Conserved Protein Domain Family
NuoG
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TIGR01973: NuoG 
NADH-quinone oxidoreductase, chain G
This model represents the G subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria while translocating protons, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes related subunits from formate dehydrogenase complexes. [Energy metabolism, Electron transport]
Links
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Statistics
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PSSM-Id: 273904
Aligned: 14 rows
Threshold Bit Score: 738.785
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P57257         4 IYVDSKIYNVNESDNLLQACLSVGINIPYFCWHPLLGSLGACRQCAVTQYDn--------------------FQdrkgrL 63  Buchnera aphidi...
Q9XAR0        24 LTIDGAEISVPKGTLVIRAAEQLGIEIPRFCDHPLLDPAGACRQCIVEVEGq--------------------RK-----P 78  Streptomyces co...
AAH06660      34 VFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEK---------------------APk----V 88  house mouse
Q9ZCF6         4 LIIDGSEIEISEGSTVYQACIQAGKEIPHFCYHARLKIAGNCRMCLVEIEK---------------------SQk----P 58  Rickettsia prow...
Q37373         6 FKVNDFQYTINNKLTLIQACLKNKVDISRFCFHEKLSIAGNCRMCLVEDLK---------------------QVk----P 60  Acanthamoeba ca...
AAO28140      17 IEIDGQNLVVPKGSMIIQAADNAGIPIPRFCYHEKLPIAANCRMCLVDVEK---------------------VPk----P 71  Xylella fastidi...
AAO26882       4 IFVDNEEYNVDKSDNLLQACLSSGINIPYFCWHPVLGSIGSCRQCAVTIYKd--------------------LEdkvgqL 63  Buchnera aphidi...
WP_010919812   4 aKVNGVEVEFEPGMTVLQVAELAGEEIPRFCYHERLSIAGNCRMCLVEVKPg--------------------PPk----P 59  Caulobacter vib...
WP_028853321   4 IEIDGKKVEVAEGSLVMEAARQAGTYIPHFCYHRKLSIAANCRMCLVEVEK---------------------APk----A 58  Ralstonia solan...
WP_010888138   3 VTVDGVPLDLPAGTSGIDAVFAAGRDVPYFCAHSYLSPVGACRMCLVESGSprkgkdgnfeldeqgevkifwFPk----P 78  Deinococcus rad...

P57257        64 IMSCMT--PVTDGAIISI--KSTESEVFRSAIVELLLTNHPHDCPVCEEGGHCHLQDMTVMVKHSMRNYRFKKRTHKNQY 139 Buchnera aphidi...
Q9XAR0        79 MASCTItcTDGMVVKTQL--TSPVAEKAQHGVMELLLINHPLDCPVCDKGGECPLQNQAMSHGQSDSRFEGKKRTYEKPV 156 Streptomyces co...
AAH06660      89 VAACAM--PVMKGWNILT--NSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEgKRAVEDKN 164 house mouse
Q9ZCF6        59 VASCAM--PVSKGMVIHT--DTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAFRYGKGTNRFHENKRSIKDKY 134 Rickettsia prow...
Q37373        61 LASCAI--NVSNSMNIYT--NTLKVKKARESVLEFLLANHPLDCPICDQGGECDLQDQSVVFGSDRGRFYEFKRSVEDKD 136 Acanthamoeba ca...
AAO28140      72 LPACAT--PVMEGMKVRT--RSEKALQYQRSVMEFLLINHPLDCPICDQGGECELQDVSMGYGRSVSRFHERKRVVPDED 147 Xylella fastidi...
AAO26882      64 VMSCMT--SVLDGMIVST--SDKISRNFRKGIIELLMLNHPHDCPICEEGGSCHLQDMTVMAGHTVRRYRFTKRTHKNQY 139 Buchnera aphidi...
WP_010919812  60 QASCAL--PAAEGQEIFT--KTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAVGYGRDDSRYEENKRAVEEKS 135 Caulobacter vib...
WP_028853321  59 LPACAT--PVTAGMKVFT--NSEKAVKAQKSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGKSESRYKEEKRVVFHKN 134 Ralstonia solan...
WP_010888138  79 MAACTM--QATEGMHIKTaaTSEVVAKSQAGMMEFTLLNHPLDCPTCDKGGACELQDRAFEYGYGASRFGFDRRHADKHY 156 Deinococcus rad...

