Conserved Protein Domain Family
COG4692

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COG4692: COG4692 
Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis]
Statistics
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PSSM-Id: 443727
Aligned: 99 rows
Threshold Bit Score: 275.653
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
SQF98076       1 MRIKrlrvpaigvyLAISCLFAAAWWtnpatphssfalmrpvlavaGQVAK---PIYTSRFAsSGLVDFVHSSAVTALPD 77 
WP_011684414  61 MR--------------IFALFLCALa-------------------cAAATP---EYSGELIF-PLEKWHNHSSSVVELPN 103
WP_013564483   1 MFRKwrd-----saAWLTLAWGAAGlla---------------aarADEPNa--PVKRDLFA-NDAVYHNHASCVVECPN 57 
WP_013665185   1 MRHh----------FIFYAIFLLFsi------------------tlRAQPK---VAEATLIF-PLQAKHVHGSSLAVLPN 48 
WP_014020105   1 MNK-----------IVFLGLYLLSVSafg--------------qyiPKEKV---LVSESLIF-PLQQNHVHGSSIVSLPN 51 
WP_067550617   1 MKAl----------LLAFFVFISHLas-----------------lkAQTSP---ILQSQLIF-PLQEKHVHASSIVSLPN 49 
WP_110173263  17 MQRVvk-------aGILAAVVAAVTTvwpalr--------arpvvaAQAPPprgHYRSELLF-PVEHWHNHSSSIVEHPD 80 
WP_083731940  48 MTKa----------TVLLAMFVAAGgv-----------------psAFGQS---TLTSELVF-PLDQRHNHAPGIVELEN 96 
WP_010040162 474 LVKdaap------------------------------------tpsLKKEGkdgSFAAELIF-PLHKQHNHAPGIVECPN 516
WP_119754826   1 MTYLdk-------tILLFLILLVSNgcr---------------pptTKPPGq--SLRTNLIF-PLQDEHVHGSTLVELPN 55 
SQF98076      78 GsLMTVWFAGSREGAA-DVQVRSALFDasTGEWGAEQVLAtrattQQgTqrfIRKLGNPVVALAPDNRLWLFYVSVSMGG 156
WP_011684414 104 GdLLVCWFHGSGELTAdDVLIQAARWNhtTKQWSAPFTLA-----DT-P---GFPETNPVLFLDSHQRLFFAWPLIVAHK 174
WP_013564483  58 SdLLVAWYRGSGERDAdDVEILAARLKkgQTTWGPVFPLI-----DT-P---GYPDCNPALLVGDDGSFWVFRPTILDHR 128
WP_013665185  49 GdVLAAWFYGSGERGAdDVCIMGSRKRaeSKTWSKPFLMA-----DT-K---GIPDCNPVLFLNHKKQLYLAWIAVQANR 119
WP_014020105  52 GdLLTAWFEGSGERKAdDVRIMGARLRkkDRQWGEPFLMA-----DT-P---NIPDCNPVLFLNQEGKLFLVWIAVQANR 122
WP_067550617  50 QdLLAVWFEGSGERTAnDVLLMGARLKvgSLNWSKPFVMA-----DT-P---NLPDCNPVLFLNGEGKLFLVWIAVQANR 120
WP_110173263  81 GhLLVTWFHGSGERTAdDVELLGAWQRkgTTTWTAPARLA-----DT-P---GYPDTNPTLFVDRTARLWLLWPTILANE 151
WP_083731940  97 GeLLVSWYRGSGERKAdDVAVYGARKPvgSKTWSDPFRMV-----DT-P---GFPDCNTCMMIDRHNRLCLYWPVIIANT 167
WP_010040162 517 GdLLVSWYRGSGERSAdDVAVYGARKKagADTWSDAFLMA-----DT-P---GFPDCNTTMWVDKDGKLWLFWPLILANS 587
WP_119754826  56 GdLLSAWFQGSGERWAdDVRIMGSRLIkgDTAWSAPFVMA-----DT-Y---DFPDINPILFMDKQQRLWLMWYVVLANQ 126
SQF98076     157 WAGSAvnvMVSDDFG-----RNWSA-----------------PRQ---------------------LITSpf-------- 185
