3EHM,3MX3,3CGH,3EJN,3IV0,3GZS,3FDH,3JYS,3I4G,3JQ0,3CK9,3L22,3LEW,3JQ1,3MCX,3MYV,3IHV,3HDX,3KEZ


Conserved Protein Domain Family
SusD

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cd08977: SusD 
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starch binding outer membrane protein SusD
SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.
Links
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Statistics
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PSSM-Id: 185760
Aligned: 28 rows
Threshold Bit Score: 125.995
Created: 15-Dec-2010
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3EHM_A    21 GPLKYGARFXNXQQRvipigspslttgpgndlqNTDLISSGNYIgyFGNnnnwgfnneanw--nftdsrxnyayQNFYSQ 98  Bacteroides thetaio...
3MX3_A    18 TKVTSSLLATGLLLDits------------ssaSKSFIYDELLAkqXAWgesxedyq---------ynvfgrsgFGGYTT 76  Bacteroides fragili...
3CGH_A    19 DGYALGSAXNNLAGCvvspd--------vntaqFTDCLLGGPLGgyFADsnagftetisnfnpkddwsrvflksDKIIPT 90  Bacteroides thetaio...
3EJN_A    15 TQTHPKLLLTQICXNa-----------------FKRGTDGXYATkkVIQadgesadq----------yykwtrgSFGYYD 67  Bacteroides fragili...
3GZS_A    20 DGVIYGAYLPNLEKSvipigtasestepvnryqIGVNLAGDAWAgyXSPrdnkfngsknftnyfxyenwvnyvySFXVTD 99  Bacteroides fragili...
3FDH_A    17 TSVASRFILADVITStafs-----------nasGDINTYASSYIeyEVGvdnqlyyaevre-nepsssstfnnsWNGIYS 84  Bacteroides thetaio...
ACY18602  38 TPTLVNLAATGLLAGsrleyg------fdngyiAHLSVLGREAYnlDVAdpryraellsgpgldpgspafggnlWNDPYA 111 Haliangium ochraceu...
BAH39247  45 DAGTVNTAVAGVLAGsraga---------gtwaSTLGVFGREIInlDGAeprnvlalligp--lepggfgvdvgWTNSYR 113 Gemmatimonas aurant...
EAU63727  47 TPAGVFSVATGLLIGnragvs------aqngyvAQLGILGRESFtlDPAdpryvtemvrgt-lnpgspafggsnWNAPYA 119 Stigmatella auranti...
BAH39511  46 NAALISSSAVADYECalgg-----------yavASGMAAGELFDatQTAarwsydrrnila--vdatyatatceGIGVFT 112 Gemmatimonas aurant...
3EHM_A    99 IFLPWNEIYEiakds-------dspseQAILEIANIVRNIAWLRATDvf------gPIAYNsagd-------gsiAPKFD 158 Bacteroides thetaio...
3MX3_A    77 LINAQKXVESvsd-----------dnvNAYDGLAHFIKAYKIFYXSXex------gDLPYEealqg----elglvRPKYN 135 Bacteroides fragili...
3CGH_A    91 LYSNLTQVKLvsqn----------tndPVPYAIAQVIKVAAXHRVTDaf------gPIPYSqiga------ngeiATPYD 148 Bacteroides thetaio...
3EJN_A    68 NLRNVQKXGEeaer----------vnaPVYTALTKFFRAYYFYELTLrf------gDIPYSqalkge---keeiyTPEYD 128 Bacteroides fragili...
3GZS_A   100 VYSPWXQIKRisqde--------gtrnDEIYALAQIIKIAALHRTTDxf------gPIPYSqvgk-------gsfKVAYD 158 Bacteroides fragili...
3FDH_A    85 SLKNARIIIDqcgegg------rdhgnDVTRGXAEVXAAYNCALIADff------gDAPCSqaalvdekgspvyxTPKXD 152 Bacteroides thetaio...
ACY18602 112 NIHNALNVLNavgkvda----yseqerEGLRGFAKTIEALDYFMIVNtrd----vnGGFIAtstd-------idvLPTPA 176 Haliangium ochraceu...
BAH39247 114 NLRTAYTILEvvdrvpd----ytaaqrSAVKGFVKTFIAQEYVNQLRvrd----tfGLVFDvpkd-------paeQGAFI 178 Gemmatimonas aurant...
EAU63727 120 NIRNANTLLSmvdkvsg----ltdaqkEATRGFAKTIQAIDFLVAINtrd----enGAPIDvggd-------iteLAPIE 184 Stigmatella auranti...
