2PBE


Conserved Protein Domain Family
Adenyl_transf

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pfam04439: Adenyl_transf 
Streptomycin adenylyltransferase
Also known as Aminoglycoside 6- adenylyltransferase (EC:2.7.7.-), this protein confers resistance to aminoglycoside antibiotics.
Statistics
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PSSM-Id: 461311
Aligned: 50 rows
Threshold Bit Score: 247.081
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2PBE_A            4 RSEQEXXDIFLDFALNDERIRLVTLEGSRTNRNIPPDNFQDYDISYFVTDVESFKENDQWLEIFGKRIX--------XQ- 74  Bacillus sub...
Q830C7            2 RTEEEMFQLIMDVAKQEEHIRAVGMVGSRTNVKAPKDSFQDFDIVYIVEPCAEFFETATWIAKFGQPLI--------MQ- 72  Enterococcus...
BAK93575          2 RSTTEMTDLILETAQKLPEVKAVAMSGSRANKSIPKDNFQDFDITYIVDDIDPFIKNRQWLDKLGKRLI--------MQ- 72 
WP_015509579      2 REEAELHQLILSVGQRV-GARAIGLSGSRTDPQAPKDFLQDFDVVYVMDDIQPLVDDPSWLEAFGPIMI--------RQ- 71  Enterococcus...
EQC80490          2 RNEAEMLAVILRVGQKI-GVQAIAISGSRREPNAISDRFQDYDIVYIVDNMQELIAEPSWLEEFGQIMI--------MQ- 71 
adrc:B739_0034    2 KVREEKLRTIIEWSEKNEDVRVLLLTSSLVNPLALVDEFSDLDIEFVFEDNTNYISDKSWTLKFGNPIA--------MI- 72 
WP_006341522      8 K--------IVEWAKQEQTVKAVILQGSHATNQA--DRYSDYDLSLFCTEIETFTYNDTWLSAFGNVWIcvheklclAQq 77  Parachlamydi...
WP_004235664      2 ESIEQIINNIISFALLDPRIDAVIITGSVARQNQA-DRFSDINAELIGSSHDELFQDSRWLSRFGVPLI--------IR- 71  Morganella m...
jgi:Clocel_2181   2 RNTQEMMDLILNIAKEDARIRAVYLSGSRVDPDATQDKYSDFDIVYIVNEIQSFTKDDHWLDQFGDRLI--------MQ- 72 
WP_013281084      2 KTYDEMYDLIIKTATEDDRIRAATMEGSAVTPGAVRDGFSDFDITFFVSDIREFTADKNYMRKFGDILI--------MQ- 72  Butyrivibrio...
2PBE_A           75 -KPEDXELFPPELG--NWFSY-----IILFEDGNKLDLTLIPIREAEDYfaNNDGL-------VKVLLDKDSFINYKVTP 139 Bacillus sub...
Q830C7           73 -RPKEMTLFPTEPK--TRETF-----LMLFEDGQRIDLTLCPLAEKDNWh-EGDSL-------AIILLDKDENLPPLPVA 136 Enterococcus...
BAK93575         73 -TPDEMGLRANKAE--EKFTF-----LMLFEDGNRIDLTLCSTSGIHPWl-ANEPV-------LKVLSDPYHLLTDVPDV 136
WP_015509579     72 -TPEASTIYPPSLG--GCFTY-----LMHFLDGVRIDLMLCPLALVDRLa-NEPGL--------QPLLDPDQILSFVNQA 134 Enterococcus...
EQC80490         72 -TPESSVLSQPSLG--GRFTF-----LMHFEDGNRIDLMLCPVELIHLL--QAEPF-------LERLYDPKELLQGMTVP 134
adrc:B739_0034   73 -EEDE-----------SCFNHkhamkMLLYEDGVKVDFKLYSKSKFIKEt-QEKELpedwdigYKILIDKDGITKQMLKP 139
WP_006341522     78 iVPTR---------------------LVIFEDGIKVDFTLFSPDILRTVhcLPP---------FKILVDKENMLK---NV 124 Parachlamydi...
WP_004235664     72 ------KAASREDDslCWPSC-----QVLYEKGRKVDFVLAGRERIIQM--AAHGLdsiyqrgYAVLLDKTGLTAGLPEY 138 Morganella m...
jgi:Clocel_2181  73 -KSVDWYSHQYDYNsnEDFIY-----LMQFLDGNRIDLTLVDIENVKRRi-NDKEP-------RIILLDKDGIDGLHNIE 138
WP_013281084     73 -TPDDWYMEPYDYNgkKRFAY-----LTQYKDGNRIDLTFIDVSEIGKQt-DFNEP-------RTILINKDGFTELKEIT 138 Butyrivibrio...
2PBE_A          140 NDRQYWIKRPTAREFDDCCNEFWXVSTYVVKGLARNEILFAIDHLNEIVRPN-LLRXXAWHIASQKGYSFSXGKNYKFXK 218 Bacillus sub...
Q830C7          137 SDKNYTVTVPDQQQFNDCCNEFWWVSTYVVKGLCRNELFYAVTHLYEYCQQE-LLRLLSWQAAWQEPEPISVGKQFKYLK 215 Enterococcus...
BAK93575        137 SEKVYQIFPATQTAFAECCNEFWWVSTYVVKGLVRGELLYASDHLYTICQKE-LLRLLSWEAVLQKG-PLNPGKNYKYLF 214
WP_015509579    135 NHSHYWIKRPTQAAFQEHCNEFWWVSTYVVKGLLRKQLIYAADHLYTICWQE-LLWIEDLFVAQAQQFQVSTGKNHKYLQ 213 Enterococcus...
EQC80490        135 NASIFWIKPPTEKTFHDSCNEFWWVATYVVKGLVRNQLFYAADHLYQICWQE-LLRQYDWYLAHQADYRLSTGKNHKYLQ 213
adrc:B739_0034  140 TYQISIIKKPSEKEFQNLINDFWWDTTYVAKCLVRDEIFYAKFMSETVIRTEyLIPLIEWHIASEHNWNITTNKYGRLFK 219
WP_006341522    125 ENEAYERDNPSLQQFVRCIKEFWFEAYHVAIALKREDLWNAKFRFEAI--DAfLLQMIEWHASALNEGQ-QILHGGKWMR 201 Parachlamydi...
WP_004235664    139 ADPAAVLTPPDQQTFLENWQNFWLEASQVPVYYLRNEL-WTARLRDVAMKQW-LITLLEWHVLLRSDGTQDVWYAGRHLG 216 Morganella m...
jgi:Clocel_2181 139 VKDYYYIQKPSKEEFRDCCNEFWWLNTNIAKGLCREELMYVKFFMEHYQMDM-FLKMLNWKIGIEYDFSVSTGKCYKYFK 217
WP_013281084    139 SGDIFFIQKPSEFEFYNTVNEFRWVSNYATKGLCRHQFYYAKYSMEHLMMNM-FMKMINWKVGIDNDFKVTTGSFSKYLR 217 Butyrivibrio...
2PBE_A          219 RYLSNKEWEELXSTYSVNGYQEXWKSLFTCYALFRKYSKAVSEGLAYKYP-DYDEGITKYTEGI 281 Bacillus subtilis
Q830C7          216 NYVTPDTMDQLASLLDFSSKEACWNSLIKTQAFFDVVAQDFAKMAQFTYHlQEAKKVTEYTNSL 279 Enterococcus faecalis
BAK93575        215 NFLPLKQ-APFEKLLNFSSINLCWQSLLATQDFFHSEAQNFAQAAGFDYMnTVAENIMDYTQEH 277
WP_015509579    214 SFLTEKEWRELTSLLDFSTITACGQSLLKMQKRFDGQAKNISEKLGLAYDwQEAENVQTYTKYw 277 Enterococcus casseliflavus
EQC80490        214 SYLSEEEYERLTA-LCFSSVETCGESLWKIVQLFDEIARYVSRQHQFLYHeEEASKVMKYVQKW 276
adrc:B739_0034  220 KYLNQEMWAKTEQTFSGSDIKENWTALFSMTDLVSEIGTELSKKLEYKYPdKLENDIRKYLAGL 283
WP_006341522    202 SWVTPCCWEYIQKISSLPSVS--WERLDETMQLFRLLATETAFKWHYLDAlDLDFNISHYISSL 263 Parachlamydia acanthamoebae
WP_004235664    217 TWLPPGLYGRFMATLDNRDRVRAARAHMAMLTLYRDVALRVIETQKFDIDiTLADKIIAlvtdr 280 Morganella morganii
jgi:Clocel_2181 218 RYLSDSDMDRFTNLFPNGEYKEIWDKLLKICEFFHELAITVSTHFNFEYSkEEAENVIEYLKRM 281
WP_013281084    218 KYLTEDEMKRFEGIFAGGAYEDMWDKVFLMYDYFEDLSIYVADKLGFSLDlEESSNVREFMKKR 281 Butyrivibrio proteoclasticus
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