Conserved Protein Domain Family
DUF3827

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pfam12877: DUF3827 
Domain of unknown function (DUF3827)
This family contains the Swiss:Q9HCM3 protein which has been found to be fused fused to BRAF gene in many cases of pilocytic astrocytomas. The fusion is due mainly to a tandem duplication of 2 Mb at 7q34. Although nothing is known about the function of Swiss:Q9HCM3 protein, the BRAF protein is a well characterized oncoprotein. It is a serine/threonine protein kinase which is implicated in MAP/ERK signalling, a critical pathway for the regulation of cell division, differentiation and secretion.
Statistics
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PSSM-Id: 463737
Aligned: 12 rows
Threshold Bit Score: 893.758
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_023206243  825 NQTTPDQKYQVHTVLQFIPGHVDMRYCSFFESVEKGLIMAFAEVWRRSKESTN-FTIHILNITTAtnrygekqltRQPVD 903 
XP_012429208  561 WQPLPAYHLQLKTELQFVGQTDNIQSCKFVQTMEQRLQRAFQDAERKVLNTSNnLTVQILNTSNV----------SQAVT 630 
Q6ZVL6        931 WNPQPAGYFQLKTVLQFVSQADNIQSCKFAQTMEQRLQKAFQDAERKVLNTKSnLTIQIVSTSNA----------SQAVT 1000 human
XP_015143070 1010 SFTVPDSRFQVQTVLQFVPRNMDIGFCNFSQRIEKGLTMAFMEVSKQHQEFYN-FTVQILNITLSrpga---afrQGPVS 1085
XP_015208727 1000 VMGVPDHQFQVHSVLQFVPSYIDVRFCNFSERIEKGLIMAFSEVRRRYQESPD-FIVHIINITMNlpkaq-kqlqRVPVD 1077
Q1LY95         65 ISPEPDRQYHVHTVLQFVPSHVDVRMCTFSEQAEKGLIAALAEVRRNSEESTN-FTVNILNITVNqdvdvkaqqqKFPVE 143  zebrafish
XP_011605324  773 NWTTPDRKYHIHTVLQFVPGHIDVRFCNFSESIEKGLTMAFAEVRRRSKESTN-FTVHIVNITMAaqqyyeqqpqRKPVD 851 
2_pfamImport    1 LYSVPELRYQVHTVLQFVPAHVDVRVCNFSERIERGLLLAYGE--RRSQEGRD-VSVQLLNVSALqvaa---arlKLSVD 74  
XP_017210773  546 IYAVPDYKHQVHTVLQFVPGHVDVRLCSFSERVEKGLLMAYAEVRKRSQENGN-FTVHIVNITSSlpkg--qrpqKAPVD 622  zebrafish
XP_014340205  878 AAEVPEYWFQVHTVLQFVPYNVDVRFCNFSQRIERGLSLAFSEVKRRYMEKTS-IIVQLLNITLSvtep--evyrKGPVN 954  coelacanth
XP_027693555 1181 WNPQPAYAFQLKTVLQFVGQSDNIQSCKFVQTMEQRLQKAFQDAEKKVLSTTSnLTVEILNTSNA----------SQAVT 1250 common wombat
XP_005991308 1421 VFPSPAIWFQVKTVLQFVDSTDNIQLCSFVQTMEQGLENAYNDAEVKVLNTKSnLTVEilntskPd--------gSEAVS 1492 coelacanth
XP_023206243  904 ITFTVSGSRGYLMGSKVSNALMKLTMVEFSYYIGFPVLQIAEPFHYPELNTSQLLRSSWVRTVLLGVLDKKM--SERTFQ 981 
