224004504   1 LIGSIDQGTSSSRFLIV----TSTGCM---LSTAQVEFDQCYPDrsphntdtsdgssscAGWHEHDPFAIWDSVVTCIVR 73 
145344681   8 CVGALDQGTTSTRFVVYettaPRDARTyvkIASAQREHAQRYPA---------------PGWCEHDAEEIFERALTCARE 72 
159468069  11 CIAALDQGTQSTRVYIF----DKECNV---LASHQAELPQIYPQ---------------AGWCEHDPLEIWRTVLQCISQ 68 
168022832  12 YVAAIDQGTTSTRFIVY----DTAAKV---VVSHQLEFTQIYPQ---------------AGWVEHDPMEILDTVRKAMEG 69 
225463623   7 FVGSIDQGTTSTRFIIY----DRSAQP---VGSHQVEFTQFYPE---------------AGWVEHDPMEILESVRVCIEK 64 
255073615   5 LVGAIDQGTTSTRFILYrvvgDGVLQP---LASHQMEHKQIYPK---------------PGWCEHDPEEIYANTLTCIAS 66 
297839893   7 FIGSIDQGTTSTRFIIY----DHHARA---VASHQVEFTQFYPE---------------AGWVEHDPMEILESVKVCIAK 64 
302808481   7 FVAAIDQGTTSTRFILY----DQDAKP---VASHQLEFEQIYPQ---------------AGWVEHDPLEILKSVKVCMEE 64 
302806254   7 FVAAIDQGTTSTRFILY----DQDAKP---VASHQLEFEQIYPQ---------------AGWVEHDPLEILKSVKVCMEE 64 
302839392   6 CTAALDQGTQSTRVFIF----DRDCAP---IASHQADLPQIYPQ---------------AGWCEHDPMEIWRTVLECLSR 63 

224004504  74 TVEELAQRGLDItsgdvSSWIKAVGITNQRETTVAWNDRTGRVYYNAIVWDCSRTNEQAEAIMHEAASSNGGtdanakpi 153
145344681  73 ALRSAGVTASDL---------ACVGITNQRETTCAWRRSDGTALANAVVWLDSRTRETCDAVVREACDGDKNa------- 136
159468069  69 AWEQHVVSSGRP-----PLRMLSLGIPTQRETTVVWSRSTGQPLHNAIVWLDNRTSELCEHLSRVFGGVDA--------- 134
168022832  70 ALAKGKEKGLDI-----LDNLKAIGITNQRETTVIWSRSTGKPYYNAVVWMDSRTSSICRHLEKQHPEGGRR-------- 136
225463623  65 AIDKATADGHNV-----DSGLKAIGLTNQRETTLIWSKSTGLPLYHAIVWMDARTSSICRKLEKELPGGRTH-------- 131
255073615  67 ALEAVPGGATAS-------DVACVGITNQRETTVAWSKRTGKPLHNAVVWLDMRTSDLCESLTSEVMGGDKDa------- 132
297839893  65 ALDKATADGHNV-----DGGLKAIGLTDQRETTVVWSKSTGLPLHKAIVWMDARTSSICRRLEKELSGGRSH-------- 131
302808481  65 TLNKAASKGLSF-------AVKAIGITNQRETSIIWSKSTGKPLYNAIVWMDGRTSSICKRLEENLSGGSKH-------- 129
302806254  65 TLNKAPSKGLSV-------AVKAIGITNQRETSIIWSKSTGKPLYNAIVWMDGRTSSICKRLEENLSGGSKH-------- 129
302839392  64 AWE--------------------------RETTVVWSRTTGRPLHNAIVWLDNRTSELCDKLAA-VHGGRDA-------- 108

224004504 154 daLRAKTGLPIASYFAGTKVRWLIDKIPQLQQDItsptERNHVRFGTIDTWLLYMLTGYQrsiaemennerlayEG--GE 231
145344681 137 --FVATCGLPVSTYFSAMKMRWLLENDEGVREAA----REKDLCFGTIESWLVYKLTGGK-------------------A 191
159468069 135 --FRSVTGLPISPYFSATKYLWMLENIPQVAAAV----ESGDAAVGTIDSWLIWQLTGGA--------------DG--GV 192
168022832 137 --FVSTCGLPIHPYFSATKILWLMEHVPEVKAGV----ESGDALFGTIDTWLIWNLTGGL--------------NAeePV 196
225463623 132 --FVETCGLPISTYFSALKLLWLLENVDAVKKAV----EAGDALFGTIDTWLIWNMTGGL--------------NG--GV 189
255073615 133 --FREVCGLPISTYFSGVKMRWLLDNCDAVKAAA----AENDLAFGTIDSWLLHRLTGSA------------------GT 188
297839893 132 --FVESCGLPISTYFSAMKLLWLMENVDDVKDAI----KKGDAIFGTIDTWLIWNMTGGV--------------DG--GL 189
302808481 130 --FVESCGLPISTYFSALKLLWLLETVPEVKSAV----LAGDALFGTVDSWLIWNMTGGI--------------SG--GL 187
302806254 130 --FVESCGLPISTYFSALKLLWLLETVPEVKSAV----LAGDALFGTVDSWLIWNMTGGI--------------SG--GL 187
302839392 109 --FRAVTGLPISPYFSATKYLWMYENVPEVRAAV----DSGDAAVGTIDSWLIWQLTGGA--------------AG--GV 166

