7BTX


Conserved Protein Domain Family
MDM10

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pfam12519: MDM10 
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Mitochondrial distribution and morphology protein 10
MDM10 is a family of eukaryotic proteins that forms a subunit of the SAM complex for biogenesis of beta-barrel proteins, though not porins, into the outer mitochondrial membrane.
Statistics
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PSSM-Id: 432608
Aligned: 58 rows
Threshold Bit Score: 416.223
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7BTX_L         1 MLPYMDQVLRAFYQSTHW----STQNSYE--------------DITATSR-TLLDFRIPSAIHLQISNKSTPNTFNSLDF 61 
CCF60433       1 MLDYMDYIVRAFEKSTNW----NRDSSYE--------------NITSTSR-ALLEFHIPKTFKFQTSNRSTTNTFSTLEI 61 
CCC70664       1 MLDYMEYVVKTFHQLTNWn---PQANSYE--------------HLTDTSE-ALLDFTIPNSFKFQLSNNSSPYTYNTLEI 62 
XP_003671683   1 MLNYMEYVARSFQNATNWn---PSSNSYE--------------YITETAR-SLIDFQIPDSFRFQLSNNSSNVSYNTLEV 62 
A7TNL0         1 MIEYMNYVIKSL----------QSNNDYE--------------HLTLSSR-SLLNFKIPNAFKFQLSNKSTPYTYNTIDI 55  Vanderwaltozyma...
CCE65418       1 MLEYMDYIVKAFEISTNWpataSRNGAFShmngsgynsvefedNMTATSD-NLLNFYIPNVFKFQLSNKSSPFTFNTIDI 79 
CCE94206       2 MLDYMDYISRAFEQSTNW----NRDNSYA--------------NITATTS-ALIDFSVPSAFEFQVSNASTPFTFNTMRV 62 
C5E1U4         1 MLDYMDYVQRQFEKSTDW----NYDNSYA--------------NILASSR-NILDFPVPNQFKFQLSNNSTPHTFNTMEV 61  Zygosaccharomyc...
AQZ11016       1 MLDYMDYVIRQFEKSTNW----NYDNSYA--------------NITASSR-HVLDFPVPNQFKFQISNKSTPYTFNTMEI 61 
CCK70212       1 MLDYMDYVQRTFETATGW----HRDRGYA--------------NVGSGGAlACSSSRCPSGSSCRLHTRATRHSFNTLDL 62 
7BTX_L        62 STR------SRINGSLSYLYSDAQqLEKFMRNSTDIPLQDATETYRQ------LQPnlnfsvssa--------------- 114
CCF60433      62 DRN------NKINGSLTYLYTDADnVEKIVKSSSQVLLQDATETYRH------IQP------------------------ 105
CCC70664      63 TARqnnrhpQRINGYLTYLYTNVKnLHDAIHNSNDISLQDATQTYKH------VQPs----------------------- 113
XP_003671683  63 TTKqnnlqnKKVHGFLTYLYTNMEnLHEIILSSSKINLQDATQTYKH------IHPsyyk-------------------- 116
A7TNL0        56 STN------KVINGSITYLYTDAKgLDKLIKDSHNINIQSIVETYNHhcktlnI-------------------------- 103 Vanderwaltozyma...
CCE65418      80 TTK------QSINGSFAYIYTNAEnLDNIVKNTSNVNLLDIVDTYQV-------NN------------------------ 122
CCE94206      63 STR------NVFNGSLTYLYTDADnLEKIVSDSGSIDLQNVTETYRY------FQPf----------------------- 107
C5E1U4        62 FSR------KIFNGSMTYLYTDAEnMDKLVHDSNSISLQDVTDTYRY------VQP------------------------ 105 Zygosaccharomyc...
AQZ11016      62 FTK------KIFNGSMTYLYTDADnMDIFVQNSNSTTLQDVTETYRY------VQP------------------------ 105
CCK70212      63 ASW------GNVSGALTYLYTDCAaVEELVGGSEAVRLQHATETFRD------VAGkhpttyhdaakqqndaqetqlepe 130
7BTX_L       115 -------ntlssdnttVDNDKKLLHDSKFVKKSLYYGRMYYPSSDLEAMIIKRLSPQTQFMLKGVSSFk----ESLNVLT 183
CCF60433     106 ----------------FFSRQLDDITHAFEPKSLYYGRIYYPKSTLEAMIIKRFNVNTQLVVKCISNMy----SDMNIML 165
CCC70664     114 ----------------FNTKKKSIVDHEGENASLYYGRIYYPTSDLEAMVMKRLKRNSQLTFKWLSSPi----NNLNILT 173
XP_003671683 117 -------------rrrGHNYFDNGIEKSKDNLSLYYGRMYYPSSDLEAMIIKRLNRNNQMTLKWLSSSa----YNFNIMT 179
A7TNL0       104 ------------------------NKQNVDFKSLYYGRMYYPNSHLEGMIIKKFTTNTQVVLKWVSSF-----NSCNIIT 154 Vanderwaltozyma...