XP_012429208  631 LFYVVKNQSTTLNGTVSSNLLNQLSAELVGFYLTYPPLTIAESLEYPNLDVSESTRDYWVITVIQGVDIALLglNNQSFA 710 
Q6ZVL6       1001 LVYVVGNQSTFLNGTVASSLLSQLSAELVGFYLTYPPLTIAEPLEYPNLDISETTRDYWVITVLQGVDNSLVglHNQSFA 1080 human
XP_015143070 1086 IIFAIRDRYGFLNGSEVSEQLRNLSVVEFSFYLGFPVQQIAEPFHYPKLNVSQLMKSSWVRTVLLGVVDQRI--QEEVFQ 1163
XP_015208727 1078 IIFAIRDSTGYLNGSEVSSLLRNLNMVEFSFYLGFPVLQIAEPFHYPELNVTQLLRSSWVKTVLLGVMEQRV--NERTFQ 1155
Q1LY95        144 ITFAVHDMRGYVPGTEVSALLRQLSVVEFSYYLGYPVRQIAEPFHYPELNTTQLLRSSWVRTVLLGVLDQRA--TDKVFH 221  zebrafish
XP_011605324  852 ITFTVRSSRGYLTGSEVSNALMKLTVVEFSYYMGFPVLQIAEPFHYPELNTSQLLRSSWLRTVLLGVMDHKV--GERTFQ 929 
2_pfamImport   75 ITFAVRDGRGYLLGSDVSEHLRKLSLVEFSFYLGFPVLQIAEPLHYPELNTSHHLRSTWVRTVLLEVPEQQV--AERSFR 152 
XP_017210773  623 ITFAVRDSRGFLTGSDVSGHMRQLSAVEFSFYLGFPTLQIAEPFHYPELNVSHLLRASWVKTVLLGVLDQRV--NERTFQ 700  zebrafish
XP_014340205  955 ITFAIRDGDGYLNGSDVSDLFRLLNMVEFSFYLGFPVLHIAEPFHYPELNLSHTLKSSWIKTVLLGVLDYRL--KQKAFQ 1032 coelacanth
XP_027693555 1251 LTYAVWNQSTLLNGTVSSSLLSQLSAELVGFYLTYPPLTIAESLEYPNLDVSETTRDYWVITVLQGVDNTLVglHNQSFA 1330 common wombat
XP_005991308 1493 LIYVVKNHTMMLNGTVSSNLLNRLSAELVGFYLSYPPMIIAEPLEYPSLDTSSATRDYWVITVILGVDNASLgaNYQSFA 1572 coelacanth
XP_023206243  982 ANMERRVALLLGEAMGQV---RRVKRATTVGNSSVQVLSVSRLEGADNPAEMVYFVEgHNGQRMPAVQTANLLNSLDVQR 1058
XP_012429208  711 RLMEQRLAPLFMMSHQQG---RRFRRATTVGSYTVQMVKIQRIPGPKEPAELTYYTL-YNGKPLLGTAAAKILSTVDSQR 786 
Q6ZVL6       1081 RVMEQRLAQLFMMSQQQG---RRFKRATTLGSYTVQMVKMQRVPGPKDPAELTYYTL-YNGKPLLGTAAAKILSTIDSQR 1156 human
XP_015143070 1164 AEMERKLAHLLNEALARG---RIWRRASFAGSNIVQIVNVSRLDGVDNPVELIYFVEdQDGERFSALKCSDLMNRVDIQR 1240
XP_015208727 1156 AKMERRLAQLLGEVLGSA---RRWKRATNVGNNSVQIVRTTRLDGPDNPLEMIYFVEgPNQERLAATTTSSILNQINVQR 1232
Q1LY95        222 ITIERRLALLLGDVLGTG---RRFKRATSVGNNSLQIVQTTHLVGPDNPLEIIYFVEgANGQRLPATTTANMLNSLDVQH 298  zebrafish
XP_011605324  930 ANMERRVAMILGEAMGSA---RRVKRATAIGNSSVQVVSTSRLVGTDHPLEIVYFVEgPDGQRMPADQAAYILNRMDVQR 1006
2_pfamImport  153 ARLERRLALLLQEGLRASs-rRRWRRATAAGNHSLQVARVAMLGGAERPLEVFYFVEgPGGERIPAEAAAAAINGVDPQR 231 
XP_017210773  701 AKMERRLALLVGEGLGIGinnRRWRRSTSVGNNSVQIVRASRLDGPDYPLELVYFVEeGSGERLPAQATAAMLNRLNLQR 780  zebrafish
