7KY9


Conserved Protein Domain Family
PhoLip_ATPase_C

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pfam16212: PhoLip_ATPase_C 
Phospholipid-translocating P-type ATPase C-terminal
PhoLip_ATPase_C is found at the C-terminus of a number of phospholipid-translocating ATPases. It is found in higher eukaryotes.
Statistics
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PSSM-Id: 465071
Aligned: 560 rows
Threshold Bit Score: 104.511
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7KY9_A       1199 VMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTsVPVI 1278 Saccharomyces...
XP_002139554 1828 AAISDVSITKFYQVFPLLSRAGRLTWYRTNLILFFSLFKTIYLMTPHVAYQFYCQWSGTPIYSVPLINAYFLVLTvVPPV 1907
A0E950        481 VNAGDISVNTLSEIKVLLLQKCKLHSERVSAMIIYLFYCAGFLGMTLFFFNWFCQFTATSLHDSMTVFLYIFLYTtPNAL 560  Paramecium te...
A0E8U0       1004 VNAGDISVNTLKEIKVLLLQKCKLHSERVSSMIIYLFYCAGFLGMTLFFFNWFCQFTATSLHDSMTVFLFIFLYTtPNAL 1083 Paramecium te...
XP_004031933  313 VNAGDIQISNLGQIKDLILIQGMSVFFRTQNVVYFLFYQALLFGMPLFYFNWYSSFLGTSFFESIWVFFYNFILNtTTLV 392 
XP_004027327  904 SNGGDIQLSQIKDIKDLILLEGVNNFFQTQNLIYFLFYKSLLFGLSLFYFNWYSSFLGTSMFESMWVFLYDFIFNaGTVI 983 
XP_001032308 1133 LPYADGQFTSFKQLNYLILSYGRQHYHKSQQLCTYMIEKSIIFTTLELIYAFHVMYSGQLFFCNLIYFFYEFLFAnWGAA 1212
Q22WA0       1215 INYSDFIIEDIKDLELLVLSYGRQHFNKTAIIAKQIIERNFTYVFIEILYRFYAGFATQSFFCYKYYLLLEIFFSfGNSI 1294 Tetrahymena t...
EAX87931      765 GIISDLTVDRFDQLSDIIFVTCQWLYDRITTMINFTIPRDTFLGLVQMAYQFQVAFSGTPLFTAAHILSVL-VFTgCPAV 843 
A0EF56        785 ETAFDIKMPTFSFLPKILIIHGRLNNIRQGSAISLINYLSFILFFIQFVYACYNRFSQNYLLNEFII-FIMMFFTiCYIF 863  Paramecium te...
7KY9_A       1279 LLAVLDQDVSDT-VSMLVPQLYR-VGI--LRK-EWNQ-TKFLWY--MLDGVYQSVI----CFFF---------PYLa-YH 1336 Saccharomyces...
XP_002139554 1908 VYGCTGVDVSPE--LLDLPILYN-VSR---NGyYISWvNYIQ-S--FLEGLFLGIV----SFYL---------GLIvtYS 1965
A0E950        561 VIGLADKQ-SQPiVNARFPAFYI-DGQirT--------RRFW-FfyLIEGFLESFIcaayTFYS--------------CT 615  Paramecium te...
A0E8U0       1084 VIGLADLE-TNPlVNTTIPTLYV-DGQirT--------KRFG-FyyLIEAFLESFIsaafTFYS--------------CT 1138 Paramecium te...
XP_004031933  393 TYGVFDNPFNNT-VLKFFPSLYV-AGQleKDK-ILT---SFL-LksVLEGILQGTI----IYYV---------SIYivSR 452 
XP_004027327  984 LYGLYDTPFQKI-VLQIFPSLYV-SGLveKQR-VLS---NFV-LqsVLEGLFQGTL----IYYV---------SIYivSR 1043
XP_001032308 1213 FFYLLDFDIQMY-QQIEYPQVYL-QGSlqKLT---SIpKYFYR---AFLSLCQGIF----IFFI---------TSYt-LQ 1270
Q22WA0       1295 YL-MFNFDLSIS-DQYRYPICYL-QSQfdENTsFKSIlKSFL------RSFYQALA----IIFI--------------IT 1347 Tetrahymena t...
EAX87931      844 SRSVLNKRVGEY-ILKNTPQKYYlRRR---KQpRLSF-IRFMIS--SVLCILGAIF----SVWFkalvdrdvrKPYn--- 909 
A0EF56        864 IFFSMAQDFPFE-ILRSQP-AYHlMVRtpKNP-----------YkiLLTQFFQGGIhgtfIVIS---------VIYt-FY 920  Paramecium te...