CCE65418     123 ----------------KKTRGKYSSKYQGKIKSLYYGRMYYPSSFLEAMVIKKFNPSTQVIVKWISSS-----NNCNIVT 181
CCE94206     108 ---------------yNNHKLAAPTDGKTVGKSLYYGRMFYPNSNLEAMLIKTLDPHKQLKIKWLSTF-----DDFNILT 167
C5E1U4       106 ----------------YY-THKPSSNGDNHVRSLYYGKMSYPSPNLEAMLIKRLNESTQLTLQCVSSF-----NGFNILT 163 Zygosaccharomyc...
AQZ11016     106 ----------------YH--SHAHASSLNHMKSLYYGRMSYPCPNLEAMLIKRLNETTQLTLKCVSSF-----NGFNILT 162
CCK70212     131 danygsdpvalhaspaASHPAAQDARQCAWPHSLYYGRIYYPSSTLEAMIVRRCTPFSQLVVKCISSAtpaptPQFNIAT 210
7BTX_L       184 CYFQRDS--HRNLQEWIFSTSDLLCGYRVLHNFLTTPSKFNTSLYNNSSLSLGAEFWLGLVSLSPGCSTTLRYYTHSTNT 261
CCF60433     166 LNWQRTK--GQNLQEFVVSSNGLLCGYRVLHNFISSPSKFNNSLYNNSSMSLGGEVWLGLSTLTPGCSTTLRYCTNSANT 243
CCC70664     174 IYWQLKTrqDRNLHEFIYSTNDSLCGYRVLHNFVSGSSKFNNSLYNNSSLSVGGEVWLSLKSHNPGGSTSIRYCTHSANT 253
XP_003671683 180 LYWQNKSrqNRNFQEFIFSTNDYLCGYRILHNSLSTSSKFNNSLYNNSTLSIGAELWLSLKSMNPGCSTSLRYCTHSANT 259
A7TNL0       155 GYFQKYG--KRNFQELIVSSNDFLCGYRFLHNFIEQPSKLNNSLYNNSYISLGGEFWLAISTLSPTCATTLRYCTHSATT 232 Vanderwaltozyma...
CCE65418     182 GYLQRSN--NRTFQEFVLSSNDFLCGYKLLHHFVESPSKFNNSLYNNSQLSVGAEAWLSVSNLSPTCSSTLRYCTHSAST 259
CCE94206     168 CYWQRDT--GRDSQEVIFSTNDLLCGYRFLHNFIGKPSKMKNSLYNNSSLSLGAELWLGLITLSPGCSTTLRYCTHAPNT 245
C5E1U4       164 GYWQHDT--GRNRHEVIMSTNDLLCGYRYLHNFLGTPSKLKTSLYNNFSLSLGGEVWLGIVTLSPGCSTTLRYCTHSPTT 241 Zygosaccharomyc...
AQZ11016     163 GYWQHDT--GKNRHEIIMSTNDLLCGYRFLHNFVGTPSKFKTSLYDNSSLSFGAELWLGIITLSPGCSTTLRYCTHSPNT 240
CCK70212     211 LYWQRDK--DHSFQEWILSSNDALLGYRVLHNYVGGGSKFNNSLYNNSVLSFGFEAWLGLVSLNPACSVSARYATHAANT 288
7BTX_L       262 GRPLTLTLSWNPLFGHISSTYSAKTGTNSTFCAKYDFNLYSIESNLSFGCEFWQKKHHLLETNKNNNDKLEPISDELVDI 341
CCF60433     244 GRPLTLTFSWNPLFGHISSSYTAMTTSNSTISAKYDFNLFSIDSNLSFGCEFWKSGSKINDPDLESSFENVATFETTTSN 323
CCC70664     254 GRPLTLTFSYNPLFGHISSTYAAKTGLNSTFCTRYDFNIYSIDSNLTFGWEFWKNNSDNSKLKEPDTNVNSLSGNSS--- 330
XP_003671683 260 GRPLTLTVSYNPLFGHISSSYSAKTSLSSTFCTRYDFNIYSIESNLSFGWEFWGTGKQKESLLPPNTINNTSIVPNMAIL 339
A7TNL0       233 GRPLTLTLSFNPLFGHLSSTYSAKTSSNSAFCVQYDFNLYSIDSNLSLGCELWKQNELIQNVSQEKSKKQEIQVPPNFYN 312 Vanderwaltozyma...
CCE65418     260 GRPLMLTCSLNPIFGHLSSTYSAKTTSNSTCCVKYDFNLYSMESNLSLGTEIWKNNSEFTSNKIKVQNTHIERNTSDISN 339
CCE94206     246 GRPLTLTLKWNPIFGNLSSSYSAKTSSNTTVCAKYDFNLYSIDSNLSFGVELWRRGNSAKAMSQYQDVSQTFGKDENLMY 325
C5E1U4       242 GRPQTLTLTWNPLFGHISSTYTAKTSSSSTFSTKYDFNLYSIESNLSFGCEFWRRGYQESSPQLQEQINGHASEPKDRIM 321 Zygosaccharomyc...