P57257       140 LGP-FI-KHEMNRCIACYRCVRYYNEYADGVDFGVYGSNNNVYFGRIEDGVLESEHSGNLIELCPTGVFTDKTHSKKYnR 217 Buchnera aphidi...
Q9XAR0       157 PIS-TQvLLDRERCVLCARCTRFSNQVAGDPMIELIERGALQQVGTGEGDPFESYFSGNTIQICPVGALTSAAYRFRS-R 234 Streptomyces co...
AAH06660     165 IGP-LV-KTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNVIDICPVGALTSKPYAFTA-R 241 house mouse
Q9ZCF6       135 MGP-LI-KTAMTRCIQCTRCIRLANDIAGIEEIGAINRGEHMEVTSYLEQTLDSEISGNMIDICPVGALNSKPYAFKA-R 211 Rickettsia prow...
Q37373       137 CGP-LI-KTIMNRCIHCTRCVRFSNEVAGVNILGVTGRGSKMEIGFYIENLMRSELSGNVIDLCPVGALTSKPFAFTS-R 213 Acanthamoeba ca...
AAO28140     148 IGP-LV-ATEMTRCIQCTRCVRFTADIAGTYELGGMYRGENLQIGTYDGKPLITELSGNVVDVCPVGALTNKVFQFRA-R 224 Xylella fastidi...
AAO26882     140 LGH-FI-THEMNRCISCYRCVRYYKDYSGGTDLGVFGISNNVYFGRYNDGCLESEFSGNLVEVCPTGVFTDKTYSKKYsR 217 Buchnera aphidi...
WP_010919812 136 MGP-LI-KTVMTRCIQCTRCVRFITEVAGSPEIGLISRGEDVEITTYLGAAVTSELSANVIDLCPVGALTSKPYAFEA-R 212 Caulobacter vib...
WP_028853321 135 VGP-LIsMEEMTRCIHCTRCVRFGQEVAGVMELGMLNRGEHSEITTFVGQTVDSELSGNMIDLCPVGALTSKPFRYSA-R 212 Ralstonia solan...
WP_010888138 157 PLSdFV-ILDQERCIHCKRCVRYFEEVPGQEVLDFIERGGHTFIDTQEGG-LPTGFSGNITDICPVGALLDNVARFRG-R 233 Deinococcus rad...

P57257       218 KWDMQYAPGICHNCSVGCNISIGERYGEIRRIENRYHENINHYLICDLGRFGYSHTNLNTRPKKPTYVNKYNDLNVLNFN 297 Buchnera aphidi...
Q9XAR0       235 PFDLISSPSVCEHCSGGCATRTDHRRGKVMRRLAANEPEVNEEWICDKGRFGFRYAQQRDRLTTPLVRNAEGELEPASWP 314 Streptomyces co...
AAH06660     242 PWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ-RLTEPMVRNEKGLLTYTSWE 320 house mouse
Q9ZCF6       212 KWELKHTASIGVHDAEGSNIRIDSRADEIMRILPRVNEAINEEWLSDKNRFCYDGLKYQ-RLDHPYIR-KNGKLVEVSWS 289 Rickettsia prow...
Q37373       214 PWELKSYNSIDVLDSLHSNIRVDIRGTKIMRILPRVNSELNEDWITDKIRFSYDSFRRQ-RLYDPMVK-ISGSFLKIGWK 291 Acanthamoeba ca...
AAO28140     225 PWELMAYQSLGYHDAMGSNLFLHVRQGEVLRTVPRDNEYVNECWLSDRDRYSHQGLYAADRAVKPLKK-VGDQWLEVSWA 303 Xylella fastidi...
AAO26882     218 KWDMQYAPSICQHCCVGCNISVGEKYGKISRIENRYHNAINHYFLCDLGRFSYDYSNVDERLTYSIYRSQNKTKIINDVN 297 Buchnera aphidi...
WP_010919812 213 PWELKKTESVDVMDALGSSIRVDARSAAVLRVLPRINDEVNEEWISDKTRYAVDGLGRQ-RLDRPYVR-VGGKLKPATWA 290 Caulobacter vib...
WP_028853321 213 TWELARRKSVSPHDGLGANVIVQTKNQRVMRVLPLENDAINECWLSDKDRFAYEGLNSDERLTQPMLK-QGGQWQTVDWT 291 Ralstonia solan...
WP_010888138 234 NWEYDHTPTTCTLCPVGCAITVDARNGRLERIVGRENRDVNEIWLCDAGRFGHTFASE-GRLTRPLIRE-NGRLREADWD 311 Deinococcus rad...