WP_011684414 175 WETALmkyRISTDYQqpsgpPKWEFqdni----------vliPKDia------------------aLTKEfagaeaagtg 226
WP_013564483 129 WEGALlkfARADACPegdaaPVWNRegvl----------hltPVGlseaiq----------asldrLPEEirahprlggy 188
WP_013665185 120 WEQSIlryRVADEYEgs-aaPNWGWqdni----------llkPDSsfaqel---------keklsmLPDQqhgwaayapp 179
WP_014020105 123 WEQSIlrfRTSTSYEna-gaPIWSWqdni----------llkPGEefhqev---------akrfeqLPENnsgwseyapq 182
WP_067550617 121 WEQSIlrvKIATDFEsd-gpPRWSWqdni----------flnPGDefseev---------vrrfqeLPKNtagwaeyaps 180
WP_110173263 152 WHTALmkvKTARTWPvg-evPHWDTsevm----------hitPGDrfaevtrr-----eadrlaaaLPQGeagakargyl 215
WP_083731940 168 WESCLtfyKVSDQPTgk-gsPEWSDggvi----------llkPEDfgpkaiqv------ldeeiakLPTQladaystels 230
WP_010040162 588 WESCLtsyRVSSDYQtg-gaPKWEWqgti----------plkPKDfegvmlre------feawkkqVAAAskmpfepdaa 650
WP_119754826 127 WETSLlmyARSEDYDqp-gmPEWKTknvllvkvgdktergiqPDDkfvrevddqlheyedylkttlLPEApdslrqmlmt 205
SQF98076     186 ----------------------------------------lnISTLVRSAPVFHADGSIGLPVYHEflGKFAEYLYLSAD 225
WP_011684414 227 pradr----------------------akkqiehaedeyfsrMGWFTRTHPLELPSGRILMPMYSD--GYSYGIMAISDD 282
WP_013564483 189 lde---------------------------vdarrddelyqrLGWMPRCRPVILSTGRWILPLYTD--TYSVSLMAYSDD 239
WP_013665185 180 yde--------------------------mivtnaqdpakrsFGWMTRIKPLLLADNKILLPLYSD--GFNCSLIAVSED 231
WP_014020105 183 ydq--------------------------miieaskdskkssIGWMTRIKPVVLTSGRILLPLYSD--GFNFSMMAISDD 234
WP_067550617 181 ydr--------------------------mileaaqdpkkrtTGWMTRIKPLVLETGKIILPLYSD--GYNFSMMAISED 232
WP_110173263 216 ek----------------------------lktdaadkltrrLGWMTRVHPLQLEDGRIIVPLYSD--GFSFSLMAISDD 265
WP_083731940 231 dl-----------------------------relltqklyqrLGWQPRCKPTVLPSGRILLPLYSD--TYSICIMAISDD 279
WP_010040162 651 pl-----------------------------kkkvgdkllsrLGWQPRCKPVVLGTGRVLLPLYSD--TYDAGLMALSDD 699
WP_119754826 206 dwkayrnkmdslargrnmlrsgritddahdtsvklgypltrrLGWQTKNKAI-YAGHRLILPLYTD--GFDGSLFALSDD 282
SQF98076     226 -GNVIDKF-RIShGNNSLQPTVVPLDGQRGIALLRYAGntHHRVLATRTEDAGQSWSEPYPLYPSNPNSSLAAVATPEHG 303
WP_011684414 283 gGYTWTASqPIV-GEGCIQPSVVRKKDGSLVAYLRDNGppPKRAHISYSKDDGVTWTRARDTEIPNPGTSLENIRLRNGN 361
WP_013564483 240 rGATWNTGrMIP-GIFAIQPAVVERSDGSLVAYCRNAGa-GRRILSATSNDGGVTWSEAIETTLPNPGAGVDAIRLASGK 317
WP_013665185 232 dGKSWRPSkPIA-GRGNIQPALIRRKQGDIIAYMRDSGdaPARIQQSISMDGGETWTVARKTEIPN-TASVEVIRLLDGR 309
WP_014020105 235 dGTTWFPSkPLV-GRGPIQPALGQRENGEIMAIMRDSGdaPTRIHKSYSQDEGMTWSASEKTSIPN-TASVELLVLDNGT 312