XP_014340205 1033 AEMERKLAQLISEVQGRV---LRRKRASTLGNSTVQIVTVSRIEGVDDPVELVYFVEgQDGGRLSAVEASHLFNKIDIQR 1109 coelacanth
XP_027693555 1331 RVMEQRLAQLFMMSQQQG---RRLKRATTLGSYTVQMVKMQRVPGPKDPAELTYYTL-HNGKPLLGTAAAKILSTIDSQR 1406 common wombat
XP_005991308 1573 GLMEQRLALLFDSTQQQA---RRFKRANTYNNYIVQMVNMKRVPGQKNPAELTYYAL-HNDEPLLGTTAAKILSTVDPQT 1648 coelacanth
XP_023206243 1059 AAIILGYRVQgVLAQPVekLASSpsdseNSNMWIVIGVVVPLLVVVIIISILYWKLCRTDKLEFQPDAMTTIQQRQKlqa 1138
XP_012429208  787 MALTLGYVIQ-VQADPV--VKNP-----PNNLWIIAAVLAPIAVVTVIIIIITAVLCRKNKNDFKPDTMMNLPQRAK--- 855 
Q6ZVL6       1157 MALTLHHVVL-LQADPV--VKNP-----PNNLWIIAAVLAPIAVVTVIIIIITAVLCRKNKNDFKPDTMINLPQRAK--- 1225 human
XP_015143070 1241 AAIILGYRIDgTVAQPVekLKESsseaqNSNLWIIVGVAVPVAVVLLIVIILYWKLCRTDKLEFQPDTISNIQQRQKlqa 1320
XP_015208727 1233 AAIVLGYRVQgVLAQPVekITAPpsetqNNNLWIVVGVVVPVVVVVIIIIILYWKLCRTDKLEFQPDTMSNVQQRQKlqa 1312
Q1LY95        299 AAIIMGYRIQgILAQPVekQASPpsdteKTNTWIIIGVVVPVLLVVIIISILYWKLCRTDKLEFQPDTVSTVQQRQKlqa 378  zebrafish
XP_011605324 1007 AAIILGYRVQgVLAQPVekVASApsdteNTNLWIVVGVVIPLLVVIIIISILYWKLCRTDKLEFQPDAMTSIQQRQKlqa 1086
2_pfamImport  232 AAIILGHRVRkPVAQPAetAPVPpaethSSSIWLIVGVIVPILLALFIVVILYWKLCGSEKLEFQPDAVNAVQQRQKlqa 311 
XP_017210773  781 AAIVLGYRVHgVLATPVekLALPpsetqPSNVWLIVGVVVPVLVVVLIIIILYWKLCRSEKLEFQPDAMSTIQQRQKlqp 860  zebrafish
XP_014340205 1110 AAIILGYRVRgTVAQPVekVEQPps-dtKNNLWIILGVAGPVIVVVIIIVILYWKLCRTDKLEFQPDTMSNIQQRQKlqa 1188 coelacanth
XP_027693555 1407 MALTLHHVVL-LQADPV--VKNP-----PNNLWIIAAVLAPIAVVTVIIIIITAVLCRKNKNDFKPDTMVNLPQRAK--- 1475 common wombat
XP_005991308 1649 MALTLGYIVQ-LQAEPI--VKNP-----PNNLWIIAAVLAPIAVVTVIIIIITAVLCRKSKHDFKPDSMGNMHQRTK--- 1717 coelacanth
XP_023206243 1139 pSVKGFDFAKLHLGQQSKDD--VMVIQEPAlpgsgsaPLAQSIKDgFSPSENGEVPTPKSKTsasstKASR-GGRRReRI 1215
XP_012429208  856 -PVQGFDYAKQHLGQQGAEDevLPVTQETV-------ILPLPVRD-APASQERETTQDGSTI-----KTAKsNETRK-SR 920 
Q6ZVL6       1226 -PVQGFDYAKQHLGQQGADEevIPVTQETV-------VLPLPIRD-AP--QERDVAQDGSTI-----KTAKsTETRK-SR 1288 human
XP_015143070 1321 pSVKGFDFAKQHLGQHNKDD--VLIIHEPA-------PLPGPIKD-TTPSENGDVPSPKSKTs---sKPSK-TVRHRgRV 1386
XP_015208727 1313 pSVKGFDFAKLHLGQHNKDD--ILVIQESA-------PLPAPVKE-VTPSESGDVPSPKSKAs---sKVSR-GAKRRgRI 1378
