1URP,2DRI,1URP,2IOY,1DBP,2GX6,1BA2,1DRJ,1DRK,4ZJP


Conserved Protein Domain Family
PBP1_ribose_binding
?
cd06323: PBP1_ribose_binding 
Click on image for an interactive view with Cn3D
periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs
Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis D-ribose binding protein (ttRBP) and its mesophilic homologs. Members of this group belong to the type 1 periplasmic binding protein superfamily, whose members are involved in chemotaxis, ATP-binding cassette transport, and intercellular communication in central nervous system. The thermophilic and mesophilic ribose-binding proteins are structurally very similar, but differ substantially in thermal stability.
Links
?
Statistics
?
PSSM-Id: 380546
Aligned: 25 rows
Threshold Bit Score: 343.894
Created: 2-May-2008
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
 
ligand binding
Conserved site includes 12 residues -Click on image for an interactive view with Cn3D
Feature 1:ligand binding site [chemical binding site]
Evidence:
  • Structure:2DRI; Escherichia coli periplasmic binding protein binds ribose, contacts at 3.5A
  • Citation:PMID 7982928
  • Structure:2IOY; Thermoanaerobacter tengcongensis periplasmic binding protein binds ribose, contacts at 3.5A
Download Cn3D for Viewing 3D StructureScroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1               # ##                                                    #             
1URP_D      3 TIALVVSTLNNPFFVSLKDGAQKEADKl-----GYNLVVLDsqnnpAKELANVQDLTVrGTKILLINPtdsDAVGNAVKM 77  Escherichia coli K-12
2DRI_A      3 TIALVVSTLNNPFFVSLKDGAQKEADKl-----GYNLVVLDsqnnpAKELANVQDLTVrGTKILLINPtdsDAVGNAVKM 77  Escherichia coli
KHG65698   26 VVGLSLSTLNNPFFVALRDGALQAAQKa-----GIQLVVLDaqdrvDKQVADIEDLIQrRVRVLLVNPtdsAAVVPAIQR 100 Thermus sp. 2.9
APZ41703   34 TFALLLSTLNNPYFVTMKNSAQAEAKRl-----GVKLLVLDgnnssTTQSNQVRTAIArKVNLLLINPtnaTAMSPAVKE 108 Acidihalobacter fe...
CUH95937   43 VIGFSVSTLNNPFFVDLRDGAQAAAKEm-----GVELIVMDaqndtSKQMSNIENLVQqKVSVLIVNPvdsKAIVPAIEA 117 Propionispora sp. ...
NP_600477  39 SITLALSTQTNPFFVQLRDGAQEKADEl-----GVTLNVQDasddaATQANQLNNAVTtGAGVVIVNPtdsDAVVPSVEA 113 Corynebacterium gl...
CRH66959   37 KVALLVSTLNNPFFVDLRDGAQAEAKKl-----GVDLQVSDaqndsSKQQDQAQNAQSqGAKAVIINPvdsDAAGPAVAP 111 Chlamydia trachomatis
AFK51429   39 KVGLFISNLGNPYFALLRDGAQAAVNElknkgvSIEMVVYDakddpSLQSNQIETAVGqKFSALVVNPtdiQAIQPSLSK 118 Thermogladius cell...
OQX07684  310 KIGLSVSNLANPFFDLLRKGAQDTGELf-----GFKVTVADaknddAKQLLDIQKFIKdKADVIIINPtnvETVSPGIEM 384 Desulfobacteraceae...
EPD68668   35 TVTLALSTEKNPFFLQVRYGAQAKANEl-----GLDLNVVDagddpAVQERQLAEAEA-QSKVVIVNPtdsDEVRGSVEK 108 Corynebacterium py...

Feature 1                ##                                                    #   #          
1URP_D     78 ANQaNIPVITLDRqat-kgeVVSHIASDNvLGGKIAGDYIAkka-----gegAKVIELQGIAGtsAARERGEGFQQAvaa 151 Escherichia coli K-12
2DRI_A     78 ANQaNIPVITLDRqat-kgeVVSHIASDNvLGGKIAGDYIAkka-----gegAKVIELQGIAGtsAARERGEGFQQAvaa 151 Escherichia coli
KHG65698  101 ANQaGIPVITVDRaas-ggkVAYHIASDNvAGGRMAAEFICnll-----kgrGKVVELEGIPGtsAARDRGQGFNAYlke 174 Thermus sp. 2.9
APZ41703  109 ANRaGVPVIFVDRktd-agkAIGFFASDNvQAGEQACNYISqrl-----hgkGQIAMLLGIPGasATNERSAGCETAlkk 182 Acidihalobacter fe...
CUH95937  118 ANKaNIPVITVDRsae-ggkVVSAIASDNvAGGKMAAQLLIdkl-----ggkGKVVELEGIPGssAANDRGKGFDDAmka 191 Propionispora sp. ...
NP_600477 114 LNQaDIPVVAVDRssn-ggeVASFVASDNvAGGAQAAAALAeai-----ggeGEILMLQGIAGssASRDRGQGFEEEiak 187 Corynebacterium gl...
CRH66959  112 LLSsGMPVISVDRsvt-gekVTSHIASDNvAGGAQAADALAksm-----gekGEVLILQGIPGaaSTRDRGKGFKDRikk 185 Chlamydia trachomatis
AFK51429  119 AKSaGIPVVTTDRdvadktlRFVFIGTDNvKGAEQAANALIqaltesgkptpWKVVILNGIPGttAAIDRNKGFHNVldp 198 Thermogladius cell...
OQX07684  385 AHEaGIKVITVDRkssrddlVLSHVASDNaQGGQMAAEFIAkkl-----kgkGNILELEGIPGtsAAHERGMGFDKAigk 459 Desulfobacteraceae...
EPD68668  109 LNEkGVPVITLDRavn-ggeVAAHISSDNvEGGREAAGELAksi-----reqGEVIVLTGLEGssSSEDRLAGFQEKias 182 Corynebacterium py...

