296316036 2 ALGRLEFACLGVDIHAVADRVFVPDERNFI-----APAFPLRFWDEPVFAQAGDADA-TARELAAarARNRAAAAAADNL 75 57790950 2 FRPRFEPMNLPKDSNKPSTLMVLADRLNFIscaegSSKYASKLFEGTLIDAEIMTNR-ARIEDLE--RRNRAAKAALEQL 78 51557516 2 DRAWFAFE----------AAAIPGSARHFI-----APPFPVGFWARPGFSEGLD----ARLALAHanARRRAAAAALDNA 62 9625909 1 MTARYGFGSISFPNK---CGIFLSTTKNFI-----APNFPIHYWTAPAFELRGRMNPdLEKNTLT--LKNAAAVAALDNL 70 9629763 1 MAEYVDYVFGSLYVCDTARSTIPTDVRKFI-----APPFPLNFWSAPTFTASSNPRA-DPTKLVA--ARHRAAAAAIDTL 72 12084853 2 SRDMVNFIWGARIMGNDHLESHPADTKNFI-----APRWPIQFWKDPAFTDECGALE-KQLALVT--ARNKAAAAALDDL 73 13242427 1 MAKIYAFESISLPYG---CEIVLPHSNNFI-----APNFIPSYWTEPIFTERQRSENgFDIDVMV--NRNAAVSAALDNF 70 10834895 1 ---MASFAWDARILTDPGPESHPADVKNFI-----APPWPLHFWREPIFSGNLGDAE-RQLAIVK--ARNSAAIAALTSL 69 125745076 1 ---MANFIWDARILTGDGMEMFPADVKNFI-----APPWPIEFWKEPVFTSNRANME-RQLAIIT--ARNNAATAALNNL 69 255683189 1 -MERFFFSPLDMCKEHSSAGYI-SDSRNFI-----TPNWPAHYWTKSQANRHEEETAiQKLRILQ--QRNTAASAALDHL 71
296316036 76 LARQRATGAEVDARIRPIEARVAEVAAVLADLEEAARRAEEADAAAAAesaaragraGEGEDGDCGAGALGaleaARPRR 155 57790950 79 ENMSATVPVHVSSALQTIEYPLETVIDVLDDLAQRAVQEKDIVGSYKT--------------LDIRAPGED----VPANV 140 51557516 63 MAAGARLEAEVDEQLRPLERQVERVAEALVVLEETARAAEEADAARAA-------------EEAPEATAAA----DEGRE 125 9625909 71 RGETITLPTEIDRRLKPLEEQLTRMAKVLDSLETAAAEAEEADAQSEE-------------CTRTEIIRNE----SIHPE 133 9629763 73 EAQSQYSSANVDALIRPLERQVAKVADALAALEDAARAAESADAATPQ---------VNASDSDQRDNNVA----QSLSE 139 12084853 74 DGRTNTIAVEVDRRLRPLEDKLKEMASTLADLEQAASAAELADAAADAe-------lPASVSSEPRKDDSC----AENRI 142 13242427 71 RTEACKIPSEIERRLKPLENQIKEMAKTLDELETAAVEAEEADADIMC--------------NDTGSFKEH----TLHKE 132 10834895 70 DDRTDLIAVEVERRLRPLEDKMEQIATTLADLERAASAAELADAAADEa-------qNVVDSNECQKNIGS----AASRE 138 125745076 70 DGHTDSIAIEIDRRLRPIEEKIEHIATALADLEHAAAAAELADAAMDIav------sAVEKSGQHKEDVNI----TSARE 139 255683189 72 SIKNNCISAELEMRLKPIEEQVKSVTAVIADLENAAAMAEATDAADEIdgsyersrqDGDGDKLGETSDSN----DERRE 147
