4E8B,1NXZ,1VHK


Conserved Protein Domain Family
TIGR00046

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TIGR00046: TIGR00046 
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RNA methyltransferase, RsmE family
Members of this protein family, previously called conserved hypothetical protein TIGR00046, include the YggJ protein of E. coli, which has now been shown to methylate U1498 in 16S rRNA. [Protein synthesis, tRNA and rRNA base modification]
Statistics
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PSSM-Id: 272873
Aligned: 11 rows
Threshold Bit Score: 241.914
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4E8B_A         2 RIPRIYHPEPLTSH-ShIALCEDAANHIGRVLRMGPGQALQLFDG-SNQVFDAEITSASKKSVEVKVLEGQIDDRESPLH 79  Escherichia col...
P44627         2 RIPRIYHPISLENQ-TqCYLSEDAANHVARVLRMTEGEQLELFDG-SNHIYPAKIIESNKKSVKVEILGRELADKESHLK 79  Haemophilus inf...
P72667        65 AYRLVVAPEQIIEA-T-VTLTTAQLHYLQRVLRLQKGDGFMVLDG-GGGVWRAQLNDLAHG--TAQLLETVSEQNELPLP 139 Synechocystis s...
O25138         1 -MRFVYHPLAKEPV-L--KIEGESYTHLYRSRRVKSASRLDLRNLkDGFLYTYEHAEITKKHALLKLVGARLLEVMASKK 76  Helicobacter py...
O51333         1 MKQIVLDENCLAGN-FiIVKDAKIYHHLVNVRRLKKGDKLNILLK-DKELRASEIVKIGSNFIKFTTNKIDKIE-KNNFE 77  Borrelia burgdo...
O51089         1 -MNLMLITFNEFKT-G-ISLNDTRAEHLVKILKLKDNDKFKFGILgEKNIYHCIYKKDKKLFFKKIFKVGESNK---LKK 74  Borrelia burgdo...
O66552         1 -MHVFYSEERRGNL-L--ILREGEVKHFR-VRRIEKDEEFGVIH--EGKIYVCKVRREDKREISCEIVEELETKLPPKDI 73  Aquifex aeolicu...
WP_000533579  11 RIPRIYHPEPLTSH-ShIALCEDAANHIGRVLRMGPGQALQLFDG-SNQVFDAEITSASKKSVEVKVLEGQIDDRESPLH 88  Enterobacteriaceae
P54461         3 RYFIELTKQQIEEA-PtFSITGEEVHHIVNVMRMNEGDQIICCSQ-DGFEAKCELQSVSKDKVSCLVIEWTNENRELPIK 80  Bacillus subtil...
1NXZ_A         1 RIPRIYHPISLENQ-TqCYLSEDAANHVARVLRXTEGEQLELFDG-SNHIYPAKIIESNKKSVKVEILGRELADKESHLK 78  Haemophilus inf...
1VHK_A         5 RYFIELTKQQIEEApT-FSITGEEVHHIVNVXRXNEGDQIICCSQ-DGFEAKCELQSVSKDKVSCLVIEWTNENRELPIK 82  Bacillus subtilis
4E8B_A        80 IHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGV-KLDSErLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLE- 157 Escherichia col...
P44627        80 IHLGQVISRGERMEFTIQKSVELGVNVITPLWSERCGV-KLDAErMDKKIQQWQKIAIAACEQCGRNIVPEIRPLMKLQ- 157 Haemophilus inf...
P72667       140 VTLAIALPKGSGFEEIIRPCTELGATAFQPLLTERTLL-KPSQ----NKLERWQRIVTEAAEQSERQWLPPVAAPLTFGq 214 Synechocystis s...
O25138        77 THLILSVIEIKNIEKILPFLNQLGVSKLSLFYADFSQR-NEKID--IAKLERFQKILIHSCEQCGRSALMELEVFSNTK- 152 Helicobacter py...
O51333        78 ISIFISSLKGRKIDLVLRQVVEIGVSEINIINADRSVS-KIDINnASAKILRFSKIIDEALKQSGNKIVPKINFYNNFF- 155 Borrelia burgdo...
O51089        75 LYVLIGMIRPIVAKRIIKELASIGTYKIIFFNTELTEK-SYLNS-KIFKNNDCEKHLIAGAMQGKITYLPKIKIIKNLK- 151 Borrelia burgdo...
