Conserved Protein Domain Family
SAM_Samd14
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cd09530: SAM_Samd14 
SAM domain of Samd14 subfamily
SAM (sterile alpha motif) domain of SamD14 (or FAM15A) subfamily is a putative protein-protein interaction domain. SAM is widespread domain in proteins involved in signal transduction and regulation. In many cases SAM mediates homodimerization/oligomerization. The exact function of proteins belonging to this subfamily is unknown.
Links
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Statistics
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PSSM-Id: 188929
Aligned: 10 rows
Threshold Bit Score: 115.88
Created: 11-Mar-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9P1V8       543 LNWDPEEVAEWISQLG-FPqYKECFITNFISGRKLIHVNCSNLPQMGITNFEDMKAISRHTQELLEIE 609 human
XP_002589245   7 LHWSCDDVADWIEQLG-FPqYRECFTTNLINGRKLIQVDCSSLPRLGITDFEHMKLIARSVRELLGIE 73  Florida lancelet
XP_421290     14 LAWGTAEVAEWVSGLG-FPqYQECFRANGITGRRLILVNCSSLPAMGITDFKHMQEISRHVRELLGIE 80  chicken
XP_002115198  14 INWQAEAVADFIENIG-FKqYRKTFLQNEIKGRNLIAVDASTLPKMGITDFDHIKIITKNIRELLKIE 80  Trichoplax adhaerens
XP_002120831  16 IHWTCDDVANWIEEIG-FPqYRLCFTNNLIDGRKLVLMDASNLPKLGVTDFDHILFIASSVRDLLNIE 82  Ciona intestinalis
XP_001629416  12 IKWTIEDVAEWIEYLG-FKqYRRPFSDNLVNGRRLIQVDASTLPRMGVTDFEHIKFISKKIREALGIE 78  starlet sea anemone
CAX73255      16 LLWDVGQVACWIEDIG-YPqYKECFTGNQIDGRSLIKIHSSTLPDIGVTKFEDIKNIVCKVRELLNLD 82  Schistosoma japonicum
XP_002164403  19 LSWSVADVGLWVRGVLqYPeYEECFVKNFINGQKLIYIDASILPRIGVTNFLHIMDIASKVRVLLGIE 86  green hydra
XP_001742369  40 FSWTTTQVANFITEAG-FErYAACFTENFVDGQKLQYIDATQLNRLGVRDFEDIKAVAAIIRQQFQHP 106 Monosiga brevicollis MX1
AAF50964      77 FEWDDMDIRRWINGYG-YPqYMNTFRVNMITGRKLLLLDASALCAMNIKNFDHIRHISYGIRMLFHFE 143 fruit fly
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