6XBZ


Conserved Protein Domain Family
MAT1

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pfam06391: MAT1 
CDK-activating kinase assembly factor MAT1
MAT1 is an assembly/targeting factor for cyclin-dependent kinase-activating kinase (CAK), which interacts with the transcription factor TFIIH. The domain found to the N-terminal side of this domain is a C3HC4 RING finger.
Statistics
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PSSM-Id: 461894
Aligned: 52 rows
Threshold Bit Score: 182.055
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6XBZ_H        72 LRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDF-PSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKD 150
ESW95774      64 LRKNRFKTQIFDDVDVERECDVRKRVVSVYNKTQEDF-KSLDEYNAYLEEIEDYVYKLVNKIDVEQTEQKLKEYQQAHKH 142
Q6CT73        60 LRRNKFKTQIFDDVGVEKEVDIRKRVFNVFNKTLEDFdNNQDDYDKYLEEVEDIIYNLDHGIDMEKTEERLRTYEELNKQ 139 Kluyveromyces l...
XP_003646011  60 LRKNKFKTQIFDDVDVEKEVDIRKRVFNVFSKNLEDFdGDLDAFNKYLEEVEDIIYNLDNGVDVAKNEEKLRTYEELNKQ 139
XP_002555255  62 LRKNKFKTQVFDDVNVEKEVDIRKRVFNVFNKTLDDFeGDLKAFNKYLEEVEDIVYNLDNGIDVANTEEKLRTYEDLNKQ 141
CCC67351      61 LRKNKFKTQVFDDVAVEKEVDIRKRVFNVFNKTLDDFdNDLDKYNKYLEQVEDIIYNLDHGIDVVETEEKLRSYEELNKQ 140
Q6FMP4        73 LRKNKFKTQIFDDVGVEKEVDIRKRVFNVFNKTLEDFdNDLEAYNKYLEEVEDIVYKLDNKIDVVETEEKLRTYEELNKQ 152 [Candida] glabr...
CCF59891      71 LRKNKFKTQIFDDVGVEKEVDIRKRVFNVFNKTLSDFgGNMDEYNIYLEEVEDIVFNLDHGIDVVKTEEKLRTYEELNKQ 150
CCE65159      61 LRKNKFKTQVFDDVGVEKEVDIRKRVFNVFNKTLEDFdGNLDEFNKYLEEMEDIIYNLDHGIDVEDTEEKLHSYEELNRQ 140
XP_003671525 104 LRKNKFKTQIFDDVGVEKEVDIRKRVFGVFNKDLNDFdGDLKKFNEYLEHVEEIVYKLDHGIDVEETERQLKDYEELNKQ 183
6XBZ_H       151 VIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDL----------------PVA 214
ESW95774     143 DIEMSNNQRDQEYEKFLKLQNLEKRYKAEKNKINREIIKEEQNLKNLSKLEVINQLQTASGe--------------kDAD 208
Q6CT73       140 LIMANLERSKQDVANFEQRQKFEKEMKLKKRLLEKQIEEEERANREWAKREIVNQLTVNE-----------------DAE 202 Kluyveromyces l...
XP_003646011 140 LIMANMERNKQFLENFEQRKKFEKEMKLKKRMLERQIEEEERANKEWAKREIVNQLSSNI-----------------DAD 202
XP_002555255 142 LIMANMKRSRQDLDNFEQRQKFEKEMKLKKRQLERQIEEEELANREWARKEIVNQLSTAD-----------------DAE 204
CCC67351     141 LILNNIERNKKDLENFEQRNKFEKEMKLKKRMLERQIEEEDRSNKEWAKKEIINRLSQSN-----------------DAE 203
Q6FMP4       153 LIMNNMERSKKDLENFEQRQQFEKEMRMKKRMLERQIESEDKMNKEWAKREIVNRLASST-----------------NAD 215 [Candida] glabr...
CCF59891     151 LILNNMERNKQDTENFAARQQFEKEMKLKKRLLEKQIEEEERFNKEWAKKEIVNRLTSSNSi---------------DTE 215
CCE65159     141 LILNNIERNRQELQNFEQRQHFEKEMKMKKRMLEKQIDEEDKMNKEWARREIVNRLTTTA-----------------STE 203
XP_003671525 184 LILSNIERNKKEFENFEEREKFQKEMRLKKRMLERQIEEEDKSNKEWAKREIINRLAAASTsgslssassastsivdNTQ 263
6XBZ_H       215 LLLAQHKDRSTQL-------EmqlekpkpVKPVTFSTGIKMGQhisLAPIHKL-EEALYEYQP 269
ESW95774     209 KIIANVRDSMISKtsnykeqLeeleknyqEQREKIINGLDEL---------KEeEKPKVPFTP 262
Q6CT73       203 EVIENVKKTVKLKkssarrkLeelnkvlrNNPYMTMTN--------GRMKKKD----TVPFTP 253 Kluyveromyces lactis NRRL Y-1140
XP_003646011 203 EVIENVRKTVKLKkssarrkLqelnkvlrNNPYMQMSN--------GTMKKQE----KVPFTP 253
XP_002555255 205 DVIAHVKKTVKLKkssarrkLeelnkvlkNNPYMTVSN--------GLMKKKE----SVPFTP 255
CCC67351     204 EVIEGVKNTVKLKkssarrkLdelnrvlkNNPYFASSNPNSNQn-lMLLRKQKeMESSIPFTP 265
Q6FMP4       216 DVIEGVKNTVKLKkssarrkLeeinrvlqNNPYSSLMLs------qGLSRKED----NVPFTP 268 [Candida] glabrata CBS 138
CCF59891     216 DVIEGVKNTVKLKkssarrkLeelnrvlkSNPYFSSNS--------NVSRKKD----MVPFTP 266
CCE65159     204 DVIEGVKNTVKLKkssarrkLeeinrvlkSNSYLASTVg------lNASRIKK----SVPFTP 256
XP_003671525 264 DVIESVKSTVKLKkssarrkLdelnrflqDNPYFSSSNPNSTQn-tLLYQQQH-GGSVIPFTP 324
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