Conserved Protein Domain Family
Ntox15
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pfam15604: Ntox15 
Novel toxin 15
A predicted RNase toxin found in bacterial polymorphic toxin systems. The toxin possesses a most all-alpha helical fold and a conserved HxxD motif. In bacterial polymorphic toxin systems, the toxin is usually exported by the type 2, type 6, type 7 or Photorhabdus virulence cassette (PVC)-type secretion systems. This is shown to be a type IV secretion system protein that behaves as DNase.
Links
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Statistics
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PSSM-Id: 406122
Aligned: 6 rows
Threshold Bit Score: 190.489
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q883B1               348 QKYLKTYSAQLRAQQDAINNMTAEEFKSARDSYKNLGRNPAADAMQRRMGkqmerevAEKIQKSLVKKGV-DVREAiiQA 426 Pseudom...
BAK15743              51 KHDSEEFARQLKDQEKGMNELTVDEYLKNREKYIEQGRAIEGNAAQQAAR-------EKALNKKIEELFEnGMSWE--EV 121
jcvi:HMPREF9154_2249 120 SQHPAEFARQLSRQYEALSYLTVDEYLKGRDLYKTNKRAPNSSAIETD---------RAGLEKQIVIRLVrEYRFDpdKA 190
jcvi:HMPREF9154_0815 115 SQHPAEFARQLSRQYEALSYLTVDEYLKGRNLYNTQKRAPTPPSLELQ---------REDLEKKIVNRLVdDYRFDpdKA 185
AAK89090              99 PKQVEEFRRQLKEQQDEINRMEPDDLVRNIDKYRQQGRPTDDAANRRQSRedyrtdrTRELEEKYLSKGRnDYKE---QA 175
KEY50698             115 TIDIDEFKRQMELQEQGLNNMSPQQMLANQAKYLANPAGMRALSEPLQAKarqeyrnDPRIQKKYVD------QYGpiQG 188 Agrobac...

Q883B1               427 KARAKEIKSTVAALHEPDMVAGGwlsp-------dpvrMGSSSVNSSIGGSW-------SSRLKALDDA----VDSAMLD 488 Pseudom...
BAK15743             122 EKNANSWLKSQAALHNPDQIAGGkpln--------iggMGDKRINSSIGSQW-------KYRIDIVDEQigelTKSLTSD 186
jcvi:HMPREF9154_2249 191 EEKAAEAVQSLAALHEPDQSLQGthqlt-----sgeivWGNGPVNSSIGGQH-------KPGVALLDKK----ARAAQQA 254
jcvi:HMPREF9154_0815 186 EKKAVEAVQALAALHEPDQSLQGthqla-----ageivWGNSSVNSSIGGQH-------KAGLARLDEK----ARDAQVA 249
AAK89090             176 ANDVAEEMKKLAATHTLDLVAGGdgs---------isgLGDKSINSSLGSQW-------KGRRSEQLRS----HAKKAAE 235
KEY50698             189 PIKLGEYLDSAAALHNPDMIAGGkynsvvdqtlpienrIGGLSENSSMGSQWinpnrngHTRASRLTEH----AKRQAAN 264 Agrobac...

Q883B1               489 GNGGAKLNVRLN 500 Pseudomonas syringae pv. tomato
BAK15743             187 QRKNTYLNVKLT 198
jcvi:HMPREF9154_2249 255 GKGQHYLNVRVV 266
jcvi:HMPREF9154_0815 250 GKGHRYLNVRVV 261
AAK89090             236 QKKKMNAKLEEC 247
KEY50698             265 NCPSVQVDLRLC 276 Agrobacterium tumefaciens
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