Q1LY95        379 pSVKGFDFAKLHMGQHSKDD--LMVIQDPL-------PLPVPAKE-QSPAENAEVPTPKSKSs---sKASRsGQRRRgQI 445  zebrafish
XP_011605324 1087 pTVKGFDFAKLHLGQHSKDD--VMVIQEAAppgtgsgPLPMPAKDgLSRSDNGELPAPISKNs---tKASR-SSKRHeRI 1160
2_pfamImport  312 pSVKGFDFAKLHLGQHSKDD--MLVIQEPG-------PLPAPAKE-ATPSDAGDLNTPKSKSss--nKGAR-SGRRRgRL 378 
XP_017210773  861 pSVKGFDFAKLHLGQHSKDD--IMVIQEPA-------PLPPSVKE-ATPSEGGELNTPKSKSss--tKASR-AARRRgRL 927  zebrafish
XP_014340205 1189 sSVKGFDFAKQHLGQHNKED--VLVIQEPS-------PQPLPVKD-ATPSENGNVPTPKPKTt---pKTSK-GIRHRgRI 1254 coelacanth
XP_027693555 1476 -PVQGFDYAKQHLGQQGAEEevIPVTQETV-------VLPLPVRD-APASQEREIAQDGSTI-----KTAQsTETRK-SR 1540 common wombat
XP_005991308 1718 -PVQGFDYAKQHLGQQGADEevVPVTQETV-------VLPLPVRD-APLSHEREIPKDGSTT-----KTAKsLEARK-SR 1782 coelacanth
XP_023206243 1216 SPSDGDSVVSDHSSEREPTEENP-RAHATPSDSK-QTRKNRIgppp----mngaANEQLSSASIFEhvdRMSR-ATDASR 1288
XP_012429208  921 SPSQAGSILSNGSGKPSSGRSSLqKVMAPQKAAKeEGRKRNVa-----------VSDEEEGGILFD---NVAKsAVDPFD 986 
Q6ZVL6       1289 SPSENGSVISNESGKPSSGRRSPqNVMAQQKVTKeEARKRNVp-----------ASDEEEGAVLFD---NSSKvAAEPFD 1354 human
XP_015143070 1387 SPSDADSTASEQSSGRETGEETA-RPSAVANEGK-PRRATKKgppq-----sssGNEQHSSASIFEhvdRMSR-SSDASR 1458
XP_015208727 1379 SPSDAESTVSEPSSGRESAEEST-RPSITPIDGK-QHRKTVRngpp----qmngTEEPLSSASIFEhvdRMSR-TSEATK 1451
Q1LY95        446 SPSEGDSIGSDPASERGSPEEGT-RPAGLPSDPK-QTRKSAAnglngp-ppmngMDEPLSSASIFEhvdRMSR-PVDGPK 521  zebrafish
XP_011605324 1161 SPSDGDSVVSDHSSEREPNEENR-RGYTTPSDGK-HTRKVPInvlngp-ppmngTNEQLSSASIFEhvdRLSR-GADASR 1236
2_pfamImport  379 SPSDGDSLGSDQSSARESAEESA-RAVATPTEGK-QHRRTPRngqkn---lpstPDEFLSSTSIFDhvdRLSRgSADGLR 453 
XP_017210773  928 SPSDGDSLGSEASSGRESAEEST-RPAVTPSDSKpQHRKSKhaknklgaqpgsgVDEQLSSSSIFEhvdRVSRgSSDGTR 1006 zebrafish
XP_014340205 1255 SPSDAESLGSEPSSGRESAEEEP-RPALAPSEGK--HRKEMKngpp----vsngTDEQHSSASIFEhvdRNSR-SSAASR 1326 coelacanth
XP_027693555 1541 SPSENGSVLSSESGKPSPGRPSS-QNVTATATAQ-QQKVTKEegrk----rnvpVSDEEEGAGLFD---STGKpVADPFD 1611 common wombat
XP_005991308 1783 LPSENGSVFSNESGKPNSGGSSMqKITAQQKNTKeETRKKNAp-----------LSDEEEGAVLFDh---DSKnSLDPFD 1848 coelacanth
XP_023206243 1289 RLPNKVQLIAMQPM----PVPPLh------sQPVNGKPSD-PNQMNKEIQAALRHKSEIEHHRNKIRLRAKRKGHYDFPA 1357
XP_012429208  987 TSSGSVQLIAIKPV----ALPAV--------HAASERSQE-SAIINGEVNKALKQKSDIEHYRNKLRLKAKRKGYYDFPQ 1053
Q6ZVL6       1355 TSSGSVQLIAIKPT----ALPMV--------PPTSDRSQEsSAVLNGEVNKALKQKSDIEHYRNKLRLKAKRKGYYDFPA 1422 human
XP_015143070 1459 RVPSKIQLIAMQPM----AAPPVq------nSVLSDRVAE-TNKINKEIQTALRHKSEIEHHRNKIRLRAKRKGHYEFPV 1527
XP_015208727 1452 RVSNKIQLIAMQPM----PASPLh------sTAVLEKVSE-TAKINKEIQTALRHKSEIEHHRNKIRLRAKRKGHYDFPA 1520
Q1LY95        522 RLPNKIQLIAMQPM----PALPLp------nTTANDKAAE-NAKLNKEIQVALRHKSEIEHHRNKIRLRAKRKGHYDFPA 590  zebrafish
XP_011605324 1237 RLPSKVQLIAMQPM----PLPPLh------gTPINDKLSD-ANQITREIQVALRHKSEIEHHRNKIRLRAKRKGHYDFPA 1305
2_pfamImport  454 RQGNKVQLIAMQPQ----PSPPHaas--qpsPSLTEK-------------VALRHKSEIEHHRNKLRQRAKRRGQCEFPS 514 
XP_017210773 1007 RVSNKIQLIAMQPM----PSPPShphnqplsPNLTDKITD-GAKVNSEIQVALRHKSEIEHHRNKIRLRAKRKGHYEFPS 1081 zebrafish
XP_014340205 1327 RVPNKIQLIAMQPI----VAPPLq------kPLVLERVAE-SCKINKEIQTALRHKSEIEHHRNKIRLRAKRKGHYEFPV 1395 coelacanth
XP_027693555 1612 TSSGSVQLIAIKPAvlapAHPAS------------ERSQE-SAIINGEVNKALKQKSDIEHYRNKLRLKAKRKGYYDFPQ 1678 common wombat
XP_005991308 1849 TSSGSVQLISIKPL----TAPPSy------sHPASDRSQE-SAVINGEVNKALKQKSDIEHYRNKLRLKAKRKGYYDFPQ 1917 coelacanth
XP_023206243 1358 MDDMvGSLSDTke----qDRIYQKAQTQIDKILDPDN-PVP-AVFMDSKKSGr--GRRSPKQRLKDQ-LNGGLIEADKDH 1428
XP_012429208 1054 VDNS-KALTDR-------KRMYEKNQKELDHILDPDA-DVS-SPFAEPKNRQ---PLKNSVYRSRQSlNSPSPGETEMDL 1120
Q6ZVL6       1423 VETS-KGLTER-------KKMYEKAPKEMEHVLDPDS-ELC-APFTESKNRQ---QMKNSVYRSRQSlNSPSPGETEMDL 1489 human
XP_015143070 1528 VDDV--VVVDSke----qHRIYRKAQMQIDKILDPGG-SVP-TVFIEPRKSSr--AKRSPKQRRRHQ-INGSPVDAEKDR 1596
XP_015208727 1521 MDDI--GIVDSre----hRRIYQKAQMQIDRILDPEV-HVP-SVFIESKKSAr--GKRSPKQRRKHQ-VNGSLTDADKDR 1589
Q1LY95        591 MDDLiDGLGDPke----qDRIYQKAQMQIDKILDPDI-HMP-SLYTEPKKSNr--GKRSPKQRRKQQ-MNGELTDADRDR 661  zebrafish
XP_011605324 1306 MDDLtCGLGNGkd----qDQIYQKAPTQ---IVDPEA-QMPmSIFTGSKKSGr--ARRSPKQRVKEQ-LNGGAREADKDH 1374
2_pfamImport  515 MDDImDAFGDGpvqgeaaQRLYSSAHDHMDCMVPSDG-PSP----TDSRRRSpcrGRSSPRGRRAQP-GLGSLPDTDRDR 588 
XP_017210773 1082 MEDImAAFGDNse----qQRVYQQAQEQIHKILHPDE-HTH-SSCGEPRKSSr--GRRSPRHRQRQQnLSGSGSPRDKDR 1153 zebrafish
XP_014340205 1396 MEDV--AFTDTkd----rRRLYRKAQMQIDRILDPNAhHAP-SISMEPRKSSr--AKRSPRQRRRHQ-MNGSLTDIEKDR 1465 coelacanth
XP_027693555 1679 VEGN-KALTE--------RKMYEKAPKDIDHVLDTEP-EVP-SPFGEPKSRQ---QMKNSVYRSRQSlNSPSPGETEMDL 1744 common wombat
XP_005991308 1918 VDSNsKSLTDRq------RKMYEEAQKEIDKVLEPET-DGS-SPFTRPKNRQs--RMKNTVYKSRQSlNSPSPGGTEMDF 1987 coelacanth
XP_023206243 1429 ---LITEDsdavyRKCPGVNNVAYVSDPDQGPGSpqRSPSPTD-DVFLGPASSPPGHapPPPPYLPPQPSIEEARQQMHS 1504
XP_012429208 1121 ---LVTRE-----RPRRGIRNSGYDTEPEIIEET--NIDRVNE-PRNYGRARQAKGH--SETSTLSSQPSIDEVRQQMHM 1187
Q6ZVL6       1490 ---LVTRE-----RPRRGIRNSGYdTEPEIIEET--NIDRVPE-PRGYSRSRQVKGH--SETSTLSSQPSIDEVRQQMHM 1556 human
XP_015143070 1597 ---LITTDsdgtyKRPPGVNNSAYISDPDLPPEP--QTSSSAD------LGKFPGLPshPVSQYVPPQPSIEEARQTMHS 1665
XP_015208727 1590 ---LITTDsdgtyKKPPGVNNVAYVSDPDQAPEP--RSPSPQDnEVF--VGSPPPGHapPPPAYVPPQPSIEEARQQMHS 1662
Q1LY95        662 ---LITTDsdgtyRKYPGVNNIAYVSDPDQCPEH--NSPSPTD-DVFHCPISPPPGHppPPPPYLPPQPSIEEARQQMHS 735  zebrafish
XP_011605324 1375 ---LISEDsegiyRRCPGVNNVAYVSDPDQGQCSphRSPSPTD-DVFLGPTCSPPGHapPPPPYMPPQPSIEEARQQMHS 1450
2_pfamImport  589 drdRLLAEqsatyRKYPGLNNVAYMSDPDLPPDR--SSPSPSD-ESL--------TPrpPRRPTRPPGPPSRRRGSSMHS 657 
XP_017210773 1154 ---LI-SDrdatyRKYPGVNNVAYVSDADQLPDA--GSPSPTD-EVFLDPGSPPSGPapSPPAYVPPQPTIEEARQQMHS 1226 zebrafish
XP_014340205 1466 ---LIATDsdgtyKRPPGFNNVAYISDPDVPIVS--QTPSPQDgEVF--PGSPPHGHppPPPPYIPPQPSIEQARQQMHS 1538 coelacanth
XP_027693555 1745 ---LVTRE-----RPRRGIRNSGYDTEPEIIEET--NIDRVNE-PRGYPRSRQVKGH--SETSTLSSQPSIDEVRQQMHM 1811 common wombat
XP_005991308 1988 ---LVTRE-----RPRRGIRNSGYdTEPELIEET--NIDRVAE-SRSYGRSRQGKGH--SETSTLSSQPSIDEVRQQMHL 2054 coelacanth
XP_023206243 1505 LLDDAFALVSPTS 1517
XP_012429208 1188 LLEEAFSLASAGH 1200
Q6ZVL6       1557 LLEEAFSLASAGH 1569 human
XP_015143070 1666 LLDDAFALVAPSS 1678
XP_015208727 1663 LLDDAFALVAPTS 1675
Q1LY95        736 LLDDAFALVSPSS 748  zebrafish
XP_011605324 1451 LLDDAFALVSPTS 1463
2_pfamImport  658 LLDDAFALVSPSS 670 
XP_017210773 1227 LLDDAFALVSPSS 1239 zebrafish
XP_014340205 1539 LLDDAFALVAPGS 1551 coelacanth
XP_027693555 1812 LLEEAFSLASAGH 1824 common wombat
XP_005991308 2055 LLEEAFSLASAGR 2067 coelacanth
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