7CR0,7BYL


Conserved Protein Domain Family
KCNQ_channel

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pfam03520: KCNQ_channel 
KCNQ voltage-gated potassium channel
This family matches to the C-terminal tail of KCNQ type potassium channels.
Statistics
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PSSM-Id: 460954
Aligned: 14 rows
Threshold Bit Score: 332.494
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7CR0_A       404 SPSADQSLED-SPSKVPKSWSFGDRSR-ARQAFRIKgaaSRQNSEe--aSLPGEDIVDD-KSCPCEFVTEDLTPGLKVSI 478 
Q9JK97       465 SPSSEQVGEAsSPSKVQKSWSFNDRTR-FRASLRLK---PRCSAE----EGPSEEVAEE-KSYQCELTVDDVMPAVKTVI 535  house mouse
XP_015203979 482 SPSSESVPEAtSPGRVQKSWSFNDRTR-FRTSLRLK---PRPSADv---EAPAEDGAED-KAPHCDVTMEEVIPAVKTLI 553 
XP_016851815 408 SPSTENINEAaSPTKVQKSWSFNDRTR-FRASLRLK---PRIPVEa---DGPVEESSEE-KAYQCDLTFEDIMPAVKTLI 479 
EDM16164      53 TPLNVDAIEE-SPSKEPKPVGLNNKER-FRTAFRMKayaFWQSSEd---aGTGDPMTED-RGYGNDFLIEDMIPTLKAAI 126 
XP_003462849 466 SPSADQSLED-SPSKVPKSWSFGDRSR-ARQAFRIKgaaSRQNSEe--aSLPGEDVVEDnKSCNCEFVTEDLTPGLKVSI 541 
7BYL_A       748 SPSSEQVGEAtSPTKVQKSWSFNDRTR-FRASLRLK---PRTSAEd----aPSEEVAEE-KSYQCELTVDDIMPAVKTVI 818 
XP_022530323 422 SPGAEINTEGsSPAKVQKSWSFNDRTR-FRPSLRLKs-qSRSTTDaesnVGAGEEGFDD-KGCHCEISAEDLLPAVKTVI 498  Mexican tetra
XP_029690384 448 SPGAEEGVEA-SPYKVAKSWSFTDKNRgTKNSFKARgstSRQNSEe--aSLPGEEMGDD-KSCHCEFLTQELPSSLKVTI 523  torafugu
XP_019205488 430 PGGADDGAEA-SPSKVTKSSSFTDKNRgAKNAFKARgsiSRKNSEe--aSLPGEEIGDD-KSCHCEFLTQELPPGLKVAI 505  Nile tilapia
7CR0_A       479 RAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPaiTDKD-R-TKGPA--------- 547 
Q9JK97       536 RSVRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQARVDQIVGRGP--GDRKtR-EKGDKgp------- 605  house mouse
XP_015203979 554 RAVRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGAiqPDRKvRsEKGEKtp------- 626 
XP_016851815 480 RAVRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQIVGRGAiaIDKKvR-EKGEKss------- 551 
EDM16164     127 RAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPpsTPKHkKsQKGSAftypsqqsp 206 
XP_003462849 542 RAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPaiTDKDr--TKGPA--------- 610 
7BYL_A       819 RSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGP--GDRKaR-EKGDKgp------- 888 
XP_022530323 499 RAVRIMKFHVAKKKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQvpVDKKlR-EKLMS--------- 568  Mexican tetra
XP_029690384 524 RAICIMKFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLCRIKNLQTRIDMIVGPPPpsTPRHkKsTEGPRvdqivg--- 600  torafugu
XP_019205488 506 RAICIMSFLVSKRRFKESLRPYDVMDVIEQYSAGHLDMLSRIKNLQTRIDMIVGPPPptTPRHkKsTEVPRvdqivg--- 582  Nile tilapia
7CR0_A       548 ---------EAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIP 589 
Q9JK97       606 --------sDTEAVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSG 648  house mouse
XP_015203979 627 --------pELDPLDELSMMGRVVKVEKQVQSIEHKLDLLLNFYTQCLKKG 669 
XP_016851815 552 --------lEMELVDELSMLGRVVKVEKQVQSIEHKLDLLLGVYSQCLRKG 594 
EDM16164     207 rnepyvaraATSETEDQSMMGKFVKVERQVHDMGKKLDFLVDMHMQHMERL 257 
XP_003462849 611 ---------EAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIP 652 
7BYL_A       889 --------sDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSG 931 
XP_022530323 569 ---------EGDLLEDVSMLGRVCKVERQVQSIESKLDSLLDIYRQVLRKG 610  Mexican tetra
XP_029690384 601 ----kspkaDGDPGDDLSMMGRLVKVEKQVLCMDRKLDFLVNVYVQRMGIT 647  torafugu
XP_019205488 583 ----kgpkgEGDAVEDQSMMGRLVKVEKQVVCMDRKLDFLVNVYVQRMGIP 629  Nile tilapia
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