Conserved Protein Domain Family
DUF4939
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pfam16297: DUF4939 
Domain of unknown function (DUF4939)
This family consists of uncharacterized proteins around 110 residues in length and is mainly found in various mammalia species. LDOC1, a member of this family and a novel MZF-1-interacting protein, inhibits NF-kappaB activation and relates with cancer and some other diseases. But the specific function of this family is still unknown.
Links
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Statistics
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PSSM-Id: 465086
Aligned: 3 rows
Threshold Bit Score: 195.135
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_017443841  24 NQLlKQLRILVCERARLlrqvrLPSCPVPYPSRFSGESGRLPEFVVQTMSYMLVNEEHFCNDAMKVAFLISLLSGEAEEW 103
XP_005001429   2 DGR-EQLTKVFMGWPRP-----RWRNPIPFPETFNGDTDRLPEFIVQTGSYMFVDDKTFSSDALKVTFLITRLTGRALEW 75 
Q9D6I0         2 DRR-IKLIMALMAWPELrk--gRWQNPIPFPELFDGEMEKLPEFIVQTLSYMLVDEKTFDTDKRKVMFLITRLKGRALQW 78  house mouse

XP_017443841 104 VMPYIESNSYILGDYRAFVNEMKQYFGWDTDDEDD 138
XP_005001429  76 VMPYIQKDSPLLNNYRAFLAEMKLVFGWEDDEEDF 110
Q9D6I0        79 AMRYLQTDSPMLNNYSGFLNEMKEEFGWE-EDEDF 112 house mouse
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