Conserved Protein Domain Family
CopL_fam

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NF033807: CopL_fam 
CopL family metal-binding regulatory protein
The founding member of this family was shown to be involved in the copper-responsive expression of a multicopper oxidase copA encoded downstream. The regulatory function likely involves copper-binding, but activity as a DNA-binding transcriptional regulator was not demonstrated directly.
Statistics
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PSSM-Id: 468190
Aligned: 92 rows
Threshold Bit Score: 48.8727
Created: 11-Oct-2024
Updated: 3-Dec-2024
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_056102616   4 LLRLLLCVGLILNGSAYAVASTQMQLSHLSA---------TMGAAAIAQTS----------CHDGMTdSGMTHDGMahdg 64  Lysobacter sp. ...
WP_057631672   6 WLPLLLICVLAAEGVLGAWAGARMAMETVAS---------VATDTGAGavd--------pdCEPAKPvLAQTHGDHg--- 65  Stenotrophomona...
SOU01483       7 LLRMFLILVLCADGILSAQATTRMAVRHIPPpgavngthsVHGGARVNERAkis-----ndCNKIRPgGKQAGQGD---- 77 
BAV97969       7 LLRMLLILVLCADGIFAAWASTRMAVAELGHg--------ASSSVSHHGASgltktagqrlAQDDGA---GAPVPD---- 71 
WP_097120559   7 LLRVLLIFVLCAEGVLGAWASTRMAVGAIAH-----------AEASAAAGQgni-----edCEDGSA-ADRQQNDG---- 65  Pseudoxanthomon...
WP_058835668   7 LLRILLSMLLCLNGGTALWASTGMALDPSHM---------------SVAGDeaa-----vdAHADHA-PAGADDTG---- 61  Luteimonas abyssi
KGM56285       7 ALRCLLIVAFCLDGGASLWKASQMAAHMASKss------nATASTVSDPVSgta-----atSAQGCEsPGLAVSTS---- 71 
WP_055901626   7 LLRCLLIVAFCLEGTLSLWASSAMAAEGAVAa-------tTRIGAESNDALavd-----ldCEDDSS-----HGQG---- 65  unclassified Ly...
WP_056174918   7 LLRCLLIVAFCLEGTLSLWSSSVMATEGVAA----------AVSAEAAAAVvad-----edCEEQTP-----HREG---- 62  unclassified Ly...
WP_036193667   7 LLRCLIVLAFCLDGTAMAWQKSAMAAGAVHH---------GHAATGGHEAAghgpdmdtvaVLDQDHaDTTAPVPT---- 73  Lysobacter
WP_056102616  65 mhmagmdhdgasmpaghsgHAPDAt-sPDC-CKSP---TCTCSCLQPAPATAI-AfALGGAHIGHAMIAQPMPVDHDAPA 138 Lysobacter sp. ...
WP_057631672  66 ------------------rGTMPAh-hADCtCVDSt--GCECVCVLVLYPPTSvKlFAGTHPPVSLDTALPVLELPASK- 123 Stenotrophomona...
SOU01483      78 -------------------QNDHQ-----CdCSTT---SCDCSCVLTFFAGRVpViFAAQHDLTSTYLPTPELPPLRRQV 130
BAV97969      72 -------------------PSPHH---DDCdCSSLs--GCACSCMLTFFPGRNtPlFCAQHTLASMHLAPPLLPPVRHR- 126
WP_097120559  66 -------------------RTAHQ----GCdCGAQa--FCGCSCMLTFYPPGGsVlFSAQHALASVYLGTLRTHSVRNEI 120 Pseudoxanthomon...
WP_058835668  62 -------------------ADPHRhvgNDCdCGAGmiaSCACSCAYPAGFAVMsVpFAAQH--ARPAATAAYVEIHAPLR 120 Luteimonas abyssi
KGM56285      72 -------------------TNEQH---EDCdCEEAn--GCRCPCAFAVKLLVQrVpFAAQHRLAVQPAIAQEPSTAQIKT 127
WP_055901626  66 -------------------GSPHR----DCdCGTGs--GC-CACAFPVLAVAHgVpFAAQHRLAEQPPIPAPASVIPAAA 119 unclassified Ly...
WP_056174918  63 -------------------GSPHR----DCdCGTGs--GC-CACAFPVLAVIHsVpFAAQHRLADQPVALAPVSAAPAAA 116 unclassified Ly...
WP_036193667  74 -------------------DAMHE----DCdCSET---GCDCACGFGTFALARgIpHVDTLWIGFVPVSGDLTAARKGVA 127 Lysobacter
WP_056102616 139 -LHSPIRPPIA 148 Lysobacter sp. Root667
WP_057631672 124 -LSRVFRPPIA 133 Stenotrophomonas humi
SOU01483     131 --SRLFRPPIG 139
BAV97969     127 -LSALFRPPIA 136
WP_097120559 121 --SPVFRPPIA 129 Pseudoxanthomonas wuyuanensis
WP_058835668 121 gTGSIFRPPIG 131 Luteimonas abyssi
KGM56285     128 --SAVFRPPIA 136
WP_055901626 120 --TGVFRPPIV 128 unclassified Lysobacter
WP_056174918 117 --TGVFRPPIA 125 unclassified Lysobacter
WP_036193667 128 --SSLFRPPIG 136 Lysobacter
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