O66552        74 TLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQ-KEEA--ILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLS- 149 Aquifex aeolicu...
WP_000533579  89 IHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGV-KLDSErLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLE- 166 Enterobacteriaceae
P54461        81 VYIASGLPKGDKLEWIIQKGTELGAHAFIPFQAARSVV-KLDDKkAKKKRERWTKIAKEAAEQSYRNEVPRVMDVHSFQq 159 Bacillus subtil...
1NXZ_A        79 IHLGQVISRGERXEFTIQKSVELGVNVITPLWSERCGV-KLDAErXDKKIQQWQKIAIAACEQCGRNIVPEIRPLXKLQ- 156 Haemophilus inf...
1VHK_A        83 VYIASGLPKGDKLEWIIQKGTELGAHAFIPFQAARSVVkLDDKK-AKKKRERWTKIAKEAAEQSYRNEVPRVXDVHSFQq 161 Bacillus subtilis
4E8B_A       158 --------AWCAEQDE-GLKLNLHPRASNSINTLPl--P-VERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTE 225 Escherichia col...
P44627       158 --------DWCAENDG-ALKLNLHPRAHYSIKTLPt-iP-AGGVRLLIGSEGGLSAQEIAQTEQQGFTEILLGKRVLRTE 226 Haemophilus inf...
P72667       215 f------vEKVAGPETlALLCVTRLNSPMLGAYLKqsnL-PAQIVLATGPEGGWTDNEISLAIAKGFQPVSLGKRILRAV 287 Synechocystis s...
O25138       153 --------E-ALKAYPkASVLDFKGETLPASADFE--------KGVIIGPEGGFSEPERGYFKEREIYRIPLD-MVLKSE 214 Helicobacter py...
O51333       156 ---------YLPYSFCtTRYYVAHPSGMILSKNESf--DnFGKIGIIIGPEGCFSESEIVFFKEKGFNFVRFNTPILRAD 224 Borrelia burgdo...
O51089       152 --------ESLKYIQQeNFEIKILLEKNSEKNLIDi--EqINNAVIIVGPERGFTEKEKQLIAQYNFSPYSISTNTLRTE 221 Borrelia burgdo...
O66552       150 --------DLIPESEEnIILDNFYEGVKPKDVNLE-----AKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTE 216 Aquifex aeolicu...
WP_000533579 167 --------AWCAEQDE-GLKLNLHPRASNSINTLPl--P-VERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTE 234 Enterobacteriaceae
P54461       160 llqrmqdfDKCVVAYEeSSKQGEISAFSAIVSSLP---K-GSSLLIVFGPEGGLTEAEVERLTEQDGVTCGLGPRILRTE 235 Bacillus subtil...
1NXZ_A       157 --------DWCAENDG-ALKLNLHPRAHYSIKTLPt-iP-AGGVRLLIGSEGGLSAQEIAQTEQQGFTEILLGKRVLRTE 225 Haemophilus inf...
1VHK_A       162 llqrxqdfDKCVVAYEeSSKQGEISAFSAIVSSLP---K-GSSLLIVFGPEGGLTEAEVERLTEQDGVTCGLGPRILRTE 237 Bacillus subtilis
4E8B_A       226 TTALTAITALQVRFGDL 242 Escherichia coli K-12
P44627       227 TASLAAISALQICFGDL 243 Haemophilus influenzae Rd KW20
P72667       288 TAPTVALAQINALLES- 303 Synechocystis sp. PCC 6803 substr. Kazusa
O25138       215 SACVFVASIAQV----- 226 Helicobacter pylori 26695
O51333       225 TAIIYSLAYFKALLEDY 241 Borrelia burgdorferi B31
O51089       222 TATIAASIITASKLINM 238 Borrelia burgdorferi B31
O66552       217 TAVVSIVSILMNF---- 229 Aquifex aeolicus VF5
WP_000533579 235 TTALTAITALQVRFGDL 251 Enterobacteriaceae
P54461       236 TAPLYALSAISYQTELL 252 Bacillus subtilis subsp. subtilis str. 168
1NXZ_A       226 TASLAAISALQICFGDL 242 Haemophilus influenzae
1VHK_A       238 TAPLYALSAISYQTELL 254 Bacillus subtilis
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