5HYG


Conserved Protein Domain Family
AurF

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pfam11583: AurF 
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P-aminobenzoate N-oxygenase AurF
This family is a metalloenzyme which is involved in the biosynthesis of antibiotic aureothin by catalysing the formation of p-nitrobenzoic acid from p-aminobenzoic acid. AurF is a non-heme di-iron monooxygenase which creates nitroarenes via the sequential oxidation of aminoarenes.
Statistics
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PSSM-Id: 431946
Aligned: 65 rows
Threshold Bit Score: 181.639
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5HYG_A               11 AENAVINRLVGNWHRRAAvkrEEP--------DvyalfDPGRPDFREDMIPFRGHPIWERLSDETRSRLLSWGWVAYNRN 82  Streptom...
WP_023536944         10 YERDLLVQLTLRWGKRVAvkkDELdld---ghF-----DAALPDFPEHLVPVLALPGAGRLDRDARERILSASWIAYNAK 81  Streptom...
AMEG_HIPS:KALB_4450  22 AESAVISRLAGNWRRRATvkrDEP--------DldelfDLSRSDYPEGIIPFRDHDSWRGLPDHTRSRLLSWSWIAYNRH 93 
EGD22011             31 VESAIISSLAGSWPRRAVvkrPEP--------ElddlfDAEKADYPESLIPFRDHDVFTRLDEPVRRRILAWAWIAYNKN 102
WP_024101058         25 AESAVIAGLTRSWPRRAAvkkPEVdld---alF-----EADRADYPEQMLPFAEHPRYLALDEQQQARLRAWAWIAYNKS 96  Rhodococcus
WP_014747878         24 EVKALLQRIGDGWIKRAKvrrDAVdl----------afDPARPDFLEELLPFHAHPLYQRLAPELKSKILSAGWIIYNEK 93  Tistrell...
tigr:TERTU_3310      22 QSFEVLEQLAEHWELRAGvkkKELnpe--------itfDAHAPDFLPELLPFHNHDLFLSADSQAKSKALSCGWVAYNEK 93 
WP_012205541         11 AVRDALKKLSLLWKSRAAvnqDLPd-------YcglafDPARQDFTASLLPFRDHQAWVEAPQHLRDQCLSYAWGIYNLK 83  Delftia
WP_013139909         17 AYCERLATLSEGSVRRSF---NPFtdidwdspEfavtpNDPRWIL-PHADPIARTDWYQSLSEEQQIEVGMWRQATVAKT 92  Segnilip...
CCF65167             18 EYARMLHELADASVERHF---SPYddvdwdaaDlqirlDDPRWIL-PEFDPLGAHPWYQALPKDRQIAIGLYRQANTARV 93 
5HYG_A               83 TVLIEQRIAnpafELVIGGAYPGLGGQQLELAVAQAMVDEQYHTLMHINGSAVTRrmrrsdfsdrvlPDSHITTIHQEHL 162 Streptom...
WP_023536944         82 TAAIEDEIIlpacRLMLQDRIPVRRDDVAVDALHQTIIDEHYHILMCHNAVGVTRrrrdla-dvrfaPGVWSVVRGRDAV 160 Streptom...
AMEG_HIPS:KALB_4450  94 TVLAEQRVAnpafALVMEGEFPGLGGQDMEIALAQAMVDEQYHTLMHINASAVTRrkrqaelpdawlPESHTARTHRRLR 173
EGD22011            103 VMDVEQYVVnpgfRLLSQDAFGTGLGDTLTVATMQAMVDEQYHTLMHLNASALTRrrrgwdlperrlPYGPTVRRHQQAV 182
WP_024101058         97 VVDIEQHVVnpgfALITEDAFGIGPSDTVVTGVLQAMVDEQYHTLMHQQANVLTRrrrgwalkesvlPPCPTVREHRAAV 176 Rhodococcus
WP_014747878         94 TVAIESAIVspscYDALDGRIPGLTDETSRQIVCETLVDEAYHLLLVANANRLTRaqrgl--edlkiPGFNLVTMMNREK 171 Tistrell...
tigr:TERTU_3310      94 TIDIESYIVspscLDILYGRLPQTQNSIIKWTASETLTDEAYHVLLVTNTCRITRqrrgl--etlklPTFDLVRFMQREM 171
WP_012205541         84 TIYIECNVVtpacEDIIKTPPPSANRALLQDVMSQALLDEALHTRMSIMACNYIYemrgl--apldyADFNLVGWRNGVL 161 Delftia
WP_013139909         93 GLQFEVALI----QGMVRYAVSLPNGSPEYRYCTHEVAEECNHNQMFQEMVNRIGvp---------vTGMGRFHQFLTSY 159 Segnilip...
