2MXF


Conserved Protein Domain Family
MvaT_DBD
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cd16170: MvaT_DBD 
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DNA-binding domain of the bacterial xenogeneic silencer MvaT
MvaT is a xenogeneic silencer conserved in Pseudomonas which assists in distinguishing foreign from self DNA. It prefers binding to flexible DNA segments with multiple TpA steps, and forms nucleoprotein filaments through cooperative polymerization.
Links
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Statistics
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PSSM-Id: 320084
Aligned: 23 rows
Threshold Bit Score: 62.3844
Created: 18-Aug-2016
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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DNA binding
Conserved site includes 14 residues -Click on image for an interactive view with Cn3D
Feature 1:DNA binding site [nucleic acid binding site]
Evidence:
  • Structure:2MXF: Pseudomonas aeruginosa MvaT binds DNA, contacts at 4A
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1        ## # #          #####  # ##  #        #    
2MXF_A         5 RKVKQYKNPHTGEVIETKGGNh-KTLKEWKAKWGpEAVESWAT 46  Pseudomonas aeruginosa PAO1
WP_036566315  73 RTPTKYKNPETGEVIEVRGGRq-KNYQDWIQQYGkETVQGWRL 114 Oceanospirillum beijerinckii
WP_019473237  84 RRSKYYINPHTGQEVEAKSTLh-KTVRLWIQQYGrEEVESWAT 125 Pseudomonas
WP_017429367  78 KPTRHYRNPHNGETVQAKSFRn-ATLREWVKQYSrETVEGWEV 119 Halomonas jeotgali
WP_044618253 121 LEIGIYTNPHTQQTVEKKRRNp-KELDAWLDEYGyDTVVAWKQ 162 Gynuella sunshinyii
WP_020414422 117 LETGHYRNPYTGATVEKKKRNp-KALSQWIDEYGlDTVKEWKI 158 Microbulbifer variabilis
WP_036535063 111 LEVGEYTNPNTGETVEKIKRNp-RQLDQWIAEHGiETVKGWKS 152 Oceanobacter kriegii
WP_037337388 110 LDIGVYVHPNTGERIEKKRRNp-KTLDEWIEAFGiEEVAQWRE 151 Saccharospirillum impatiens
WP_023121237  77 FKKKVYTNPQTGQQVHRAGGPfpSLLKSWMDAHGkEEVESWAK 119 Pseudomonas aeruginosa
WP_044871349  48 QAKKTYRNPFNGHCIHLRAGKn-LTYRAWILQYGeATVESWLI 89  Pseudomonas sp. LFM046

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