Conserved Protein Domain Family
CpdA

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COG1409: CpdA 
3',5'-cyclic AMP phosphodiesterase CpdA [Signal transduction mechanisms]
Statistics
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PSSM-Id: 441019
Aligned: 729 rows
Threshold Bit Score: 51.6155
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_080598873 403 L-RIHHISD---IHFGpksaqrvdvkergqhgS--AmgGAlgpprvCDHYVEHVaelaAsgRAPHLLVVSGDVA-EWA-D 474
NP_601187      3 T-TLWAVSD---LHAA-------------------V--KA------NADPIENIq--pK--DPSDWLIVAGDVA-ERT-- 44 
ACR41435       1 --MIVLISD---LHKSlns-----------ieE--M--ES------VKWLLDILd---D--LKPDYLIGAGDWG-E-GmT 47 
WP_015809490  50 L-IFQMVGDtggLNTAga------------rqQvvK--QM------AAQYTNAAt---Kh-DEPSFLYHLGDIVyHYG-E 103
WP_096378569   1 M-RLFAVSD---LHVD-------------------Y--PD------NAQWVQSLsr-wD--YRDDALILAGDIS-HRP-- 43 
WP_126450471   1 --MILFVSD---VHKSykrr---------rvdE--T--VA------VDWLLKVIk---K--WEPDYLISAGDWD-E-GmS 49 
WP_015088577   1 M-QLLAISD---LHLE-------------------S--GL------NRIALEDLp---S--YPEDWLIIAGDVA-EQI-- 41 
WP_050429995   1 M-KLLALSD---LHVG-------------------H--PR------NREVLGELt---P--RPDDWLILGGDLG-ETE-- 41 
WP_012185782   1 MaKLLLISD---LHKTie------------pgE--Y--EA------VNWLIGIId---D--VKPDALISAGDWG-EYl-T 48 
WP_014399418   1 M-KLYAISD---LHLR-------------------H--KE------NHEALAALa---P--RPDDWLIVGGDVG-ETL-- 41 
WP_080598873 475 DAQYAEA-RSWLEqvsrhLaDhprLPpdepnVLLVGGNHDV---------DWrqaaepaqagtqarhEPFA--RAFgdhp 542
NP_601187     45 -ELVLEI-LARLRr---rFa----------kVIWVPGNHEL---------FSrsa----------drYQ----GRDky-- 84 
ACR41435      48 IDDFSNI----LSr----------Tr-----LIAVYGNHE----------------------------NFSiiKSFsir- 79 
WP_015809490 104 AEQYEGQfLGPFEy-----yP---GP-----IYAIAGNHDSdinpesethYDsl------------eAFYT--T-Fcntc 155
WP_096378569  44 -QLLGAC-LGELAa---rFa----------rVLFVPGNHDL---------WVlg-----------edPGKT--SLDkl-- 84 
WP_126450471  50 PEDFQKI--GSL------------TK-----FLTVYGNHE----------------------------NFPliKPIamn- 81 
WP_015088577  42 -DIVADA-LAILAn---hFa----------kVIWVTGNHEL---------WSrp-----------nsGEPI--GANry-- 82 
WP_050429995  42 -EHLRWV-LDTLGp---rFq----------qLVWVPGNHEL---------YVhpd----------dtASPR--GEEry-- 83 
WP_012185782  49 QDDLYAV----ISr----------VP-----LITVYGNHE----------------------------NFGliKHYaigd 81 
WP_014399418  42 -ADMELM-LSTLTa---rFr----------qVVWVPGNHEL---------WTmps----------ekPPLK--GEAry-- 83 
WP_080598873 543 rcarpp---leeppatrplAvaRYAd-L---------------------G-VEFALLGSAef-----gGQeek------- 584
NP_601187     85 -----------------seL--VEGcrKidvltped--------pyltfggVTIVplftlyd-ysfrrpGftveqavqaa 136
ACR41435      80 ---------------------dgqIirV---------------------GkMRITGIN----------GL---------- 97 
WP_015809490 156 pktiyfgqhiqrksqvqpnV--YWTmqT---------------------PlATIIGLYTNvp----kyGC---------- 198
WP_096378569  85 -----------------deV--RRLahEhgatt-----------rawrhGgTLVApllgwydhgfaepGEelkqmwm--- 131
WP_126450471  82 ---------------------dgkAylV---------------------DdFRVAGIN----------GL---------- 99 
WP_015088577  83 -----------------naL--VARarSlgvitpedpfplwpgslpqgvDkLIIApmfllyd-ysfrpdNvplelvvewa 142
WP_050429995  84 -----------------lrL--VELcrGagvitpedp----yvtwtgegEpHLIAplfllyd-ysfrpaHvaeqdavawa 139
WP_012185782  82 g----------------------airrI---------------------HgLTLSGIN----------GL---------- 98 
WP_014399418  84 -----------------lrM--VDLchRygaltpedp----yprwpgegPpRVIVpmflgyd-ytfrpdTvpadkalewa 139
WP_080598873 585 ----------dpVR-D-----------EllsligrlrQgaMdepdaEraaALRdhvaridpglvhnADLQRlrrT---Rw 639
NP_601187    137 rdrqvmmtdefsIApfvdi---rawcwD---------R--L-----A---YSI-------------KRLSK---I---Ng 175
ACR41435      98 ------------IG-D-----------Nr--------NygIn---pDk--FLKi-----------iNKL---------K- 119
WP_015809490 199 ------------IK-K-----------D---------Q--K-----N---WFI-------------KELQH---AakySt 219
WP_096378569 132 -------dyracrW-Ppgy------daA---------R--I-----A---AHL-------------AALDP---L---P- 158
WP_126450471 100 ------------VG-S-----------Gr--------PysIs---pEd--FTAa-----------fRRAGR-------Rk 124
WP_015088577 143 eqthnvctdevlLS-PatyksriawchT---------R--L-----A---QTE-------------MRLNL---E---V- 182
WP_050429995 140 mesgllcsdemlLD-PrpypsrtawchA---------R--V-----D---ATA-------------ARLAA---A---P- 179
WP_012185782  99 ------------ISqS-----------Dg--------EytIg---fNr--FMRv-----------iDRIRR-------Kv 124
WP_014399418 140 weddlmctdevlLH-PepyptrqawchA---------R--V-----E---RTR-------------ARLER---L---P- 179
WP_080598873 640 hA-----PIrIAVLHHPV-SPL---PSTELarfggLI-N-AGE---VK-DALA----HK--EFCLVLHGHS----HTGWf 694
NP_601187    176 -------PT-ILINHWPLvVEpt----------yqMR-WqELAl--WCgTRHTrgwaERy-NAEAVIYGHL----HMPGi 229
ACR41435     120 -D------IdILITHQPPy--L---PEIYPk----MRyN---EateLM---LKa--vEQi-KPKLHFNGHMtggcYSYYe 174
WP_015809490 220 -Dk----AI-ILCLHHAPySAdlnhgSSLV--------M---Id-fLE-TAFA----TAgvKPDVVFSGYV----HNYQr 272
WP_096378569 159 -PregvdRT-ITVSHFLPrLDlipd-------yvpAR-HrILDp--VLgSAGIerrlRAl-GADLHVYGHS----HINRd 221
WP_126450471 125 --------VdILVMHQPPy--L---PEVYPn----MRrD---EgglLA---LEa--iREv-SPRLFLNGHMtgecYTYYr 178
WP_015088577 183 -Pan--aHT-ILINHWPLrRDli----------siPL-VpRFTp--WCgTLLTedwhIRf-NAYAVVTGHL----HTRRt 240
WP_050429995 180 -Pl----PK-VLINHFPLrEDlv----------rlRW-IpRFSi--WCgTRKThdwhLRf-GAGVVVTGHL----HIPRt 235
WP_012185782 125 -Ns-----LdLLIMHQPLy--L---PDQYPw----MKnD---EysaMA---LEa--aRLl-KPRLLLNGHMtgecYNYGk 180
WP_014399418 180 -Pe---cST-ILINHYPLrYEhv----------rlPR-IpRFSi--WCgTRLTedwhTRy-RAEVVVTGHL----HMPSt 236
WP_080598873 695 -------GkeqwperhedwtIRIA-AAPSLSSrEvqe----------------------------hnGYNEIEI 732
NP_601187    230 tn---vnG------------VKHI---------Evslg-------------------------------ypreW 248
ACR41435     175 f----ewGk-------------YLrVDSSsr----------------------------------frCYAIIDk 197
WP_015809490 273 fskqysdGk----------tVPFI-VAGAGGF-EdlhslanpndpaydtkssaldqvqlenycdnkqGFLKIEI 334
WP_096378569 222 vv---ldG------------VRYV---------Nnafg-------------------------------ypqeT 240
WP_126450471 179 f----pwG------------THYLrVDSSqe----------------------------------ckHYAVLEg 202
WP_015088577 241 dm---lgK------------TRFE---------Evslg-------------------------------yarqW 259
WP_050429995 236 dw---vdG------------VRFE---------Evsfg-------------------------------yprqR 254
WP_012185782 181 y----ewGn-------------YLrVDSSqr----------------------------------fkCYAVLNt 203
WP_014399418 237 lw---rdG------------VRFE---------Evslg-------------------------------ypmqW 255
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