6FXE,4ALY,4BG5,5IZT,4B2F,6ROC


Conserved Protein Domain Family
PFam54_60

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pfam05714: PFam54_60 
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Borrelia Bbcrasp-1 domain containing protein
This family contains lipoproteins from the Lyme disease spirochete Borrelia burgdorferi and related bacteria. This entry contains proteins from Paralogous family 54 (PFam54) and 60 and (PFam60). The first crystal structure of B. burgdorferi PFam54 member BBA68 revealed a previously unseen novel fold, which, according to the CATH protein domain classification, was named the Bbcrasp-1 fold because of the common name used for the protein BBA68.
Statistics
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PSSM-Id: 428601
Aligned: 43 rows
Threshold Bit Score: 78.5423
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6FXE_A        35 KKLE-EEPSNQYGIS-IFKEI--YWVAs---------YETVADNTDRSKNYRKFTYATLNpINTNKLANLSKILIQ---- 97  Borreliella bur...
4ALY_A        94 SSRG-E-PNDQFGMRaEIFSK--IFFNa---------NSTVHFDSHEYTEERRMLYTSLN-FNEGKIFNLGQILSKlsqd 159 Borreliella bur...
4BG5_B        66 KEKLqTEIPSQFGLKnSMFEL--LNVYkidstngtrlQEKMNSSLAESQKMRRQFYSSLS-YNTTDIFNLAEIVNKlykd 142 Borreliella bur...
ETZ17863     102 KYSNkIEDNEQYGMKwGVFKF--LIED----------NNKRNIQAVENMPARKQLYASLE-WNEDRLRKFGTIMNEvek- 167
4B2F_A        29 QKIE---PNDQFGINkTLFTE--KKDN-------------NIDFMLKDNRLRRLFYSSLN-YDENKIKKLATILAQtsss 89  Borreliella bur...
WP_038366914  76 EQDIiRESVKQLGIQcTIFDE--VYYDs--------lIHKTGKTYSIDKNKIKLFYASLN-YNIMRLKWLGDILLQiqkn 144 Borrelia duttonii
6ROC_B        16 KELEdRKNQYDIQIAkITNEEsnLLDTy--------iRAYELANENEKMLLKRFLLSSLD-YKKENIETLKEILEKlinn 86  Borreliella bur...
O50891       115 EAQKkKEDTGITKMSkIDNAKydFLETfk-------lKQDDVFMFHAKMKLKRIIYPSLN-YDTKKILVLKEILEKldte 186 Lyme disease sp...
O50889       107 EAQKkEKDTQIEKISsDAQYD--FLENfk-------lHNYDYFMHNTKMTLKKIIYSSLN-YEKEKILTLKEILEKldte 176 Lyme disease sp...
ETZ17866      93 KDGK-EPDNTQYGLKdTVFKI--IKDD-----------KNKTYDEDTNKDTRHQFYGSLS-WKKETIEGLGEVLAKlaee 157
6FXE_A        98 ------SKQKTLLFGTFCNLGRTFDTAINHLYPKKDAL-DKLEIS--NLEKLKNSFEKLLSMKSIVSDMLNQLLLDYQDD 168 Borreliella bur...
4ALY_A       160 --snyrGLVKETLINRGFSIQLAMEEISAKILNVKDKL-QQLNKP--NLETLYNDFEKLTSLKEKWLKDTDDLIDEYNTN 234 Borreliella bur...
4BG5_B       143 --pkahDTIKKISGGIR--IQQGFEVALEDLAINMDKL-KANDFNknTLEEIYNLIVDLTLIKKEWLSTIETLIKSSNAT 217 Borreliella bur...
ETZ17863     168 ---cdrVVATTILETGMNFVQGKFENAIISIDDKDQDL-DNLILK--ELKDIKKNLDLIDSFRKQWISSVDSIISEYDSN 241
4B2F_A        90 n-dyhyTLIGLIFWTGFKIQEAFESAVNILTKDEQKRLiFNFRTK--TVKEIQENFEKLMQERNSWIKIVDNIIGEYDKN 166 Borreliella bur...
WP_038366914 145 ntkqgnKLYNAIIETGREYSQKPFEEIIHEVNKEQNKL-ILLKSD--KLKEVMDNLNIIKNLRMMWIKFIDIIIEDYRKN 221 Borrelia duttonii
6ROC_B        87 y-endpKIAANFLYRIALDIQLKLEKHLKSINEKLDTLsKENSKE--DLEALLEQVKSAMQLQEKFKKTLNKTLEDYRKN 163 Borreliella bur...
O50891       187 --dnnrRIAGQFLETSR-DIQLHLEDTY--LKKIQDTL-QTLSEK--EAEKLLQGVKLDLKKKQNFAKSLNATIDAYNKN 258 Lyme disease sp...
O50889       177 --dnnrRIAGQFLETSR-DIQLQQEDLI--LKKIQDTL-QTLSKE--KAEELLQHAERDLKIKQNFVKALNATIEAYNKN 248 Lyme disease sp...
ETZ17866     158 a-tykdTWPKKLVDVGAKVQGVIQV-TFKQIEDKKDNL-NTLSLE--KINELNDQVKKLEEARTTWITFVSDLIKDYKDD 232
6FXE_A       169 KDSIKTD-IAKLESHLTELYKQ--IE-KKSSQAT-KLKNNILSISN 209 Borreliella burgdorferi B31
4ALY_A       235 PD-LQTD-VSKLNDTLRSKNSRaqFA-NIHDIIL-DLVNTTTNILA 276 Borreliella burgdorferi B31
4BG5_B       218 LELQYNT--EKLNDHIEQTYKDtmISlCLKSEQT-LLHLDTLFKFN 260 Borreliella burgdorferi B31
ETZ17863     242 TGDIQKD-SQALVNRVNTEYKE--IFeNKIDEIK-KAVDDIQTILK 283
4B2F_A       167 TGGCKAD-GKILGEVIRVGYEHe-LDsNKSMQILnNIETPLKTCCD 210 Borreliella burgdorferi B31
WP_038366914 222 TDIQNDN--SKLIVYIDTRYQ---MLkNQINSIK-DIAHRIKKILK 261 Borrelia duttonii
6ROC_B       164 TNNIQEN--KVLAEHFNKYYKD---------------SDSLQSAFY 192 Borreliella burgdorferi B31
O50891       259 VDNIKID-NKALAKHIKDKYSH------------------PLYLLN 285 Lyme disease spirochete
O50889       249 SDNIKTD-VEALANHMEKKYSH------------------PLYLLD 275 Lyme disease spirochete
ETZ17866     233 KDSIKTTvKNLVEKYLTPKYKD--SLsGLITSSD-QLGKDIKKTLE 275
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