2OAS,3D3U,3EH7,3QLI


Conserved Protein Domain Family
AcetylCoA_hyd_C
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pfam13336: AcetylCoA_hyd_C 
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Acetyl-CoA hydrolase/transferase C-terminal domain
This family contains several enzymes which take part in pathways involving acetyl-CoA. Acetyl-CoA hydrolase EC:3.1.2.1 catalyzes the formation of acetate from acetyl-CoA, CoA transferase (CAT1) EC:2.8.3.- produces succinyl-CoA, and acetate-CoA transferase EC:2.8.3.8 utilizes acyl-CoA and acetate to form acetyl-CoA.
Links
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Statistics
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PSSM-Id: 433126
Aligned: 160 rows
Threshold Bit Score: 153.363
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2OAS_A        267 GSQKLYDYV-----DDNPAVIFXDIEQVN------D---TSIIR--KNPNVXAINSALQVDLTGQVCADSI-GTKIYSGV 329 Shewanella one...
WP_011995087  328 GSRAFYEKLrampqEMRDKIAMVPVAYVNdlh-gdE---ERKRA--ARQKARFVNTAMMATLTGAVVSDGLeDGRVVSGV 401 Parvibaculum l...
WP_012563792  334 GPKSFYRALremppDRLDRIRMMPVSFTNaly-gdE---DRKRR--GRPKARFVNNAMMVTLLGEAVSDGLsNGQVVSGV 407 Afipia carboxi...
Q3JAD8        444 GPQRFYNFLrglkkEEREQFCMKRVAYVNqly-gsE---ELKRL--QRKDARFLNSALMVTLNGAIISDKLeDGRTVSGV 517 Nitrosococcus ...
WP_012174432  447 GANRFYAYLrrmseEERKQFIMTGVAYVNqly-gdE---TIKRL--QRKDGRFINAGMKVTLMGHVASDALeNGTVISGV 520 Desulfosudis o...
ACL01854      441 GPNGFYDFLrdmsdEERKKFEMTGVKVVN------QlygDEVLRslERKDARFVNAGMKISLMGNVASDALrNGTVISGV 514
CBA16799      366 GSTAFYAWLremdsQTRAGIGMHRISEINqly-gnE---TLRRL--QRRQARFFNSCMMVTALGAAVSDALdDGRVVSGV 439
jgi:Hoch_2646 437 GSRRFFERLralpeAERRRIFMTGVDRVNqlapgrE---ALSRA--QRQRARFVNTCMKMTLTGAAVSDTLsDGQVVSGV 511
Q0VNK9        436 GPRDFYARLlemskQEHAQINMTRISFINhly-gdE---ILKRL--QRQDARFVNTAFTVTLLGAVASDQIeNGRVLSGV 509 Alcanivorax bo...
Q88BB0        361 GPSSFYERLrelpaERLAQFNMTAISYINely-gqE---DLKRL--QRRDARFINSAFTVTLMGAAVADQLeDGRVLSGV 434 Pseudomonas sy...

2OAS_A        330 GGQXDFIRGAGLSEGGRSVIALPSTAA--G-G--R--I-SRIASVLSpgaGVVTTRAHVHYIVTEYGAANLKGRSLRERA 401 Shewanella one...
WP_011995087  402 GGQYNFVAQAFALEDARSVIAVRATRN--KdGk-T--A-SNIVWSYG---HMTIPRHLRDVIVTEYGVADLRGKTDGEVV 472 Parvibaculum l...
WP_012563792  408 GGQYDFVAQAFALEGARSILTLEATRH--N-G--KrlE-SNIRWSYD---HTTIPRHLRDIVVTEYGVAELRGKSDAEVI 478 Afipia carboxi...
Q3JAD8        518 GGQYNFVAMAHALVDARSIIMLRSVRE--KhG--E--IhSNIIWNYG---HTTIPCHLRDMVVTEYGIANLRGKNDREII 588 Nitrosococcus ...
WP_012174432  521 GGQYNFVSMAHALEDARSILMVRSTKDlaH-G--V--D-SNVVFNYG---HTTIPRHLKDIVVTEYGIADLRGKVDSQVV 591 Desulfosudis o...
ACL01854      515 GGQYNFVSMAHALPDARLIMMLRSTKE--TpK--E--VkSNILFNYG---YTTIPRHLRDIVVTEYGIADLRSKQDWVVM 585
CBA16799      440 GGQYNFVAMAHALEDARSVLMFRATRG--N-GgtT--H-SNVRWNYG---HTTIPRHLRDLYVNEYGIADLRGLSDEDCI 510
jgi:Hoch_2646 512 GGQYNFVAMGHALPGGRSVLMLRSTR---G-G-----D-SNIVWEYA---QQTIPRHLRDLVVTEYGIADLRGKTDEECV 578
Q0VNK9        510 GGQYNFVSQAHELEGARSILMVRAWRE--RaG--E--VmSNIVFSYG---HNTIPRHLRDIVITEYGVADLRGKTDEEVV 580 Alcanivorax bo...
Q88BB0        435 GGQYNFVAQAHALEGARSILMLRSWRE--S-Gg-E--VsSNIVWQYG---HTTIPRHLRDIVVTEYGIADLRGQTDATVI 505 Pseudomonas sy...

2OAS_A        402 QALINIAHPDFREQLSRDA 420 Shewanella oneidensis MR-1
WP_011995087  473 AEMLSIADSRFQPELLAQA 491 Parvibaculum lavamentivorans
WP_012563792  479 AAMLCVADSRFQDDLMRQA 497 Afipia carboxidovorans
Q3JAD8        589 IALLNITDSRFQDFLLREA 607 Nitrosococcus oceani ATCC 19707
WP_012174432  592 KCLLNIADSRFQPELLEKA 610 Desulfosudis oleivorans
ACL01854      586 TELIKVADSRFQDELLDEA 604
CBA16799      511 AAMLGIADAQAQPALLAEA 529
jgi:Hoch_2646 579 KALIAISDASVHERLRRVA 597
Q0VNK9        581 MAMLNVADSRFQIELMEQA 599 Alcanivorax borkumensis SK2
Q88BB0        506 ERILNISDSRFQPGLIEQA 524 Pseudomonas syringae pv. tomato
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