Conserved Protein Domain Family
REC114-like

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pfam15165: REC114-like 
Meiotic recombination protein REC114-like
REC114-like members are necessary for meiotic DNA double-strand break formation. It functions in conjunction with Mei4. This family of proteins is found in eukaryotes. Proteins in this family are typically between 43 and 259 amino acids in length.
Statistics
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PSSM-Id: 464541
Aligned: 7 rows
Threshold Bit Score: 313.71
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q7Z4M0        21 WPLQRYARCIPSNTRDPPGPCLEAGTAPCPTWKVFDSNEESGYLVLTIVISGHFFIFQGQTLLEGFSLIGSKDWLKIVRR 100 human
EHB11862      21 WPLQRYGRFMLSEARELSESGPKAGAVPSPTWKVFDSSEESGYLVLTIVISGHFFISQGQTLLEGFSLIGSKNWLKIVRR 100
NP_001100295  20 WPLRRYGRFMLLDNGESPGPSSAAAAAPSPTWKVFESSEESGCLVLTIVVSGHFFISQGQTLLEGFSLIGSKNWLKIVRR 99 
XP_002919747  21 WPLQRYGRFMPSGTGEPPRPGQDAGAASSPTWKVFDSNEESGNLVLTIVISGHFFISQGQTLLEGFSLIGSKNWLKIVRR 100
XP_007478185  15 WSLKHYGRFLPNSTDRFGVEAEAEAGSDSSSWKVFESNDKYGALVLTIVVSGHFFISQGQTLLEGFSLIDGKKWLKIVRQ 94 
1_pfamImport   1 WPLRRYGRFMPGGLGPASGSCLSTGNHAFAGWKVLESNEESGFLVLTIVISGHFFISKGKDVLEGFSLIDASQWLKIVRN 80 
XP_015199122  16 WPLRRYSRFLPKATAG----------DSTSSWKVFNSSESAGQLELTIVQSGHFLITQGHGLLEGFSLLNASNFLKVIQK 85  spotted gar
Q7Z4M0       101 VDCLLFGTTIK--DKSRLFRVQFSGESKEQALEHCCSCVQKLAQYITVQV-PDGNIQelqLIPGPPRATESQGKDSAKSv 177 human
EHB11862     101 MDCLLFGATIKarSRSRMFRIQFGGESKEQALEHCCSCVQSLARYTTVEV-PDSITR---LSPGLLWAGDHQGRDCAKSi 176
NP_001100295 100 MDCLLFGTTIK--DKSRMFRVQFSGESQEEALEHCCGCVQTLTQYVTVQE-PDRITQelqQSPGPREAGESQGKD----- 171
XP_002919747 101 MDCLLFGTTIK--DKSRMFRVQFGGGSKEQALEHCGSCVQKLAQYVTVQV-PDGVSQelgLSPGPLRAGESCAQH---V- 173
XP_007478185  95 VDSLLFGSILK--EKSRMFRVQFGGNSEEQALENCFACVQKLEQYITIYV-PDDLSQelqLGPSLLIGPEGQGKDGAETg 171
1_pfamImport  81 ADCMLFGSKAK--DKHRMFRVQFMGDSKSQAEGNCDDCVQKLADYVPVQV-IDSARQellQGHSLLLDDQNHQKNAILR- 156
XP_015199122  86 TDILLFRFKIK--SESRMFRVQFEGSSKEEALEQCQSAVIALQQYLFVEStPVQG------------------------- 138 spotted gar
Q7Z4M0       178 -PRQPGSHQHSEq----------QQVCVTAGTGAPDGRTSLTQLAQTLL--ASEELPHVYEQSAWGAEELGPFLRLCLMD 244 human
EHB11862     177 -PLQPGPCQDLE-----------RGKCVAAGVGAPEGRTSVAQLAQSIL--ASEELPLAYEQSAWSVEELGPFLRLCLMD 242
NP_001100295 172 -PLQQGSSLILE-----------QHVCMAAGTGLLEERTSVTHLAQSIL--APEKLTLAYEGSSWGAEELGPFLRLCLMD 237
XP_002919747 174 -PPQQGPPQNPEk----------PQPCGPASTSASGGRSSMSSLAQSLL--VSEARPPICEQPAWDAEELGPFLRLCLMD 240
XP_007478185 172 lRHQRGLHLN-------------VKQHHSSSYTFPDGRITMIQLAQSVL--TSAELPLAYEQAAWNAGELGPFLKLCLMD 236
1_pfamImport 157 -KKQNKKHQHSAq----------QRAYVLSQIGKIKGRLSVAELAQYMMs-TNTKLPLAYQHSTWNAEDLNSFIRLCLLD 224
XP_015199122 139 --------EASSadthsaerkisEGEGSGATSEINQGSIPIRLLAQSFLgeSKLTLPLAYRHPTLPTEQLGPFLQLCLLD 210 spotted gar
Q7Z4M0       245 QNFPAFVEEVEKELKKL 261 human
EHB11862     243 QNFPAFVEKVENELKKL 259
NP_001100295 238 QNFPAFVEEVEKELKKI 254
XP_002919747 241 QNFPAFVEDVEKELKKL 257
XP_007478185 237 QNFPAFVEDVEKELKKL 253
1_pfamImport 225 QSFPAFVEEVEKQLKKI 241
XP_015199122 211 QNFPAFVEQVERELKKL 227 spotted gar
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