Conserved Protein Domain Family
SFT1

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COG5161: SFT1 
Pre-mRNA cleavage and polyadenylation specificity factor [RNA processing and modification]
Statistics
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PSSM-Id: 227490
Aligned: 3 rows
Threshold Bit Score: 1581.9
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
19112233    1 MSTIFQDLVDSTVIKNAVQGQFTSLVSNNLVVSKVNslhLFEIEKIQKDESSFPLDDSLQNEFSTSIIDESQAFMETNMH 80   fission yeast
19074861    1 MNYLYSQESLWNATEGCSAGLFIP-RTCSFLTYNGN-----AVRLWKYSSGLVLVKEHMLLEKVCQVEKY-RISSEQDGL 73   Encephalitozoon c...
6320507     1 -MNVYDDVLDATVVSHSLATHFTTSDYEELLVVRTN---ILSVYRPTRDGKLYLTDEFKFHGLITDIGLIPQKDSPLSCL 76   baker's yeast
19112233   81 LIRTNEQTTYVLRLVSQVKVFGTITeISALKGKGSNgcdllIMLTDYAKVSTLEWDMQSqsfvTNSLHYYEDVKSSNICS 160  fission yeast
19074861   74 VLLFHRAKISLARFDSQANEFRTIS---------------------LKFFEKDEFDIRD-----------EDIGN----- 116  Encephalitozoon c...
6320507    77 LLCTGVAKISILKFNTLTNSIDTLS-LHYYEGKFKG-----KSLVELAKISTLRMDPGS----SCALLFNNDIIAFLPFH 146  baker's yeast
19112233  161 SHTPTQLLVDPDSDCCLLRFLTDMMAIIPYPANEDLDMEEAAIENSKISssyayKPSFVLASSQLDASISRILDVKFLYG 240  fission yeast
19074861  117 --------VRISVDLGMFQMSKRHFSIFP-------------LFPGAFS-------AKVFKFIEIDGKIKNPIDFVFLEN 168  Encephalitozoon c...
6320507   147 VNKNDDDEEEEDEDENIDDSELIHSMNQKSQGTNTFNKRKRTKLGDKFT-----APSVVLVASELYEGAKNIIDIQFLKN 221  baker's yeast
19112233  241 YREPTLAILYSPEQTSTVTLPLRKDTVLFSLVTLDLEQRASA--V----ITTIQSLPYDIYASVSIPTplgGSLLLGGNE 314  fission yeast
19074861  169 YSIPTVCLVYD---SLPRKYTILRN-YNAIVFSIDLGAGRFH--V----IDEFLVPPRTFRVTCAGPV-----LLFISHN 233  Encephalitozoon c...
6320507   222 FTKPTIALLYQPKLVWAGNTTISKLPTQYVILTLNIQPAESAtkIesttIAFVKELPWDLHTIVPVSN---GAIIVGTNE 298  baker's yeast
19112233  315 LIYVDSAGRTVG-IGVNSYYSKCTDFP-LQDQS--DFNLELEGTIAIPLTSSKTET------PFVVLVHTSGQFFYLDFL 384  fission yeast
19074861  234 SILIRSTSSSYT-IPLNRMSEAYGGNKiVEDIVlsDVNCFSRGN------G--CLI---------FNG--NGDRYRLRIS 293  Encephalitozoon c...
6320507   299 LAFLDNTGVLQStVLLNSFADKELQKTkIINNSslEIMFREKNTTSIWIPSSKSKNggsnndETLLLMDLKSNIYYIQME 378  baker's yeast
19112233  385 LDGKSVKGLSLQALDLEINDDFLKSGITCAVPAGEN------LVFLGSQTTDSYLLRWSRRTTNEEVRLDE----GDDTL 454  fission yeast
19074861  294 MDIKRIIG---ASLEFEG----KGPAVSCVGHVNNL------LFVGSVGDS-SRVFEIKSLLP----RASE----GVGPD 351  Encephalitozoon c...
