2JZ4,2JZ4,3AQG


Conserved Protein Domain Family
Jacalin
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smart00915: Jacalin 
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Jacalin-like lectin domain
This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.
Links
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Statistics
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PSSM-Id: 214909
Aligned: 106 rows
Threshold Bit Score: 70.3361
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2JZ4_A       164 GTAWDD-----GAYD---G------V---KK--VYVGQG---QDGISAVKFEY--NKGAEnIVGGEHGKpTLLGFeeFEI 219  thale cress
NP_001102293  31 vkgeDV-----GDLK---G------I---R----IFLSL---LNFIKGIQLRF--GND----WSDVYGSrSLKYK--EFL 78   Norway rat
EDM03795      26 GTYFYV-----AGEE---H------GqlrGL--RIFLTV---IDLIKGIQLRF--GGN----WSDVYGSrSLKYK--EFL 78   Norway rat
YP_001208179 291 rrlsdqfggphgtsyndvsalpanpV---PS--KLTIRT---GSRVDQVELTL--SNGYV-F---SHGGtGGTAQ--SLT 354  Bradyrhizobium...
NP_035451     26 GKYFYVq----GEDQ---G------Q---LKgmRIFLSV---FKFIKGFQLQF--GSN----WTDVYGTrSDNFI--DFL 78   house mouse
XP_749904    306 GTWFNDldslpTAFT---G------Q---NKpsKISLRG---AERLDSVGLTV--ASGK----SYTHGGtGGQLS--ELP 362  Aspergillus fu...
NP_828383    316 GDYFND-----IDSVpagA------R---AT--TVSLRS---GSRVDRMGLTL--GNGT----TLAHGGtGGTAS--SLT 368  Streptomyces a...
ZP_08187712  305 GVPFNDva--gGAHQ---R------Q---LR--SVTLRG---AERLDAVAASL--DNGA----TLAHGGsGGTAT--TLA 357  Xanthomonas pe...
XP_958199    322 GNWFND-----VSAL---DsttgsiK---AQ--KITFRG---ENRLDSVGLTVlsSSGQG-TTELVHGGqGGSEV--SLT 382  Neurospora cra...
YP_001098389 824 gggWSD-----AA-Q---C------Q---KQ--HVVAFNvssGKRLDGIQFQY--ANGQ---WGAVHGKlK-NKK--AYA 875  Herminiimonas ...

2JZ4_A       220 DYPSEYITAVEGTYD-KIfgsdgLIIT---ML--R--F--K--TNK-QTSAPFGLEa--GTAFELK-EEGhKIVGFHGKA 283  thale cress
NP_001102293  79 LEDGEHVTQVSGTRK--------LCLT---SL--S--F--T--TNKeRALTFGVRt--gRSFDDSGgSDKhLVTVNGTHT 137  Norway rat
EDM03795      79 LEDGEHVTQVSGTRK--------LCLT---SL--S--F--T--TNKgRVVTFGVRRg--LSFNESGgSDKyLVTVNGLYA 137  Norway rat
YP_001208179 355 LASGEYLTSVNLCSA-QYq----GHTR---IF--WvsF--A--TSTgRM--LAGGAttsSC-TSYTaPGGwQITGFHGR- 416  Bradyrhizobium...
NP_035451     79 LEDGEHVIKVEGS---AV-----ICLT---SL--T--F--T--TNKgRVATFGVRRg--RYFSDTGgSDKhLVTVNGMHA 137  house mouse
XP_749904    363 LAANEYWTKAKLCQG-QYr----GHTR---NF--Y--LlaT--TSSgRT--VSAGTatsDCK-EFAaAPGwQIVGFYGQ- 424  Aspergillus fu...
NP_828383    369 LGSGEYVTSAHLCQGvKD-----GHTR---IFyaK--F--T--TNLgN--SLAGGTttsDCVTRTAp-SGrQIAGFHGR- 430  Streptomyces a...
ZP_08187712  358 LRSGETLTAATVTLG-QY-----NGRTrlfSL--S--L--T--TNQgRS---IAAGtptSERYTLTaPTGwHIAGFTGR- 419  Xanthomonas pe...
XP_958199    383 LTDGESWVKSELCQGqKS-----DKTR---NF--Y--I--KatTSKgRTLEAGTRTsdcK---VFEaEEGwQVVGFLG-E 444  Neurospora cra...
YP_001098389 876 LPAGQYIVRVD--YR-GG-----GSMD---AV--G--F--T--TNTgTSYGP--FGgggGSAGTYTvTPGqKLGCMAGR- 933  Herminiimonas ...

2JZ4_A       284 SEL-LHQFGVHVMP 296  thale cress
NP_001102293 138 PGLcITGMGFKWev 151  Norway rat
EDM03795     138 PGLcLNGMGFKWkn 151  Norway rat
YP_001208179 417 SGDgVDKLGVVYAP 430  Bradyrhizobium sp. ORS278
NP_035451    138 PGLcVRGIGFKWGn 151  house mouse
XP_749904    425 DGDeIDQLGFLYGl 438  Aspergillus fumigatus Af293
NP_828383    431 AGDeVDKIGFIYTq 444  Streptomyces avermitilis MA-4680
ZP_08187712  420 AGDaIDKLGVIYRk 433  Xanthomonas perforans 91-118
XP_958199    445 SGDeVDLLGFIYSk 458  Neurospora crassa OR74A
YP_001098389 934 SGSeVDQLIFsstg 947  Herminiimonas arsenicoxydans
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