BAH39511 113 PINTARYTNDqavtkleewsdaqvpnrQRMIALNSAIAGFSLVLLGEgfcsgtinvGATLTp-------------TQLFD 179 Gemmatimonas aurant...
3EHM_A   159 SQEVVYRSXLADLSKSVELLntisysvxaqy---dliyngnvqnWVKLANSLXLRIVVRVhfid----etlAKEYITKAL 231 Bacteroides thetaio...
3MX3_A   136 TQKEVXNFILSDLETAYELFstakdfdgd------pilggsiskWKKATTAFQLKVLXHLskkesdadlkvKERFARIVA 209 Bacteroides fragili...
3CGH_A   149 SQEVTYNTFFDELNAAIATLnensneqlvpt--adyiykgdvkkWIRFANSLKLRLAIRIayan----pvkAQQXAEEAV 222 Bacteroides thetaio...
3EJN_A   129 AQEDVFAGILQELREADEILandasvidgd-----iiyngnstqWRKLINSFRLKVLXTLsnhttvgniniASEFKNIAT 203 Bacteroides fragili...
3GZS_A   159 SQESVYRSFLKELEEAVQTLddysnkskevlpafdivyngdvnkWXRFANSLXLRLAIRVrfad----aglAKEYAEKAV 234 Bacteroides fragili...
3FDH_A   153 TQQEIYTQIISYLDDAIANLqkedladvteq---dflyagdadkWLKFAYGLKARYTXRLinrss-nksadYEKVLDYVS 228 Bacteroides thetaio...
ACY18602 177 SKDELHEHIASLLDQGAGHLdnagdaftftfs-sgyagfdtpssFRSYNRALRARVAAYQe---------dWDGVLSALA 246 Haliangium ochraceu...
BAH39247 179 TRDEAYTKTAALFDEARADLaaggtafpftlt-tgfagfntpptFLRVNRGLKARMETYRg---------rWADALTAVN 248 Gemmatimonas aurant...
EAU63727 185 PKAVVFTHIATLLDEAKAHLtaggtafpfpls-sgydgfdtppdFIAFNRALKARVEVYRg---------nFTSALTALD 254 Stigmatella auranti...
BAH39511 180 SAEVRFTKAITAATTANDAA------------------------ILNLAYAGRARARINKan--------kPGAAEDAAR 227 Gemmatimonas aurant...
3EHM_A   232 DPknggv----iediSSEAKIKSsdkxpllnSXLASvn---------------eyNETRXGATIWGYldgyKDPRLSAyf 292 Bacteroides thetaio...
3MX3_A   210 SGslx-------esnEDNLQXKYadkantvyPFHNTntk--------------haGYAXLSTXLIDKfkatGDIRXFYya 268 Bacteroides fragili...
3CGH_A   223 NPanggv----iesnADNATWNYfet--sqnPIYVAtrynqvqtsdhggvpcltgGDTHAAADIICYxngyKDNRREKff 296 Bacteroides thetaio...
3EJN_A   204 NSplx-------nslADNGQLVYldqqgnryPQFNAq-----------------wSGYYXDDTFIQRxrerRDPRLFIfs 259 Bacteroides fragili...
3GZS_A   235 KHpagl-----inskELAAQXGKgaglqxknPLKVIne---------------eyNDTRXGATIYSYlagyNDARAAVyf 294 Bacteroides fragili...
3FDH_A   229 KSft---------saDDQAAFDIydsn-ninPFYGFyn---------------srAGFGASTSLGTKllayNDPRANRaf 283 Bacteroides thetaio...
ACY18602 247 DSfldtsd--tasmnLGVYHSFStqsgditnQLVSNn------------------LYGHPTLATDVDp---DDQRFAQkl 303 Haliangium ochraceu...
BAH39247 249 ESfistasgtaaalnTGIFHVYStasgdavnPLFDPtpr-------------alvAVPEFLTEARNRadgsRDLRASSka 315 Gemmatimonas aurant...
EAU63727 255 ESfldla----apleLGVYHTYStssgdatnALFSNgn---------------iiANPLLVTEAERKltgdVDDRVTRki 315 Stigmatella auranti...
BAH39511 228 VPv------------AFVYNATSdatvgrrnNRMFQq------------------NNQSFSVTIATAyrtlNDPRVSLtn 277 Gemmatimonas aurant...
3EHM_A   293 tegtygsgswaqtgyfpvapt---------nsksksetsysakfasrpkvdsnSPLYWFRASETYFLKAEAalyn--lig 361 Bacteroides thetaio...
3MX3_A   269 kpakaklnegvtadswdayigtdpslpfeqiekayateqysgfnarytdypsgEPVVRLGYAEQNFILAEAavrg--wis 346 Bacteroides fragili...