Feature 1                     #                         #                           #         
1URP_D    152 ----hkFNVLASQPADFDRIKGLNVMQNLLTahpdvqAVFAQNDEMALGALRALQTAgk---sdVMVVGFDGtpDGEKAV 224 Escherichia coli K-12
2DRI_A    152 ----hkFNVLASQPADFDRIKGLNVMQNLLTahpdvqAVFAQNDEMALGALRALQTAgk---sdVMVVGFDGtpDGEKAV 224 Escherichia coli
KHG65698  175 k--cpgVTVVARQTANFDRAQGLSVMENILQaqrdidAVFAHNDEMALGALQAIKASgr----kIPVVGFDAtpDAVKAV 248 Thermus sp. 2.9
APZ41703  183 ---hpgIHIVARQTANFSREDGLNVMRNVLIahpnldAVYAENGQMGIGAMKAIDSAstqhkpfIVIVGSNSp-YQQKLI 258 Acidihalobacter fe...
CUH95937  192 ---aagISIVAKQPADFDRAKGMKVMENILQanpeiqAVFAQNDEMALGAVEAIKAVnr---tnVLVVGFDAtaDAVTAV 265 Propionispora sp. ...
NP_600477 188 ---hegISIVAKQTANFDRGEGLDVATNLLQahpnvkAIFAENDEMALGAIEALGARag---edVIVVGFDGtnDGLAAV 261 Corynebacterium gl...
CRH66959  186 ---ypnIKVVAEQTANFDRAEALNVATNLLQshpnaaGIYAENDEMALGAIQSLGAKag---kdVKVVGFDGtaDGMKAI 259 Chlamydia trachomatis
AFK51429  199 lvsqgkVVIVAEEVANFRRDEALSKMESILAakk-vdAVIAANDEMALGAIQAIKGAgltpgkdIIVVGYDAipDAVAAV 277 Thermogladius cell...
OQX07684  460 ---ypeIKIIAREAADFDKAKAAEVVKQFIQkglsvdAVFAHNDNMILGAIEAYGSKtp----kPMFVGFDAipEATEAV 532 Desulfobacteraceae...
EPD68668  183 ---ypkIRVVAVEAADFERSTAREVVQQLLAahpdvaGIFAENDEMALGAVEALGERag---kdVKVIGFDGteEGVRAV 256 Corynebacterium py...

Feature 1               #                                     
1URP_D    225 ndGKLAATIAQLpDQIGAKGVETADKvlkg---ekvqAKYPVDLKLVV 269 Escherichia coli K-12
2DRI_A    225 ndGKLAATIAQLpDQIGAKGVETADKvlkg---ekvqAKYPVDLKLVV 269 Escherichia coli
KHG65698  249 eaCEMAATVAQQpAEMGRFAVEKAVElirgakapaqtQFIPVPLKLVT 296 Thermus sp. 2.9
APZ41703  259 keGKIALSVAQQpGKMVAMAIEAGQHylq-----dgvLFVPVPLMMDK 301 Acidihalobacter ferrooxidans
CUH95937  266 nsGDMLATVAQKpKDMGKISIETAIKimng---eavaASIPVPLELIV 310 Propionispora sp. Iso2/2
NP_600477 262 edGRMLATVAQQpEELGAKAVEEAAKllrg---edaeTEVPVEVVTVK 306 Corynebacterium glutamicum ATCC 13032
CRH66959  260 kaGTMAGTIAQQpKELGRSAVAAAVKaikk---qtvpKTEPITVKTVT 304 Chlamydia trachomatis
AFK51429  278 kaGEMYATIAQSpFLQGYWGILAAYYrvtqn-wnppaDWIPTPTVVVT 324 Thermogladius cellulolyticus 1633
OQX07684  533 kqKKLTATIAQKpEIMGARAVQTATQalrg---ekvsKALPVELDLIE 577 Desulfobacteraceae bacterium IS3
EPD68668  257 knRQLIATVAQLsSELGARAVEEAGTildg---gtpdKEIATNVVVVT 301 Corynebacterium pyruviciproducens ATCC BAA-1742

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap