Conserved Protein Domain Family
Trep_Strep

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pfam09605: Trep_Strep 
Hypothetical bacterial integral membrane protein (Trep_Strep)
This family consists of strongly hydrophobic proteins about 190 amino acids in length with a strongly basic motif near the C-terminus. It is found in rather few species, but in paralogous families of 12 members in the oral pathogenic spirochaete Treponema denticola and 2 in Streptococcus pneumoniae R6.
Statistics
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PSSM-Id: 430711
Aligned: 97 rows
Threshold Bit Score: 86.7877
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Elen_3089   37 KEVVTAVLFSALMIVVMFVVGSvTMLGVDFSMLFMAATYVLVVAPLYMLMVMRVNRFGV-TAFYACVMALVYLMFGN--- 112
jcvi:FSU_2178   17 RDLVNVGIFGALYLVLSGLGAS-IGFI-PAFIVVSTCVVSLVTSVPLFLFFSKVERPLLcCVLLCTLFGVVMTISGH--- 91 
WP_012858701     9 KDLVTIGVFTVIYFIVMFTVGM-IGIS-PFLFLIYPAILGMATGTIVMLFMAKVQKPWG-LFILGIISPFIMFVMGH--- 82  Streptobacill...
WP_009608046    24 RDLINIGIFTAIYFVIQFVFML-CGGIHPALWVFMPALDGLFAGIPFMLMCAKVQKPGA-VVIMGLIVALIYFATGMf-- 99  Eggerthella
CDD29051        13 KDVITVGIFSAIYFVINFAFML-LGGLHPLLWILMPGFIALFTGIPYLMMCAKVQKVGS-VLLMGLITGLIYYVTGQf-- 88 
CDF41533        13 KDLISIGIFSAIYFVLNFICML-LSGLHPVIWILMPALIALVTGIPFLLMCAKVQKFGA-VLLMGMVTGLLYFVTGQf-- 88 
CCY59675        13 KDLISIGIFSAIYFVLNFVCML-VSGLHPIIWILMPALIAVVTGIPVLLMCARVQKFGA-ILLMGMVTGLLYFVTGQf-- 88 
WP_015564603     8 KDLGLTIVFSVIYFAVVLAATI-MGGIHPLLYLFVTALIALVAWIPYMYVMAKVPKAGV-VLIMNLFVAIAFVAFGE--- 82  Eubacteriales
jgi:Shel_28280   4 sSIVRVLVASLVYLAVYPLASS-SGLIHPACYAYAGTVTPLLFAFVYLYASANMQCFGA-AAIPNGVLLVIGLVTGEggl 81 
WP_012799882    11 RVLLCAVLYAALSAVVCFTGAV-----HPIFFVGYQITAGILLSGIAIWAFRNVQAPGV-AACLALAMILLLVAIGDa-v 83  Slackia helio...
jgi:Elen_3089  113 LWYMLPFYLV-GGLAIDALFLRTaAqRAKPNRIVAAWATFsALYSLSSIIPILV-NLQGYLQELAEVrMMGE-EYVNAYL 189
jcvi:FSU_2178   92 GISFGLLCVI-YGVLAGLCLKLF---HKNFVGCLLA-NVMiSFVPSSMMIPLWF-STEEYLAYCS---SVCDsAYIAHLA 162
WP_012858701    83 TYVIAVHALI-VMFIAEIIRRVG-N-YKSFKYNMLAFAVF-NTWICGSLMQMLL-AREKYIELSM---MMGK-EYVDHLE 153 Streptobacill...
WP_009608046   100 TPLILAMMAA-SCVVAEVIRAVA-R-YRSFLGNAVAYAVF-GLGMCGSPLPLWV-FHDSFVSQIAEQ-GMGA-DYLASLD 172 Eggerthella
CDD29051        89 TIVILVTFVL-ACGLAELTRGIT-H-YHSMAGNLVSFVLF-SVGMVGSPLPIWL-MREDFLRQITEQ-GMPA-DYVNTLE 161
CDF41533        89 TVILLGTFLA-ACLLGELIRFLG-G-YKSFLWNAAAFAAF-SLGMTGSPLPIWI-MRESFLTQISEQ-GMAE-SYVSTLR 161
CCY59675        89 TVILLITFAI-ACILAEVIRLLT-G-YDKFWGNAVAFACF-SLGMVGSPLPIWL-MKESFLAQISSQ-GMAE-SYVEALR 161
WP_015564603    83 LANLLLGSLIvCSILAEIIRKWA-G-YKNYKGIVMSYILL-SLSNIGSPLYVWV-FSDYAISEASEE--MSA-NYAEILS 155 Eubacteriales
jgi:Shel_28280  82 GFVVIIIALT---AIAEVIRALC-G-YSTLKGVRLSFIPF-AFSFYAYSAHWWTdTAGSLAAAVA---EMPA-GYADTMA 151
WP_012799882    84 MWHVVPLVVI--GLLAEAVRAVR---KYDWLGDVIATAVM-TFSTFGYYGQIWF--NRAYTYECAIE-EMPA-GYADGLM 153 Slackia helio...
jgi:Elen_3089  190 KYYgNAEWIVFIVALTAFAGFLGALVGKRLMRKhflK 226
jcvi:FSU_2178  163 ELSsSYWPLIGLFGFGAAGAVVGGFIARRMMKKhfeR 199
WP_012858701   154 RLI-TYPNMLLVYAGAIIGGIIGAYIGKLFLKKhfeK 189 Streptobacillus moniliformis
WP_009608046   173 ALS-TTPMLIAMFAVTIVAGLAGAYIARCLFKKhfeK 208 Eggerthella
CDD29051       162 ALS-STGMLVVLFLAPIVGAIIGGFIARAMFRKhfeK 197
CDF41533       162 ALS-SQGMLVVMIVAPVITAFVGAWIANGMFHKhfkK 197
CCY59675       162 NLS-STGMLVVLFLAPIVGAFLGALIAKGMFRKhfeK 197
WP_015564603   156 TLT-SPWFMVLAIAATVVISIIVGVIAKKVYNKqfan 191 Eubacteriales
jgi:Shel_28280 152 PVIdNTPMLVVMLILVIPVALLAIRLAEKVLKKqaae 188
WP_012799882   154 AAS-PAWSLPLVIVIGIVVSVAVAYLTAKLFKlekr- 188 Slackia heliotrinireducens
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