2LUY


Conserved Protein Domain Family
Stc1

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pfam12898: Stc1 
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Stc1 domain
The domain contains 8 conserved cysteines that may bind to zinc. In S. pombe this protein acts as a protein linker which links the chromatin modifying CLRC complex to RNAi by tethering it to the RITS complex. The region is reported as a LIM domain here, but has a slightly different arrangement of its CxxC pairs from the Pfam LIM domain pfam00412, hence why it is not part of that family. The tandem zinc-finger structure could mediate protein-protein interactions.
Statistics
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PSSM-Id: 432862
Aligned: 58 rows
Threshold Bit Score: 46.5006
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2LUY_A        13 CMRCRKVKGIDSYSKTQWSKTftfvRGRTvsv-----sdpKVICRTCQPKQH--------DSIWCT-ACQQTKGINEFSK 78  Schizosaccharom...
XP_003657978   7 CEHG-EWKTRDQFSKTQLEKY----EQQArngta-tpartGIRCKEHSAKQA--------LELKCNgPCGRWRELRFFSK 72 
XP_003667181   7 CEQG-EWKPRASFSKNQLSKY----DRNAqkgss-tpsktGIRCMEHSSKPV--------LEEKCRgPCGRWREKRLFSK 72 
Q2GNQ5         8 CQQG-EWKTRDQFSNRQLSKY----DRnekat----psktGIRCVEHSGGPV--------NELTCKgPCGLKRDRRFFSK 70  Chaetomium glob...
EPE06472      27 CFTNGEWKERSEFSTRQLDKFsrsga---------sagnsQISCREHTTQVR--------RELKCEgPCGDWYPLEVFSR 89 
ERS96357      21 CFAGGEWKPRSEFSNRQLEKFararv---------ppdqsEISCRAHSTQIR--------RELKCEgPCAKWQPIENFSR 83 
EGS22906      18 CVGGNHWVYLTELSHSQRQKYhnlkNAGRatp-----cnaQICCPEHVDMvdgngnirpkdgVECD-ICQRVLPPDAFSK 91 
EHA55550      13 CTNGSHWAPRGDFSKSQLQKW----HGSFgd--------tKISCSKHTNLAA--------AELRCTgPCGRVLAVTCFSK 72 
ESA43677      32 CMNGKEWQDRSAFNPKRLREY----ENMRrsnkavtaynsFISCKAHSGHDP--------RDQQCQgSCMRILPLEKFSK 99 
EGU78697      29 CASGNEWKPLDMFSKAQQRNT----RFLIdsgrkfdpgntGMICKEHNSTPA--------LEHGCV-GCDRTLPYDAFSL 95 
2LUY_A        79 AQRHV-LDPRCQICVH 93  Schizosaccharomyces pombe 972h-
XP_003657978  73 STRRNgKNRRCDPdcl 88 
XP_003667181  73 STVRK-GVYWCVDCVD 87 
Q2GNQ5        71 RTIQH-DTFWCVHCTE 85  Chaetomium globosum CBS 148.51
EPE06472      90 STRSH-SKTWCLHCTE 104
ERS96357      84 STRNH-SKTWCTDCTD 98 
EGS22906      92 STFRS-GQPICKGCrs 106
EHA55550      73 NQRSAgGSQECLDCVA 88 
ESA43677     100 NSRKL-RTFKCIDCTQ 114
EGU78697      96 NQRRL-EDWRCLQCVA 110
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