6Q56


Conserved Protein Domain Family
TrmK

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pfam04816: TrmK 
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tRNA (adenine(22)-N(1))-methyltransferase
tRNA_MT is a family of bacterial tRNA (adenine(22)-N(1))-methyltransferase enzymes with a Rossmann-like fold. This enzyme carries out the function of N1-adenosine methylation at position 22 of bacterial tRNA.
Statistics
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PSSM-Id: 428139
Aligned: 11 rows
Threshold Bit Score: 229.509
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6Q56_B    23 MADIGSDHAYLPSYAVLNHKASGAIAGEITDGPFLSAKRQVEKSGLNSHIsvrQGDGLEVIKKGE-A-DAITIAGMGGAL 100 Bacillus subtilis s...
P75427    20 FYDIGCDHGYLARELVQQNPSLVGVNSDISANALGAAKGLLKDHTNMHFI---TSDGFDLLPNLNlDpAVGVIAGLGGLK 96  Mycoplasma pneumoni...
Q9RXN4    22 HADIGTDHARLPLRLVRGGRVSRCVAVELNPGPLALARRMVARARLTEQIdvrQGDGFAPIQPGE-L-GSASVTGMGAYT 99  Deinococcus radiodu...
CAC99531  23 IADIGSDHAYLPCFAVKNQTASFAIAGEVVDGPFQSAQKQVRSSGLTEHIdvrKGNGLAVIEKKDvI-DTIVIAGMGGAL 101
Q9KD40    23 LADIGSDHAYLPCYLCLKGVVEFAIAGEVNEGPYQSAVEQVQKVNLGHVIsvrKGDGLAVIRADDqI-DTVTIAGMGGTL 101 Bacillus halodurans
Q9CGM4    23 LADIGSDHAYLPTYLMQKLVIDFAVAGEVVKGPFEIAKNHVSEADLSDRIevrLANGLGAIENTDkI-DTIVIAGMGGIL 101 Lactococcus lactis ...
Q8DNY3    19 LLDVGSDHAYLPIELVERGQIKSAIAGEVVEGPYQSAVKNVEAHGLKEKIqvrLANGLAAFEETDqV-SVITIAGMGGRL 97  Streptococcus pneum...
Q8DT98    27 LLDVGSDHAYLPIYLLEQGLIDFAVAGEIIKGPYESAVANVSESELSGQIavrLADGLAALNDNDdI-DLITICGMGGRL 105 Streptococcus mutans
Q2FY13    20 IADIGSDHAYLPIYAIQNHLCECGIAGEVIQGPFQAAVKNVAANQLVDRIdvrLGDGLSVIQPEDvI-DNITICGMGGPL 98  Staphylococcus aure...
Q9PQE1    20 VVDVGSDHAYLAKILLVNNKAQHVTNIEVNQGPLENGINNLTKNNLLKRTtniLNDGFKGLILEQtF-DYCVIAGMGATS 98  Ureaplasma parvum
Q97JI1    20 AADIGTDHAYLPIYLIKNNLCKRFIASDVNAGPLKKAINNINKYKLEDKIecrLGSGLNVLKL-EeV-DVVVIAGMGGNL 97  Clostridium acetobu...
6Q56_B   101 IAHILEAGKDKLtgkERLILQPNIHAVHIREWLYKERYALIDEVILEEDGKSYEVLVAEAGDRDAay-dgISLSAGMLVG 179 Bacillus subtilis s...
P75427    97 IMQILAQHNNFL---KHFVLQPQSNIIELRRFLSANQWTITTETLVEERGFIYLVLAVDKTKAQTq----YLTEEQMILG 169 Mycoplasma pneumoni...
Q9RXN4   100 IRGILDRAGERLpp--aLVLQPNDSPLWLRTWARENSYHLRAERLLPG-YWAYPVLRLERAEGPDpayadLPAAAALRYG 176 Deinococcus radiodu...
CAC99531 102 IRTILEEGAAKLagvTKLILQPNIAAWQLREWSEQNNWLITSEAILREDNKIYEIMVLAPSKKPVa----W-TKQEIFFG 176
Q9KD40   102 ISTILEEGKRNLqtvRRLILQPNVHGKAIRQWLSDNGWRLQAEAILEEDEKIYELLIAERGSDEDl---yVSKELDLLVG 178 Bacillus halodurans
Q9CGM4   102 ISEILEAGKEKLghvKRLILQPNNHEESLRQWLVNHQFVIKKEEILLEAGKFYEIIVAEPLSKLMt---eKLSVNDLTFG 178 Lactococcus lactis ...
Q8DNY3    98 IARILEEGLGKLanvERLILQPNNREDDLRIWLQDHGFQIVAERILEEAGKFYEILVVEAGQM-------KLSASDVRFG 170 Streptococcus pneum...
Q8DT98   106 IADILAAGSDKLnsvKQLILQPNNCEDDLRSWLVANDFMIKAEKMVKDRHKYYEILVVEKGKI-------TLSDKDLRFG 178 Streptococcus mutans
Q2FY13    99 IAKILKDGQDKLsqhPRLILQSNIQTENLRQTLQQLNYEIIDEIIMEEKGHIYEIVVAEYSTELIe-----LSSDELKFG 173 Staphylococcus aure...
Q9PQE1    99 IIEILEQNKNQi---KNYILQPNTQSYKIRKYLNNHSYQIKVEHIFVEKKIFYEIIICSKTINVP-----KLIEKDYYIS 170 Ureaplasma parvum
Q97JI1    98 IRDIIEERLDIFkklKYAVLQPVQNPEILREYLIKRGFNIIEEQLCIDESKYYEIIKVCYDSKIEd-----kDDVYYEIG 172 Clostridium acetobu...
6Q56_B   180 PFLAKEKNAVFLKKWTQELQHtqsiyeq-isqaadTEQNKQKLKELADRM-ELLKE 233 Bacillus subtilis subsp. subtilis str. 168
P75427   170 PHLVNFTDKQMLVKYYNGLLK--------------NFTARLNPSQFDSQViHVLNK 211 Mycoplasma pneumoniae M129
Q9RXN4   177 PLLLRKGPALLRARIEADIERltpv-------aapGREAWAELAAAREALaVVDAG 225 Deinococcus radiodurans
CAC99531 177 PCLLKDQSAIFKSKWRHEANTwqniiqtisnnqpvSPENQAKIRELEHKI-ALVEd 231
Q9KD40   179 PYLRKERNAAFQKKWTAELISwkrvlsq-lnkakpSEELEAKKIELQKNI-SLIEE 232 Bacillus halodurans
Q9CGM4   179 PFLSKEKSTVFQQKWQKELNTlnkii-----arlpEEQAE-KRQEVLNQI-ARIEE 227 Lactococcus lactis subsp. lactis
Q8DNY3   171 PFLSKEVSPVFVQKWQKEAEKlefal-----gqipEKNLE-ERQVLVDKI-QAIKE 219 Streptococcus pneumoniae R6
Q8DT98   179 PFLRQERSSIFKERWRKELAKlelal-----tkvpAKK-KADNMFLSTKI-EQIKE 227 Streptococcus mutans
Q2FY13   174 PKLLNNKNEYFIKKWQRELEAlyhik-----sklnTEQHHQRLAQINDEI-AVIEr 223 Staphylococcus aureus subsp. aureus NCTC 8325
Q9PQE1   171 SQMHKDSLNLYFKFLKRRYEYlkald-----islvSENIVKEYEYIKEFInEKNGY 221 Ureaplasma parvum
Q97JI1   173 DKLIDMKHPLLKEYINYKIRKydkiyk---niseeSLNALSRKNELSIKI-RKLKE 224 Clostridium acetobutylicum
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