AQZ11016     241 GRPLTLTLTWNPLFGHISSTYTAKTSSSSTFSTKYDFNLYSIDSNLSFGCEFWRSGSEEKPYEGDNHQGDSKMYHHMMTS 320
CCK70212     289 GRPLTLTVSWNPLFGHVSSTYAARTTTNTAFTAKYDFNIYSIDSNLSFGCEIWRRGRQTGLPGASVPEKRPARGVPIEWP 368
7BTX_L       342 NPNSRATKLLHENVPDLNSAvndipstldip-----------vhkqkllndltYAFSSSLRKIDEERSTIEKFDNKINSS 410
CCF60433     324 TSDAGPVTTRHYSTVENDVLslsphee-------------------rllndltDTFSESLQKMDKEKSIIERFKNKFRNE 384
CCC70664     331 -------LEVSPLINTSQQKlln---------------------------dltYTFSSSLEKIDKEKTAIEKFQKKINES 376
XP_003671683 340 NNVNGTIPNNISDDGIILDEhfsegtrksqilptmelspttsesqqkllqdltYTFSSSLEKIDKEMTLIDKFQNKFEMT 419
A7TNL0       313 NNSNDA-KQKRILNDLNT------------------------------------TFESSLKKIDKERAVIENFETDLYNK 355 Vanderwaltozyma...
CCE65418     340 KIPNSDKFTISEEYHSISNDkqkkv-----------------------lndlnATFTSSLQKIDKERSLIENFQNNMYDK 396
CCE94206     326 HHLVPDLSQEQASPQTRKDLvekqql----------------------lndltTAFSSSLRKIDREKTMIEEFQNNLHHA 383
C5E1U4       322 YYHMMAPDSRNSISPRANSPqerql-----------------------ledltIAFSSSLKKIDKEKSMIEQFENRINQS 378 Zygosaccharomyc...
AQZ11016     321 EKDLKAFSNSVPDKNPKADSqqekql----------------------lddltIAFSSSLKKVDKEKSVIKKFENKVSDS 378
CCK70212     369 LDLVHPSVQTQKLLDDLTH-----------------------------------TFSASLQKLDEERSIIEQFENNFNAA 413
7BTX_L       411 IFTSVWKLSTSlRDKTLKLLWEGKWRGFLISAGTELVftrgfqeslsddekndnaisisatdtengnipvfPAK-FGIQF 489
CCF60433     385 NFTQVWKFATSlRDRNLKILWEGKFREFLISAGTELVfsrdvliskgfd----------dsnnaqnnnskiPAK-FGIKI 453
CCC70664     377 NFTNVWKFSTSlKDKNLKIKWEGKFKGFLLSAGTELYstssiiqdingqtn-------fkhqknervmplyPGK-FGFQL 448
XP_003671683 420 NFTSVWKFSTSlRDKNLKAKWEGKFRGFLVSIGTELFtttpepktnsskpa-------fkhennnsvlplhPAK-FGIEI 491
A7TNL0       356 DFTSVWKFSTSlRDKNLCILWDGKFKGFLLSAGTELIrintnnenn-----------------sqslvkfyPAK-LGLQL 417 Vanderwaltozyma...
CCE65418     397 NFTSVWKFSTSlREKNLRILWNGKYKDFILVAGTELLqqenkdettsd-------------fnkngfpykfVTArLGFQI 463
CCE94206     384 NFTSVWKLSTSlRDANLKVLWEGKFKGFLISAGAEVSkaspllqss-----------------sseklpsyLSK-FGVQL 445
C5E1U4       379 NFTSVWKLSTSsKDKNLRLLWEGKFKGFLLSAGTEFCktnprneinev-------------pstenkltfyPNK-FGIQL 444 Zygosaccharomyc...
AQZ11016     379 TFSSVWKLSTSlRDKNLRVLWEGKFKGFLLSAGADFCnndpkaeltel-------------qtdekklsiyPKK-FGVQL 444
CCK70212     414 NFTNVWKMSTSlMDRNLRVLWECKFKGFLLSMGTELLaspssdqvan---------------trkpfpieiPKQ-FGIMV 477
7BTX_L       490 QYS 492
CCF60433     454 QYS 456
CCC70664     449 QYS 451
XP_003671683 492 QYS 494
A7TNL0       418 QFS 420 Vanderwaltozyma polyspora DSM 70294
CCE65418     464 QYS 466
CCE94206     446 QYS 448
C5E1U4       445 QYS 447 Zygosaccharomyces rouxii CBS 732
AQZ11016     445 QYS 447
CCK70212     478 QYS 480
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