224004504 232 FKTDVSNASRWLFMNLDTVDWDESLVKAFPVKs--------aLPKIVPSIDCTIGTAHGIPCSdgkmalkNVAIASILGD 303
145344681 192 HITDVSNASRTLLMRLDDLTWDAATCETLGVPmd-------aLPEIKSCAEDFGEIDASIEGLg------GIKITGCIGD 258
159468069 193 HVTDVTNASRMLLMDLDALDWHEPTLAAFRCPra-------vLPRIVSNSEVYGTISASGPTC-------GVPIAGSLGD 258
168022832 197 HVTDCTNAARTMLMDLTTLQWHEPTLKDLGIPrs-------iLPKIISNVELIGKVSEDWPFA-------GIQLAGCLGD 262
225463623 190 HVTDVSNASRTMLMNLKTLDWDKPTLDTLGISae-------iLPKIVSNAEIIGTVAKGWPIS-------GLPISGCLGD 255
255073615 189 HVTDATNASRTMLMDLRTQTWHEPTAVKLGVPmh-------sLPRIVSCAEEYGVITEGALK--------GVKLTGCLGD 253
297839893 190 HVTDVTNASRTMLMNLKTLNWDQDTLKTLGIPae-------iLPKIVSNSEVIGEICKGWPIP-------GIKIAGCLGD 255
302808481 188 HVTDCSNAARTMLMNLKTLSWDKGILESLGISidllphvynmLPRIISNSEVIGKVCEGWPLA-------GVPLAGCLGD 260
302806254 188 HVTDCSNAARTMLMNLKTLSWDKGILESLGISidllphvynmLPGIISNSEVIGKVCEGWPLA-------GVPLAGCLGD 260
302839392 167 HVTDVTNASRTLLMDLDSLEWHESTLEAFRCPrv-------vLPRIASNAEVYGLITPTHATApqlygsgGVPIAGCLGD 239

224004504 304 QQAALFGQTCfHPGEAKCTFGTGLFLMMNTGDTSIPSTQGLLTTVAYQLGK-RSNGDesrskpiFALEGSVAFSGSTLQW 382
145344681 259 QQSATLGQRC-DVGQAKNTYGTGCFMILNTGSTIVRSKHGLLTTMAWQLGGrDKTPK-------YALEGSVAIAGAVVHW 330
159468069 259 QMAAVLGQRC-RPGEAKNTYGTGCFMLLNTGQRRIASNHGLLTTVAFKLGP-DKPAN-------YALEGSVAVAGLGVSW 329
168022832 263 QHAATLGQQC-KAGEAKSTYGTGCFIVLNTGEQIVPSNHGLLTTISYKLGP-DAPTN-------YALEGSIAIGGAAVQW 333
225463623 256 QHAAMLGQAC-RKGEAKSTYGTGAFILLNTGEEVIESKHGLLTTLAFKLGR-EAPTN-------YALEGSIAIAGAAVQW 326
255073615 254 QHAATLGQRC-DAGRAKNTYGTGCFMLLNTGGNVVESKHGLLTTMAWRLGK-DATPA-------YALEGSVAIAGAGVQW 324
297839893 256 QHAAMLGQAC-RKGEAKSTYGTGAFILLNTGEVPIKSGHGLLTTLAYKLGP-QAHTN-------YALEGSIAIAGAAVQW 326
302808481 261 QHAAMLGQHC-KKGEAKSTYGTGCFILLNTGEEVVPSTHGLLTTVAYKLGP-KAPTC-------YALEGSIAIAGAAVQW 331
302806254 261 QHAAMLGQHC-KKGEAKSTYGTGCFILLNTGEEVVPSTHGLLTTVAYKLGP-KAPTC-------YALEGSIAIAGAAVQW 331
302839392 240 QMAAMLGQRC-RPGEAKNTYGTGCFMLLNTGQRRIASTHGLLTTVAFKLGP-DKPTN-------YALEGSVAVAGLGISW 310

224004504 383 LRDKLNIISSASEAEALATSVSSSENMYLVPAFSGLFAPHWRPDARGCMVGLTASHSKAHVVRSALESSAYQAREVFDAM 462
145344681 331 LRDNLGLIKTASDIESLAGTVEDAAGVSFVPAFSGLFAPRWREDARGVIVGLTQYVNKGHIARAALDAIAFQSRDVLDAM 410
159468069 330 LRDNLGLIGSAAESEVLAASVRDSGGVYLVPALSGLLAPRWRADARGVLVGLTSFTTRAHVVRAMLEAICFQTREVLDAM 409
168022832 334 LRDNLGIIKSSSEIESLAKTVNNTGGVYFVPAFSGLFAPWWRDDARGVLVGITRYTNKAHIARATLESMCYQVKEVLTSM 413
225463623 327 LRDSLGIISTASEIEELAAKVDSSGGVYFVPAFNGLFAPWWRDDARGVCIGITRFTNKSHIARAVLESMCFQVKDVLDSM 406
255073615 325 LRDNLGLIRSAADVEPLAASVPDAGGVYFVPAFSGLFAPRWRPDARGVCVGLTQFTTKAHLARALLEAICFQTVDVLEAM 404
297839893 327 LRDSLGIIKSASEIEDLAAMVDSTGGVYFVPAFNGLFAPWWREDARGVCIGITRFTNKSHIARAVLESMCFQVKDVLDSM 406
302808481 332 LRDNLGIIKSASEIEALASTVENTGGVYFVPAFSGLYAPRWRDDARGVCVGITRFTHKGHLARSVLESMCFQAKEVLDSM 411
302806254 332 LRDNLGIIKSASEIEALASTVENTGGVYFVPAFSGLYAPRWRDDARGVCVGITRFTHKGHLARSVLESMCFQAKEVLDSM 411
302839392 311 LRDNLGVIGSAAESEVLAASVPDTGGVYFVPAFSGLLAPHWRADARGVLLGMTSFTTRAHVVRAMLEAICFQTREVLDAM 390

224004504 463 VRD--------SNVQLKEMRVDGGATANRFLMQFQADILNAPVVRPEYLETTGWGAAVAAGLAMGVWVDLEEVG------ 528
145344681 411 RQDma----esTSHSLSALKVDGGASANNLLMQIQADCIGLNVIRPSDVETTARGAAYAAAIGAGLMTEEDVFAnvs--- 483
159468069 410 RRDael---deHHGGLAALRVDGGAAANDVLMQMQADLLQVPVLRPAFRETTSMGAALAAGLAVGFWTKEEVFS------ 480
168022832 414 KADagn--ieaTVGGEFLLRVDGGATVNNLLMQLQADLLGSPVVRPVDIETTALGAAYAAGLAVGVWTKEQIIEq----- 486
225463623 407 HKDagekgevkNEKGEFLLRVDGGATINNLLMQIQADLLGNPVVRPADIETTALGAAYAAGLAVGIWTEDEIFDs----- 481
255073615 405 RKDa-------SDLDMTALHVDGGATANGLMMQTQADLLGLRVFRPANVETTAMGAALAAGVGAGLFSERAVFEdtpade 477
297839893 407 NKDagekgsldNEKGEFLLRVDGGATANNLLMQIQADLMGSPVVRPVDIETTALGAAYAAGLAVGFWKEADIFEs----- 481
302808481 412 LKDak-----vEHKEKFVLRVDGGATVNNLLMQIQADLLGTDVVRPKDIETTALGAAYAAGLAVGLWKEEQIFT------ 480
302806254 412 LKDak-----vEHKEKFVLRVDGGATVNNLLMQIQADLLGTDVVRPKDIETTALGAAYAAGLAVGLWKEEQIFT------ 480
302839392 391 RRDael---deHHGGLAALRVDGGAAANDLLMQLQADLLQVPVVRPAFRETTSLGAALAAGLAVNMWSKEEATA------ 461

224004504 529 ---------RMWKVNTKWQPSMSVEKRAECWKGWNKAVQRSLNWLDEGR 568
145344681 484 -------egDGDRDITEFVPKLSIEARETNYARWNDAVERTLNLSA--- 522
159468069     -------------------------------------------------    
168022832 487 --------gAVQEAPTVFHSQITDDERNKRCLSWNKAVERSFGLAELDF 527
225463623 482 --------gEKVKLATTFYPALDEERRNKKVESWCKAVSRTFDLADLSL 522
255073615 478 siadaewlrDEMANRAYFEPAIGEDERARRYAGWCDAVERSLNLAPQQG 526
297839893 482 --------gEKAKNSKVFRPAMEEETRKKKVASWCKAVERTFDLADLSI 522
302808481 481 ---------ADEEVGQTFTPSIAEPEREKRYTSWCKAVERSYALADLA- 519
302806254 481 ---------ADEEVGQTFTPSIAEPEREKRYTSWCKAVERSYALADLA- 519
302839392 462 -----------------FQPGVTPAAAGRRYDRWRKAVERALDLADLAP 493