Conserved Protein Domain Family
PRK13983

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PRK13983: PRK13983 
M20 family metallo-hydrolase
Statistics
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PSSM-Id: 237578
Aligned: 53 rows
Threshold Bit Score: 563.703
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
150401264   1 MNLMDETVEISSELIKINSVNPEFGGVGEEKKSKFVLDKLNEYIKKyniknySIKQYNIKDDKDII--RPNIVAKFDFGK 78 
159040705  16 GELREFIINLYKDFIPIRALAPENGGDGEWDRAQYLINVARQYFDD-------VKVIEAPDPRVSRgsRPNVVATIKGID 88 
48478172    1 -MDESFIIETAKRLIPLKSVGPLSDGPGESRKAEEICKIIKELGYN-------YERYDIDG-------RPNIIVRIGSME 65 
13541910    1 MEDRDFIIEVARRIIRIPSISPASGGEGESKRADEIGRILSELGYT------DFKRYDTKDDTGTV--RSNIVLKIGNNS 72 
16082569    1 MPDRDFIVEVARRIIRIPAISPASGGEGEKDRADEIEKILRELGYN------DYQRYDMKDEYGKI--RSNIVIRAGKGE 72 
256810646   1 -MLIEEAIKLEKDLIKINSVNPSFGGKGEKEKAEYVKRKLIEYVDKyniknyTLKEYNTIDKYGIE--RPNIVFKIDFKK 77 
261403836   1 MDLTKEAIQLESDLIRINSVNPSFGGKGEKEKANYVKRKLIEYVNKygitnyTLKDYTTIDKYGIE--RPNIVFKLDFGK 78 
289193192   1 -MLREEAINLESDLIKINSVNPSFGGKGEKEKAEYVKSKLMEYVEKykiknySLKEYNVIDKCGIE--RPNIVFRIDFGK 77 
296108779   1 ----MDVIELASDLIKIRSVNPYFGGEGEKEKGEYVKRKLIEIVKKhnfkdyELKEYNTIDKFGIL--RPNIVFKADFGR 74 
297619589  37 KELETETINIASNLIRINSVNPGFGGKGEFEEAQYILKKLNEYVEKynv-dlKIKEYNTTDNDNII--RPNIVVDLDLNK 113
150401264  79 EE-TLHIISHLDIVPEGDLNLWSNPPYKPVIKDGKIYGRGSEDNHKGIVSSLLLMNMIFQnSNfnnkklFNPKYNLSLIF 157
159040705  89 ESrTFWVIAHMDTVPEGDRALWSVEPYQATVKGDLVYGRGVEDNGQGIVMGLAVGKVLRD-LG------IKPPFNYGLIL 161
48478172   66 K--TLWIISHMDTVPEGDINLWHYDPYQATVSGDLIYGRGTEDNGQGIFTSLLLLKNLKP---------DRLKFNLGLAF 134
13541910   73 K--TLWLIAHIDTVPVGDPSLWTKPPFELTVEGDKMYGRGTEDDGQAVFTALLILRDLKK---------IRMNYNFGIAF 141
16082569   73 K--VLWLVAHIDTVPVGDPALWTKPPFDVTVEGDRMYGRGTEDDGQAVFTALLILRDIKK-NG------LKQKMQFGVAF 143
256810646  78 DR-TLHIISHLDTVPEGDISLWETNPYEPVVKDGKIYGRGTEDNHKGIVSSLLLLKMIFE-NN------IEPKYNLSLIF 149
261403836  79 EK-TLHIISHLDTVPEGDISLWETDPYKPVLKDGKIYGRGSEDNHKGIVSSLLLLKMIFEsDN------VKPKYNLSLIF 151
289193192  78 DK-TLHIISHLDTVPEGDISLWETNPYEPVVKDGKIYGRGAEDNHKGIVSSLLLLKMIFE-NN------IEPKYNLSLIF 149
296108779  75 EK-TLHIIAHLDTVPEGDLSLWETNPYEPVIKDGKIYGRGAEDNHKAIVSSLLLLDKLLE--D------KESKYNLSLIY 145
297619589 114 EN-SLTIISHMDIVPEGDIALWDTEPYEPVIKNGKIYGRGSEDNGKGIVSSFLILKLLLDeLKqksitaDDLKYNLKLIF 192
150401264 158 VSDEECGSKYGIQHIL-KRKQEIFKKNDLFIVPDFGAPDGNLIEIAEKNILWIKFKIKGKQCHGSTPNNGVNADVLAFNF 236
159040705 162 ASDEEVGSKYGIRYIL-DTERDLFKASDLILVPDAGNPDGSMIEIAEKAILWLRITITGKQGHASVPESALNAHRLGMML 240
48478172  135 VSDEETGSNFGIKYLI-KN--NIFKKDDLIIVPDAGTPDGRTIEIAEKSILWLKINSHGRQYHASMPGEAINATKELYKF 211
13541910  142 VADEEVGSKYGIQYLL-TK--DVFGKDDLIIVPDAGSEDGLNIEISEKSILWLKFRVIGKQYHASMPPNAINSFRESAKF 218
16082569  144 VADEEMGSKYGIQYLL-EK--DIFRKSDLIIVPDAGSEDGMTIEIAEKSILWIRFSVKGKQWHASMPVNAINAFREGSKF 220
256810646 150 VSDEEDGSEYGLKYLL-NFEDEIFKKDDLIIVPDFGTPTGEYIEIGEKGILWIKFNIKGRQCHGSTPENGLNANIVAFNF 228
261403836 152 VSDEEDGSEYGLKYLL-NFENEIFKKDDLIIVPDFGTPKGDFIEIGEKGILWIKFDIEGKQCHGSTPENGVNADVIAFNF 230
289193192 150 VSDEEDGSEYGLKYLLdNFEDEIFKKDDLIIVPDFGTPTGEFIEIGEKGILWIKFNIKGKQCHGSTPENGLNADIVAFNF 229
296108779 146 VSDEEAGSKYGLKYLL-NFEKEIFDKNDLIIVPDFSSEDGSYIEIGEKGILWIKFIFEGKQCHGSVPEEGFNSNVVAFDF 224
297619589 193 VADEENGSTYGIRHLL-KYEDEIFKKGDVIIVPDFGVGHGNLVEIAEKQIMWIKFTITGFQCHGSTPHKGINAGMLSFLF 271
150401264 237 ANNLYNYLYSKYNKKDELFNPAYSTFEPTILSNNIENTNTIPGLVELNFDCRILPDYDINKVLKDIDNFIDNFINKIPey 316
159040705 241 ALKLDEVLHSTYNAEDPLFTPPESTFEPTRVDKNVDNVNTIPGRHVFYFDCRVLPRYSLDDVLATVNKTAEEFCREKG-- 318
48478172  212 VLNLESRLKEKYNKINDVFDPPYSTFEITKHGKNVDNINTIPGFDSQFLDCRILPDYDVNDVLRFIDDEIAGFKSP---- 287
13541910  219 ILKLDKTLHAKYSAIDKLYNVPYSTFEPTKHEKNVDNINTIPGTDVFYYDCRVLPQYSLDDVISTVEAEISDFQKESN-- 296
16082569  221 MIDLDRRLHEKFTVKDDLYNVPYSTFEPTKHEKNVDNVNTIPGTDTFYFDCRVLPQYSLDDVLKTVDEAISDFQAHSQ-- 298
256810646 229 VNELYNNLYERFNEINPIFLPEYSTFEPTILKNKVENPNTIPGYVEVVFDCRVLPTYTIDEILKFIDDFIKNFDFKKYik 308
261403836 231 ANGLYKQLYEKFDNVDEIFLPKYSTFEPTILKSGVENPNTIPGHVEVVFDCRILPTYSLEDVLKEIDNFIKTFDFRGGlk 310
289193192 230 AYELYNSLYEKFDEVNPIFLPEYSTFEPTILKNKVENPNTIPGHVEVVFDCRILPTYKIKDVLKFIDEFIRNFDFKKYik 309
296108779 225 SNKLYKELYSKFNKVNNIFLPEYSTFEPTIVKNKVTNPNTIPGKTEVVFDCRILPDYSIEEIISEIDNFIKGYNFKPIhs 304
297619589 272 GDMLYKTLYNTYNAKDDIFTFPYSSFEPTIVKNSVENANTIPGNVEMYFDCRVLPDYNVDDVLKTIDNTIMKFKRELPin 351
150401264 317 lifydkeelknITIDYEILN-KEQSQKTPKNSKLVLELKNAIKKVLNKEPILCGMGGGTVGAFLRAEGYNTVVW-GIGEE 394
159040705 319 -----------CGFSVEVLNrDDPAPPTSPNSEVVQRLTRAIKMIRNIDVKYMGIGGGTYAKYIRMLGIPVAVW-MTSSN 386
48478172  288 -----------ARISYEIIQrEDAPEPTKKDSEIVNLLSDAIE-----NPKVVGIGGGTCAAFFRENGIPAVVWsTTDVD 351
13541910  297 -----------AKIEYSVMQkEQSPPKTPEDSEVVKKLVSSIRKLRKKEPNVLGIGGGTCAAFFRQLGLPAVVWyTTIEE 365
16082569  299 -----------ARISYDLVQkEQAPKKTPEDSEVVVRLMESIKKKRGKTPKAIGIGGGTCAAFFRRLDIPAVVWfTTIEE 367
256810646 309 hyn----rsvkVEITYDILK-SENPNYSSENSEVVKELKKAIKKVLNREAKLCGMGGGTVAAFLRCKGYDVAVW-GIGEE 382
261403836 311 yyd----psveMQINYKILK-EEQPNYTKKDSKVVLELKRAIKKVLNEDAKLCGMGGGTVAAFLRFKGYEVAVW-GIGEE 384
289193192 310 hyd----slieAEITYEILK-AENPNYTDEDAEIIKELKKAIKKVLNRDAKLCGMGGGTVAAFLRYKGYSVAVW-GIGEE 383
296108779 305 s--------geGRVRREILK-LEKPNFTKEDSLVVRELKRAIKEVLNVEPKVCGMGGGTVAAFLRERGYDVAVW-GIGEG 374
297619589 352 lkyycedlsdnIEITYNVEN-LEKSGKLSENSKSVVEICDSIDKILNIEPELCGMGGGTVAAPIRVKGYEAVVW-GMGNE 429
150401264 395 TAHQPNEHIKLNDLIKMAKIYYEIME 420
159040705 387 TAHSPDERVNLNDVINDVKVTLASMM 412
48478172  352 VAHQADEFVRISNIIKDAKTIERIIY 377
13541910  366 NAHKPDEFCLISHILMDRDVIEDMLS 391
16082569  368 NAHRPDEFCLISHILMDRDVLEDVLV 393
256810646 383 TAHQPNEHIKVEDLVKMAEVFYEILK 408
261403836 385 TAHQPNEHIRIDDLVKMAKVFYEIIT 410
289193192 384 TAHQPNEHIEIEDLVKMAEVFYEILR 409
296108779 375 TAHQPNEHIKIGSLEKMAEVFYKMLR 400
297619589 430 TAHQPNENVDIVDLLNMGKIYLTMMI 455
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