Conserved Protein Domain Family
FIG

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cl00289: FIG Superfamily 
FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in gluconeogenesis. Inositol-monophosphatases and inositol polyphosphatases play vital roles in eukaryotic signalling, as they participate in metabolizing the messenger molecule Inositol-1,4,5-triphosphate. Many of these enzymes are inhibited by Li+.
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Statistics
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Accession: cl00289
PSSM Id: 469707
Name: FIG
Created: 8-Feb-2008
Updated: 4-Oct-2023
Superfamily
Curated CD Hierarchy
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