P57257       298 EAIKIGVDFFKRy------KRVIG--VGSARSSIENNFALQElVGK----ENFSNGMSNKEKEc-iKSILEFLKNnyi-- 362 Buchnera aphidi...
Q9XAR0       315 EALQIAAQGLLAs-----rGRTGV--LTGGRLTVEDAYAYSKfARValdtNDIDFRARVHSAEe-aDFLAAHVAGrgrdl 386 Streptomyces co...
AAH06660     321 DALSRVAGMLQNfe----gNAVAA--IAGGLVDAEALVALKDlLNKvd-sDNLCTEEIFPTEGagtDLRSNYLLN----- 388 house mouse
Q9ZCF6       290 EAFKTIMDKIKSvk----pEKIAA--IAGSIVSVEAMFMLKIlLQKlg-sNNYTVNQFNYKIDt-sE-RGNYLFN----- 355 Rickettsia prow...
Q37373       292 KAMLFIKKFFCNflgfnhsSFIPLrgYIGDYLDLETIYTFKK-FLLln-gSNFFLPSSSYN-----DLTALYSFN----- 359 Acanthamoeba ca...
AAO28140     304 EGVSAAA----EilsahrgDALGV--LVHPATSNEEGALLARlAAGlg-tGHLDHRIFNRDfs--dVAVAEPFA------ 368 Xylella fastidi...
AAO26882     298 KTIDKLAMKFKKs------SKIIG--IGSCRASVESNFSLQKlVGS----ENFYLGISQKEYDc-lMLIKDILKDnqi-- 362 Buchnera aphidi...
WP_010919812 291 EAFAAIAAKVKSta----pERVGV--IAGDLQDAESLKATKDlFTAlg-vKNLDSRQDGSALGa--gPREGWLFN----- 356 Caulobacter vib...
WP_028853321 292 TALEYVANGLNAikrdhgaEQIGA--LASPHSTLEELFLLQKlVRGig-sDSVDFRLRQSDFs--aKPTGAPWLG----- 361 Ralstonia solan...
WP_010888138 312 EAIAAMRRGLSGih----pSQLGL--FIAADSTLEEGMALERfAAQlg-aGNVDHWPRHPVQLt-aPA------------ 371 Deinococcus rad...

P57257       363 -----------yiPSLKEIESYDVILVLGEDLTQTSSRVALAVRQAVKKKVqDIKNLYGIPKWNTSSNIHIsekfkNSLY 431 Buchnera aphidi...
Q9XAR0       387 ggssrtesgggagVTYTSLEKAPAVLLVGFEAEEEAPGVFLRLRKAWRKHGqKVFSLATHATRGLEKAGGT-----LLPA 461 Streptomyces co...
AAH06660     389 -------------TTIAGVEEADVVLLVGTNPRFEAPLFNARIRKSWLHND-LKVALIG-SPVDLTYR----------YD 443 house mouse
Q9ZCF6       356 -------------TTIVGVEKADLCLLIGANTRQIAPILNSRIGRRVRIGA-LKVVRIG-IGHNQTYK----------IQ 410 Rickettsia prow...
Q37373       360 -------------TPLTRLDEGDFCILLDVNLRVELPIVNSRIKQLVSKKM-LPVFVLG-FYSNFNYF----------VK 414 Acanthamoeba ca...
AAO28140     369 -------------LPLAEIGNADLVVLFGSNIRQELPLLHARLRKAVTCNG-AKVYAVNPVDFDFTFSLTG-----KSIV 429 Xylella fastidi...
AAO26882     363 -----------hvPTLREIEKSDVIFLLGEDVTKTSPLIALSIRQSIKGQVkTQDVSKNIPIWHADAVKNSfrnnkNKLF 431 Buchnera aphidi...
WP_010919812 357 -------------STIAGIENADVVLFVGANPRLEAPVLNARFRKQWLAGK-TRFGVIG-EQADLTFD----------YD 411 Caulobacter vib...
WP_028853321 362 -------------MPIADVSLLQRTLVVGAFLRKDHPLLAARLRQGGKKG--AQLSVIGAGGEDLLMPA-T-----QLLG 420 Ralstonia solan...
WP_010888138 372 -------------ATLTDVAQADALVVIGADLGEEAPVLELRILEALRGG------ILPTEFDHGTAIADL-----RLVE 427 Deinococcus rad...

P57257       432 IMHTHESKLDDISewsY---FASIDkqvnlassiayeidkss-pkvsnldselkekvllISDRLIS--SKKTLIISG--- 502 Buchnera aphidi...
Q9XAR0       462 APGTETEWLDALA---S---GVGLEe--------------------------------gGTQAAEAlrAEGAVIVVGerl 503 Streptomyces co...
AAH06660     444 HLGDSPKILQDIA---S---GRHS-----------------------------------FCEVLKD--AKKPMVVLGss- 479 house mouse
Q9ZCF6       411 DLGNDIKIIEDLA---I---GTHE-----------------------------------YTKAFKE--AKYPMIIVGdg- 446 Rickettsia prow...
Q37373       415 HISNSSKTLLHVL---E---GSHW-----------------------------------LSAKISKkfSSKPIFLIGds- 452 Acanthamoeba ca...
AAO28140     430 PPSQLANALTDAA----------------------------------------------LLNAAKA--AARVVIVVGal- 460 Xylella fastidi...
AAO26882     432 ITNLMNSSLDDIAdesY---YASTFdqvllgaevykcisnncisnvtllkqdllscakrIATALTL--SKCPLIISG--- 503 Buchnera aphidi...
WP_010919812 412 YLGAGAKTLSGLA---K---SKN-D----------------------------------FVAALKA--AERPAIIIGqg- 447 Caulobacter vib...
WP_028853321 421 APSQWLSLLSEVA---VaiaAANSVarpvgtdgi-----------------eagevakrIAASLAS--GERKAVFLGna- 477 Ralstonia solan...
WP_010888138 428 RPARKPEKLAVIG---R---ESSIW----------------------------------RHAGIQA--ASNGHNAVArll 465 Deinococcus rad...

P57257       503 ----SHSFSDSIIKASINIAKAIKFRApd--hHVGVTLLTSSVNSLGAELLGGM-----------------S-------- 551 Buchnera aphidi...
Q9XAR0       504 asvaGGLTSAVRTSAATGARLVWIPRRag--eRGAIEAGALPSLLPGGRPATDP-----------------Rareevaal 564 Streptomyces co...
AAH06660     480 --alQRDDGAAILAAVSNMVQKIRVTTgvaaeWKVMNILHRIASQVAALDLGYK-----------------Pgv------ 534 house mouse
Q9ZCF6       447 --vyGRDDGYAVLSLIHKVVDKYNMMRd---dWQGFNILHNHASIVGGLDIGFN-------------------------- 495 Rickettsia prow...
Q37373       453 ---sSLLKGSLIVP-LFNFTNVICd------nWNGLNIISNDSSYLSTKEFNLS-----------------Ssh------ 499 Acanthamoeba ca...
AAO28140     461 --aeNHPQAATLRAAARQFAETTG---------AALCRIPQGANSIGLTQHGVL-----------------Ptgrd---- 508 Xylella fastidi...
AAO26882     504 ----SHSYNLDLIKVSFNIAKSLKVIGk----nVGLILLSSNVNSIGVSLLEGI-----------------S-------- 550 Buchnera aphidi...
WP_010919812 448 --alARADGAAILKAAAGLAKSVKVVRe---gWNGWNVLHTAAARVAGLDMGFV-----------------Pae------ 499 Caulobacter vib...
WP_028853321 478 --avAHPQFSKLHALAQWVAQQTG---------ATLGFLTEAANTVGGYIAGAL-----------------Pqg------ 523 Ralstonia solan...
WP_010888138 466 rpdtDELRAALKLLEEAEKPVVILG-------ADVLGADVLGSGTDGLAAQVSElanrtgakvlavaaaanSt------- 531 Deinococcus rad...

