Conserved Protein Domain Family
SYS1

?
pfam09801: SYS1 
Integral membrane protein S linking to the trans Golgi network
Members of this family are integral membrane proteins involved in protein trafficking between the late Golgi and endosome. They may also serve as a receptor for ADP-ribosylation factor-related protein 1 (ARFRP1). Sys1p is a small integral membrane protein with four predicted transmembrane domains that localizes to the Trans Golgi network TGN in yeast and human cells.
Statistics
?
PSSM-Id: 370705
Aligned: 25 rows
Threshold Bit Score: 139.296
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q7S576        11 GALTELPPLKILSQIAALQAIYYTAALVLMFFTAAVAGNPFTLDLVFGWEAVRGDNTQGWLNGFIWCLVgGLVLPLSLTA 90  Neurospora crassa
Q55E69         3 YKYNAWDPKLIIGQILSIQCLYYILLAGILYLLDSMFSSSLSLEQMFEYQSINTHSQSGRVVMTAFLIN-SLFGSFCLKY 81  Dictyostelium d...
Q9SSD6         3 YGTAVWDPWLIVGQIICLQCSYYLTLGLFTMVFLGLRVPRLSLVYFFDYATLTTSTFTGWSVIASFLFS-SLAGAVYMIF 81  thale cress
Q7PYJ7         5 FRNTQWDPYLLVAQIVAMQALLYVSLGTIMYVMDFFAEANHTLDHIFEYHEIHVTDLGGRLVIVAFILN-SLVGAGLLWF 83  Anopheles gambi...
Q1HPQ8        11 FRYTQWDPCLIIFQIVAMQSVMYLSLSLLVAIMQDLTGSTRTLDHLFEYHELHIVDNEGRAVILAFVFN-AVIGAFALWM 89  domestic silkworm
Q9VHP1         6 FRNTQWDPTLLSSQIVSMQFCVYFTLGLLVFVANKLSGDNYSLDHLFEYHEIHIYDMGGRLVICAFVLN-AFLASLALWC 84  fruit fly
A7S6Y0         5 FRTNVWDPVLIISQIIAIQCTFYISLGVWVLIVDYWSGSIHSLDQFFAYKELDISSLKGKLLMIAFCLN-SLTGAMALWF 83  starlet sea ane...
1_pfamImport   1 FRSYIWDPVLILSQILLMQCIYYSFLGLWLAGVDALVHTSRSLDQIFSYEVLGFATMQGRLSMMAFILN-SLTCALGLWF 79 
Q1RMQ3         5 FRSYVWDPLLILSQIVLMQTVYYGSLGLWLALVDGLVHSSPSLDQVFDAEILGFSTPPGRLSTMSFVLN-ALTCALGLLY 83  domestic cattle
Q28EU0         5 FRSYIWDPVLIISQILLMQLIYYSCLGLWIAVLDLVVHYSPSLDQIFNCGILGFSSVPGRVSMMAFILN-SLTCALGLLY 83  tropical clawed...
Q7S576        91 IVQRSKLILDFALTTHFIHLVIVTLYTtpdHTLPrHTAWWLTMAISSLASFLLGSWGCRYRELQPIAF 158 Neurospora crassa
Q55E69        82 IVERSKKCLDHSATVTFIHFIIVWIV----SGFPkTVVWWAIQLIGMVIMAMIGEYLCMRKELMDIPL 145 Dictyostelium discoideum
Q9SSD6        82 LVERARKCLDFSATLYIIHLFFCIMY----GGWPsSMAWWVVNGTGLAVMALLAEYLCIKREQREIPM 145 thale cress
Q7PYJ7        84 VVRRTKLCLDFSFTFHFTHLVICWWYN---EAFPsTIGWWMLNAVCAALMCVCSEFLCLKTELKEIPV 148 Anopheles gambiae str. PEST
Q1HPQ8        90 IVGRTKLCLDFSCTYHGLHLIACWYYN---GSFPtTFSWWTLNIACGAIMCVAGEFLCLRTELQAIPL 154 domestic silkworm
Q9VHP1        85 IVRRAKLCLDFSCTFHVLHLLICWWYN---RSFPaNASWWLLNVITGTIMCIGGEFLCLQTEMKEIPV 149 fruit fly
A7S6Y0        84 IVKRAKQCLDFTTTAHIVHLVFCCIY----AGFPfSWTWWLLNIICLALMAVIGEFVCMKTELKAIKV 147 starlet sea anemone
1_pfamImport  80 FIRRGKQCLDFTITVHFFHLIGCWIYN---AQPPaALSWWLVNVACIALTAVIGEYLCMRTELRAIPV 144
Q1RMQ3        84 FIRRGKQCLDFTVTVHFFHLLGCWLYS---SRFPsALTWWLVQAVCIALMAVIGEYLCMRSELKEIPL 148 domestic cattle
Q28EU0        84 FIRRGKQCLDFTVTVHLFHLFGCWIYT---SQLPsSFTWWLLNVVCIALMAVIGEYLCMRTELREIPL 148 tropical clawed frog
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap