1EC7


Conserved Protein Domain Family
glucar-dehydr

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TIGR03247: glucar-dehydr 
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glucarate dehydratase
Glucarate dehydratase converts D-glucarate (and L-idarate, a stereoisomer) to 5-dehydro-4-deoxyglucarate which is subsequently acted on by GarL, tartronate semialdehyde reductase and glycerate kinase (GenProp0716). The E. coli enzyme has been well-characterized.
Statistics
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PSSM-Id: 211799
Aligned: 8 rows
Threshold Bit Score: 871.434
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1EC7_A         5 FTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIKDNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLGEYKNVL 84  Escherichia col...
WP_000098276   5 FTTSVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIKDNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLGEYKNVL 84  Shigella sonnei
WP_011088613  12 AGAPVVTAMQVIPVAGRDSMLLNLSGAHAPFFTRNIVILTDNAGHTGVGEVPGGQKIWQTLQDARDLVIGKTVGAMNNIL 91  Bradyrhizobium ...
WP_011038345  11 SATPRITDVRVVPVAGQDSMLLNLSGAHAPYFTRNVLVLHDSSGRIGVGEVPGGEAIAALLREAAGLILDRPIADYQRIL 90  Xanthomonas cam...
WP_011401690  17 TTTPVVSDLRVVPVAGRDSMLLNLSGAHGPFFTRNIVLIRDSAGNTGVGEVPGGEGIRRTLEDARALVVGQPLGRWQDVL 96  Burkholderia th...
WP_011210040   5 ARTPRVTEMRVVPIAGHDSMLLNLSGAHAPYFTRNLVILTDSAGRTGVGEVPGGERIRATLEEARGLVIGRGLGEHHAVL 84  Nocardia farcinica
BAA06470      15 SNIPSISEMKVIPVAGHDSMLLNLSGAHSPFFTRNIVILTDSSGNQGVGEVPGGEHIRRTLELSEPLVVGKSIGAYQAIL 94  Bacillus subtilis
WP_004930680   3 ASTPIIQSVRAIPVAGHDSMLLNLSGAHAPYFTRNLLVIEDNSGNIGVGEIPGGEKILATLNDAKSLILGQPIGEYKNLL 82  Acinetobacter
1EC7_A        85 TLVRNTFADRDAGGRGLQTFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGNRKATPLPY 164 Escherichia col...
WP_000098276  85 TLVRNTFADRDAGGRGLQTFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGNRKATPLPY 164 Shigella sonnei
WP_011088613  92 ADVRTAFADRDAGGRGKQTFDLRVMIHAVTAIESALLDLLGQHLNLPVAALLGEGQQRKSVETLGYLFFVGDISKSRLDY 171 Bradyrhizobium ...
WP_011038345  91 NQVRATFADRDSAGRGLQTFDLRITIHAVTAIESALLDLLGQFLEQPVAALLGEGQQRDAVDVLGYLFFIGDRRKASVAY 170 Xanthomonas cam...
WP_011401690  97 NAVRARFADRDAGGRGLQTFDLRITIHAVTALEAALLDLLGQHLGVPVAALLGEGQQRSRVPMLGYLFYIGDRKRTDLDY 176 Burkholderia th...
WP_011210040  85 GDIRRTFAARDAAGRGNQTFDLRVTVHAVTAVESALLDLLGQHLEVPVAALLGDGVQRTDVPALGYLFFVGDRNRTDLPY 164 Nocardia farcinica
BAA06470      95 QTVRKQFGDQDRGGRGNQTFDLRTTVHAVTALEAALLDFLGKFLQEPVAALLGEGKQRDEVKMLGYLFYIGDRNRTTLPY 174 Bacillus subtilis
WP_004930680  83 KKIHQTFADRDSGGRGNQTFDLRTTVHVVTAYESALLDLLGKHLNVNVASLLGDGQQRDEVEVLGYLFFIGDRKQTSLDY 162 Acinetobacter
1EC7_A       165 Q---SQPDDSCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAESIVALAQRFPQARITLDPNGAWS 241 Escherichia col...
WP_000098276 165 Q---SQPDDSCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAESIVALAQRFPQARITLDPNGAWS 241 Shigella sonnei
WP_011088613 172 V---TGETGKAEWFNLRHQEAMTPETVVRLAEATHDHYGFADFKLKGGVLRGEQEIEAVTAIAKRFPNARVTLDPNGAWS 248 Bradyrhizobium ...
WP_011038345 171 R---DGSGARDRWESLRDEEALTPDAVVALAEAAYDKYGFRDFKLKGGVLRGEQEIEAIRALHARFPQARITLDPNGAWS 247 Xanthomonas cam...
WP_011401690 177 R---SEPQADDAWFRLRNEVALTPDAIVRLAEAAHARYGFQDFKLKGGVLSGDDEIAAVTALAKRFPNARITLDPNGAWS 253 Burkholderia th...
