1YAC


Conserved Protein Domain Family
YcaC_related

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cd01012: YcaC_related 
Click on image for an interactive view with Cn3D
YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. Multimerisation interface seems not to be conserved in all members.
Statistics
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PSSM-Id: 238494
Aligned: 29 rows
Threshold Bit Score: 173.164
Created: 6-Mar-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
Conserved site includes 3 residues -Click on image for an interactive view with Cn3D
Feature 1:catalytic triad [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1            #                                                                  #       
1YAC_A       14 AVLLVDHQAGLLSlvrdi-epdkfKNNVLALGDLAKYFnlPTILTTSaet-gpNGPLVPELkaqfPDAPYIARPgnINAW 91  Escherichia coli
NP_770892    55 ALLLIDQQAGLAFgvgsi-drqalLNNTIALARTAKVFglPIVASTSask-vySGPLMAAIrevlPDIHPIERRn-MNLW 131 Bradyrhizobium j...
NP_832865    14 VVLLVDHQTGLMSglvrdygvdefKNNVLALAHTAKFFdlPVILTTSfen-gpNGPLMQELvdlfPHAPKIARPgqINAW 92  Bacillus cereus ...
NP_436249    38 ALIMIDFQSQMSFatksi-davqlRNNAALVASAAAGFgvPTILTTVaek-sfSGPMFAEItdafPEQPLLDRTs-MNTW 114 Sinorhizobium me...
XP_306124    17 ALILIDYQPLQVNsiksm-dheelVKNIVTVSKLARGFniPVVLSTVnvesgiNKPTIKQLkdvlSDVDEIDRTt-VNSW 94  Anopheles gambia...
NP_631764    19 VLALIDHQPFQVAnlhsh-eptmvINNAVGLAKAAKVFevPTILTTVle--erGGLILPGLqevfPEQKPINRTf-INTW 94  Streptomyces coe...
NP_770897    18 AIALIDYQPAMFQgvqsh-drlvtINNVQILAKAAKLFkiPTVLTTVard-sfSGPFIPEVtslfPKHDVIDRTs-MNSW 94  Bradyrhizobium j...
NP_518363    15 QLIFIDHQPQMAFgvqsi-drqvlKNNTVGLAKAARIFdiPTTITTVete-gfSGYTYPELldvfPGKELLERTs-MNSW 91  Ralstonia solana...
NP_459926    20 VMLLIDHQSGLFQtvgdm-pmpelRARAAALAKMATLAkmPVITTASvpq-gpNGPLIPEIhanaPHAQYIARKgeINAW 97  Salmonella typhi...
ZP_00031917  12 AVALIDYQPQMFFgtmsh-ertniLHNVQAIAKAAKLFkvPTILTTVaak-sfSGDMVPEVqsvfPEYVPVDRTs-MNSW 88  Burkholderia fun...
Feature 1                                 #                                                     
1YAC_A       92 dnedFVKAVKatgkKQLIIAGVVTEVCVAFPALSAIEE-GFDVFVVTDASGTFNeitRHSAWDRMSQAGAQLMTwFGVAC 170 Escherichia coli
NP_770892   132 eddaARTAVLqtgkRRLIVSGLLTEACVSFLVLSALQE-GFDVFVVGDACGGLTpvsHDLALRRMSDAGAHMTSwIQVLL 210 Bradyrhizobium j...
NP_832865    93 dnddFVKAIEetgkKQLIIAGVVTDVCVAFPALSAIKA-GYEVFAVTDASGTFSkqvADAANTRMAHSGVQLMNwFSVAC 171 Bacillus cereus ...
NP_436249   115 edaaVIEEVNrigkKRLVFCGLWTSVCIVGPTLSALDQ-GFEAYVIADACGDVSdeaHERAMDRMVQAGVRPMTsLQYML 193 Sinorhizobium me...
XP_306124    95 edqeFQDALKklgkKKLIVCALWTEVCLCFPALDLIKE-GYEVYTIVDAVGGTSkiaHETALRRMEQAGVQLSSvTQFAC 173 Anopheles gambia...
NP_631764    95 qderVVDAVKatgrKKLIIAGLWTEICVAMPAIQAVGE-GFEVFVVTDASGGVSreaHDMAVQRMIQAGVVPITwMAVLG 173 Streptomyces coe...
NP_770897    95 ldanFRKAVAatgrKKFVLAGLWTEACVIFPTLDMLKE-GYEIYIAADACGDLSleaHNRAVERAIQAGAVPITsSQYAY 173 Bradyrhizobium j...
NP_518363    92 ddqkVRDVLArngrKKVVVSGLWTEVCNTTFALCAMAEgGYEIYMVADASGGTSkeaHDYAMQRLIQAGAVPVTwQQVLL 171 Ralstonia solana...
NP_459926    98 dnedFVKAVKatgrKTLIIAGTITSVCMAFPAISAVAE-GYKVFAVIDASGTYSkmaQEITLARIVQAGVVPMDtAAVAS 176 Salmonella typhi...
ZP_00031917  89 edvnFRKAIEatgrKKIVISGLWTEVCVSFPTIQMIAE-GYEIYVPTDACGDVSqeaHERAVQRIIQAGAVPMTsLQFMF 167 Burkholderia fun...
Feature 1           
1YAC_A      171 ELHR 174 Escherichia coli
NP_770892   211 EFQR 214 Bradyrhizobium japonicum USDA 110
NP_832865   172 ELQR 175 Bacillus cereus ATCC 14579
NP_436249   194 ELQR 197 Sinorhizobium meliloti
XP_306124   174 ELQR 177 Anopheles gambiae str. PEST
NP_631764   174 EWQR 177 Streptomyces coelicolor A3(2)
NP_770897   174 ELQQ 177 Bradyrhizobium japonicum USDA 110
NP_518363   172 EWQR 175 Ralstonia solanacearum
NP_459926   177 ELQG 180 Salmonella typhimurium LT2
ZP_00031917 168 ELQR 171 Burkholderia fungorum

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