4S2T,1WBQ,4B28,1Y1N,3S6B,3CB6,6A8M,3BIT,5CDV,5CNX,1PV9,2ZSG


Conserved Protein Domain Family
Peptidase_M24

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pfam00557: Peptidase_M24 
Metallopeptidase family M24
This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Statistics
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PSSM-Id: 459852
Aligned: 382 rows
Threshold Bit Score: 71.1182
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4S2T_Q       347 QGMRNSHLRDSAALVEF-LCW--LE---KellsgkRYTEIELADKIDh-LrSLQDK-------YVTL-SFDTISAVGDHA 411 Caenorhabditis ...
Q9PQN9        11 AAIKEAVRIWKIAREAI------YKqakA------GVSLKELDLLAKevI--EANGgia--afHNYL-GFKGHICISVNE 73  Ureaplasma parvum
Q8EUD4        11 EQIKKACSVWKKVRQAL------IEnaaA------GKSLIELDELAKkvT--IENDctt--pfHQYR-GFPGYNCISVND 73  Mycoplasma pene...
O52353        11 QKIKNAAQIYKKIVKQF--NFdyIK----------NKSLKEIDQMLRd-F--VSQHhan--scYHGYlGFKGYHCLSLNQ 73  Mycoplasma gall...
O84859        50 EKIRKACQVTAHILDAL-CEA--AK---E------GVTTNELDLLSRe-L-HKRHNaipaplnYGHP-PFPKTICTSLNE 114 Chlamydia trach...
XP_001611993  91 ALMRAAAKIAAGCLKHC------INitkE------GVTAEDIDREGHeyI--VSQGsyp--agVGFH-GFPKAICISINE 153
Q5KLT3       126 EGMRKVCRLAREVLDLV-ASH--IK---P------GVTTDELDAICHq-A-CIDRNsyp--spLNYV-KFPKSICTSVNE 188 Cryptococcus ne...
Q9CPW9        95 QGLREACRLARHVLLLAgKS---LK---V------DMTTEEIDALVHw-E-IIRHDayp--spLGYG-RFPKSVCTSVNN 157 house mouse
Q6Z4B5       121 AGMRAACKLAARALDFAgTL---IK---P------SVTTNEIDREVHn-M-IIEAGayp--sqLGYG-GFPKSICTSLNE 183 Japanese rice
WP_004844059  49 EKIKKSAALNTAVLDEV-AAH--IR---A------GMSTAEIDKIVYd-FtTAHGGip---apLNYQ-GFPKSVCTSINN 111 [Ruminococcus] ...
4S2T_Q       412 ALPHY-KP---LGesgnrkAAANQVFLLDSGAHYgdGTTDVTRTVWYTNPPK---Ef------ILHNTLVLKGHINLAR- 477 Caenorhabditis ...
Q9PQN9        74 CVIHG-VPt-dYV------LKDGDKVTFDVGVKYdnHYCDAAFTIIIN--NSnveAl------K-ISEICKKSIDEAVA- 135 Ureaplasma parvum
Q8EUD4        74 VVIHG-VPt-nYK------LKDKDMVTFDVGVAYngYICDAAFTVII---GEnveAq------K-INDVCYKSLIEGIK- 134 Mycoplasma pene...
O52353        74 TIIHGlANd--EI------FTSKDKLTIDIGIELdnYYCDSAFTI-LG--PDvnpRq------KLLSEVTHNCIFELVKk 136 Mycoplasma gall...
O84859       115 VICHG-IPn-dIP------LQNGDIMNIDVSCIVdgFYGDCSRMVMIGEVSE---Ik------RKVCEASLEALNAAIS- 176 Chlamydia trach...
XP_001611993 154 VACHG-IPn-tRP------FQRGDIVSYDCTVFHggVYGDCAGTIIVG--DD---SatdasgsL-LVRIAKECVDKAIA- 218
Q5KLT3       189 VICHG-IPd-qRP------LQEGDIINLDVTLYHggFHGDLNATYPVGKVDQ---Es------QDLMDTTKKAMDEAIA- 250 Cryptococcus ne...