3CGH_A   297 tksewagqdyvgxrrgiv----------------ipelkttghkysgvniaptSPLYWXNAAEVAFLRAEGqavfnfsxg 360 Bacteroides thetaio...
3EJN_A   260 aqtnkgktegkpiddfssyeggdpaapysdaiikvsegtispindrfrtdpivEPTXLXGYAELQQILAEAvvrg--wis 337 Bacteroides fragili...
3GZS_A   295 vknngfkavrcgiak----------------------sgdayngftrpnvhedDPLYWXKASEVXFLKAEGalag-fdxg 351 Bacteroides fragili...
3FDH_A   284 ftpivdkkrsqvaandpslvp---------apngspdqstskygisafvyaktAPTLLXSYHELXFLKAEAlcr----ln 350 Bacteroides thetaio...
ACY18602 304 aqvdsrtldgl-----------------------------tsdlqftvydstsAPVPIIRNEELLLLSAEAklrt--gdl 352 Haliangium ochraceu...
BAH39247 316 vvgtvnvttqgi----------------------------ssnvrptvyptnvTPVPIIRNEELILIRAEAnigl--gnr 365 Gemmatimonas aurant...
EAU63727 316 gtlekevkydda---------------------------irstyefilydsasAPIPIIRNEELILLRAEAnigl--gni 366 Stigmatella auranti...
BAH39511 278 qnrlasdqvn-------------------------------qlwtqnkftsltASYPIASGIESQLILAEArg------g 320 Gemmatimonas aurant...
3EHM_A   362 GDPKTFYEQGINISfqeqgvsgvatylsgtgkptgltgsnykygtynhdlsigntspkwddytgnlskqeeqLQKIITQK 441 Bacteroides thetaio...
3MX3_A   347 GDASAYYKKAIRAHxefiasntpdeevyhhghpite---------------eaiaafletpaiqlsgekeedIEKILTQR 411 Bacteroides fragili...
3CGH_A   361 GTAESFYNQGIRLSfeqwgadgvedylkddvnkptaytdp------agtntyqnalsnitikwndsadkeekQERIIVQK 434 Bacteroides thetaio...
3EJN_A   338 GNAQTYYEKGIRASfsfyethakdyagylnenav------------------aqylkeplvdftqasgteeqIERIIXQK 399 Bacteroides fragili...
3GZS_A   352 GSAGDFYNAGIRXSfsengldnssaetylkdstrkpanytd----tsngelsanapssitirwengateeekLERIITQK 427 Bacteroides fragili...
3FDH_A   351 RDAEDALKEAVVAGllnaensisiaikelgsglntnss----------evitetsagkyfddvvkakyaanpLQETXIQK 420 Bacteroides thetaio...
ACY18602 353 AGAVADLNIVRQQSagqdalva------------------------------------------ddldadavFEELVYQR 390 Haliangium ochraceu...
BAH39247 366 AAAITDLNFVRTNSgglpala--------------------------------------------sdfagdlITELLYDR 401 Gemmatimonas aurant...
EAU63727 367 PTAAEDLNFIRVTSggltare--------------------------------------------ditaanaLDELLRQK 402 Stigmatella auranti...
BAH39511 321 AEGIAILNALRARTgvalpalt-------------------------------------------aqetanfNEAVAEER 357 Gemmatimonas aurant...
3EHM_A   442 YLALYPNAv---eAWTEYRRTG 460 Bacteroides thetaiotaomicron
3MX3_A   412 YLASFXQHpy--dVYYDYRRTG 431 Bacteroides fragilis NCTC 9343
3CGH_A   435 WIANWQLGn---eAWADFRRTG 453 Bacteroides thetaiotaomicron VPI-5482
3EJN_A   400 YLVTFYQGnw--dSFYEQLRTG 419 Bacteroides fragilis NCTC 9343
3GZS_A   428 YLAIFPNGq---eAWTEWRRTG 446 Bacteroides fragilis NCTC 9343
3FDH_A   421 YLAXWGASgeateTYNDFRRXK 442 Bacteroides thetaiotaomicron VPI-5482
ACY18602 391 RFGLLFEGh----RWIDMRRWG 408 Haliangium ochraceum DSM 14365
BAH39247 402 RYSLFFEYg---hRWVDSRRYN 420 Gemmatimonas aurantiaca T-27
EAU63727 403 RYSLLFEGg---hRWIDLRRYN 421 Stigmatella aurantiaca DW4/3-1
BAH39511 358 RRELFLQGn----RWFDVRRFN 375 Gemmatimonas aurantiaca T-27
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