7KY9_A       1337 KNMVVte-nGLGLDHRYFVGVFVTAIAVTSCNFYV-----FM-E-----QY---RWD---W------FCGLFICL-S-L- 1389 Saccharomyces...
XP_002139554 1966 SPFSSak-sTGLPTLSAALTLYSAFGPLLSFFMKV--------------NSipwPF-----------LFFLILTPsTfVi 2019
A0E950        616 YMVNYawtnDGHQSDIQMVATSIIYLLITVSSLKV---------------------LfrlFynkvniVVIAFLLTfGlL- 673  Paramecium te...
A0E8U0       1139 YMVNYawtnDGHQSDFQMVATSIIYVVITVSALKV---------------------LfrlIqhnvhiVIIISLLTfGlL- 1196 Paramecium te...
XP_004031933  453 SLSLEg---YVSDFGM--IQIVVLYSIIVVFNFKI-----AFwCqshkvQC---IW-----------ISQLIFIA---M- 504 
XP_004027327 1044 SLSIDg---YNSDFGI--MSLVIIYSVILVFNFKI-----ILtSeshkvRI---VW-----------AGQLIVLV---L- 1095
XP_001032308 1271 EAV-------DGTGVVMNHGFTQICALFTIFNLMK--------YkqivhST---NIS----------YHYWVMVI-DyIl 1321
Q22WA0       1348 EIMKEpidsSGKIYSHQLISLTAFITFYNYQKIKTvirsaQL--------------S----------LSIILLVV----- 1398 Tetrahymena t...
EAX87931      910 ----------------DTISLQQFRYSMSATFILS-----CV-AwtatqTD---TWT---L------YHNISLFG-SlI- 953 
A0EF56        921 GSNDQ----NGYVHGYQLQQFMTFTISLLVIAFKP-----IIdQykivkSQ---IY-----------LAMAYIFA-T-Vm 975  Paramecium te...
7KY9_A       1390 AVFYGWTg-----------IWTSSSSS-------NEFYk--gAARVFAQ-PAYWAV--LFVGVLFCl-lP-----RFTID 1440 Saccharomyces...
XP_002139554 2020 LLAFINThnlvq---wseiFFTG--------------------FEFLGS-TLFILTlpLLFMCIVI---F-----NTIWY 2067
A0E950        674 -VGFVFInyrrdfsnfdyqELTY----------------------------QLFTRfnSIVAMVFSl-iGcyfinYFLHN 723  Paramecium te...
A0E8U0       1197 -VGFVFLnyrgnfsdfdyqELTY----------------------------QLFTRfnSIVAIVFCl-fGcffinYFLHD 1246 Paramecium te...
XP_004031933  505 VVGYVYInqegyfaswnwvITSA---------------------QIFNReDTIFCL---VFNILCClvlS-----HFVNV 555 
XP_004027327 1096 IIVFIFAndtdnfsnwdwvMTTG---------------------EIFKRgDTICCL---IFNVIVSlivS-----HFVNV 1146
XP_001032308 1322 FIIVMFIiqtkg---isriSYNNld---------------kmVSAFFSStSSFFIF---LTIGFICl-iP-----EIIQL 1374
Q22WA0       1399 -DYFIYI----------------GFIYafcsqyiSDMLgtnsVGEMSNFgKSFLAIslSICVAIICs-iP-----DIAQA 1455 Tetrahymena t...
EAX87931      954 -CFFVGYs-----------LVTDNQGN-------SQTSg--vSSTM----SGNWISslSTFIFPICsi-----flQFSYT 1003
A0EF56        976 I------------------IYKNN------------EE----MADLFETgVKTKDLcaLVFYPICAl-sP-----NLIGQ 1015 Paramecium te...
7KY9_A       1441 CIRKIFY---PK 1449 Saccharomyces cerevisiae S288C
XP_002139554 2068 LLINAFY---PN 2076
A0E950        724 FIKLIYF---PN 732  Paramecium tetraurelia
A0E8U0       1247 FIKLNIF---PT 1255 Paramecium tetraurelia
XP_004031933  556 FLVEFLL---PN 564 
XP_004027327 1147 FMVEYLQ---PN 1155
XP_001032308 1375 VNERLIN---RN 1383
Q22WA0       1456 AY--------ET 1459 Tetrahymena thermophila SB210
EAX87931     1004 LFKRFFEqekQV 1015
A0EF56       1016 FIQRLLS---TN 1024 Paramecium tetraurelia
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