Q9CPW9       158 VLCHG-IPd-sRP------LQDGDIINIDVTVYYngYHGDTSETFLVG-------Nvde-sgkK-LVEVARRCRDEAIA- 219 house mouse
Q6Z4B5       184 CVCHG-VPd-sTQ------LQTGDIMNVDVNVFLngYHGGASRTFVCG-------Evdd-sirH-FLKAAEECLEKGIT- 245 Japanese rice
WP_004844059 112 EVCHG-IPdenII------LQEGDIINVDVSTILdgYFSDASRMFMIGEVSD---Ra------KRLVRVTEECVELGLA- 174 [Ruminococcus] ...
4S2T_Q       478 AKFPdGIYGSRLDTLTRDALW--KLG-L-DFEHGTG-HGVGhyLNVHe-gP------I-GIghrsVP-TGGELHASQVLT 543 Caenorhabditis ...
Q9PQN9       136 IIKP-KVTTHAISNAIQKFIE--KNGyFvL-RDFAG-HGCG--NEIHe-dPlipnyrSlLY-----R--NVTLEENMVIC 200 Ureaplasma parvum
Q8EUD4       135 QIKP-GNRIGDISNAIEEYVV--SNGyYiL-EDFGG-HGCG--RKLHe-dP------IiLNyg-vKN-SGPIIKPNMVLC 198 Mycoplasma pene...
O52353       137 IV-PnQTTTNDLGIWTEEYAK--KYG-YsV-IKDFGgHGCG--IKIHe-dP------IiLNyg-tKK-SSELLTPNMVIC 200 Mycoplasma gall...
O84859       177 ILEP-NLPLYEIGEVIENCAA--KYG-FsVVDQFVG-HGVG--VKFHe-nP------F-VAhh-rNS-CKIPLAPGMIFT 239 Chlamydia trach...
XP_001611993 219 SVAP-GVEFSKLAEIVTEHASknSLGvI---KEFGG-HFIG---DMMhmpP------M-VQfc-hPStTRGQMESGQIFT 282
Q5KLT3       251 LCKP-GVPYREIGNKIEEIIK--PKG-FgIVRRYTG-HGIH--HLFHc-lP------T-IVhyggSK-TPGRMEAGQVFT 314 Cryptococcus ne...
Q9CPW9       220 ACRA-GAPFSVIGNTISRITHq-N-G-LqVCPHFVG-HGIG--SYFHg-hP------E-IWhh-aND-NDLPMEEGMAFT 282 house mouse
Q6Z4B5       246 VCRD-GVNYKKIGKKISKLAYf-Y-G-YyVVDRFVG-HGIG--PIWHs-eP------L-ILhh-aND-NSGRMVEGQTFT 308 Japanese rice
WP_004844059 175 AAKPwG-HLGDIADAINTHAQ--ANG-YsVVVDIGG-HGIG--LEFHe-dP------F-VSyvtpKG-SEMLLVPGMMFT 238 [Ruminococcus] ...
4S2T_Q       544 IEP---------------GFY-----A-K----------EK-----------------Y-GIRIENCYETVE 566 Caenorhabditis elegans
Q9PQN9       201 IEPmi-----------lsGSNayyidPnD----------QWsvks----------knhQmTCHWEHMILITK 241 Ureaplasma parvum
Q8EUD4       199 IEPmilt--------edaSYYi----DkD----------KWsvia----------snhKlSCHWEHMVLVTN 238 Mycoplasma penetrans
O52353       201 IEPmffe--------kdnRYY-----IdPd--------dSWsvkp---------vnknQyVCHWEHMVLIKE 242 Mycoplasma gallisepticu...
O84859       240 IEP---------------MINvg----------------kKegfidpinhweartcdhQpSAQWEHAILITD 280 Chlamydia trachomatis D...
XP_001611993 283 IEPiice--------gnpEIYt----WrD----------GWtiat----------cdgGrCAQFEHTVLVTD 322
Q5KLT3       315 IEP---------------MVNlgtsnL-E----------HWnddwta-----vtsdgrR-SAQFEETILITE 354 Cryptococcus neoformans
Q9CPW9       283 IEPiite--------gspEFKv----L-EdawtvvsldnQR-------------------SAQFEHTVLITP 322 house mouse
Q6Z4B5       309 IEPiltm--------ekaETVt----W-EdgwttvtadgSW-------------------AAQFKHTVLVTR 348 Japanese rice
WP_004844059 239 IEPminegspdffvdednD---------------------Wtiyt----------iddGlSAQIEYMVLVKE 279 [Ruminococcus] gnavus
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