P57257       552 -----------IESA--LDDlkkEKA-DAVIFMEYDLYR--SVSEYDCEYFFKNKDNIITLDHQYTQTFKKSMLSLPSTN 615 Buchnera aphidi...
Q9XAR0       565 wgladlphrygRDTG--EIVeaaARG-ELQALLVAGVEVadLPDPTRARAALDEAGFVVSLELRPSEVSERADVVLPVAA 641 Streptomyces co...
AAH06660     535 ----------eaIRK--NP------P-KMLFLLGADG------GCITRQDLP-KDCFIVYQGHHGDVGAPMADVILPGAA 588 house mouse
Q9ZCF6       496 -------------TT--IKF---EGI-KLAYLLGAD--------AIPFDK--LKSAFIIYQGHHGDVGAMSADVILPAAA 546 Rickettsia prow...
Q37373       500 ---------sqNSHL--LN------F-PINFVLNYD--------KAVLVDS---SAFQIYQGHHGDTNAINSNLIFPSTS 550 Acanthamoeba ca...
AAO28140     509 -------aaamLVEP--CQ---------AYVLYGIEPGLdfADTATARQVLHGAK-VVAFSHFACVSTRDVADVILPIGL 569 Xylella fastidi...
AAO26882     551 -----------IEKV--INKvllKQI-DKIIVLENDLYR--YLPESIVDTLFKSSSCTVVIDHLNTRTLKQADIAIPTCN 614 Buchnera aphidi...
WP_010919812 500 ---------ggLSTAemLKP---GAL-DVLFLLGAD--------ECETAA---SDAFKIYLGTHGDNGAHKADVILPGAA 555 Caulobacter vib...
WP_028853321 524 ---------ngLDAA--AML---AQPrRAYVILGAEPEFdsANPQQARAALAHADTVVMLSPFASRAAMEHADVLLPVAP 589 Ralstonia solan...
WP_010888138 532 ----------gLAAL--NLLprsGAA-GYAGLTDAPAAFlsRLDPVGQGLLSLPRGFTVVHDTHLTETAQQADVVLPAVT 598 Deinococcus rad...

P57257       616 FTESSGTVINFEGRAQRFFQVYDPNFydksnCLCDSWKWLHTI 658 Buchnera aphidicola str. APS (Acyrthosiphon pisum)
Q9XAR0       642 VAEKPGTFLNWEGRVRFFEAALKPDQmt-rrLAPTDARVLQML 683 Streptomyces coelicolor A3(2)
AAH06660     589 YTEKSATYVNTEGRAQQTKVAVTPPG-----LAREDWKIIRAL 626 house mouse
Q9ZCF6       547 YTEQSGIYVNLEGRPQIAQKAVSTVG-----GAKEDIEIIKEI 584 Rickettsia prowazekii str. Madrid E
Q37373       551 FIEKNSFYSNSLAIVQKTKKILFSPG-----NSRDDWKILNAL 588 Acanthamoeba castellanii
AAO28140     570 LPEIDGTLTNLDGRTQAAKPGGKLPL-----EAREGWRVLRAL 607 Xylella fastidiosa Temecula1
AAO26882     615 SFESSGTVVNYEGRAQRFFKTYHPNSsenkkSILESWKWLHLL 657 Buchnera aphidicola str. Bp (Baizongia pistaciae)
WP_010919812 556 YTEKNGLYVNMEGRVQMGRRAVFPKG-----EAKEDWSILRAL 593 Caulobacter vibrioides
WP_028853321 590 FTETSGTYINCEGLPQSFNGVVRSLG-----DSRPAWKVLRVL 627 Ralstonia solanacearum
WP_010888138 599 NYEKRGTTVNLEGRFLALEQAALSAG-----EGADLIRTLTAL 636 Deinococcus radiodurans
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