CCF65167             94 GLQFEQLLI----AGFMVYLNRLPNGSAEFRYATHEVIEECNHTLMFQEAVNRSGvd---------aPGFGPLFTAFSPL 160
5HYG_A              163 DRCEEPWQRSLTTLGFATVAEISINAYLDLLADDQE-IQVVNSTTVKLHNRDEYCHASISGEMMKQVYEALPADRRRFLL 241 Streptom...
WP_023536944        161 RAGLSGFDRDIVDIAFSLAAETTISGFLSTLATAQE-IQPMNRITTDLHRRDESGHAVVFRELCGSLYRNLDGVQQRMFR 239 Streptom...
AMEG_HIPS:KALB_4450 174 DGYPERWQRSLTTLAFATVSEISINAYLDLLAEDQD-IQVINSTTAKLHNRDEYCHASISDELGKIVYEVLDPDRKRFFV 252
EGD22011            183 DAAETPRESALVSLAFTTVAETSISSYLGLMTDDED-LQPVNRATVVLHRRDEYCHSSIAGELLKIVFERLDGNDRQLLL 261
WP_024101058        177 AHAETPRDAALVQLAFTTVAETSISAYLALLTTDPE-LQPVNRATVAVHRRDELCHASLAGELLTAVLTELDDTDRVRLL 255 Rhodococcus
WP_014747878        172 AVQSEDWQKILVHLATSVVSEIFVSDYLHQLSDCTE-IQPMNMATVAAHRHDELAHSKIFTLMTKTFYPALSPREQAFFA 250 Tistrell...
tigr:TERTU_3310     172 AMVDEEWKKRLINLATATVSEVFVSDYLSLIADAEH-IQPINRLTTDVHRKDEMAHSSIFKHLMKVIYPYLTQKEQDYLA 250
WP_012205541        162 AQCGAEWERRLARFAIACASETLITDYLKTMAEDRS-IQPICHEVTRTHAVDEWSHSSVFSSVATDIVQGLSNRERSYLR 240 Delftia
WP_013139909        160 GAQVLAELSPSAFFASVLAGEEPIDYVQKAILREGKaLHPIMEHVMAIHIAEEARHISFAHEFLKLRTPRASRLKRFALS 239 Segnilip...
CCF65167            161 VALFPRIS-APFFFMCVLAGEEPIDHIQKEYLRSDAgYHPMLASVMRIHVAEEARHISFAHEFLRRRVPKCSPAQRFLLS 239
5HYG_A              242 EKVVAGLEAFVAPDFTTWESIVAfeGVPGWEKAAAEVr-EAQGGTHLVQDH-SGIHTLLTEMD 302 Streptomyces venezuelae A...
WP_023536944        240 EALVTGLTAFRSADLDPWVAVAAqgGFEIDTGQLSEW---AASRPAPARDT-GPLQLLLDDLG 298 Streptomyces niveus
AMEG_HIPS:KALB_4450 253 DMLVAGLEAFVATDYTTWERILEieNVPDWQRMVQETr-EDTSRARLVRDY-TGLHSLMTEMD 313
EGD22011            262 AGLADGLEAFRSNDFSTWSAVLDheRVRGAHRIVADAa-HDSGRRNLVQDC-TAIRRLCDDLG 322
WP_024101058        256 DALGTAVAAFTGSDTSTWAAIIAreNIPGGDELVADTi-AVTEGRPVVQDC-SAIRRLCAGLG 316 Rhodococcus
WP_014747878        251 SVLPKPIEWFADLELDIWSSVLEqlRVPGAATIVADCr-PLNAAARERLDY-TGIVGLSHEVG 311 Tistrella mobilis
tigr:TERTU_3310     251 EILPKPVSWFASQELDVWESMLSqiRFPNYQEMIADC--RSEHIVNLGRIDySGLTTLADELG 311
WP_012205541        241 SIILKTVQMFANNELGAWSTVFTmvGMPHARDILHDV--GDSNEIGVYTDS---VQSLIDRIG 298 Delftia
WP_013139909        240 LAYPLIMRYVEELIVVPPKSFWD--RFDIPKSVKKEIfwQSEESRDFRRRLlADSRALAHEMG 300 Segniliparus rotundus
CCF65167            240 LAFPIALRVACDLIVIPPAAFWR--EFDVPRSVRRDLfwGLPSSKARLSGYfGDVRMLAEEIG 300
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