296316036 156 VQIAKNDPPLEYDTTLAADLLAMVYTARAGGGSA--GIVFGTWYRTLQDRLIAERPLATRGMD-YRDGRMSRTFMAAAVA 232 57790950 141 IWIVKNGEPLTFNTDFQVDFLTTSFAIAGNG-----RLGFGSWFRALQTQLLDNNKAIARVLNvMGDTRISGRFMKTAIR 215 51557516 126 VQIAKNDVALAYDANLSLDFLAMVYAARGAAS----GVLFGTWYATLQATLVAERPQVSRAID-SRDGRMSRTFMGVTTT 200 9625909 134 VQIAKNDAPLQYDTNFQVDFITLVYLGRARGNNSp-GIVFGPWYRTLQERLVLDRPVAARGVD-CKDGRISRTFMNTTVT 211 9629763 140 IQIAKNDVPMEFDTNLAVDLLTTVFVGRAAGGSN--GVVFGTWYRALQDRLVTERPVATRSID-YRDGRMSKTFMSTAVV 216 12084853 143 VKIAKNDPALRYVSNLPVDLLNIIYASRGAASA---GVLFGTWYRALQNMVITERPHVARKID-YHGGRMSRTFMTTVVT 218 13242427 133 VQVVKNDAPLQYDTNFQIDFLTLVYVERSRGNSMp-SVVFGPWYRTIQERLIIERPIAARSID-YRDARISQTFMNTAIT 210 10834895 139 VQIVRNDPSLRYDSNLSVDLLNIIYASRGAANS---GVAFGTWYRTLQNSLIAENPSAARKID-YRDGRMSRTFIATAIT 214 125745076 140 IQIVKNDPLLRYDSNLSVDLLNLVYANRNVVNS---GVVFGTWYRTLQNALVADKPSVARKID-YHGGRMSRTFIVTAIT 215 255683189 148 VQIVKNDTPLRYDTNLSTDLLTIIYSTRGGSSASgwGVLFGTWYRALQDGLITEWPVVSKRLD-QRDGRQSKTFMTTAIV 226
296316036 233 ALQSSGRMYVGNRAYSAFECAVLCLHLAHR----ATVGGARS-PVTFV----GLVEQLPAYLDALARAIDEGAaRRVQYA 303 57790950 216 ALRSAMEIYAGTRQYSGFEATVLCLLHYSRsrqsASNIRHGLdVSIFE----DALRHVPTYLNYMLEDIRAEW-GSVTFS 290 51557516 201 ALQACGRLYVGNRHYSALESAALCLHLVHRvrqgAGAAGAAA-PLGIA----DLLERVPEYLDALSQALAEG--GRISYR 273 9625909 212 CLQSAGRMYVGDRAYSAFECAVLCLYLMYRt---SNSVHEPQ-VSSFG----NLIEHLPEYTETFVNYMTTHE-NKNSYQ 282 9629763 217 ALQSCGRLYIGNRPYSAFEAAVLCLHLAHR----AVNSNFSY-PTSFS----GLIEQLPIYIEALSASLEDGAiGKVVYE 287 12084853 219 ILQSCGRLYVGKRQYSSFECAVLCLYAFFV----KTGHVDSH-PSNFT----TAIESVPTYLDHLASKIVEVD-YKPKYG 288 13242427 211 ALQSCGKMYVGERLYSAFECAVLCLYLVHRe---LSVITPHT-PVTFK----HLINQLPDYVETLSSHSNLR--NARSYH 280 10834895 215 SLQSCGRLYVGTRNYSSLESAVLCLYAFYT----KTGANVSH-PSSFK----SALESVPIYLDHMSASLASTD-TRQIYG 284 125745076 216 SLQSCGRLYVGTRYYSSLECAILCLYAFYA----KTGTNISH-PTNFM----SAIESVPTYLEHLSTRLASSD-SRQKYG 285 255683189 227 SLQATGRLYVGVRHYTALECAILCLQLHHRi---TSAKTKCQ-PFNYAssaiGMVEQLPAYLDNFIERLASDC-GRLCYR 301
296316036 304 FDFERLPRGQFQAPGGgaGRYERGALEAHAVVAALQRLRVLPAIPGALGGGAALa-rAADADGVAYVDDVHRAAGAFL-A 381 57790950 291 FDRSKLPVNFFSPIDG--RKYSNGVFDPHIVYQLLKRTGTLSTTVRDITKETLL---PIDPDFVRFDDPIAALSISFFpS 365 51557516 274 YNYPRVPREQLH------GRY---ALEGHSVLAALARLRVVPGANVG----------ANEVDGAGFVDEVNRAAAAFL-G 333 9625909 283 FCYDRLPRDQFHARG---GRYDQGALTSHSVMDALIRLQVLPPAPGQFNPGVND---IIDRNHTAYVDKIQQAAAAYL-E 355 9629763 288 FNGARLPKNQFHVPGGg-GRYERGALNGHSVLETLIRLKVLPAIPGSLGTTNTAigpELDVNQTAYIDDVNKAAAAFL-V 365 12084853 289 FDAKRLPKDYFEPPS---GKYERDALIDHSVLKVLVKYRVLPPAMGSIPRGCIIe--DVDKNQTAYDDDVNSAAAALL-G 362 13242427 281 FSYEKLPKDHFHAPSG--GKYEFGALLPHVILTTLTDLQILPPAPGQFPHGKITs--IVDKDKNVYVDKVQRAAATFL-Q 355 10834895 285 FDTGKLPKDSFAAPS---GKYERGALSDHSVLRALANSRVLPPSAGSIPRGDVAp--ELDADQSVRNDEVNAAAAALL-G 358 125745076 286 FDWARLPKDTFDSPC---GKYERGALHDHSILRALVNSRVLPPGAGSLPRGDVIp--EIDAEQGIRNDEVNRAAAALL-G 359 255683189 302 FDMDRLPKGQFAIQP---RSGERIALSGHCVLAMLIKHGVLPLSPGVAAPDGLAr--DVDKSQRAYVDEVNKAAGAVF-G 375
296316036 382 RAQNLFLAEDQSLLRATVDAITALLLVRRLLWNGNVYADKLRNNFQIGTL------------------VPGAAAPG---E 440 57790950 366 RRTPLILHEDDPLVRTVIDSISLLLVLQKLMFNSNVYTSTHLNRFQPSAFfelplgtqseqeaakwpvAPGSRP-----Q 440 51557516 334 RGQNLFLGEDAPLLRATVNTITGLLLLRRLLHNGNVYGDRLRNNFQLGAL------------------VPNAPPPR---- 391 9625909 356 RAQNVFLMEDQTLLRLTIDTITALLLLRRLLWNGNVYGDKLKNNFQLGLI------------------VSEATGTPtnnV 417 9629763 366 RAQNLFLTEDQTLLRSTINTITALLLLRRLLWNGNVYTDKLRNNFQLGAI------------------VPNLSVAL---G 424 12084853 363 RAQPLFLMEDQTLLRSTLNTIASMLFLRRLLWNTNIYSAKINNLFQLGSF------------------VPGTVS-----S 419 13242427 356 RAQNIFLMEDQSLLRLTINTITTLLLLKRLLWNGNVYGDKFKNNFQLGLL------------------VMGAADKAkedL 417 10834895 359 RAQPLFLMEDQTLLRATLDTIVALLLLRRLLWNTNIYSARVKNQFQLGAF------------------VPGVPP-----D 415 125745076 360 RAQPLFLMEDQPLLRSTIDTITALLLLHRLLWNTNIYSARVKNIFQLGAF------------------VPGIVP-----D 416 255683189 376 RAQPLFLMEDITQLRATINTITSLILMRKLLWNTNVYADRMCNNFQIGTL------------------LPGAVPSD---R 434
296316036 441 VARGADGGPDGAVg-aRSGDANLTFLCTRYVARVYEACPEVEVTQLFPGAAALALD-----ALAPRSAAGAPRAISVAGG 514 57790950 441 ATASTFDDNGQDM---ASRDNNLFFLFEKYVVPMYRYDNRCEVTGFFPGLAALCIT-----------GRVKGIPTAVRLG 506 51557516 392 ---GASGDAPAS----RSGDGNLRFLLAHYVVVAYRADERTELTQLFPGLAALALD---------------AHSIRARVQ 449 9625909 418 ILRGATGFDGKF----KSGNNNFQFLCERYIAPLYTLNRTTELTEMFPGLVALCLDa----HTQLSRGSLGRTVIDISSG 489 9629763 425 NARGAIGGDASAMv-sRSGNNNFTFLCSHYVSPIYLANTEVEITQLFPGLAALCLD-----AQTGARNHPHHRAVNVSTG 498 12084853 420 VAVGASVATPESAi--RSDGRNLLFLFQKYVAPIYNAIKGVELTQLFPGLVALCLDvpffvTGMSDHKQPPARIIDTSLS 497 13242427 418 LLRGATGNDSKI----KSDNNNFRFLCENYILPLYVANPTTEITEMFPGVAALCLDa----FGQLHHGTLGRVVIDISSG 489 10834895 416 LTVGASVDTPGDVi--KSDGRNLTFLFQRYVVPVYSVVKGIELTQLFPGLVALCLDvpfsdRGLYSTRTPPSRIIDVSLS 493 125745076 417 LTVGASVDTPGDIi--KSDGRNLMFLFQRYVAPMYGTVKGIEFTQLFPGLVALCLDvplfsGGIFSHRAPLSRVVDVSLG 494 255683189 435 LNRGASNGGAAGAqtmKSDNRNFAFLCERYMASLYAADPQTEITQMFPGLVALCLD-----ARNIKTQNATRHVLDVSTN 509
296316036 515 RHQGGLLRLVALELENRHR-AAPAPVVEVVAAHDAVALQYERGLGVLMQQPRLRRALDETRRLSQFNVASDYDLLYFLCL 593 57790950 507 EYYSSLCNLIELDLRKTSH--VGSGAAAVLAVHDSLTGDVEEGVSRLLEVFDAKKAFERN-------------------- 564 51557516 450 RHQLNLVRLVALELQNRQR--VTAPVNEVIAAHDAVAVQYEEGLGLLLQQPHLRNA--ADKRLGQFGVSSDYDLLYFLCL 525 9625909 490 QYQDRLISLIALELEHRRQnVTSLPIAAVVSIHDSVMLQYERGLGMLMHQPRVRAALEESRRLAQFNVNSDYDLLYFVCL 569 9629763 499 RNQTNLTRLIGIELENRRK-TAPAPINEVLAAHDAVALQYERGLGLLMQKPRLRASLEETKRLGQFNVASDYDLLYFVCL 577 12084853 498 KYQTTVAKLVSLELENRNR-GNVASIKEVIAAHDSVTLQYEHGLELLMQIQQPRARLFESRKLIAFNVQTDYDLLYFACL 576 13242427 490 QYQDQLMRLIALELENRRKpATSVPVTSVILAHDSVMLQYERGLGLLMQQTRLRMILEESRRLAQFSVNSDYDLLYFVCL 569 10834895 494 KYQASLVKLISLELQNRSR-ANVVSVCEVIATHDLVTLQYERGLESLMQVQRPRTRFFETKKALAFNVETDYDLLYFVCL 572 125745076 495 KYQASLVKLISLELENRSR-ANIVSVCEVITAHDLVTLQYEQGLESLMQIQRPRSRLFETKKLSAFNVETDYDLIYFICL 573 255683189 510 RAQAALLRLIAVELQNRSK-TISVPIQEVLTTHDAVALQYEEGLATLMQQARLKNTLSDGRRLLQFNVNSDYDLIYFLCL 588
296316036 594 GFVPLFTSAV 603 57790950 565 --IEDIQRGV 572 51557516 526 GYIPQFAAA- 534 9625909 570 GVIPQFASTP 579 9629763 578 GYIPSFTSAM 587 12084853 577 GYIPKLVSAP 586 13242427 570 GFIPQFTSVA 579 10834895 573 GYIPRSVSAS 582 125745076 574 GYIPKLISTL 583 255683189 589 GYIPLYASSM 598