WP_011210040 165 RspaDEPADADDWLRRRHEEAMTPEGVVELARAARARYGFRDFKLKGGVLAGAEEAAAVRALAEEFPDARITLDPNGGWL 244 Nocardia farcinica
BAA06470     175 Q---SDEQSDCAWFRLRHEEALTPEAIVRLAESAQERYGFQDFKLKGGVLRGEEEIEAVTALSKRFPEARITLDPNGAWS 251 Bacillus subtilis
WP_004930680 163 A---TSTHLNHDWYQVRHEKALTPEAIQRLAEASYDRYGFKDFKLKGGVLHGEQEAEAVTAIARRFPDARVTLDPNGAWY 239 Acinetobacter
1EC7_A       242 LNEAIKIGKYLKGSLAYAEDPCGAEQGFSGREVMAEFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQG 321 Escherichia col...
WP_000098276 242 LNEAIKIGKYLKGSLAYAEDPYGAEQGFSGREVMAEFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQG 321 Shigella sonnei
WP_011088613 249 LDEAVSLCKDMHGILAYAEDPCGAEAGFSGREIMAEFRRATGLPTATNMIATDWRQLSHALRLGAVDIPLADPHFWTMQG 328 Bradyrhizobium ...
WP_011038345 248 LEQAIALCRDLHGVLAYAEDPCGAQDGYSGREVMAEFRRATGLPTATNMIATDWRQMGHAIQLQSVDIPLADPHFWTLQG 327 Xanthomonas cam...
WP_011401690 254 LQEAIRLCRGKGDVLAYAEDPCGAENGYSGREIMAEFRRATGLPTATNMIATDWRQLGHALRLGSVDIPLADPHFWTMRG 333 Burkholderia th...
WP_011210040 245 LREAVPLCRDLRDVLAYAEDPVGPEGSFSGREVMAEFKRATGLPTATNMIATDWRELGHTVRTDAVDIPLADPHFWTMAG 324 Nocardia farcinica
BAA06470     252 LEEAIALCKGKQDVLAYAEDPCGDENGYSAREVMAEFRRATGLPTATNMIATDWREMGHAIQLHAVDIPLADPHFWTMQG 331 Bacillus subtilis
WP_004930680 240 LDEAIGLGKHLKGVLAYAEDPCGAEQGYSSREIMAEFKRATGLPTATNMIATDWREMSHSIQLQAVDIPLADPHFWTLEG 319 Acinetobacter
1EC7_A       322 SVRVAQMCHEFGLTWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGnQRLTKEPFEIKGGLVQVPEKPGLGVE 401 Escherichia col...
WP_000098276 322 SVRVAQMCHEFGLTWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGnQRLTKEPFEIKGGLVQVPEKPGLGVE 401 Shigella sonnei
WP_011088613 329 SVRVAQTCRDNGLTWGSHSNNHFDISLAMFTHVGAAAPGKVTAIDTHWIWQDG-QALTREPLRIKGGKIAVPDRPGLGIE 407 Bradyrhizobium ...
WP_011038345 328 SVRVAQMCRDWGLTWGSHSNNHFDISLAMFTHVAAAAPGRVTAIDTHWIWQDG-QRLTHAPLTIAGGQIQVPAKPGLGIE 406 Xanthomonas cam...
WP_011401690 334 SVRVAQLCDEWGLTWGSHSNNHFDISLAMFTHVAAAAPGNITAIDTHWIWQDG-QRLTREPLRIEDGHVAVPQRGGLGVE 412 Burkholderia th...
WP_011210040 325 SVRVAQLCDAWGLTWGSHSNNHFDVSLAMFTHVAAAAPGEITAIDTHWIWQDG-QRITREPFRIVEGRITVPRRPGLGVE 403 Nocardia farcinica
BAA06470     332 SVRVAQMCHDWGLTWGSHSNNHFDISLAMFTHVAAAAPGRITAIDTHWIWQDG-QRLTKQPFEISSGCVKVPDKPGLGVD 410 Bacillus subtilis
WP_004930680 320 SVRVSQLCNMYNLTWGSHSNNHFDVSLAMFTHVAAAAVGNVTAIDTHWIWQEGtDHLTKQPLEIKGGKIQVPSVPGLGVE 399 Acinetobacter
1EC7_A       402 IDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR 446 Escherichia coli K-12
WP_000098276 402 IDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR 446 Shigella sonnei
WP_011088613 408 IDRAAIDAAHDLYKQHGLGARDDAIAMQDLIPGWTFDDKRPCLVR 452 Bradyrhizobium diazoefficiens
WP_011038345 407 LDIDALDAAHRTYQSLSLGARDDAAGMQCLIPNWAFDNKRPCLVR 451 Xanthomonas campestris
WP_011401690 413 IDEDALAGAHELYLEHGLGSRDDAVAMRYLVPDWTFDNKRPCLVR 457 Burkholderia thailandensis
WP_011210040 404 LDEERVAAAHELYLRAGLGDRNDATTMQYLIPGWQFDSKRPALVR 448 Nocardia farcinica
BAA06470     411 IDMEQVEKAHEIYRKMNLGARNDAIPMQFLISNWEFDRKRPCLVR 455 Bacillus subtilis
WP_004930680 400 LDWDNINRAHELYKAKGLGARNDADAMQFMVPNWKFDHKKPCLVR 444 Acinetobacter
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