2EBZ,4WBO,4YHJ,3NYO,4WNK,1FQK,2D9J,1CMZ,2OWI,2OJ4,2BV1


Conserved Protein Domain Family
RGS

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pfam00615: RGS 
Regulator of G protein signaling domain
RGS family members are GTPase-activating proteins for heterotrimeric G-protein alpha-subunits.
Statistics
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PSSM-Id: 459870
Aligned: 54 rows
Threshold Bit Score: 78.4255
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2EBZ_A    18 SFERLLQDPV-GVRYFSDFLRKEFSE--ENILFWQACEYFNHVpahDKKELSYRAREIFSKFLCSKATTPV-NIDSQAQ- 92  human
Q5NUF5    57 AFDSVCVEQPiGKRLFREFLEANQEYh-GACRLWKDIEDYDLA---EDSERAKKASKIVQRYMDPSAKHFCpFLPEDIIa 132 Japanese medaka
Q49HN0    57 SFDSMCVRQPiGKRLFQQYLESEADYk-NPVDLWKDIEDYIVA---QENDRAKKAQKIVNKYYESSSKNFCdFLGDKAVs 132 zebrafish
CAJ83092  52 DYTSLCEKQPiGRRLFRQFCDTREHFl-RCINFLDAVADYEVS---PDEKRKETGDEIISRFFNPESSDYMpEIPDAYMe 127
4YHJ_A    52 DYSSLCDKQPiGRRLFRQFCDT-KPTlkRHIEFLDAVAEYEVA---DDEDRSDCGLSILDRFFNDKLAAPLpEIPPDVVt 127 human
P70507    51 DFSSLCDQQPiGRLLFRQFCNT-KPDlkRCIEFLDAAAEYEVT---IEEEQREFGLSIYSRFFKENSEVSLpQIPPDLVk 126 Norway rat
3NYO_B    52 DYHSLCERQPiGRLLFREFCAT-RPElsRCVAFLDGVAEYEVT---PDDKRKACGRQLTQNFLSHTGPDLIpEVPRQLVt 127 human
4WNK_A    52 DYCSLCDKQPvGRLLFRQFCET-RPGleSYIQFLDSVAEYEVT---PDEKLGEKGKEIMTKYLTPKSPVFItQVGRDLVs 127 cattle
Q9Z2G7    53 HFHSLCEQQPiGRRLFRDFLAT-VPKysQAVAFLEDVQNWELA---EEGPAKTSTLQQLAATCARDPGPQs-FLSQDLAt 127 thirteen-lined grou...
Q49HM9    52 DFESLCEKQPiGKKLFRQYLSQGGPEctTAAEFLDDLNEWELS---ESAARDKARTNIINKFCKEGSKSSLtFLTGDVAt 128 zebrafish
2EBZ_A    93 LADDVLRA--PHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQEC 134 human
Q5NUF5   133 KVKENLEV--VGDDLFAAALAKTLDYLREAPYVFFLESMYLKRF 174 Japanese medaka
Q49HN0   133 RVKEDFKN--IRGDLFKESEQQLLVHLEAKALTGFKDSMYFLRY 174 zebrafish
CAJ83092 128 ECSENLGKn-PSKEIFTKCISQLHEFLSGSPFREFQDSMYFDRF 170
4YHJ_A   128 ECRLGLKEenPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQF 171 human
P70507   127 ECKCNLKQssPSQNVFQDCAGVIYKYLSEKPFEEYQESTYYNRF 170 Norway rat
3NYO_B   128 NCTQRLEQg-PCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRF 170 human
4WNK_A   128 QTEEKLLQk-PCKELFSACVQSVHDYLRGEPFHEYLDSMYFDRF 170 cattle
Q9Z2G7   128 KCRAASTDe-ERKTLVEQAKAETMSFLQEQPFQDFLASPFYDRF 170 thirteen-lined ground squirrel
Q49HM9   129 KCKAVSDK--DFEEVMGQVKTATKEFLKGKPFTEYQASPFFDKF 170 zebrafish
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