGRRVSV 77  Parabacteroides
WP_002664579   1 MSIKYKVIEKGQ-PGvaGGG---TKKFYANVVTEGELSVDDLVKQIEKFSALSEADIRGVIIALENVIQQGLADSKIIRL 76  Flavobacteriales
EPT33225       1 MSVKYKVIERGQ-PGvpGGG---TKKFYAAAVLSGEKTLAGLTRDIEKISTVSGADIRAVLYALVDVMTGSLADGYAVRL 76 
WP_024997362   1 MSVPVTVVARKN--PakQNE---PEKFYAMAQAAGEMNFRSLCKDASEGCTVMRSDIAAVLYALIDSMMKSLAKGEIVRF 75  Bacteroides gra...
wustl:BD0283   1 MALNYSVALRPN--PlkKDE---PAKAYATAQVNGELSLKQLSRRVSMQTTVSRADVVAVLISTVENLLDALQEGKQVDF 75 
CDD20787       1 MAVKYSLAKMNT--KlnGKS---YEKVYAHAQVNETTSLKKFSQLIASQTTVSRADVSAVLISSVENLVMELQRGNQVEF 75 
CDE61851       1 MALIYTLVKRRDmSKgaLEG---AQLYYAQTSVTKRLDLNTICSRIEMYCTASRGEIILVLDGLIKVMNEALAEGESIHL 77 
Q8A392         1 MALEYVVTKRVF-GF--DKDk--NEKYVAKSVRSGRVSFSKMCGKVSRLCGVHRKVVDLVVSGLVDMMAEDIDDGKSVQM 75  Bacteroides the...
Q8A4Q9         1 MALRYVVKKRMI-----GFGkekTEKYVAQNFITNTVNFKDLCDEISKVGMVPSGAVKFVLDALIDTLNINLNKGISVQL 75  Bacteroides the...
WP_013547567  76 GELGFFSTSLKClRETDDeKKKIRSESVRFQNVHLRISSTFRRNIKSAmTLER 128 Bacteroides helcogenes
WP_005855526  78 GELGLFRFCFGS-SGVPD-EKTFSTNLIREPKVRFYPGKALRVAKSRT-SFEK 127 Parabacteroides
WP_002664579  77 EKLGSLYPTLSS-NGVAT-EKEFTANQIKSVSVNYRPGTRIVEAMKAA-GFEK 126 Flavobacteriales
EPT33225      77 GELGSLRVSISS-ESKLV-AEDVTAAAIRRARVIFTPGKGIKDTLADL-RFEK 126
WP_024997362  76 GDFGSFQVGVSS-TGVEK-KDDFSANQVKGAHIIFRPGIDLTEMIKTL-TFKK 125 Bacteroides graminisolvens
wustl:BD0283  76 GDLGKFRLQILN-EGAES-LEKFTSTNITGVNIQYIPGEDLKNIFAGL-EFQP 125
CDD20787      76 GELGKFRLQLMS-DGTDT-ASDFTSDNIKGVRIQFVPGDDLADMFNQM-EFTP 125
CDE61851      78 GEFGSFRMVAGS-KGAAT-PEEFEVSMIKKPRIVFYPGTMLIGTTQNA-KFER 127
Q8A392        76 GEFGIFSPTIRA-KSADD-EKEVSSKSIVQRKILFYPGKIFKTTLDDM-SITR 125 Bacteroides thetaiotaomicron
Q8A4Q9        76 GDFGQFRPGISS-ESQET-EAAVDSDTIRRVKIVFTPRYKFKDMLKKA-SIQK 125 Bacteroides thetaiotaomicron
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