WP_067550617 233 hGKTWTPSlPLV-GRGPIQPALIQKKDGTLAAYLRDSGdaPGRVQYSESKNEGYTWTASQKTTIPN-TASVEVLKLKDGR 310
WP_110173263 266 sGATWKASdPLV-GGGNIQPALARRRDGTIVAYMRDNGpaPKRVHVSESRDRGETWTTVSDGSLPNPGTSVDVLVLKSGR 344
WP_083731940 280 dGAHWYASkPLI-GFGNIQPAVLRRDDGTLIAYMRENGp-RKHIRVCESKDDGITWGPVTESVLVNPGSGLDGVRLKNGH 357
WP_010040162 700 gGKTWTASqPLA-GFGSIQPAVLERKDGTLVAYMRENGv-FKKVRACESKDRGESWGTVYSTDLINPGSGLDAVRLASGN 777
WP_119754826 283 dGEHWQFSnPVL-GGAGIQPTVAIKKDSTLVAYLRDNGppPQRMQHTMSPDKGMTWSIAKDDTLPNPGAGFDMVTLPNGD 361
SQF98076     304 LLVALNDLQDGRFKLSLYGTDAkMDNWHSLRDLDKSPdplgapfspeafkeimgnefrdssgaqrqpleaqflsnldtrv 383
WP_011684414 362 WIMVYNDLEQGRYSLVAAMSDDeGATWKWKRHLDGSPsga---------------------------------------- 401
WP_013564483 318 FVLVYNDTEIGRHSLAVALSNDeGRTWNPPRFLERQPpd----------------------------------------- 356
WP_013665185 310 WLLVGNDVDDGRYQLSLYLSEDeGTSWKLSTLLEADDkk----------------------------------------- 348
WP_014020105 313 WLFLGNDIDDGRYRISLYISDDeGQTWRGKIYLEDEKkd----------------------------------------- 351
WP_067550617 311 WAFVGNDQSDGRYRLSIYLSDDeGQTWKWKFPVENHEps----------------------------------------- 349
WP_110173263 345 WALVYNDLERGRQSLAISLSSDeGRTWPVTRHLERDPdgat--------------------------------------- 385
WP_083731940 358 WLLVYNDTQKGRNSLAVSISTDeGRSWKWTRHLERQEe------------------------------------------ 395
WP_010040162 778 WLIVYNDTVKGRSRLAVSLSDDeGKTWKWTRHLEKHEt------------------------------------------ 815
WP_119754826 362 WLMVFNDTEVERFNLSVALSDDeGKTWRWKRSLENDTrtk---------------------------------------- 401
SQF98076     384 csprgceFEYEYPYFIRSPDGMYHVVYSWNN---------------TFIKHVTFNDAWLS 428
WP_011684414 402 -----rtSQYHYPSVIQARDGAIHVTYSYFTpe------------gKAIKHVRFNEDWVK 444
WP_013564483 357 ------qGAFHYPSILQTRDGQIHVLYTAGKah-----------rgETIRHAVFHESWLG 399
WP_013665185 349 ------kLSCSYPSIVQSTDGFIHLSYSYHVts-----------dkKSIKYLKISPDDIK 391
WP_014020105 352 ------vGGFSYPSLIQDIDGMVHITYSYHLne-----------kgKSIKYLKIDPKNF- 393
WP_067550617 350 ------sGSYSYPSLIQSEDGLLHLTYSYHLss-----------tqKSIKHVVVNPQLIP 392
WP_110173263 386 ---gdatGQYHYPSIIQSKDGMIHVTYSIFLppaqsakdaqgrvlrKSIKHAVFDEMWVE 442
WP_083731940 396 -------GSYHYPAVIQGSDGTIHVVYSYFVtg------------gKSMKHASFDEAWVQ 436
WP_010040162 816 -------GQYHYPAVIQSKDGAVHAVYSYFVad------------gKSMKHARFDEAWVK 856
WP_119754826 402 -----daTSSHYPSVIAGADGIIHVVYSYHRddv---------kpgKTIKYASFPVAWIK 447
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