6320507   379 AEGRLLIKFDIFKLPIVNDLLKENSNPKCITRLNATnsnknmDLFIGFGSGNALVLRLNNLKSTIETREAHnpssGTNSL 458  baker's yeast
19112233  455 YGTN---DAEMDDMLD--IYETDESVGSKRKIAYENGPLRLEICDVLTNIGPITDFAVGKAG----SYSYFPQDNHGPLE 525  fission yeast
19074861  352 EGGT------LSDEYS------KLFGNKEQEVRRQDEEY-AKLFNAGSEARSGEDFALHEVD-----E----IPNIGLLN 409  Encephalitozoon c...
6320507   459 MDINdddDEEMDDLYAdeAPENGLTTNDSKGTVETVQPFDIELLSSLRNVGPITSLTVGKVSsiddVVKGLPNPNKNEYS 538  baker's yeast
19112233  526 LVGTAGADGAGGLVVFRRNIFPLIAGEFQFDGCEALWTVSISGKLRNMKsriqaqysnpeLETYLVLSKEKESFIFLAGE 605  fission yeast
19074861  410 GVVMK-SDSEAAFAVEG--LEPCVCTVSSTIPLEIVKSQKIRRYLYCSR-----------ALDFYILGRVSDTRVFRWSE 475  Encephalitozoon c...
6320507   539 LVATSGNGSGSHLTVIQTSVQPEIELALKFISITQIWNLKIKGRDR---------------YLITTDSTKSRSDIYESDN 603  baker's yeast
19112233  606 TFDEVQHSDFSKDSKTLNVGSLLSGMRMVQICPTSLRVYDSNLRLTQLFNFSKKqIVVSTSICDPCIIVVFLGGGIALYK 685  fission yeast
19074861  476 EGLLEVSGEYTRSVNTLLFVEFG--NEVVQVTPSYCLRMDQDLRMLGRVEFASR-AIEARTVRDGLFLAVRDSEKRLTFY 552  Encephalitozoon c...
6320507   604 NFKLHKGGRLRRDATTVYISMFGEEKRIIQVTTNHLYLYDTHFRRLTTIKFDYE--VIHVSVMDPYILVTVSRGDIKIFE 681  baker's yeast
19112233  686 MDLKSQR-LIKTDLQNRLSDVKTASLVSPDSsalfaklftynetlNAKGQIANGMNDSASETDLDIqpnhKTSNNDQMGY 764  fission yeast
19074861  553 DREMNMA--FSIPSVTCFADAKNKIFVLSDY---------------SLGIFDIDKRISQLLPCSVK----GLPYAIRFSP 611  Encephalitozoon c...
6320507   682 LEEKNKRkLLKVDLPEILNEMVITSGLILKS--------------NMCNEFLIGLSKSQEEQLLFT----FVTADNQIIF 743  baker's yeast
19112233  765 DQSVSADDVPEVDntivteknvsNLDQeslekhpilfaLTDEGKLKVYNLADfsllmecDVFDLPptlfngmesertyfn 844  fission yeast
19074861  612 EASPAMDLAGEED-----------DS------------VTEISMSLTDNKIL-------MLFRLR--------------- 646  Encephalitozoon c...
6320507   744 FTKDHNDRIFQLN----------GVDQ-----------LNESLYISTYQLGD-------EIVPDP--------------- 780  baker's yeast
19112233  845 kessqELVELLVADLGDDFKEPHLFLRSRLNEITVYKAFLYSNTDKHKNllafakvpqetMTREFQANVGTPrdaeSTME 924  fission yeast
19074861  647 -------GNYMVAYESLDLMK--LFDNSLSSEIVFFKTHLPRHVSFNLA----------------------P-------D 688  Encephalitozoon c...
6320507   781 -----SIKQVMINKLGHDNKEEYLTILTFGGEIYQYRKLPQRRSRFYRN-----------VTRNDLAITGAP----DNAY 840  baker's yeast
19112233  925 KKASSSVDHLKMTALEVVGnHSAVFVTGRKPFLILSTLHSNAKFFPISsNIPILSVAPFHAhhapQGYIYVDENSFIRIC 1004 fission yeast
19074861  689 IKAFHSVG--DMVFIKAVP-HMFMIPTDKGHFLCRSRYTLSSIAMHRG------QLIQLSK-----GYLMVCNVLGVGAS 754  Encephalitozoon c...
6320507   841 AKGVSSIERIMHYFPDYNG-YSVIFVTGSVPYILIKEDDSTPKIFKFG-NIPLVSVTPWSE----RSVMCVDDIKNARVY 914  baker's yeast
19112233 1005 KFQEDFEYD-NKWPYKKVSLG------KQINGIAYHPTKMVYAVGSAVPIEFKVTDEDGnEPYAITDDNDYLPMANTGSL 1077 fission yeast
19074861  755 QYVFGNGLVgKKNRVLRTPKH-------------IECAGRYMVVGSCEEAGFSPKGEKD--SGIPVDT-------YRFYV 812  Encephalitozoon c...
6320507   915 TLTTDNMYYgNKLPLKQIKISnvlddyKTLQKLVYHERAQLFLVSYCKRVPYEALGEDG-EKVIGYDENVPHAEGFQSGI 993  baker's yeast
19112233 1078 DLVSPLTWTVIDSYEFQQFEIPLSVALVNLEVSETTKLRKPYIAVGTSITKGEDIAVRGSTYLFEIIDVVPQPGRPETRH 1157 fission yeast
19074861  813 DLYSEK-YEHIDTYELDENEYVFHIKYLILDDMQGNYGKSPFLLVCTTFIEGEDRPARGRLHVLEIISVVPSLESPFKDC 891  Encephalitozoon c...
6320507   994 LLINPKSWKVIDKIDFPKNSVVNEMRSSMIQINSKTKRKREYIIAGVANATTEDTPPTGAFHIYDVIEVVPEPGKPDTNY 1073 baker's yeast
19112233 1158 KLKLVTREEIKGTVAVVCEVDGYLLSGQGQKVIVRALEDEDHLVGVSFIDLGSYTLSAKCLRNLLLFGDVRQNVTFVGFA 1237 fission yeast
19074861  892 KLKVLGIEKTKGSIVRCEEVRGKIALCLGTKIMIYKIDRSSGIIPIGFYDLHIFTSSISVVKNYILASDIYRGLSFFFFQ 971  Encephalitozoon c...
6320507  1074 KLKEIFQEEVSGTVSTVCEVSGRFMISQSQKVLVRDIQEDNSVIPVAFLDIPVFVTDSKSFGNLLIIGDAMQGFQFIGFD 1153 baker's yeast
19112233 1238 EEPYRMTLFSKGQEALNVSAADFLVQGENLYFVVADTSGNLRLLAYDPENPESHSGERLVTRGDFHIGNVITAMTILPke 1317 fission yeast
19074861  972 SKPIRLHLISSSEPLRNATSTELLSTGNELSMLCCDAKGTIHGYTYSPNNIISMDGARLVKR-------AEIKTNLG--- 1041 Encephalitozoon c...
6320507  1154 AEPYRMISLGRSMSKFQTMSLEFLVNGGDMYFAATDADRNVHVLKYAPDEPNSLSGQRLVHCSSFTLHSTNSCMMLLP-- 1231 baker's yeast
19112233 1318 kkhQNAEYGYDTGDDFSCVMVNSDGGLQMLVPISDRVYRRLNIIQNYLANRVNTIGGLNPKSYRLITSPSNLTNPTRRIL 1397 fission yeast
19074861 1042 ---RLSSFGAGFKKNSIMFYSRSN-MLIHVSGIDDAHYLKLLGVQTAIMAHLKSVFGLNQRDY-LNSDIHLHSLSLKSPI 1116 Encephalitozoon c...
6320507  1232 ---RNEEFGSPQVPSFQNVGGQVDGSVFKIVPLSEEKYRRLYVIQQQIIDRELQLGGLNPRMERLANDFYQMGHSMRPML 1308 baker's yeast
19112233 1398 DGMLIDYFTYMSVAHRHEMAHKCGVPVSTIMN-DLVELDEALSYM 1441 fission yeast
19074861 1117 VLHILNLFSYFDMSTQESVSSSA-RIDRKEIS-DMIASLNLL--- 1156 Encephalitozoon cuniculi
6320507  1309 DFNVIRRFCGLAIDRRKSIAQKAGRHAHFEAWrDIINIEFSMRSL 1353 baker's yeast
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