Conserved Protein Domain Family
CAAD
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pfam14159: CAAD 
CAAD domains of cyanobacterial aminoacyl-tRNA synthetase
This domain is present in aminoacyl-tRNA synthetases (aaRSs), enzymes that couple tRNAs to their cognate amino acids. aaRSs from cyanobacteria containing the CAAD (for cyanobacterial aminoacyl-tRNA synthetases appended domain) protein domains are localized in the thylakoid membrane. The domain bears two putative transmembrane helices and is present in glutamyl-, isoleucyl-, leucyl-, and valyl-tRNA synthetases, the latter of which has probably recruited the domain more than once during evolution.
Links
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Statistics
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PSSM-Id: 433752
Aligned: 105 rows
Threshold Bit Score: 51.7531
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_001691500       63 KQVQGKWESTDDseK-PAAIAIIVGVIVAQIAIGATIDAVDKIPIVNKGLQLIGVAVTGLFTYRYFTDPAERESVKKSID 141 
jgi:MICPUN_53162   64 KTIADKWEDTEN--K-SAVITYVAGGAALVWLSGTVVGAINSIPILPKVMELVGLGYSTWFVYRYVLYKDSRKELVEQFD 140 
XP_006366639       93 SNVKDTWDRLEK--K-PTVFIYGGSAILGLWLSSIIADTLDSIPLLPKFLELVGLGYFGWFVYRYLLFKSGRDELGRDVQ 169 
ERM93863           28 SDLKEKWDAVEN--K-STVILYGGGALVALWLSTVVIGAVNSVPLLPKIMELVGLGYTGWFVYRYLLFKSSRKELASDIE 104 
Q0DXV3             22 EDLKAKWDAVEN--K-STVLTYAGGAIIALWLSSVIVGAVNSVPLLPKFMELVGLGYTGWFVYRYLLFKESRKELADDVD 98   Japanese ...
XP_004973492       70 SELRDKWDAIEN--K-SSLLLYGGGAVLAVWISLVVVRALDSVPLLPGLLELVGLSYSGWFVYRYLLFQENRKELADNLD 146 
Q6ZKB9             72 SELKEKWDAIEN--K-SSVLFYGGGAIIAVWLSSIVVKAVDSVPVLPNILELVGLGYSGWFVYRYLLFKENREELANGFD 148  Japanese ...
XP_009403349      111 SKLNDQVD--------STILFYGAVALVALWISSTIISVIDSIPVFPKVLEVVGLGYTVWFSSRYLIFKETRDDFFSKLD 182 
EFN53210           66 KDLQEKWDKVEN--K-TSVIVYGAGGIVVLWLASTVVGALNSIPLLPKAFELVGLGYSAWFTYRYLLFKSSREELVEDIE 142 
WP_015226504      765 NQINTFPKQLNQ--RlLTRVGIGIFGVFIFTLVFAFILTLEQFPLIPSFLKLVGVGYSGWFIYRYLLTQQKREAFGKLVR 842  Halothece...

XP_001691500      142 AFVKSVTG 149 
jgi:MICPUN_53162  141 ALKNKVSG 148 
XP_006366639      170 ALKKKITG 177 
ERM93863          105 ALKKKIAG 112 
Q0DXV3             99 SLKKRIAG 106  Japanese rice
XP_004973492      147 DLKKRITG 154 
Q6ZKB9            149 ALKKRITG 156  Japanese rice
XP_009403349      183 DLKEKILG 190 
EFN53210          143 SLKKKISG 150 
WP_015226504      843 ETKEELLG 850  Halothece sp. PCC 7418
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